Region | Title | System | Version | Edition | Languages | Serial | Status |
| Yoot Tower The Tower II | PC | | Original | | 85083 | |
| You Are Empty | PC | 1.1 | Original | | Part # 27583DV | |
| You Don't Know Jack | PC | | Not for Resale | | W0735330 | |
| You Don't Know Jack | PC | 1.0 | Original | | | |
| You Don't Know Jack | PC | 1.0 | Original | | | |
| You Don't Know Jack | PC | 1.01D | Original | | | |
| You Don't Know Jack | PC | 1.01D | Original | | | |
| You Don't Know Jack | PC | 1.01D | Original | | | |
| You Don't Know Jack | PC | 1.02 | Rerelease | | | |
| You Don't Know Jack Censored | PC | 1.0 | Original | | | |
| You Don't Know Jack: 5th Dementia | PC | 1.054 | Original | | | |
| You Don't Know Jack: Louder! Faster! Funnier! | PC | 1.0 | Original | | | |
| You Don't Know Jack: Movies | PC | | Original | | | |
| You Don't Know Jack: Movies | PC | | Original | | | |
| You Don't Know Jack: Offline | PC | | Original | | | |
| You Don't Know Jack: Question Pack | PC | 1.0 | Original | | | |
| You Don't Know Jack: Sports | PC | | Original | | | |
| You Don't Know Jack: Sports | PC | | Rerelease | | | |
| You Don't Know Jack: Sports | PC | | Sports 3-Pack | | W0735410 | |
| You Don't Know Jack: Sports | PC | | Original | | | |
| You Don't Know Jack: Television | PC | 1.0.0.0 | Original | | | |
| You Don't Know Jack: Volume 2 | PC | | Rerelease | | | |
| You Don't Know Jack: Volume 2 | PC | | Original | | | |
| You Don't Know Jack: Volume 2 | PC | 1.0 | | | | |
| You Don't Know Jack: Volume 3 | PC | | Rerelease | | | |
| You Don't Know Jack: Volume 3 | PC | 1.0 | Original | | | |
| You Don't Know Jack: Volume 3 | PC | 1.0.0.0 | Original | | | |
| You Don't Know Jack: Volume 4: The Ride (Disc 1) | PC | | Rerelease | | | |
| You Don't Know Jack: Volume 4: The Ride (Disc 1) | PC | | Special Collector's Edition | | | |
| You Don't Know Jack: Volume 4: The Ride (Disc 2) | PC | | Original | | | |
| You Don't Know Jack: XL You Don't Know Jack: X-TRA LARGE | PC | | Original | | | |
| Yu-Gi-Oh! Maximillion Pegasus | PC | | Original | | | |
| Yu-Gi-Oh! Online | PC | | USB Duelpass Key Bundle | | 2346-CD | |
| Yu-Gi-Oh! Online | PC | | Shonen Jump | | | |
| Yu-Gi-Oh! Power of Chaos: Joey the Passion | PC | | Original | | S2344810 | |
| Yu-Gi-Oh! Power of Chaos: Kaiba the Revenge | PC | | Original | | S2344710 | |
| Yu-Gi-Oh! Power of Chaos: Trial Version | PC | | Demo, Exclusive Shonen Jump Edition | | | |
| Yu-Gi-Oh! Power of Chaos: Yugi the Destiny | PC | | Original | | 23450/23446 | |
| Yu-Gi-Oh! Power of Chaos: Yugi the Destiny | PC | | | | | |
| Yu-Gi-Oh! Seto Kaiba | PC | | McDonald's Mighty Kids Meal | | | |
| The Yukon Trail | PC | 1.0 | Rerelease | | | |
| The Yukon Trail | PC | 1.1 | Original | | | |
| The Yukon Trail | PC | 1.1 | Original | | | |
| The Yukon Trail | PC | 1.12 | Rerelease | | PYT744CE-CD | |
| Yume Miru Kusuri: A Drug That Makes You Dream | PC | | Original | | P-014 | |
| Z | PC | | Original | | | |
| Zaero Zaero Add-On Pack for Quake II | PC | 1.0 | Original | | | |
| ZanZarah: The Hidden Portal | PC | 1.01 | Original | | | |
| Zapitalism! Deluxe | PC | | | | | |
| Zapper Zapper: One Wicked Cricket! | PC | 1.0 | Scholastic | | Part # CDR9-57451-X | |
| Zebco Pro Fishing 3D | PC | | Smart Saver | | PFG844AE-CD | |
| Zebco Pro Fishing 3D: Tournament Edition | PC | | Original | | 21365.101.US | |
| Zeitgeist | PC | | Original | | CD-C95-1172-0 | |
| Zeppelin! Zeppelin: Giants of the Sky | PC | | Original | | 042840101 | |
| Zero Critical | PC | | Original | | | |
| Zero Divide Zero Divide: Techno Warrior | PC | | Interplay Rerelease | | CD-C95-1170-0 | |
| Zero Zero | PC | | Original | | | |
| Zesty Bytes | PC | | Original | | | |
| Zeus: Le Maître de l'Olympe | PC | 1.0.0.0 | BestSeller Series | | | |
| Zeus: Master of Olympus | PC | 1.0 | Original | | | |
| Zeus: Master of Olympus | PC | 1.0.0.0 | Original | | | |
| Zeus: Master of Olympus | PC | 1.1 | The Great Empires Collection II | | | |
| Zoboomafoo Animal Kids | PC | 1.0 | Original | | 14000-CD1 | |
| Zoboomafoo: Animal Alphabet | PC | 1.0 | Original | | 02251 | |
| Zoboomafoo: Creature Quest | PC | 1.0 | Original | | 381553-CD | |
| Zodiac 50 Game Pack Vol. 2 | PC | | Original | | | |
| Zodiac Casino Pack | PC | | Original | | | |
| Zombie Bowl-o-Rama | PC | | Original | | 1000-10712 | |
| Zombie Wars | PC | 1.0R | Game Empire Series | | | |
| Zombieville | PC | | | | | |
| Zone Raiders | PC | 1.26 | Original | | CDRM1363590 | |
| Zoo Empire | PC | | Original | | | |
| Zoo Tycoon | PC | | Press Kit | | | |
| Zoo Tycoon | PC | 10.10.00.0006 | Original | | 0801 Part No. X08-30525 | |
| Zoo Tycoon | PC | 10.10.00.0009 | Zoo Tycoon: Complete Collection | | 0603 Part No. X09-79593, 0803 Part No. X10-10290 | |
| Zoo Tycoon 2 | PC | 20.10.00.0026 | Original | | 0804 Part No. X10-74059 | |
| Zoo Tycoon 2 | PC | 20.11.00.0007 | Rerelease | | 0804 Part No. X10-74059 | |
| Zoo Tycoon 2: African Adventure | PC | 1.00.0000 | Original | | 0206 Part No. X12-15023-01 | |
| Zoo Tycoon 2: Endangered Species | PC | | Original | | 0705 Part No. X11-45794 | |
| Zoo Tycoon 2: Extinct Animals | PC | 32.10.0.9 | Original | | 0707 Part No. X13-85741-01, X13-85741-01 | |
| Zoo Tycoon 2: Marine Mania | PC | | Original | | 0706 Part No. X12-79927-01 | |
| Zoo Tycoon 2: Marine Mania | PC | | Original | | 0706 Part No. X12-79927-01 | |
| Zoo Tycoon 2: Ultimate Collection (Disc 1) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72299-01 | |
| Zoo Tycoon 2: Ultimate Collection (Disc 2) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72305-01 | |
| Zoo Tycoon 2: Ultimate Collection (Disc 3) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72309-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 1) | PC | | Original | | 0806 Part No. X12-80044-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 2) | PC | | Original | | 0806 Part No. X12-80045-01 | |
| Zoo Tycoon: Dinosaur Digs | PC | | Original | | 0302 Part No. X08-63367 | |
| Zoo Tycoon: Dinosaur Digs | PC | 1.0 | Original | | 0302 Part No. X08-63367 | |
| Zoo Tycoon: Marine Mania & Dinosaur Digs Zoo Tycoon Expanded | PC | | Original | | 0802 Part No. X08-90495 | |
| Zoo Tycoon: Marine Mania & Dinosaur Digs | PC | 12.04.00.0009 | Zoo Tycoon: Complete Collection | | 0603 Part No. X09-79601, 0803 Part No. X10-10291 | |
| Zoo Tycoon: Ultimate Animal Collection | PC | | Original | | | |
| Zoo Tycoon: Ultimate Animal Collection | PC | | Rerelease | | | |
| ZooG Genius: Language Arts, History & Geography | PC | | Original | | G2240 | |
| ZooG Genius: Math, Science & Technology | PC | | Original | | G2236 | |
| Zoombinis: Island Odyssey | PC | 1.0 | Original, Scholastic | | 19531152C SP4, 381664-CD, 9531152C SP | |
| Zoombinis: Logical Journey | PC | 2.0 | Scholastic | | 380933-CD SP2 | |
| Zoombinis: Logical Journey | PC | 2.0 | Rerelease | | 3809330-CD | |
| Zoombinis: Logical Journey | PC | 2.0 | Original, Adventure Workshop: 1st-3rd Grade (7th Edition) | | 10115-CD3, 380933-CD | |
| Zoombinis: Logical Journey | PC | 2.1 | Adventure Workshop: 4th-6th Grade: 5th Edition | | 383332-CD2 | |
| Zoombinis: Mountain Rescue | PC | 1.0 | Scholastic | | 380860-CD SP1, 380860-CD WP5, 380860-CD WP6 | |
| Zoombinis: Mountain Rescue | PC | 1.1 | | | 380860A-CD | |
| Zoombinis: Mountain Rescue | PC | 1.1 | Scholastic | | 380860A-CD | |
| Zoop Zoop: America's Largest Killer of Time! | PC | 1.0 | Expert Software: Gamers Choice | | 08652 60930 | |
| Zootopia | PC | | KidSoft Select | | Part # 70466-D | |
| The Zork Anthology | PC | 1.0 | Original | | | |
| Zork Classics: Interactive Fiction | PC | 1.00 | Original | | Part No. 1001078.101.US | |
| Zork Nemesis: The Forbidden Lands (Disc 1) | PC | 1.0 | Original | | CDD-3112-101-US | |
| Zork Nemesis: The Forbidden Lands (Disc 1) | PC | 1.0 | Rerelease | | 1000168.101.US | |
| Zork Nemesis: The Forbidden Lands (Disc 3) | PC | 1.0 | Original | | 1000168.103.US, CDD-3112-103-U3 | |
| Zork: Grand Inquisitor | PC | | Sony OEM DVD-ROM Kit Edition | | 1000446.101.US | |
| Zork: Grand Inquisitor | PC | | DVD-ROM | | 1000600.101.US | |
| Zork: Grand Inquisitor | PC | | Bundle Version Gateway OEM (DVD-ROM) | | 1000676.101.US | |
| Zork: Grand Inquisitor (Disc 1) | PC | 2.0 | Original | | 1000026.101.US | |
| Zork: Grand Inquisitor (Disc 2) | PC | 2.0 | Original | | 1000026.102.US | |
| Zorro: A Cinematic Action Adventure | PC | | Original | | | |
| Zorro: A Cinematic Action Adventure | PC | | Original | | | |
| ZPC Zero Population Count | PC | 1.0 | Original | | 04-11315CD | |
| Zuma | PC | | Best Buy Games | | | |
| Zuma Deluxe | PC | 1.0 | Game of the Year | | | |
| Zuma Deluxe | PC | 1.0 | Rerelease | | | |
| Zuma Deluxe | PC | 1.0 | Rerelease | | | |
| Zuma's Revenge! | PC | | Limited Edition Lunch Box | | ZUMR-11-00918 06/11 11-00150 | |
| Zuma's Revenge! & Peggle Zuma's Revenge! | PC | | Original | | 10-00623 07/10 10-00172 | |
| Zurk's Li'l Safari 1: A Magical Journey into Letters and Numbers | PC | | Original | | 0055-000-0612-A | |