Region | Title | System | Version | Edition | Languages | Serial | Status |
| Scooby-Doo! Le Livre des Ténèbres | GC | | Original | | DL-DOL-GC3F-FRA | |
| SRS: Street Racing Syndicate | GC | | Original | | DL-DOL-GCSE-USA | |
| SRS: Street Racing Syndicate | GC | | Original | | DL-DOL-GCSP-EUR | |
| SRS: Street Racing Syndicate | GC | Rev 1 | Original | | DL-DOL-GCSP-EUR | |
| Speed Kings | GC | | Original | | DL-DOL-GDCE-USA | |
| Shinki Sekai Evolutia 神機世界エヴォルシア | GC | | Original | | DL-DOL-GEVJ-JPN | |
| Star Fox: Assault スターフォックス アサルト | GC | | Original | | DL-DOL-GF7J-JPN | |
| Street Hoops | GC | | Original | | DL-DOL-GHPE-USA | |
| Scooby-Doo! Nacht der 100 Schrecken | GC | | Original | | DL-DOL-GIHD-NOE | |
| Scooby-Doo! Night of 100 Frights | GC | Rev 1 | Original | | DL-DOL-GIHE-USA | |
| Scooby-Doo! La Nuit des 100 Frissons | GC | | Original | | DL-DOL-GIHF-FRA | |
| Space Raiders スペース レイダース | GC | | Original | | DL-DOL-GIJJ-JPN | |
| Space Raiders 스페이스 레이더스 | GC | | Original | | DL-DOL-GIJK-KOR | |
| Shonen Jump's One Piece: Pirates' Carnival | GC | | Original | | DL-DOL-GIPE-USA | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Samurai Jack: The Shadow of Aku | GC | | Original | | DL-DOL-GJCE-USA | |
| Samurai Jack: The Shadow of Aku | GC | | Original | | DL-DOL-GJCP-EUR | |
| Star Wars: Jedi Knight II: Jedi Outcast | GC | | Original | | DL-DOL-GJKD-NOE | |
| Star Wars: Jedi Knight II: Jedi Outcast | GC | | Original | | DL-DOL-GJKF-FRA | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2D-NOE | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2F-FRA | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2I-ITA | |
| Il Signore degli Anelli: Il ritorno del Re | GC | | Original | | DL-DOL-GKLI-ITA | |
| Scaler | GC | | Original | | DL-DOL-GKUE-USA | |
| Special Jinsei Game Special 人生ゲーム | GC | | Original | | DL-DOL-GLIJ-JPN | |
| Il Signore degli Anelli: Le Due Torri | GC | | Original | | DL-DOL-GLOI-ITA | |
| Star Wars: Rogue Squadron III: Rebel Strike | GC | | Original | | DL-DOL-GLRD-NOE | |
| Star Wars: Rogue Squadron III: Rebel Strike | GC | | Original | | DL-DOL-GLRF-FRA | |
| Star Wars: Rogue Squadron III: Rebel Strike | GC | | Original | | DL-DOL-GLRP-EUR | |
| Super Monkey Ball 2 スーパーモンキーボール2 | GC | | Original | | DL-DOL-GM2J-JPN | |
| Super Mario Sunshine 슈퍼 마리오 선샤인 | GC | | Original | | DL-DOL-GMSE-KOR | |
| Super Mario Sunshine スーパーマリオサンシャイン | GC | Rev 1 | Original | | DL-DOL-GMSJ-JPN | |
| Shonen Jump's One Piece: Grand Adventure | GC | | Original | | DL-DOL-GOQE-USA | |
| Spawn: Armageddon | GC | | Original | | DL-DOL-GPWE-USA | |
| Spawn: Armageddon | GC | | Original | | DL-DOL-GPWP-EUR | |
| Super Robot Taisen GC スーパーロボット大戦GC | GC | | Original | | DL-DOL-GRWJ-JPN | |
| Summoner: La Déesse Réincarnée | GC | | Original | | DL-DOL-GS2F-FRA | |
| Summoner: A Goddess Reborn | GC | | Original | | DL-DOL-GS2P-EUR | |
| SX Superstar | GC | | Original | | DL-DOL-GS3E-USA | |
| SX Superstar | GC | | Original | | DL-DOL-GS3P-EUR | |
| Shrek Extra Large | GC | | Original | | DL-DOL-GS9E-USA | |
| Shrek Extra Large | GC | | Original | | DL-DOL-GS9P-EUR | |
| Star Fox Adventures スターフォックスアドベンチャー | GC | Rev 1 | Original | | DL-DOL-GSAJ-JPN | |
| Smashing Drive | GC | | Original | | DL-DOL-GSDE-USA | |
| Shaman King: Soul Fight シャーマンキング ソウルファイト | GC | Rev 1 | Original | | DL-DOL-GSEJ-JPN | |
| SpyHunter | GC | | Original | | DL-DOL-GSHE-USA | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| Spider-Man | GC | | Original | | DL-DOL-GSMD-NOE | |
| Spider-Man | GC | Rev 1 | Player's Choice | | DL-DOL-GSME-USA | |
| Spider-Man | GC | | Original | | DL-DOL-GSMF-FRA | |
| Spider-Man スパイダーマン | GC | | Original | | DL-DOL-GSMJ-JPN | |
| Spider-Man | GC | Rev 1 | Player's Choice | | DL-DOL-GSMP-UKV | |
| Smuggler's Run: Warzones | GC | | Original | | DL-DOL-GSRE-USA | |
| Sega Soccer Slam セガ サッカースラム | GC | | Original | | DL-DOL-GSSJ-JPN | |
| Superman: Shadow of Apokolips | GC | | Original | | DL-DOL-GSUP-EUR | |
| Star Wars: Rogue Squadron II: Rogue Leader | GC | | Original | | DL-DOL-GSWD-NOE | |
| Star Wars: Rogue Squadron II: Rogue Leader | GC | | Original | | DL-DOL-GSWI-ITA | |
| Star Wars: Rogue Squadron II スター・ウォーズ ローグ スコードロン Ⅱ | GC | | Original | | DL-DOL-GSWJ-JPN | |
| Star Wars: The Clone Wars | GC | | Original | | DL-DOL-GSXD-NOE | |
| Star Wars: The Clone Wars | GC | | Original | | DL-DOL-GSXF-FRA | |
| Star Wars: La Guerra dei Cloni | GC | | Original | | DL-DOL-GSXI-ITA | |
| Star Wars: The Clone Wars スター・ウォーズ クローン戦争 | GC | | Original | | DL-DOL-GSXJ-JPN | |
| Star Wars: Las Guerras Clon | GC | | Original | | DL-DOL-GSXS-ESP | |
| Shrek Super Party | GC | | Original | | DL-DOL-GSYE-USA | |
| Shrek Super Party | GC | | Original | | DL-DOL-GSYP-EUR | |
| Starsky & Hutch | GC | | Original | | DL-DOL-GT5E-USA | |
| Shadow the Hedgehog シャドウ・ザ・ヘッジホッグ | GC | | Original | | DL-DOL-GUPJ-JPN | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAD-NOE | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAE-USA | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAF-FRA | |
| Swingerz Golf 와!와! 골프 | GC | | Original | | DL-DOL-GWGE-KOR | |
| Swingerz Golf | GC | | Original | | DL-DOL-GWGE-USA | |
| Star Wars: Rogue Squadron III スター・ウォーズ ローグ スコードロンⅢ | GC | | Original | | DL-DOL-GWXJ-JPN | |
| SSX 3 | GC | | Original | | DL-DOL-GXBE-USA | |
| SSX 3 | GC | | Original | | DL-DOL-GXBJ-JPN | |
| Sonic Riders ソニックライダーズ | GC | | Original | | DL-DOL-GXEJ-JPN | |
| Sonic Riders | GC | | Original | | DL-DOL-GXEP-EUR | |
| SSX on Tour | GC | | Original | | DL-DOL-GXOP-EUR | |
| SSX on Tour | GC | | Original | | DL-DOL-GXOX-FRA | |
| Surf's Up | GC | | Original | | DL-DOL-GXUE-USA | |
| SD Gundam: Gashapon Wars SDガンダム ガシャポンウォーズ | GC | | Taikenban | | DL-DOL-PGPJ-JPN | |
| Slipstream 5000 | PC | | Dice | | DMM 000009 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 001631 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Dice | | DMM 001631 | |
| Sinbad the Seaman | PC | | Dice | | DMM 003550 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Dice | | DMM 011143 | |
| Solar Crusade | PC | | Dice | | DMM 011396 | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | Dice | | DMM 012774 | |
| SimCity Enhanced CD-ROM | PC | | Dice | | DMM 014129 | |
| Star Trek: Judgment Rites | PC | | Dice | | DMM 014150 | |
| Solar Crusade | PC | | Dice | | DMM 031419 | |
| S.T.O.R.M. (Disc 1) | PC | | Dice | | DMM 031730 | |
| Sin SiN | PC | | Demo | | DMO-1000076.101.US | |
| Shaftdiver シャフトダイバー | PC | 1.0 | Original | | DNAS-SDVR | |
| Saddle Up: Time to Ride | PC | 1.00.000 | Original | | DPV1.0, PCO437CD | |
| Summer Athletics 2009 | XBOX360 | | Original | | DT-2006 | |
| SDevTC: Version 2.4 | PC | 2.4 | Original | | DTL-S2200 | |
| Street Fighter V | PC | | Original | | DV1-97242-00EUR | |
| Street Fighter 30th Anniversary Collection | PC | | Original | | DV1-97251-00EUR | |
| Star Wars: The Force Unleashed II | PC | 1.1 | Cosmi | | DVD248D1 v 1.1.0.1 | |
| Star Wars: Battlefront | PC | 1.2 | Cosmi | | DVD282D1; SJ032011 | |
| Star Wars: Battlefront II | PC | 1.1 | Cosmi (DVD-ROM) | | DVD283D1 | |
| Star Wars: Empire at War: Gold Pack | PC | 1.0.5.0 | Rerelease | | DVD284D1, SJ102010 | |
| Star Wars: Republic Commando | PC | 1.01 | Cosmi | | DVD287D1, SJ032011 | |
| Star Wars: The Clone Wars: Republic Heroes | PC | 1.0 | Cosmi | | DVD288D1 | |
| SpellForce: Universe (Disc 2) | PC | 2.00 | Original | | DVD563CD | |
| SpellForce: Universe (Disc 1) | PC | 1.52 | Original | | DVD564CD | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Sega-Race TV セガ-レースTV | LINDBERGH | 1.002 | Lindbergh Yellow | | DVP-0044 | |
| Sega Network Taisen Mahjong MJ4 セガネットワーク対戦麻雀MJ4 | LINDBERGH | 7.000 | Lindbergh Red EX | | DVP-0049F | |
| Sega Network Taisen Mahjong MJ4 セガネットワーク対戦麻雀MJ4 | LINDBERGH | 8.003 | Lindbergh Red EX | | DVP-0049G | |
| StarHorse 2: Final Destination | LINDBERGH | 5.000 | Lindbergh StarHorse 2 | | DVP-0086D | |
| Sega Racing Classic | SRE | | RingWide | | DVR-0009A | |
| Sega Network Taisen Mahjong MJ5 セガネットワーク対戦麻雀MJ5 | SRE | | Original | | DVR-0027 | |
| Sega Network Taisen Mahjong MJ5 Evolution セガネットワーク対戦麻雀MJ5 EVOLUTION | SRE | | Original | | DVR-0071 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083D | |
| Sega Net Mahjong MJ Arcade セガNET麻雀MJ Arcade | SRE | | Original | | DVR-5055D | |
| Scholar Movie Magazine Soukan-gou スコラ MOVIE MAGAZINE 創刊号 | FMT | | Original | | DWDC 4815 | |
| Star Wars: Episode I: The Phantom Menace スター・ウォーズ エピソード1 ファントム・メナス | PC | | DigiCube PC | | DWOKD-00061 | |
| Sangokushi III 三國志Ⅲ | PC | 1.0 | Koei Teiban Series | | DWOKD-00071 | |
| The Silent Service: Chinmoku no Kantai 沈黙の艦隊 | PC-98 | | Original | | DWPC3808 | |
| SD Gundam: GGeneration DA SDガンダム GジェネレーションDA | PC | 1.00 | DigiCube PC Series | | DWRMS-00158 | |
| Sega Rally 2: Sega Rally Championship (Install Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally 2: Sega Rally Championship (Play Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Shanghai: Dynasty 上海ダイナスティ | PC | 1.2 | DigiCube PC | | DWRPS-00055 | |
| Sakura Taisen 3: Paris wa Moeteiru ka: Desktop Accessories サクラ大戦3 ~巴里は燃えているか~ デスクトップアクセサリーズ | PC | | Tokubetsu Genteiban B | | DWWWC-50121~50123 | |
| Space Hulk | PC | | Original | | E2105CCD | |
| Syndicate Plus Syndicate+ | PC | | CD-ROM Classics: RComp | | E2825CCD | |
| SSN-21 Seawolf | PC | | EA CD-ROM Classics | | E3205CXD | |
| Space Hulk: Vengeance of the Blood Angels | PC | | Original | | E348EDED | |
| Shockwave Assault | PC | | Original | | E354WCED | |
| System Shock | MAC | | Original | | EA 568407 | |
| Syndicate Wars | PC | | | | EA 768207 | |
| SSX Tricky SSX トリッキー | XBOX | | Original | | EA-004 | |
| SSX Tricky | XBOX | | Platinum Hits | | EA-004 | |
| The Simpsons: Road Rage | XBOX | | Original | | EA-019 | |
| Star Wars: Obi-Wan | XBOX | | Original | | EA-034 | |
| The Sims | XBOX | | Original | | EA-047 | |
| The Sims | XBOX | | Original | | EA-047 | |
| SSX 3 | XBOX | | Original | | EA-060 | |
| SSX 3 | XBOX | | Original | | EA-060 | |
| Le Seigneur des Anneaux: Le Retour du Roi | XBOX | | Original | | EA-062 | |
| El Señor de los Anillos: El Retorno del Rey | XBOX | | Original | | EA-062 | |
| Il Signore degli Anelli: Il ritorno del Re | XBOX | | Original | | EA-062 | |
| The Sims: Bustin' Out 模擬市民 純屬意外 | XBOX | | Original | | EA-067 | |
| The Sims: Bustin' Out | XBOX | | Original | | EA-067 | |
| Le Seigneur des Anneaux: Le Tiers Age | XBOX | | Original | | EA-095 | |
| El Señor de los Anillos: La Tercera Edad | XBOX | | Original | | EA-095 | |
| Il Signore degli Anelli: La Terza Era | XBOX | | Original | | EA-095 | |
| SSX on Tour | XBOX | | Promo | | EA-130 | |
| SSX on Tour | XBOX | | Original | | EA-130 | |
| SSX on Tour | XBOX | | Original | | EA-130 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Les Simpson: Le Jeu | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| Die Simpsons: Das Spiel | XBOX360 | | Original | | EA-2057 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Shadows of the Damned シャドウ オブ ザ ダムド | XBOX360 | | Original | | EA-2346 | |
| The Sims 2 | XBOX | | Original | | EA-907 | |
| The Sims 2 | XBOX | | Original | | EA-907 | |
| SimCity Societies Destinations 模擬城市:度假天堂 | PC | | Original | | EA208707 | |
| The Saboteur | PC | | Original | | EAD07706314D | |
| Shogun: Total War: The Mongol Invasion | PC | | Original | | EAD08803486D | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | | Original | | EAD08803525D | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | | Original | | EAD08803525D1 | |
| Scarab S.C.A.R.A.B. | PC | | Original | | EAE08801181D | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | EAE088019651D | |
| Shogun: Total War (Disc 2) | PC | | Rerelease | | EAE088019651D2 | |
| Sid Meier's Gettysburg! | PC | 1.0 | Play The Games Vol. 2 | | EAG 08801356D | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | EAG 08801356F | |
| Shogun: Total War (Disc 1) | PC | | Original | | EAG08801965D1 | |
| Shogun: Total War (Disc 2) | PC | | Original | | EAG08801965D2 | |
| Sid Meier's Alien Crossfire | PC | 4.0 | Original | | EAG08902814D | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Original | | EAG08903149D | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 1) (Disco d'Installazione) | PC | 1.0 | EA Classics | | EAI08004073BD | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 2) (Disco d'Installazione) | PC | 1.0 | EA Classics | | EAI08004073BD2 | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 3) (Disco di Gioco) | PC | 1.0 | EA Classics | | EAI08004073BD3 | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 1) (Disco d'Installazione) | PC | | Original | | EAI08004073D | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 2) (Disco d'Installazione) | PC | | Original | | EAI08004073D2 | |
| Il Signore degli Anelli: Il ritorno del Re (Disc 3) (Disco di Gioco) | PC | | Original | | EAI08004073D3 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | | | EAP08801965D1 | |
| Shogun: Total War (Disc 2) | PC | 1.0 | | | EAP08801965D2 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| The Saboteur | PC | 1.0 | Original | | EAX07706314D | |
| Syndicate | PC | | Original | | EAX07708007D | |
| The Secret World (Disc 1) | PC | | Original | | EAX07709446D | |
| The Secret World (Disc 2) | PC | | Original | | EAX07709446D2 | |
| Superbike World Championship | PC | | | | EAX08801929D | |
| Syndicate Wars | PC | | CD-ROM Classics | | EAX08803095D2 | |
| Sub Command (Disc 1) Sub Command: Akula Seawolf 688(I) | PC | 0.1.0.0 | Original | | EAX08803483D | |
| Sub Command (Disc 2) Sub Command: Akula Seawolf 688(I) | PC | 0.1.0.0 | Original | | EAX08803483D1 | |
| Sid Meier's SimGolf | PC | | Original | | EAX08803576D | |
| Shogun: Total War (Sneak Preview) | PC | | | | EAX08901965DD | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | Original | | EAX08902788D | |
| Superbike 2001 | PC | | Original | | EAX08903308D | |
| Superbike 2001 (Documents) | PC | | EA Classics | | EAX08903632D2 | |
| Sports Car GT (Manuale Elettronico) | PC | | Original | | ECA430 DK2 | |
| Syndicate Wars | PC | | Collezione CD-Rom by C.T.O. | | ECA545 | |
| Singles: Flirt Up Your Life! | PC | | Original | | ECD000808K | |
| Singles 2: Wilde Zeiten | PC | | Original | | ECD008010M | |
| Sacred 2: Fallen Angel (Disc 1) | PC | 2.0.2 Build 1371 | Original | | ECD008419D | |
| Sacred 2: Fallen Angel (Disc 2) | PC | 2.0.2 Build 1371 | Original | | ECD008419D | |
| Das Schwarze Auge: Satinavs Ketten | PC | | Limitierte Erstauflage | | ECD008798M ECD008799M ECD008907K ECD900830D 23032012-00 | |
| Sword of the Stars II: Lords of Winter | PC | | Original | | ECD008844D 20111031-01 | |
| Secret Files 2: Puritas Cordis | PC | | Original | | ECD900341D | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD950001D | |
| Shinchou Mahjong 信長麻雀 | XBOX | | Original | | EF-001 | |
| Space Invada!! Type Shinai to Tama ga Denai. SPACE INVA打!! / SPACE INVADERS!! タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Stars! | PC | 2.7a | Original | | EI-1036 | |
| Screamer | PC | | Award Winners No. 1 | | EI-1041 | |
| Sheep | PC | | | | EI-1246 | |
| Sheep | PC | | Original | | EI-1247 | |
| Sonic R | PC | | Xplosiv | | EI-1263 | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original | | EI-1266-1 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega Touring Car Championship | PC | 1.0 | Xplosiv | | EI-1306 | |
| Sonic R | PC | | Megapak 10 | | EI-1328 | |
| Sonic 3D: Flickies' Island | PC | | Megapak 10 | | EI-1329 | |
| Sheep | PC | | Megapak 10 | | EI-1420 GERMAN | |
| Supercar Street Challenge | PC | | Xplosiv | | EI-1477 EUROPEAN | |
| Starsky & Hutch | PC | | Rerelease | | EI-1510 EUROPEAN | |
| Sonic R | PC | | Xplosiv | | EI-1530 EUROPEAN | |
| Shanghai: Second Dynasty | PC | | Xplosiv | | EI-1588 ENGLISH | |
| Sega Marine Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1606 | |
| Sega Bass Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1607 | |
| Starship Troopers | PC | 0.1.0.6 | Demo | | EI-1958 EUROPEAN | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Stranger | PC | | Original | | EI-2237 ML02 | |
| Strike Commander ストライクコマンダー | PC | 1.01 | Original | | EID-4001 | |
| Starsky & Hutch | XBOX | | Original | | EM-005 | |
| Syndicate Wars シンジケートウォーズ | PC | | Original | | EMW-4021 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | Original | | EMW-4034 | |
| SimPeople シムピープル | PC | 1.0 | Original | | EMW-4061 | |
| Shogun: Total War (Disc 1) ショーグン トータル ウォー | PC | | Original | | EMW-4070 | |
| Shogun: Total War (Disc 2) ショーグン トータル ウォー | PC | | Original | | EMW-4070 | |
| SimCity 3000 Special Edition Upgrade Kit シムシティ3000 スペシャルエディション アップグレード・キット | PC | 2.0.958.0 | Original | | EMW-4071, EMW-4073, EMWV-707 | |
| SimCity 3000 Special Edition シムシティ3000 スペシャルエディション | PC | | Original | | EMW-4080 | |
| SimCity 4 (Disc 1) シムシティ4 | PC | 1.0.233.0 | Original | | EMW-4121 | |
| SimCity 4 (Disc 2) シムシティ4 | PC | 1.0.233.0 | Original | | EMW-4121 | |
| SimCity 4: Rush Hour: Expansion Pack シムシティ4 ラッシュ・アワー 拡張キット | PC | 1.1.613.0 | Original | | EMW-4131 | |
| The Sims 2 (Disc 1) ザ・シムズ2 | PC | 1.0.0.932 | Original | | EMW-4138 | |
| The Sims 2 (Disc 2) ザ・シムズ2 | PC | 1.0.0.932 | Original | | EMW-4138 | |
| The Sims 2 (Disc 3) ザ・シムズ2 | PC | 1.0.0.932 | Original | | EMW-4138 | |
| The Sims 2 (Disc 4) ザ・シムズ2 | PC | 1.0.0.932 | Original | | EMW-4138 | |
| SimPeople: Magical Dream! (Data Set) (Disc 1) シムピープル マジカルドリーム!データセット | PC | 1.1 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Magical Dream! (Data Set) (Disc 2) シムピープル マジカルドリーム!データセット | PC | 1.1 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Pets & Gardening! (Data Set) (Disc 1) シムピープル ペット&ガーデニング!データセット | PC | 1.0 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Pets & Gardening! (Data Set) (Disc 2) シムピープル ペット&ガーデニング!データセット | PC | 1.0 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Star Paradise! (Data Set) (Disc 1) シムピープル スター・パラダイス!データセット | PC | 1.0 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Star Paradise! (Data Set) (Disc 2) シムピープル スター・パラダイス!データセット | PC | 1.0 | SimPeople Kanzenban 3 | | EMW-4160 | |
| SimPeople: Vacation! (Data Set) シムピープル バケーション!データセット | PC | 1.0 | SimPeople Kanzenban 3 | | EMW-4160 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWB-7007 | |
| SimCity 3000 シムシティ3000 | PC | | EA Best Selections | | EMWB-7048 | |
| Superbike 2000 | PC | | EA Best Selections | | EMWB-7053 | |
| Sid Meier's Alpha Centauri: Kanzenban シド・マイヤーズ アルファ・ケンタウリ 完全版 | PC | | EA Best Selections | | EMWB-7057 | |
| SimCity 2000 Special Edition シムシティ2000スペシャルエディション | PC | 1.0 | EA Best Selection | | EMWD-701 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWD-711 | |
| Syndicate シンジケート | PC-98 | | Original | | ENP-7009 | |
| Strike Commander ストライク・コマンダー | PC-98 | | PC-98-you CD-ROM-ban | | ENP-7010 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Souzou Sozai: Europe no Mado Vol. 2 創造素材 ヨーロッパの窓 Vol.2 | PHOTO-CD | | Original | | ERV2 | |
| Sacred: La Leyenda del Arma Sagrada | PC | 1.8.80 | DVD-ROM | | ES v.1.8 DVD | |
| Scudetto 5 Scudetto Championship Manager 5 | XBOX | | Original | | ES-026 | |
| SimCity 2000 Special Edition | PC | | SoftKey | | ESC744BB-CD | |
| Scrabble Interactive: 2003 Edition | PC | | Focus Essential | | ESS493 | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Focus Essential | | ESS565 | |
| Scrabble Interactive: 2007 Edition | PC | 1.1.0 | Ubisoft eXclusive / Focus Essential | | ESS760 | |
| Supreme Commander | PC | 1.0.3189 | Focus Essential | | ESS762 | |
| Supermarket Mania | PC | | Original | | ESS772 | |
| Strange Cases: The Tarot Card Mystery | PC | | Original | | ESS827 | |
| Strong Bad's Cool Game for Attractive People | PC | 1.0.0.1 | Original | | EuroVideo-Artikel-Nummer 501883 | |
| Sam & Max Save the World Sam & Max: Season One | PC | | PC Game Bundle | | EuroVideo-Artikel-Nummer 502083 | |
| Sam & Max: Im Theater des Teufels Sam & Max: The Devil's Playhouse | PC | | Original | | EuroVideo-Artikel-Nummer 502083 | |
| Silmarils Collection | PC | | Original | | EuroVideo-Artikel-Nummer: 502063 | |
| Seikimatsu Taimaden Tsumugi-chan SOS 世紀末退魔伝つむぎちゃんSOS | PC | | Original | | EXC-0011 | |
| Sid Meier's Civilization V シド・マイヤーズ シヴィライゼーションⅤ | PC | | Kakaku Kaiteiban | | FBG007W000A10 | |
| Shin Onryou Senki 真怨霊戦記 | PCE | | Original | | FCCD5003 | |
| Sound Eye Julian (Disc 1) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 2) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 3) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 4) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Star Wars: Yoda Stories + Star Wars: Screen Entertainment | PC | 1.0 | | | FD005, LUC629 | |
| Sherlock Holmes Versus Jack the Ripper | XBOX360 | | Original | | FE-2003 | |
| Sherlock Holmes: Crimes & Punishments | XBOX360 | | Original | | FE-2015 | |
| Sega Worldwide Soccer PC | PC | | Fair Game | | FG-1281 | |
| Sega Touring Car Championship | PC | | Fair Game: Quality Value | | FG-1306 EUROPEAN | |
| Silent Nova サイレント ノヴァ | PC | | Original | | FGW-0003 | |
| Suomiseikkailu | PC | | Original | | FI6 | |
| St. Shirobara Gakuen Petit Mahjong: Enami Rina no Maki 聖白薔薇学園プチ★MAHJONG ~江波理菜の巻~ | PC | | Original | | FIVD-002 | |
| Soreike! Anpanman: Tanoshii Eigo Asobi それいけ! アンパンマン ~たのしいえいごあそび~ | FMT | | Original | | FMB-3010 | |
| Sniper Elite V2 | XBOX360 | | Original | | FO-2024 | |
| Sniper Elite III | XBOX360 | | Original | | FO-2051 | |
| Sonic & All-Stars Racing Transformed | PC | | Rerelease | | FSGSEGAPC146AU | |
| Steins;Gate 命運石之門 | XBOX360 | | Original | | FV-2008 | |
| Sharin no Kuni, Himawari no Shoujo 車輪の国、向日葵の少女 | XBOX360 | | Limited Edition | | FV-2017 | |
| Steins;Gate: Senkei Kousoku no Phenogram STEINS;GATE 線形拘束のフェノグラム | XBOX360 | | Limited Edition | | FV-2035 | |
| Super Power League FX スーパー・パワー・リーグFX | PC-FX | | Original | | FXHUD504 | |
| Sotsugyou R: Graduation Real 卒業R -Graduation Real- | PC-FX | | Original | | FXNAV602 | |
| Super Real Mahjong P.V FX スーパーリアル麻雀P・Ⅴ-FX | PC-FX | | Original | | FXNAX601 | |
| Shanghai: Banri no Choujou 上海 ~万里の長城~ | PC-FX | | Original | | FXNHE507 | |
| Sparkling Feather スパークリング・フェザー | PC-FX | | Original | | FXNHE739 | |
| Super PC Engine Fan Deluxe: Special CD-ROM Vol. 1 | PC-FX | | | | FXTIM003 | |
| Super PC Engine Fan Deluxe: Special CD-ROM Vol. 2 | PC-FX | | | | FXTIM004 | |
| Shiho Shashin-shuu SHIHO写真集 | PHOTO-CD | | Original | | FZ-JJ1YP0401 | |
| Shimada Youko: Quatre 島田陽・子カトル | PHOTO-CD | | Original | | FZ-JJ1YP0501 | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Demonstration-ban | | FZ-JJ9DSP-5G | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Demo-ban | | FZ-JJ9DSS-4K | |
| Sword & Sorcery ソード・アンド・ソーサリー | 3DO | | Demo-ban | | FZ-JJ9DSS-5H | |
| Shock Wave: Operation JumpGate ショック・ウェーブ ~オペレーション・ジャンプゲート~ | 3DO | | Demo-CD | | FZ-JJ9DSV-5D | |
| Scramble Cobra: Premium Version スクランブル・コブラ プレミアム・バージョン | 3DO | | Not for Sale | | FZ-JJ9PSC-5H | |
| Scramble Cobra | 3DO | | Original | | FZ-SE0404 | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Original | | FZ-SJ0404 | |
| Shanghai: Banri no Choujou: The Great Wall 上海 ~万里の長城~ | 3DO | | Original | | FZ-SJ1660 | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Original | | FZ-SJ1661 | |
| Sesame Street: Numbers セサミ・ストリート ~ナンバーズ~ | 3DO | | Original | | FZ-SJ1664 | |
| Secre Fuumin no Omochabako セクレ・フーミンのおもちゃ箱 | 3DO | | Original | | FZ-SJ2651 | |
| Sangokushi IV 三國志Ⅳ | 3DO | | Original | | FZ-SJ2853 | |
| Seimei Handan 姓名判断 | 3DO | | Original | | FZ-SJ4053 | |
| Strahl シュトラール | 3DO | | Original | | FZ-SJ4651 | |
| Surgical Strike サージカル・ストライク | MCD | | Original | | G-6044 | |
| SpellForce 2: Shadow Wars | PC | 1.0 | Bundle Version OEM | | G-SF02 | |
| Sanzennen Shokudou: Shoku Culture Simulation Game 三千年食堂 食カルチャーシミュレーションゲーム | MAC | | Original | | G012JAP-M | |
| Screamer Rally | PC | | Covermount | | G02 | |
| Sudoku | GAMEWAVE | | Original | | G230 | |
| Sengoku Shougi 戦国将棋 | PC | | Power Game 1800 Series | | GA-0001 | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.11 | Rerelease | | GAG744BE-CD | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Slave Pageant (Game Disc) | PC | | Original | | GC-020 | |
| Slave Pageant (Install Disc) | PC | | Original | | GC-020 | |
| The Sagara Family (Game Disc) | PC | | Original | | GC-026 | |
| The Sagara Family (Install Disc) | PC | | Original | | GC-026 | |
| Snow Sakura | PC | | Original | | GC030 | |
| Shin Sangoku Musou 3: Fan Disc 「真・三國無双3」ファンディスク | PC | | Hibaihin | | GCITY-65248 | |
| Street Fighter Zero 3 Upper | NAOMI | 1.001 | Original | | GDL-0002 | |
| Shikigami no Shiro II 式神の城II | NAOMI | 1.000 | Original | | GDL-0021 | |
| Senko no Ronde 旋光の輪舞 | NAOMI | 1.001 | Original | | GDL-0030 | |
| Super Shanghai 2005 スーパー上海2005 | NAOMI | 1.001 | Original | | GDL-0031 | |
| Super Shanghai 2005 スーパー上海2005 | NAOMI | 2.001 | Original | | GDL-0031A | |
| Search and Rescue Air Rescue | PC | | Grabit | | GDL024 | |
| SD Qlympics Olympic Challenge | PC | | Grabit | | GDL031 | |
| Stars! | PC | 2.70i | Grabit | | GDL051 | |
| SleepWalker | PC | | Grabit | | GDL061 | |
| Sheep | PC | 1.0.0.1 | Grabit | | GDL090 | |
| Sports Jam スポーツ・ジャム | NAOMI | 1.005 | Original | | GDS-0003 | |
| Slashout | NAOMI | 1.000 | Original | | GDS-0004 | |
| Shock Wave 지구공습 2019 | 3DO | | Original | | GDT-GA 101 | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 4.000 | Original | | GDX-0006C | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 5.000 | Original | | GDX-0006D | |
| Sega Network Taisen Mahjong MJ3 セガ・ネットワーク対戦麻雀MJ3 | CHIHIRO | 5.000 | Original | | GDX-0017D | |
| Sega Network Taisen Mahjong MJ3 Evolution セガ・ネットワーク対戦麻雀MJ3 EVOLUTION | CHIHIRO | 2.000 | Original | | GDX-0021A | |
| Sega Network Taisen Mahjong MJ3 Evolution-you Firmware Koushin Program セガ・ネットワーク対戦麻雀MJ3 EVOLUTION用ファームウェア更新プログラム | CHIHIRO | 1.000 | Original | | GDX-0023 | |
| Shutokou Battle X 首都高バトルX | XBOX360 | | Original | | GE-2001 | |
| Slave Zero スレイブゼロ | PC | | Original | | GFM-29002 | |
| Die Siedler 7 | PC | | Covermount | | GHDVD0215 | |
| Steam Heart's Perfect Collection: Hybrid CD-ROM スチームハーツ パーフェクトコレクション HYBRID CD-ROM | PC | | Original | | GIGA-970430 | |
| Stalingrad スターリングラード | PC | | Original | | GLA-00370 | |
| Sony DVD Test Disc | PS2 | | Original | | GLD-DR01 | |
| Sumida Yuki: Photo CD Portfolio 墨田ユキ フォトCDポートフォリオ | PHOTO-CD | | Original | | GLS-PH-08 | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Senkou no Ronde Duo 旋光の輪舞DUO | XBOX360 | | Limited Edition | | GR-2041 | |
| Shinsetsu Yumemi Yakata: Tobira no Oku ni Dareka ga... 真説・夢見館 扉の奥に誰かが… | SS | 1.000 | Original | | GS-9005 | |
| Shinsetsu Yumemi Yakata: Tobira no Oku ni Dareka ga... 真説・夢見館 扉の奥に誰かが… | SS | 1.000 | Original | | GS-9005 | |
| Sega Ages: Shukudai ga Tanto R セガエイジス 宿題がタントアール | SS | 1.06 | Original | | GS-9042 | |
| Sega Ages: Rouka ni Ichidanto R セガエイジス 廊下にイチダントアール | SS | 1.002 | Original | | GS-9043 | |
| Sega Ages: Space Harrier セガエイジス スペース・ハリアー | SS | 1.102 | Original | | GS-9108 | |
| Sega Ages: Space Harrier セガエイジス スペース・ハリアー | SS | 1.102 | Original | | GS-9108 | |
| Sega Ages: Memorial Selection Vol. 1 セガエイジス メモリアル・セレクションVOL.1 | SS | 1.002 | Original | | GS-9135 | |
| Sakura Taisen: Hanagumi Taisen Columns サクラ大戦 ~花組対戦コラムス~ | SS | 1.000 | Original | | GS-9138 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Disc 2) サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.002 | Shokai Tokutenban | | GS-9169 | |
| Sonic R ソニックR | SS | 1.002 | Original | | GS-9170 | |
| Shining Force III: Scenario 1: Outo no Kyoshin シャイニング・フォースⅢ シナリオ1 ~王都の巨神~ | SS | 2.005 | Original | | GS-9175 | |
| Shining Force III: Scenario 2: Nerawareta Miko シャイニング・フォースⅢ シナリオ2 ~狙われた神子~ | SS | 2.000 | Original | | GS-9188 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Disc 2) サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.004 | Original | | GS-9198 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Disc 3) サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.004 | Original | | GS-9198 | |
| Spin Busta | PC | 1.0 | Original | | GS0003 | |
| Sesamstrasse: Auf die Krümel, fertig, los! | PC | | Rerelease | | GSL854AG-CD | |
| Skipper & Skeeto: The Great Treasure Hunt | PC | | GSP/PC Ace Covermount | | GSPCD336A | |
| Song of the Deep | PC | | Original | | GTPC002-DL | |
| Susume! Taisen Puzzle-dama 進め!対戦ぱずるだま | KSGV | | Original | | GV027-J1 | |
| Susume! Taisen Puzzle-dama 進め!対戦ぱずるだま | KSGV | Rev A | Original | | GV027-J1 | |
| Shouhuzhe Zhi Jian II (Disc 1) 守护者之剑Ⅱ | PC | 1.0 | Original | | GXDZ-9014 | |
| Shouhuzhe Zhi Jian II (Disc 2) 守护者之剑Ⅱ | PC | 1.0 | Original | | GXDZ-9014 | |
| Shouhuzhe Zhi Jian II (Disc 3) 守护者之剑Ⅱ | PC | 1.0 | Original | | GXDZ-9014 | |
| Shouhuzhe Zhi Jian II (Disc 4) 守护者之剑Ⅱ | PC | 1.0 | Original | | GXDZ-9014 | |
| Shouhuzhe Zhi Jian II (Disc 5) 守护者之剑Ⅱ | PC | 1.0 | Original | | GXDZ-9014 | |
| Super Darius スーパー・ダライアス | PCE | | Original | | HACD 0003 | |
| Seiryuu Densetsu: Monbit 聖竜伝説モンビット | PCE | Rev 4 | Original | | HCD1018 | |
| Seiya Monogatari: Anearth Fantasy Stories 聖夜物語 | PCE | Rev 2 | Original | | HCD5071 | |
| Storybook Weaver Deluxe | PC | 1.2 | Rerelease | | HCD642-CD | |
| Sonic the Hedgehog CD ソニック・ザ・ヘッジホッグ CD | PC | | Rerelease | | HCJ-0104 | |
| Sonic Adventure | DC | 1.000 | Trial Version for E3 | | HDR-0001 | |
| Sega Rally 2 セガ・ラリー2 | DC | 1.04 | Original | | HDR-0010 | |
| Super Speed Racing スーパースピードレーシング | DC | 1.004 | Original | | HDR-0013 | |
| Shenmue: Ichishou Yokosuka (Shenmue Passport) シェンムー 一章 横須賀(シェンムーパスポート) | DC | 1.010 | Genteiban | | HDR-0031 | |
| Sonic Adventure International ソニックアドベンチャー・インターナショナル | DC | 1.003 | Original | | HDR-0043 | |
| Sakura Taisen: Hanagumi Taisen Columns 2 サクラ大戦 ~花組対戦コラムス2~ | DC | 1.000 | Original | | HDR-0046 | |
| Sega Tetris セガテトリス | DC | 2.000 | Original | | HDR-0073 | |
| Sakura Taisen (Omake Disc) サクラ大戦 | DC | 1.001 | Genteiban | | HDR-0089 | |
| Sakura Taisen (Disc 1) サクラ大戦 | DC | 1.009 | Genteiban | | HDR-0089 | |
| Sakura Taisen (Disc 2) サクラ大戦 | DC | 1.009 | Genteiban | | HDR-0089 | |
| Sega Marine Fishing セガマリンフィッシング | DC | 1.003 | Original | | HDR-0104 | |
| Sonic Shuffle ソニックシャッフル | DC | 1.001 | Original | | HDR-0125 | |
| Saka Tsuku Tokudai-gou: J.League Pro Soccer Club o Tsukurou! サカつく特大号 J.LEAGUE プロサッカークラブをつくろう! | DC | 1.003 | Original | | HDR-0126 | |
| Samba de Amigo Ver. 2000 | DC | 1.001 | Original | | HDR-0131 | |
| Sakura Taisen 3: Paris wa Moeteiru ka: Sakura Taisen 3 Movie Disc サクラ大戦3 ~巴里は燃えているか~ サクラ大戦3 ムービーディスク | DC | 1.002 | Original | | HDR-0136 | |
| Sakura Taisen Kinematron Hanagumi Mail サクラ大戦 キネマトロン 花組メール | DC | 1.008 | Original | | HDR-0136 | |
| Sega Extreme Sports セガ エクストリーム スポーツ | DC | 1.003 | Original | | HDR-0146 | |
| Sports Jam スポーツ・ジャム | DC | 1.005 | Original | | HDR-0153 | |
| SGGG: Segagaga セガガガ | DC | 2.000 | Tentou-ban | | HDR-0171 | |
| Sakura Taisen Online: Teito no Nagai Hibi サクラ大戦オンライン ~帝都の長い日々~ | DC | 1.007 | Original | | HDR-0184 | |
| Sakura Taisen Online: Paris no Yuuga na Hibi サクラ大戦オンライン ~巴里の優雅な日々~ | DC | 1.007 | Original | | HDR-0185 | |
| Space Channel 5 Part 2 スペース・チャンネル5 パート2 | DC | 2.000 | Original | | HDR-0190 | |
| Sakura Taisen (Disc 2) サクラ大戦 | DC | 1.010 | Sakura Wars Complete Box | | HDR-0201 | |
| Softkey Home/Family Bundle | PC | | Original | | HFB344CB-CD | |
| The Smurfs | PC | | 2nd Edition | | HFSMURPC52FGDEIP/A | |
| Stormovik: SU-25 Soviet Attack Fighter Stormovik | PC | | Hit Squad / Euro Power Pack | | HITDANCD001 | |
| Shuttle: The Space Flight Simulator Shuttle | PC | 1.01 | Hit Squad / Euro Power Pack | | HITDANCD015 | |
| Soft de Hard na Monogatari 2 ソフトでハードな物語2 | FMT | | Original | | HMA-214 | |
| Shijou Saikyou no Video Bible: The Greatest Video Bible in the World 史上最強のビデオバイブル | FMT | | Original | | HMA-251 | |
| Suikoden: Tenmei no Chikai 水滸伝・天命の誓い | FMT | | with Soundware | | HMB-108 | |
| Shooting Towns シューティング・タウンズ | FMT | | Original | | HMB-118 | |
| SimCity シム・シティ | FMT | Rev A | FM Towns Soft Collection Kaigai-hen Vol. 6 | | HMB-121A | |
| Sangokushi II 三國志Ⅱ | FMT | | with Soundware | | HMB-159 | |
| Sim Sports Diving: Soreyuke! Diving それゆけ!ダイイビング | FMT | | Original | | HMB-161 | |
| Shanghai 上海 | FMT | | Original | | HMB-192 | |
| Shougaku Ongaku (5·6-nensei-you) 小学音楽(5·6年生用) | FMT | Rev A | Original | | HMB-512A | |
| Shiki o Irodoru: Nihon no Shouka: Haru 四季を彩る 日本の唱歌 春 | FMT | | Original | | HMC-101 | |
| Shiki o Irodoru: Nihon no Shouka: Natsu 四季を彩る 日本の唱歌 夏 | FMT | | Original | | HMC-102 | |
| Shiki o Irodoru: Nihon no Shouka: Aki 四季を彩る 日本の唱歌 秋 | FMT | | Original | | HMC-103 | |
| Shiki o Irodoru: Nihon no Shouka: Fuyu 四季を彩る 日本の唱歌 冬 | FMT | | Original | | HMC-104 | |
| Software Contest Nyuusen Sakuhinshuu 1 ソフトウェア・コンテスト 入選作品集 1 | FMT | Rev A | Original | | HMC-139A | |
| Silent Möbius: Case: Titanic サイレント・メビウス | FMT | | Original | | HMC-143 | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | FMT | Rev 1 | Original | | HMC-157 | |
| Schwarzschild シュヴァルツシルト | FMT | | Original | | HMC-171 | |
| Super Shanghai: Dragon's Eye スーパー上海 ~ドラゴンズ・アイ ~ | FMT | | Original | | HMC-181 | |
| Super Collection 1: Game Technopolis (Himitsu no Hanazono & Kimi dake ni Ai o... +) スーパー・コレクション① (秘密の花園&キミだけに愛を…+) | FMT | | Original | | HMD-134 | |
| Splatterhouse スプラッターハウス | FMT | | Ving Vol. 13 | | HMD-146 | |
| Shuukan Shounen Magazine History 週刊少年マガジンヒストリー | FMT | 1.0 | Original | | HMD-151 | |
| The Secret of Monkey Island モンキー・アイランド | FMT | | Original | | HMD-155 | |
| Suzaku | FMT | | Original | | HMD-178 | |
| Steepia スティーピア | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 25 | | HMD-179 | |
| Sargon V: World Class Chess サルゴンⅤ | FMT | | Original | | HMD-191 | |
| Speech Trainer V1.0 L10 スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Strike Commander ストライク・コマンダー | FMT | | Original | | HMDC-1915 | |
| Super Real Mahjong PII & PIII+ スーパーリアル麻雀 PⅡ&PⅢ+ | FMT | | Ving Marty Taiou Vol. 1 | | HME-111 | |
| Steepia Lite スティーピア ライト | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 34 | | HME-118 | |
| Shinc | FMT | | Original | | HME-131 | |
| Secre Volume I: Naoko Iijima SECRE VOLUME ① 「飯島 直子」 | FMT | | Original | | HME-168 | |
| Super Collection 2: Game Technopolis (IV: Tesera & Hatsukoi Monogatari +) スーパー・コレクション② (Ⅳ~テセラ~&初恋物語+) | FMT | | Original | | HME-184 | |
| Secre Volume 3: Fumie Hosokawa SECRE VOLUME ③ 「細川 ふみえ」 | FMT | | Original | | HME-191 | |
| Secre Volume 4: Hitomi Fujisaki SECRE VOLUME ④ 「藤崎 仁美」 | FMT | | Original | | HME-196 | |
| Software Contest Nyuusen Sakuhinshuu 3 ソフトウェア・コンテスト 入選作品集 3 | FMT | | Original | | HME-200 | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Volume 6: Reiko Kato SECRE VOLUME ⑥ 「かとう れいこ」 | FMT | | Original | | HME-205 | |
| Secre Volume 7: Reiko Chiba SECRE VOLUME ⑦ 「千葉 麗子」 | FMT | | Original | | HME-209 | |
| Scavenger 4 スカベンジャー4 | FMT | Rev A | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217A | |
| Shangrlia 2 シャングリラ2 | FMT | | Original | | HME-220 | |
| Schwarzschild IV: The Cradle End シュヴァルツシルトⅣ -THE CRADLE END- | FMT | | Original | | HME-223 | |
| Sid Meier's Railroad Tycoon レイルロード・タイクーン デラックス | FMT | | Original | | HME-245 | |
| Scavenger 4 スカベンジャー4 | FMT | | Demo-ban | | HME-918 | |
| Secre Demo Disk | FMT | | Hibaihin | | HME-921 | |
| Super Real Mahjong PIV スーパーリ・アル麻雀PⅣ | FMT | | Ving Marty Taiou Vol. 7 | | HMF-138 | |
| Syndicate シンジケート | FMT | | Original | | HMF-163 | |
| SimFarm シムファーム | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 48 | | HMF-170 | |
| Sayaka + Miho 沙也香/美穂 | FMT | | Original | | HMF-179 | |
| SimCity 2000 シム・シティ2000 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 52 | | HMF-191 | |
| SimFarm: SimCity's Country Cousin シムファーム | FMT | | Demo | | HMF-920 | |
| Star Soldier for Palm OS スターソルジャー for Palm OS | PALM | | Original | | HMGOT060015 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 1) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 2) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Starry Sky: After Summer Portable: Etsuran Shite Please: Etsu Plea 2 Starry☆Sky ~After Summer~ Portable 閲覧してプリーズ"えつぷりっ2" | PSP | 1.01 | Shokai Genteiban | | HONEY-006, … | |
| Starry Sky: After Autumn Portable: Etsuran Shite Please: Etsu Plea 2 Starry☆Sky ~After Autumn~ Portable 閲覧してプリーズ"えつぷりっ2" | PSP | 1.00 | Shokai Genteiban | | HONEY-007, … | |
| Starry Sky: After Winter Portable Starry★Sky ~スタ・スカ~ ~After Winter~ Portable | PSP | 1.01 | Shokai Genteiban | | HONEY-008, … | |
| Starry Sky: After Winter Portable: Etsuran Shite Please: Etsu Plea 2 Starry★Sky ~スタ・スカ~ ~After Winter~ Portable 閲覧してプリーズ"えつぷりっ2" | PSP | 1.00 | Shokai Genteiban | | HONEY-008, … | |
| System Catalog: Kigyou-muke System no Goannai System Catalog 企業向けシステムのご案内 | 3DO | | Hibaihin | | HOU-013DO01 | |
| SegaSaturn Electronic Book Operator セガサターン 電子ブック・オペレーター | SS | 1.00C | Original | | HSS-0120 | |
| SegaSaturn Photo CD Operator セガサターン フォトCDオペレーター | SS | 1.007 | Original | | HSS-0121 | |
| SegaSaturn FDD Operator セガサターン FDDオペレーター | SS | 1.003 | Bundled with SegaSaturn FDD | | HSS-0128 | |
| Sports Island Freedom | XBOX360 | | Original | | HU-2015 | |
| Shinma Kourin 神魔降臨 | PC | | Original | | ICCD-005 | |
| Silicon Scream シリコンスクリーム | PC | | Original | | ID NO.9430-17-01 | |
| Schwarzschild GXR: Toki no Tsukaibito シュヴァルツシルトGXR 時現の遣人 | PC | | Original | | ID NO.9674-68-01 | |
| Sentimental Graffiti (Disc 1) センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01A | |