Region | Title | System | Version | Edition | Languages | Serial | Status |
| The Suffering | XBOX | | Original | | MW-021 | |
| The Suffering | XBOX | | Original | | MW-021 | |
| The Suffering | XBOX | | Original | | MW-021 | |
| The Suffering: Ties That Bind | XBOX | | Original | | MW-044 | |
| The Suffering: Ties That Bind | XBOX | | Original | | MW-044 | |
| The Suffering: Ties That Bind | XBOX | | Original | | MW-044 | |
| Super Bubble Pop | XBOX | | Original | | JA-004 | |
| Super Bubble Pop | XBOX | | Original | | JA-004 | |
| Super Monkey Ball Deluxe スーパーモンキーボール デラックス | XBOX | | Original | | SE-056 | |
| Super Monkey Ball Deluxe | XBOX | | Original | | SE-056 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman: The Man of Steel | XBOX | | Original | | IG-022 | |
| SWAT: Global Strike Team | XBOX | | Original | | VV-037 | |
| SWAT: Global Strike Team | XBOX | | Original | | VV-037 | |
| SWAT: Global Strike Team | XBOX | | Original | | VV-037 | |
| SX Superstar | XBOX | | Original | | AC-016 | |
| SX Superstar | XBOX | | Original | | AC-016 | |
| Syberia II | XBOX | | Original | | MI-008 | |
| Sega GT Online | XBOX | | Beta | | | |
| Spartan: Total Warrior | XBOX | | Review | | | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Sacred 2: Fallen Angel | XBOX360 | | Original | | KM-2001 | |
| Sacred 2: Fallen Angel セイクリッド2 | XBOX360 | | Platinum Collection | | SD-2047 | |
| Saints Row | XBOX360 | | Classics | | TQ-2001 | |
| Saints Row | XBOX360 | | Demo | | IM-2024 | |
| Saints Row セインツ・ロウ | XBOX360 | | Original | | TQ-2040 | |
| Saints Row 2 | XBOX360 | | Original | | TQ-2102 | |
| Saints Row 2 セインツ・ロウ2 | XBOX360 | | Original | | TQ-2044 | |
| Saints Row 2 세인츠 로우 2 | XBOX360 | | Original | | TQ-2044 | |
| Saints Row 2 | XBOX360 | | Original | | TQ-2044 | |
| Saints Row IV: Ultra Super Ultimate Deluxe Edition セインツロウ フォー ウルトラ・スーパー・アルティメット・デラックス・エディション | XBOX360 | | Original | | KM-2038 | |
| Saints Row: The Third: The Full Package (Disc 1) (DLC Installer) | XBOX360 | | Original | | TQ-2213 | |
| Sakura Flamingo Archives サクラフラミンゴアーカイヴス | XBOX360 | | Original | | NQ-2002 | |
| Samurai Dou 3 侍道3 | XBOX360 | | Original | | SD-2044 | |
| Samurai Shodown Sen | XBOX360 | | Original | | SN-2005 | |
| Samurai Warriors 2: Empires | XBOX360 | | Original | | KO-2006 | |
| Saw | XBOX360 | | Original | | KN-2050 | |
| Saw | XBOX360 | | Original | | KN-2050 | |
| Saw | XBOX360 | | Original | | KN-2050 | |
| Saw II: Flesh & Blood | XBOX360 | | Original | | KN-2082 | |
| SBK 08: Superbike World Championship | XBOX360 | | Original | | LS-2001 | |
| SBK 09: Superbike World Championship | XBOX360 | | Original | | LS-2004 | |
| SBK 2011: FIM Superbike World Championship | XBOX360 | | Original | | LS-2021 | |
| SBK Generations | XBOX360 | | Original | | LS-2033 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK: Superbike World Championship | XBOX360 | | Original | | CN-2005 | |
| Scene It? Box Office Smash! Scene It? Campione d'Incassi: Nuovissimi filmati e quiz sul cinema | XBOX360 | | Original | | MS-2144 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2038 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2037 | |
| Scene It? Ciak! Si Gira! Scene It? Ciak! Si Gira! Nuovissime domande e curiosità sul mondo del cinema | XBOX360 | | Original | | WR-2044 | |
| Scene It? Estrellas en la Pantalla Gigante | XBOX360 | | Original | | WR-2041 | |
| Scene It? Ganz großes Kino! | XBOX360 | | Original | | WR-2040 | |
| Scene It? Grandes Éxitos de Taquilla | XBOX360 | | Original | | MS-2144 | |
| Scene It? Kinohits | XBOX360 | | Bundled with 4 Controllers | | MS-2144 | |
| A Scene It? Lights, Cameraction | XBOX360 | | Original | | MS-2098 | |
| A Scene It? Lights, Cameraction! A Scene It? Luci, Camerazione! Il gioco a quiz sul cinema | XBOX360 | | Original | | MS-2098 | |
| Scene It? Luces, Cámara, ¡Acción! Scene It? Bright Lights! Big Screen! | XBOX360 | | Bundled with 4 Controllers | | MS-2098 | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Sega Rally Revo セガラリー レヴォ | XBOX360 | | Original | | SE-2022 | |
| Sengoku Musou 2 戦国無双2 | XBOX360 | | Original | | KO-2005 | |
| Sengoku Musou 2 with Moushouden 戦国無双2 with 猛将伝 | XBOX360 | | Original | | KO-2005 | |
| Sengoku-hime 2: Senran no Yo, Gunyuu Arashi no Gotoku 戦極姫2 ~戦乱の世、群雄嵐の如く~ | XBOX360 | | Original | | SY-2002 | |
| Senkou no Ronde Duo 旋光の輪舞DUO | XBOX360 | | Limited Edition | | GR-2041 | |
| The Serious Sam Collection | XBOX360 | | Original | | MK-2010 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| Serious Sam HD | XBOX360 | | Promo | | MK-2004 | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadows of the Damned シャドウ オブ ザ ダムド | XBOX360 | | Original | | EA-2346 | |
| Sharin no Kuni, Himawari no Shoujo 車輪の国、向日葵の少女 | XBOX360 | | Limited Edition | | FV-2017 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Snowboarding | XBOX360 | | Promo | | US-2078 | |
| Shaun White Snowboarding | XBOX360 | | Original | | US-2078 | |
| Shaun White Snowboarding | XBOX360 | | Target Limited Edition | | US-2078 | |
| Sherlock Holmes Versus Jack the Ripper | XBOX360 | | Original | | FE-2003 | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | XBOX360 | | Original | | JW-2003 | |
| Sherlock Holmes: Crimes & Punishments | XBOX360 | | Original | | FE-2015 | |
| Shiei No Sona-nyl Refrain: What a Beautiful Memories 紫影のソナーニル Refrain -What a beautiful memories- | XBOX360 | | Original | | T4-2001 | |
| Shikigami no Shiro III 式神の城Ⅲ | XBOX360 | | Original | | AW-2002 | |
| Shin Hokuto Musou 真・北斗無双 | XBOX360 | | Original | | KO-2047 | |
| Shin Sangoku Musou 4: Empires 真・三國無雙4 Empires | XBOX360 | | Original | | KO-2003 | |
| Shin Sangoku Musou 5: Empires 真・三國無雙5 Empires | XBOX360 | | Original | | KO-2023 | |
| Shin Sangoku Musou 5: Empires 真・三國無双5 Empires | XBOX360 | | Original | | KO-2023 | |
| Shooting Love. 10-shuunen: XIIZeal & DeltaZeal シューティングラブ。10周年 ~XIIZEAL & ΔZEAL~ スペシャルパック | XBOX360 | | Special Pack | | 3H-2002 | |
| Shooting Love. 200X シューティング ラブ。200X | XBOX360 | | Original | | TG-2001 | |
| Shutokou Battle X 首都高バトルX | XBOX360 | | Original | | GE-2001 | |
| Sid Meier's Civilization Revolution | XBOX360 | | Original | | TT-2021 | |
| Sid Meier's Civilization Revolution シヴィライゼーション レボリューション | XBOX360 | | Original | | TT-2117 | |
| Silent Hill: Homecoming | XBOX360 | | Original | | KN-2021 | |
| Les Simpson: Le Jeu | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| Die Simpsons: Das Spiel | XBOX360 | | Original | | EA-2057 | |
| Singularity | XBOX360 | | Original | | AV-2031 | |
| Singularity シンキュラリティ | XBOX360 | | Original | | AV-2198 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Skate. | XBOX360 | | Original | | EA-2067 | |
| Ski-Doo Snowmobile Challenge | XBOX360 | | Original | | VG-2001 | |
| Skylanders: Imaginators | XBOX360 | | | | AV-2352 | |
| Skylanders: Imaginators | XBOX360 | | Original | | AV-2352 | |
| Skylanders: Spyro's Adventure | XBOX360 | | Not for Resale | | AV-2219 | |
| Skylanders: SuperChargers | XBOX360 | | Starter Pack | | AV-2335 | |
| Skylanders: SuperChargers | XBOX360 | | Starter Pack | | AV-2335 | |
| Skylanders: SuperChargers | XBOX360 | | Original | | AV-2335 | |
| Skylanders: Swap Force | XBOX360 | | Starter Pack | | AV-2281 | |
| Skylanders: Swap Force | XBOX360 | | Original | | AV-2281 | |
| Skylanders: Swap Force | XBOX360 | | Starter Pack | | AV-2281 | |
| Skylanders: Trap Team | XBOX360 | | Starter Pack | | AV-2321 | |
| Skylanders: Trap Team | XBOX360 | | Original | | AV-2321 | |
| Skylanders: Trap Team | XBOX360 | | Starter Pack | | AV-2321 | |
| Skylanders: Trap Team | XBOX360 | | Original | | AV-2321 | |
| Skylanders: Trap Team | XBOX360 | | Original | | AV-2321 | |
| Sleeping Dogs | XBOX360 | | Original | | SQ-2065 | |
| Sleeping Dogs | XBOX360 | | Original | | SQ-2065 | |
| Sleeping Dogs | XBOX360 | | Original | | SQ-2073 | |
| Sleeping Dogs | XBOX360 | | Original | | SQ-2065 | |
| The Smurfs 2 | XBOX360 | | Original | | US-2237 | |
| Sniper Elite III | XBOX360 | | Original | | FO-2051 | |
| Sniper Elite V2 | XBOX360 | | Original | | FO-2024 | |
| Sniper: Ghost Warrior | XBOX360 | | Original | | CY-2001 | |
| De Snipers: Invisible, Silentadly | XBOX360 | | Original | | W6-2002 | |
| Snoopy's Grand Adventure | XBOX360 | | Original | | AV-2338 | |
| Soldier of Fortune: Payback | XBOX360 | | Original | | AV-2072 | |
| Soldier of Fortune: Payback | XBOX360 | | Original | | AV-2050 | |
| Sonic & Sega All-Stars Racing with Banjo-Kazooie | XBOX360 | | Original | | SE-2069 | |
| Sonic the Hedgehog ソニック・ザ・ヘッジホッグ | XBOX360 | | Original | | SE-2006 | |
| Sonic Unleashed | XBOX360 | | Original, Platinum Hits | | SE-2066 | |
| Sonic World Adventure ソニック ワールドアドベンチャー | XBOX360 | | Original | | SE-2066 | |
| Sonic's Ultimate Genesis Collection | XBOX360 | | Platinum Hits | | SE-2064 | |
| South Park: Der Stab der Wahrheit | XBOX360 | | Original | | US-2245 | |
| South Park: The Stick of Truth | XBOX360 | | Original | | US-2245 | |
| South Park: The Stick of Truth South Park: Палка Истины | XBOX360 | | Classics | | US-2245 | |
| Space Chimps | XBOX360 | | Original | | BT-2004 | |
| Space Chimps | XBOX360 | | Original | | BT-2004 Version: 1. | |
| Spectral Force 3 | XBOX360 | | Original | | AT-2003 | |
| Spectral Force 3: Innocent Rage スペクトラルフォース3 ~イノセント レイジ~ | XBOX360 | | Original | | IF-2001 | |
| Spectral Force 3: Innocent Rage | XBOX360 | | Original | | IF-2001 | |
| Spider-Man 3 | XBOX360 | | Original | | AV-2018 | |
| Spider-Man: Friend or Foe | XBOX360 | | Original | | AV-2042 | |
| Spider-Man: Friend or Foe | XBOX360 | | Original | | AV-2042 | |
| Spider-Man: Web of Shadows | XBOX360 | | Original | | AV-2069 | |
| Spider-Man: Web of Shadows | XBOX360 | | Original | | AV-2069 | |
| The Spiderwick Chronicles | XBOX360 | | Bundled with Audiobook | | VU-2022 | |
| Split/Second Split/Second: Velocity | XBOX360 | | Original | | BV-2023 | |
| Split/Second: Velocity | XBOX360 | | Original | | BV-2023 | |
| Sports Island Freedom | XBOX360 | | Original | | HU-2015 | |
| Star Ocean: The Last Hope (Disc 2) | XBOX360 | | Original | | SQ-2013 | |
| Star Ocean: The Last Hope (Disc 1) スターオーシャン4 -THE LAST HOPE- | XBOX360 | | Original | | SQ-2013 | |
| Star Ocean: The Last Hope (Disc 2) スターオーシャン4 -THE LAST HOPE- | XBOX360 | | Original | | SQ-2013 | |
| Star Ocean: The Last Hope (Disc 3) スターオーシャン4 -THE LAST HOPE- | XBOX360 | | Original | | SQ-2013 | |
| Star Trek | XBOX360 | | Original | | NM-2139 | |
| Steins;Gate 命運石之門 | XBOX360 | | Original | | FV-2008 | |
| Steins;Gate: Senkei Kousoku no Phenogram STEINS;GATE 線形拘束のフェノグラム | XBOX360 | | Limited Edition | | FV-2035 | |
| Stoked | XBOX360 | | Original | | DE-2003 | |
| Stoked ストークト | XBOX360 | | Original | | DE-2003 | |
| Stoked | XBOX360 | | Original | | DE-2003 | |
| Stoked: Big Air Edition | XBOX360 | | Original | | DE-2005 | |
| Stoked: Big Air Edition | XBOX360 | | Original | | DE-2005 | |
| Stormrise | XBOX360 | | Original | | SE-2054 | |
| Street Fighter IV: The Ties That Bind (Bonus Disc) | XBOX360 | | Xbox 360 Game Bundle | | CC-2033 | |
| Strike Witches: Hakugin no Tsubasa ストライクウィッチーズ -白銀の翼- | XBOX360 | | Original | | CF-2003 | |
| Stuntman: Ignition | XBOX360 | | Demo | | TQ-2069 | |
| Summer Athletics 2009 | XBOX360 | | Original | | DT-2006 | |
| Summer Athletics: The Ultimate Challenge | XBOX360 | | Original | | CV-2004 | |
| Summer Challenge: Athletics Tournament | XBOX360 | | Original | | RL-2014 | |
| Summer Stars 2012 | XBOX360 | | Original | | KM-2027 | |
| Super Robot Taisen XO スーパーロボット大戦XO | XBOX360 | | Original | | BP-2001 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superstars V8 Racing | XBOX360 | | Original | | LS-2003 | |
| Superstars V8: Next Challenge | XBOX360 | | Original | | LS-2008 | |
| Supreme Commander | XBOX360 | | Original | | AY-2005 | |
| Supreme Commander | XBOX360 | | Original | | AY-2001 | |
| Supreme Commander 2 スプリームコマンダー2 | XBOX360 | | Original | | SQ-2019 | |
| Surf's Up | XBOX360 | | Original | | US-2041 | |
| Surf's Up | XBOX360 | | Original | | US-2041 | |
| Shodai Xbox Game Gokansei Update Disc: 2007-nen 7-gatsuban 初代 Xbox ゲーム互換性アップデート ディスク (2007 年 7 月版) | XBOX360 | | Bundled with Halo History Pack | | | |
| The Sims 3: Pets | XBOX360 | | Beta | | | |
| The Sims 3: Pets | XBOX360 | | Beta | | | |
| Street Fighter X Tekken | XBOX360 | | Beta | | | |
| SAAR + AMOK PD CD-ROM Überarbeitete Version 12/93 | ACD | | Original | | | |
| SAAR AMOK II Oktober 1994 | ACD | | Original | | | |
| Samba World Cup | ACD | | Original | | | |
| The Scene Archive: 1988-1998 | ACD | | Original | | | |
| Scene Storm | ACD | | | | | |
| Scene Xplorer '97 Scene Explorer: From the Beginning into the Future | ACD | | Original | | | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| The Shadow of the Third Moon | ACD | 1.1 | Original | | | |
| Sid Meier's Civilization | ACD | | | | | |
| Sixth Sense Investigations | ACD | | Original | | | |
| Software 2000: Volume 1 (Disc 1) | ACD | | Original | | | |
| Software 2000: Volume 1 (Disc 2) | ACD | | Original | | | |
| Software Explosion | ACD | | | | | |
| Spielekiste 2 | ACD | | Original | | | |
| StormC 4 | ACD | 4 | Original | | | |
| The Strangers | ACD | | Original | | | |
| Street Racer | ACD | | | | | |
| Seek and Destroy Seek & Destroy | CD32 | | Original | | | |
| Sleepwalker | CD32 | | Original | | | |
| Soccer Kid | CD32 | | Original | | | |
| Sports: Football | CD32 | | | | | |
| Striker | CD32 | | Original | | | |
| Super Methane Bros. | CD32 | | Original | | | |
| Super Methane Bros. | CD32 | | Original | | | |
| Super Skidmarks | CD32 | 2.2 | Original | | | |
| Super Street Fighter II Turbo | CD32 | | Original | | | |
| Snoopy: The Case of the Missing Blanket | CDTV | | Original | | | |
| Sengoku Denshou 2 ~ Sengoku 2 戦国伝承2 | NGCD | | Original | | NGCD-040 | |
| Super Sidekicks: Tokuten-ou 得点王 | NGCD | | Original | | NGCD-052 | |
| Sangokushi IV 三國志Ⅳ | 3DO | | Original | | FZ-SJ2853 | |
| Scramble Cobra | 3DO | | Original | | FZ-SE0404 | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Original | | FZ-SJ0404 | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Demonstration-ban | | FZ-JJ9DSP-5G | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Scramble Cobra: Premium Version スクランブル・コブラ プレミアム・バージョン | 3DO | | Not for Sale | | FZ-JJ9PSC-5H | |
| Secre Fuumin no Omochabako セクレ・フーミンのおもちゃ箱 | 3DO | | Original | | FZ-SJ2651 | |
| Seimei Handan 姓名判断 | 3DO | | Original | | FZ-SJ4053 | |
| Sesame Street: Numbers セサミ・ストリート ~ナンバーズ~ | 3DO | | Original | | FZ-SJ1664 | |
| Shanghai: Banri no Choujou: The Great Wall 上海 ~万里の長城~ | 3DO | | Original | | FZ-SJ1660 | |
| Shock Wave 지구공습 2019 | 3DO | | Original | | GDT-GA 101 | |
| Shock Wave: Operation JumpGate ショック・ウェーブ ~オペレーション・ジャンプゲート~ | 3DO | | Demo-CD | | FZ-JJ9DSV-5D | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Slam 'n Jam '95 | 3DO | | Beta (CD-R) | | | |
| Slayer | 3DO | | Original | | | |
| SnowJob Starring Tracy Scoggins (Disc 1) | 3DO | | Original | | | |
| SnowJob Starring Tracy Scoggins (Disc 2) | 3DO | | Original | | | |
| Soccer Kid | 3DO | | Original | | | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Original | | FZ-SJ1661 | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Demo-ban | | FZ-JJ9DSS-4K | |
| Space Ace | 3DO | | Bundled with Magazine (Demo) | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Storage Manager: Memory Kanri Storage Manager メモリー管理 | 3DO | | Bundled with 3DO Memory Unit | | DFJN5018ZBZ | |
| Strahl シュトラール | 3DO | | Original | | FZ-SJ4651 | |
| The Super Model: Gail McKenna スーパー・モデル ゲイル・マッケンナ | 3DO | | Mihonban | | TPS-18012 | |
| Super Nova: Battery Navi バッテリー・ナビ | 3DO | | Hibaihin | | V1-9507 | |
| Super Real Mahjong P.V スーパーリアル麻雀PⅤ | 3DO | | Original | | S-3D951 | |
| Super Street Fighter II Turbo | 3DO | | Bundled with Magazine (4 Character Demo Disc) | | | |
| Super Wing Commander | 3DO | | Original | | R988DCXD | |
| Supreme Warrior (Disc 1) (Fire & Earth) サプリーム・ウォーリアー | 3DO | | Original | | | |
| Supreme Warrior (Disc 2) (Wind & Fang Tu) サプリーム・ウォーリアー | 3DO | | Original | | | |
| Sword & Sorcery ソード・アンド・ソーサリー | 3DO | | Demo-ban | | FZ-JJ9DSS-5H | |
| System Catalog: Kigyou-muke System no Goannai System Catalog 企業向けシステムのご案内 | 3DO | | Hibaihin | | HOU-013DO01 | |
| Shichi Sokusen 死地則戦 | PIPPIN | Rev A | Original | | BDS-20019 | |
| Sakura no Mori 櫻の杜 | FMT | | PC-9821 Release | | | |
| Samurai Spirits サムライ・スピリッツ | FMT | | Original | | JH-012 | |
| Sangokushi II 三國志Ⅱ | FMT | | with Soundware | | HMB-159 | |
| Sargon V: World Class Chess サルゴンⅤ | FMT | | Original | | HMD-191 | |
| Sayaka + Miho 沙也香/美穂 | FMT | | Original | | HMF-179 | |
| Sayonara no Mukougawa さよならの向こう側 | FMT | | Original | | CBF-0008 | |
| Scavenger 4 スカベンジャー4 | FMT | | Demo-ban | | HME-918 | |
| Scavenger 4 スカベンジャー4 | FMT | Rev A | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217A | |
| Scholar Movie Magazine Soukan-gou スコラ MOVIE MAGAZINE 創刊号 | FMT | | Original | | DWDC 4815 | |
| Schwarzschild シュヴァルツシルト | FMT | | Original | | HMC-171 | |
| Schwarzschild IV: The Cradle End シュヴァルツシルトⅣ -THE CRADLE END- | FMT | | Original | | HME-223 | |
| Secre Demo Disk | FMT | | Hibaihin | | HME-921 | |
| Secre Volume 3: Fumie Hosokawa SECRE VOLUME ③ 「細川 ふみえ」 | FMT | | Original | | HME-191 | |
| Secre Volume 4: Hitomi Fujisaki SECRE VOLUME ④ 「藤崎 仁美」 | FMT | | Original | | HME-196 | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Volume 6: Reiko Kato SECRE VOLUME ⑥ 「かとう れいこ」 | FMT | | Original | | HME-205 | |
| Secre Volume 7: Reiko Chiba SECRE VOLUME ⑦ 「千葉 麗子」 | FMT | | Original | | HME-209 | |
| Secre Volume I: Naoko Iijima SECRE VOLUME ① 「飯島 直子」 | FMT | | Original | | HME-168 | |
| The Secret of Monkey Island モンキー・アイランド | FMT | | Original | | HMD-155 | |
| Sexy in the Hawaii: Nice Gal Hawaii-hen Sexy in The Hawaii ~ナイス・ギャル ハワイ編~ | FMT | | Original | | | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | FMT | Rev 1 | Original | | HMC-157 | |
| Shanghai 上海 | FMT | | Original | | HMB-192 | |
| Shangrlia 2 シャングリラ2 | FMT | | Original | | HME-220 | |
| Shijou Saikyou no Video Bible: The Greatest Video Bible in the World 史上最強のビデオバイブル | FMT | | Original | | HMA-251 | |
| Shiki o Irodoru: Nihon no Shouka: Aki 四季を彩る 日本の唱歌 秋 | FMT | | Original | | HMC-103 | |
| Shiki o Irodoru: Nihon no Shouka: Fuyu 四季を彩る 日本の唱歌 冬 | FMT | | Original | | HMC-104 | |
| Shiki o Irodoru: Nihon no Shouka: Haru 四季を彩る 日本の唱歌 春 | FMT | | Original | | HMC-101 | |
| Shiki o Irodoru: Nihon no Shouka: Natsu 四季を彩る 日本の唱歌 夏 | FMT | | Original | | HMC-102 | |
| Shinc | FMT | | Original | | HME-131 | |
| Shinseiki Kouboushi: Dead Force 新世紀興亡史 デッド・フォース | FMT | | Original | | | |
| Shooting Towns シューティング・タウンズ | FMT | | Original | | HMB-118 | |
| Shougaku Ongaku (5·6-nensei-you) 小学音楽(5·6年生用) | FMT | Rev A | Original | | HMB-512A | |
| Shuukan Shounen Magazine History 週刊少年マガジンヒストリー | FMT | 1.0 | Original | | HMD-151 | |
| Sid Meier's Railroad Tycoon レイルロード・タイクーン デラックス | FMT | | Original | | HME-245 | |
| Silent Möbius: Case: Titanic サイレント・メビウス | FMT | | Original | | HMC-143 | |
| Sim Sports Diving: Soreyuke! Diving それゆけ!ダイイビング | FMT | | Original | | HMB-161 | |
| SimCity シム・シティ | FMT | Rev A | FM Towns Soft Collection Kaigai-hen Vol. 6 | | HMB-121A | |
| SimCity 2000 シム・シティ2000 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 52 | | HMF-191 | |
| SimFarm シムファーム | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 48 | | HMF-170 | |
| SimFarm: SimCity's Country Cousin シムファーム | FMT | | Demo | | HMF-920 | |
| Soft de Hard na Monogatari ソフトでハードな物語 | FMT | | Original | | | |
| Soft de Hard na Monogatari 2 ソフトでハードな物語2 | FMT | | Original | | HMA-214 | |
| Software Contest Nyuusen Sakuhinshuu 1 ソフトウェア・コンテスト 入選作品集 1 | FMT | Rev A | Original | | HMC-139A | |
| Software Contest Nyuusen Sakuhinshuu 3 ソフトウェア・コンテスト 入選作品集 3 | FMT | | Original | | HME-200 | |
| Soreike! Anpanman: Tanoshii Eigo Asobi それいけ! アンパンマン ~たのしいえいごあそび~ | FMT | | Original | | FMB-3010 | |
| Sotsugyou: Graduation '93 卒業’93 | FMT | | Original | | JH-002 | |
| Space Museum スペース・ミュージアム | FMT | | Original | | | |
| Special & Delicious! Original CD-ROM | FMT | | Bundled with Book | | TAIYOU-001 | |
| Speech Trainer V1.0 L10 スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Splatterhouse スプラッターハウス | FMT | | Ving Vol. 13 | | HMD-146 | |
| SSL Gallery Ver. 1 | FMT | | Original | | | |
| StarCruiser II for CD-ROM スタークルーザー Ⅱ for CD‐ROM | FMT | | Original | | JH-006 | |
| Steepia スティーピア | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 25 | | HMD-179 | |
| Steepia Lite スティーピア ライト | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 34 | | HME-118 | |
| Strike Commander ストライク・コマンダー | FMT | | Original | | HMDC-1915 | |
| Strike Commander Plus ストライク・コマンダーPLUS | FMT | | Original | | | |
| Suikoden: Tenmei no Chikai 水滸伝・天命の誓い | FMT | | with Soundware | | HMB-108 | |
| Super Collection 1: Game Technopolis (Himitsu no Hanazono & Kimi dake ni Ai o... +) スーパー・コレクション① (秘密の花園&キミだけに愛を…+) | FMT | | Original | | HMD-134 | |
| Super Collection 2: Game Technopolis (IV: Tesera & Hatsukoi Monogatari +) スーパー・コレクション② (Ⅳ~テセラ~&初恋物語+) | FMT | | Original | | HME-184 | |
| Super Real Mahjong PII & PIII+ スーパーリアル麻雀 PⅡ&PⅢ+ | FMT | | Ving Marty Taiou Vol. 1 | | HME-111 | |
| Super Real Mahjong PIV スーパーリ・アル麻雀PⅣ | FMT | | Ving Marty Taiou Vol. 7 | | HMF-138 | |
| Super Shanghai: Dragon's Eye スーパー上海 ~ドラゴンズ・アイ ~ | FMT | | Original | | HMC-181 | |
| Suzaku | FMT | | Original | | HMD-178 | |
| Syndicate シンジケート | FMT | | Original | | HMF-163 | |
| Scooby-Doo! | IXL | 1.0.0 | Original | | R9709 | |
| Safecracker | MAC | | Original | | | |
| Saikyou Kareshi: Dynamic Darling 最強彼氏 | MAC | | Original | | | |
| Sam & Max Hit the Road | MAC | | Original | | 8022133 | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| Sangokushi Eiketsuden 三國志英傑伝 | MAC | | Original | | KN10-82104 | |
| Sangokushi IV 三國志Ⅳ | MAC | | with Soundware | | KN10571070 | |
| Sanzennen Shokudou: Shoku Culture Simulation Game 三千年食堂 食カルチャーシミュレーションゲーム | MAC | | Original | | G012JAP-M | |
| Satsui no Shoumei: In the 1st Degree (Disc 1) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078A | |
| Satsui no Shoumei: In the 1st Degree (Disc 2) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078B | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 300202 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Schoolhouse Rock! Grammar Rock | MAC | | Original | | 9227 | |
| Scrabble: Crossword Game | MAC | 1.0.0.52 | Original | | P/N 10328-5 | |
| Le Secret du Templier | MAC | 1.0 | Covermount | | | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| Sexy PK: World Cup-ban セクシー・ピーケー ワールドカップ版 | MAC | | Original | | MMC-4065 | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Sherlock Holmes: Consulting Detective: Vol. III | MAC | 3.0 | | | CDRM 835400 | |
| Shrek 2 | MAC | | Original | | 10700-1CDA | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sid Meier's Colonization | MAC | | Original | | CLMC-60 | |
| A Silly Noisy House | MAC | | Original | | CDAC 014500 | |
| SimCity 2000: CD Collection | MAC | 1.20 | Original | | 1074-029-0601-A | |
| SimCity 3000 | MAC | 1.0.557 | Original | | 1500607 | |
| SimCity 4 (Disc 1) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 2) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity Enhanced CD-ROM | MAC | | MacPlay | | CD-MCR-041-0 | |
| The Sims 2: Pets (Expansion Pack) | MAC | | Original | | 11500-1CDA | |
| Les Sims: Superstar (Disc 1) (Disque Additionnel) | MAC | | Original | | | |
| Les Sims: Superstar (Disc 2) (Disque Additionnel) | MAC | | Original | | | |
| The Sims | MAC | | The Sims & The Sims: Livin' Large Expansion Pack | | | |
| The Sims | MAC | | | | | |
| The Sims | MAC | | | | | |
| The Sims: Hot Date (Expansion Pack) | MAC | | Original | | 10150-1CDA | |
| The Sims: Livin' Large (Expansion Pack) | MAC | | The Sims & The Sims: Livin' Large Expansion Pack | | | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | MAC | | Original | | 10430-1CDA | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | MAC | | Original | | 10430-2CDA | |
| The Sims: Vacation (Expansion Pack) | MAC | | Original | | | |
| SimTown: The Town You Build Yourself! シムタウン | MAC | | Original | | MMC-4093 | |
| Sin Gold SiN Gold | MAC | | Shooter Pack, MacPlay | | | |
| SiN Gold | MAC | | MacPlay | | | |
| SiN Gold | MAC | 1.1.1 | Original | | | |
| Sinkha | MAC | | Original | | | |
| The Software Toolworks Presents: Maniac Sports | MAC | | Original | | 2200820-590001 / I034100 | |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | MAC | | Original | | | |
| Solitaire Mania | MAC | | Original | | PART NO. 05SMM-01 | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | MAC | | Original | | S4330250Z12ZZ | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| Spectre VR CD | MAC | | Original | | | |
| Spider-Man | MAC | | Original | | | |
| Spycraft: The Great Game (Disc 1) | MAC | | Original | | CDM-3110-101-US | |
| Spycraft: The Great Game (Disc 2) | MAC | | Original | | CDM-3110-102-U3 | |
| Spycraft: The Great Game (Disc 3) | MAC | | Original | | CDM-3110-103-U3 | |
| Star Fighter | MAC | | | | 03239-001 | |
| Star Trek: Elite Force II (Disc 1) | MAC | | Original | | 10440-1CDA | |
| Star Trek: Elite Force II (Disc 2) | MAC | | Original | | 10440-2CDA | |
| Star Trek: New Worlds: Ad | MAC | | Art Assets | | | |
| Star Trek: Starfleet Academy (Disc 1) | MAC | 1.1 | Original | | CD-MCR-069-0 | |
| Star Trek: Starfleet Command II: Empires at War: Ad | MAC | | Art Assets | | | |
| Star Trek: The Next Generation: Klingon Honor Guard (Game Disk) | MAC | | Original | | P/N 04-17512CD1 | |
| Star Trek: The Next Generation: Klingon Honor Guard (Install Disk) | MAC | | Original | | P/N 04-17512CD2 | |
| Star Trek: Voyager: Elite Force | MAC | | Original | | | |
| Star Wars: Dark Forces | MAC | 1.00 | Original | | | |
| Star Wars: Dark Forces (Special Edition: 3 Playable Levels) | MAC | 1.2 | LucasArts Macintosh Archives Vol. I, The | | 8022134 | |
| Star Wars: Episode I: Racer | MAC | 1.0 | Original | | | |
| Star Wars: Jedi Knight II: Jedi Outcast | MAC | 1.03 | Original | | 10200-1CDA | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | MAC | 1.0.1 | Original | | 10610-1CDA | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 2) | MAC | 1.0.1 | Original | | 10610-2CDA | |
| Star Wars: Rebel Assault | MAC | | Original | | 634630 | |
| Star Wars: Rebel Assault | MAC | | Original | | 634630, CDRM1208410 | |
| Star Wars: Rebel Assault | MAC | | Demo | | CDRM1209730 | |
| Star Wars: Rebel Assault | MAC | 1.06 | LucasArts Macintosh Archives Vol. I, The | | 8022132 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | MAC | | Original | | | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | MAC | | Original | | | |
| Star Wars: Screen Entertainment | MAC | | Mac Game Bundle | | | |
| Star Wars: TIE Fighter: Collector's CD-ROM | MAC | 1.0 | Original | | 2062130 | |
| Star Wars: X-Wing: Collector's CD-ROM | MAC | 1.0 | Original | | 2052130 | |
| Star Wars: X-Wing: Collector's CD-ROM | MAC | 1.01 | Original | | 2052130 | |
| StarCraft | MAC | 1.05 | Original | | S0013318 | |
| StarCraft: Brood War (Expansion Set) | MAC | 1.05 | Original | | S0015019 | |
| Stellaluna | MAC | | Original | | 2069-1-01 | |
| Syndicate | MAC | | Original | | 7558 | |
| System Shock | MAC | | Original | | EA 568407 | |
| Sid Meier's Civilization III Complete | MAC | 1.22 | Original | | 11180-1DDA | |
| Sid Meier's Civilization IV: Beyond the Sword | MAC | | Original | | 12090-1DDA | |
| The Sims 2 | MAC | | Rerelease | | 10880-1DDA | |
| The Sims 2: Bon Voyage (Expansion Pack) | MAC | | Original | | 11780-1DDA | |
| The Sims 2: Nightlife (Expansion Pack) | MAC | | Original | | 11330-1DDA | |
| The Sims 2: Open for Business (Expansion Pack) | MAC | | Original | | 11392-1DDA | |
| The Sims 2: Open For Business (Expansion Pack) | MAC | | Original | | 11390-1DDA | |
| The Sims 2: University (Expansion Pack) | MAC | | Original | | 11110-1DDA | |
| The Sims: Complete Collection | MAC | 2.9.1 | Original | | 11370-1DDA | |
| The Sims: Party Pack | MAC | | Original | | 10790-1DDA | |
| Star Wars: Battlefront | MAC | 1.2 | Original | | 10900-1DDA | |
| Star Wars: Empire at War | MAC | 1.05 | Original | | 11490-1DDA | |
| Star Wars: Jedi Knight Gold Pack | MAC | | Original | | 12280-1DDA | |
| Star Wars: Knights of the Old Republic | MAC | 1.03 | Original | | 10660-1DDA | |
| Star Wars: Mac Pack | MAC | | Original | | 12300-1DDA | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | MAC | | Original | | 12240-1DDA | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | MAC | | Original | | 12240-1DDA2 | |
| Sälis Cirkus Äventyr | CDI | | Original | | 817 0011 | |
| Salvat Enciclopedia Interactiva | CDI | | Original | | B-44677-96 | |
| Salvat Enciclopedia Interactiva: Nueva Versión '98 | CDI | L.01.01 | Original | | | |
| Sandy's Circus Adventure | CDI | | Original | | 690 0222 | |
| Sandy's Circus Avontuur | CDI | | Original | | 814 0008 | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| Say What You Want | CDI | | Original | | | |
| Scan & Teach: Thema 1-6: Klasse 3 | CDI | | Original | | | |
| Scan & Teach: Thema 7-12: Klasse 3 | CDI | | Original | | | |
| Die Schöne und das Tier | CDI | | Original | | 813 0040 | |
| Les Schtroumpfs: Le Téléportaschtroumpf | CDI | | Original | | SCHTRFR4011 | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Seasons Greetings from Philips Media | CDI | | Original | | | |
| Secret Mission | CDI | | Original | | 810 0272 | |
| Secret Mission | CDI | 1.01 | Beta | | 810 0272 | |
| Secret Mission | CDI | 1.07 | Original | | 812 0053 | |
| Secret Mission | CDI | 1.06 | Original | | 813 0160 | |
| Secret Mission | CDI | | Original | | 814 0133 | |
| Self Selling Disc | CDI | 01 | Original | | | |
| Self Selling Disc | CDI | 3.1 | | | | |
| Self Selling Disc | CDI | 3.1 | | | 310-690-049-2 | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Serie Privélessen: Klassieke Gitaar: Handleiding voor Beginners | CDI | 1.06 | Original | | 814 0067 | |
| Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
| Sesame Street Kazu Asobi: A Visit to Sesame Street: Numbers セサミストリート かずあそび | CDI | | Original | | PCIM-00013 | |
| Sesame Street Moji Asobi: A Visit to Sesame Street: Letters セサミストリート もじあそび | CDI | | Original | | PCIM-00012 | |
| Shari Lewis Lamb Chop's Play-Along! Action Songs | CDI | | Original | | 310690289-2 | |
| Shorelines | CDI | | | | | |
| ShowMaster | CDI | 1.0 | Demo | | | |
| Si Balla! | CDI | 1.01 | Beta | | 815 0066 | |
| Si Balla! | CDI | 1.03 | Original | | 815 0066 | |
| Sieben Schritte zum Erfolg | CDI | | | | | |
| Sieben Schritte zum Erfolg II | CDI | | | | | |
| Silhouette: CD-i Demo Version | CDI | | Original | | | |
| Simulation Eikaiwa: CD-I Taiken America Ryokou シュミレーション英会話 CD-I体験アメリカ旅行 | CDI | | Original | | | |
| Sinnaneun Susjanala 2 신나는숫자나라 2 | CDI | | Original | | ISC 3008 | |
| Sipa Image: First Image Catalog on CD-I | CDI | | Original | | | |
| Skin Style | CDI | | Original | | | |
| Sliver (Disc 1) | CDI | | Original | | 310690309-2 | |
| Sliver (Disc 2) | CDI | | Original | | 310690309-2 | |
| Smilde | CDI | | Original | | | |
| Solar Crusade | CDI | | Original | | SOLARGB5511 | |
| Solitaire | CDI | | Prototype | | | |
| Somewhere: Une Envie de Naturel | CDI | | | | | |
| Somewhere: Une Envie de Naturel: Printemps 96 | CDI | | Original | | | |
| Soundtrap | CDI | 1.06 | Original | | 811 0032 | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Space Safari | CDI | 01.08 | Original | | 811 0035 | |
| Spine Sense: The Interactive Back Protection Program | CDI | | Original | | | |
| St. Petersbourg et les Trésors de l'Ermitage: The Art of the Czars | CDI | | Original | | 812 0056 | |
| Star Trek VI: Das unentdeckte Land (Disc 1) | CDI | 1.04 | Original | | 813 1023 | |
| Star Trek VI: Das unentdeckte Land (Disc 2) | CDI | 1.01 | Original | | 813 1024 | |
| Star Trek VI: The Undiscovered Country (Disc 1) | CDI | | Original | | 811 1007 | |
| Star Trek VI: The Undiscovered Country (Disc 1) | CDI | | Original | | 811 1007 | |
| Star Trek VI: The Undiscovered Country (Disc 2) | CDI | | Original | | 811 1007 | |
| Star Trek VI: The Undiscovered Country (Disc 2) | CDI | | Original | | 811 1007 | |
| Star Trek VI: The Undiscovered Country (Disc 1) | CDI | | Original | | 310690304-2 | |
| Star Trek VI: The Undiscovered Country (Disc 2) | CDI | | Original | | 310690304-2 | |
| Starring You: BZN Starring You: Zing Mee met Bekende Duetten van BZN | CDI | | Original | | 2700586 | |
| Stars on CD-i: Ad Peters | CDI | | Original | | | |
| Stars on CD-I: Rob Peetoom | CDI | | Original | | | |
| Stichting voor de Technische Wetenschappen: Jaarverslag 91 Technology Foundation: Annual Report 91 | CDI | | Original | | 2036.001 | |
| Sticks 'n' Fire: Stop That Train | CDI | | Original | | CMC 24020-2CD-I | |
| Stickybear Family Fun | CDI | | Original | | 810 0237 | |
| Stickybear Family Fun | CDI | | Original | | 310690258-2 | |
| Stickybear Preschool | CDI | 1.03 | Beta | | 690 2572 | |