| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Saishuu Densha
最終電車 体験版 | PSX | | Taikenban |  | SLPM-80215 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Sakura Taisen (Disc 1)
サクラ大戦 | SS | 1.005 | Original | | GS-9037 | |
| Sakura Taisen (Disc 1)
サクラ大戦 | SS | 1.005 | Original | | GS-9037 | |
| Sakura Taisen (Disc 2)
サクラ大戦 | SS | 1.005 | Original | | GS-9037 | |
| Sakura Taisen 2: Kimi, Shini Tamou Kotonakare (Disc 1)
サクラ大戦２ ～君、死にたもうことなかれ～ | SS | 1.002 | Shokai Tokutenban | | GS-9169 | |
| Sakura Taisen 2: Kimi, Shini Tamou Kotonakare (Disc 2)
サクラ大戦２ ～君、死にたもうことなかれ～ | SS | 1.002 | Shokai Tokutenban | | GS-9169 | |
| Sakura Taisen 2: Kimi, Shini Tamou Kotonakare (Disc 3)
サクラ大戦２ ～君、死にたもうことなかれ～ | SS | 1.002 | Shokai Tokutenban | | GS-9169 | |
| Sakura Taisen 4: Koi Se Yo Otome (Preview Disc)
サクラ大戦４ ～恋せよ乙女～ プレビュウＤｉｓｃ | DC | 1.001 | Original | | HDR-0184 | |
 | Santa Claus Saves the Earth | PSX | | Original |  | SLES-04023 | |
| Saru! Get You!
サルゲッチュ | PSX | 1.0 | Original | | SCPS-10091 | |
| SCEE Hits Demo | PS2 | 1.02 | |     | SCED-52970 | |
| Scorcher | SS | 3.004 | Original | | MK81214-50 | |
| Sega Extreme Sports | DC | 1.001 | Original | | MK-51081-50 | |
| Sega Flash Vol. 1 | SS | 1.001 | | | MK610-6288A | |
| Sega Flash Vol. 2 | SS | 1.000 | | | 610-6288B | |
| Sega Flash Vol. 3 | SS | 1.004 | | | 610-6288C | |
| Sega Flash Vol. 4 | SS | 1.003 | | | 610-6288D | |
| Sega Flash Vol. 5 | SS | 1.002 | | | 610-6288E | |
| Sega Flash Vol. 6 | SS | 1.000 | | | 610-6288F | |
| Sega Flash Vol. 7 | SS | 1.000 | | | MK610-6288G | |
| Sega Rally 2
セガラリー2 | DC | 1.04 | Original | | HDR-0010 | |
| Sega Rally Championship | SS | 1.000 | Original | | MK81207-50 | |
 | Sega Rally Championship | SS | 1.006 | Original | | 81207 | |
| Sega Saturn Preview Vol. 1 | SS | 1.000 | | | 610-6377 | |
| Sega Touring Car Championship | SS | 1.003 | Original | | MK81216-50 | |
| Sega Worldwide Soccer '98
セガ・ワールドワイド・サッカー’９８ | SS | 1.002 | Original | | GS-9187 | |
| Sega Worldwide Soccer 97 | SS | 1.000 | Original | | MK81112-50 | |
| Sega³ Demo | PS2 | 1.10 | | | SCED-50761 | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
 | Shadow Man | DC | 1.020 | Original | | T-8104D-18 | |
| Shadow Man: Rette deine Seele | PSX | | Original, Acclaimed Range | | SLES-02282 | |
| Shadow Master | PSX | | Demo | | SLED-00968 | |
| Shin Sangoku Musou 2
真・三國無双2 | PS2 | 1.30 | Original | | SLPM-65053 | |
| Shining Wisdom
シャイニング・ウィズダム | SS | 1.000 | Original | | GS-9057 | |
| Shinki Sekai Evolution
神機世界 エヴォリューション | DC | 1.023 | Original | | T-38701M | |
| Shinobi | PS2 | 1.00 | Demo | | SCED-51601 | |
| Sid Meier's Civilization: Shin Sekai Nanadai Bunmei
シヴィライゼーション 新・世界七大文明 | PSX | | Original | | SLPS-00336 | |
| Silent Hill | PSX | | Original, Platinum | | SLES-01514 … | |
| Silent Hill 2 | PS2 | 1.10 | The Silent Hill Collection, Special Edition | | SLES-50382 | |
| Silpheed | SCD | | Original | | MK-4423-50 | |
| Simple 1500 Series Vol. 12: The Quiz
SIMPLE1500シリーズ Vol.12 THE クイズ | PSX | 1.1 | Original | | SLPS-02448 | |
| Simple 1500 Series Vol. 26: The Tennis
SIMPLE1500シリーズ Vol.26 THE テニス | PSX | | Original | | SLPS-02228 | |
| Simple 1500 Series Vol. 65: The Golf
SIMPLE1500シリーズ Vol.65 THE ゴルフ | PSX | | Original | | SLPM-86842 | |
| SimSafari | PC | | Original, DICE | | | |
| Sky Target | SS | 1.000 | Original | | MK-81051-50 | |
| Solar Crusade | PC | 1.0 | Gold Games 2 | | | |
| Sonic Heroes | PS2 | 1.03 | Original, Platinum: The Best of PlayStation 2 | | SLES-51950 | |
| Soul Blade | PSX | | Original, Platinum | | SCES-00577 | |
| Soulcalibur II | PS2 | 1.00 | Demo | | SLED-51901 | |
| Soulcalibur II | GC | 1.00 | Original, Player's Choice | | DL-DOL-GRSE-USA | |
