Region | Title | System | Version | Edition | Languages | Serial | Status |
| E3 2004 Press Kit | PC | | Press Kit | | SEGA-E304-DO | |
| E3 2005 Product Information | PC | | Press Kit | | | |
| Earth 2140 | PC | 1.32 | Original | | | |
| Earth 2140: Gold | PC | 1.81 | Original | | HUN014 | |
| Earth 2150 (Disc 1) | PC | 2.8.7 | Original | | | |
| Earth 2150 (Disc 2) | PC | 2.8.7 | Original | | | |
| Earth 2150: Escape from the Blue Planet | PC | 2.8.7.1 | Back to Games | | CD 2642 | |
| Earth 2150: The Moon Project | PC | 1.3 | Original | | TWI018 | |
| Earth 2160 (Disc 1) | PC | 1.2 PL | Original | | | |
| Earth 2160 (Disc 2) | PC | 1.2 PL | Original | | | |
| Earth-Wind-Fire (Manuals, Demos and Goodies) -Earth·Wind·Fire- | PC | | Original | | 23491CD | |
| Easy Engels Easy Taalcursus Engels | PC | 5.1.0.0 | Original | | E07UK | |
| Ebola: Civilian Assault | PC | | Rerelease | | cd-027 | |
| Echelon | PC | 1.16.18r | Original | | | |
| Echelon | PC | 1.17.21r | Original | | | |
| Echelon: The Future of Flight Combat | PC | 1.16.20r | Original | | | |
| Economic War Ekonomi Savaşı | PC | | Original | | | |
| EEP: Vasutmodell Szimulator Program EEP 5.0 EEP: Vasútmodell Szimulátor Program EEP 5.0 | PC | 5.0 | Original | | | |
| Efi ve Indigo: Bakevot Hatz Hatzafon אפי ואינדיגו: בעקבות חץ הצפון | PC | | Original | | | |
| Egito 1156 A.C.: O Enigma da Tumba Real | PC | | Original | | | |
| Egypt III: The Fate of Ramses (Disc 1) | PC | 1.0.0 | Original | | EGT3HUCD1 | |
| Egypt III: The Fate of Ramses (Disc 3) | PC | 1.0.0 | Original | | EGT3HUCD3 | |
| Eisenwald: Blood of November Blood of November | PC | 1.3 | Original | | | |
| El Pato Paco: A First Look at Spanish | PC | 2.0 | Original | | 183384 | |
| The Elder Scrolls III: Morrowind: Zlota Edycja | PC | 1.6.1820 | eXtra Klasyka neXt | | | |
| The Elder Scrolls Online: Tamriel Unlimited (Disc 1) | PC | | Original | | TZB16048UND1 | |
| The Elder Scrolls Online: Tamriel Unlimited (Disc 2) | PC | | Original | | TZB16048UND2 | |
| The Elder Scrolls Online: Tamriel Unlimited (Disc 3) | PC | | Original | | TZB16048UND3 | |
| The Elder Scrolls Online: Tamriel Unlimited (Disc 4) | PC | | Original | | TZB16048UND4 | |
| The Elder Scrolls V: Skyrim: Legendary Edition | PC | 1.1 | The Elder Scrolls Anthology | | TZB0011899UND | |
| The Elder Scrolls: Chapter II: Daggerfall | PC | 1.2 | Original | | | |
| Elvis Presley | PC | | Original | | | |
| Empire Earth | PC | 1.00.2020 | BestSeller Series | | S1000032 | |
| Empire Earth เอ็มไพร์ เอิร์ธ | PC | 1.04.5188 | Original | | | |
| Empire Earth II (Disc 2) | PC | | Original, Best Seller Series | | S1002684, S1003816 | |
| Empire Earth II (Disc 1) | PC | 1.2 | Legjobb Választás (Gold Edition) | | S2165401 | |
| Empire Earth II (Disc 2) | PC | 1.2 | Legjobb Választás (Gold Edition) | | S2165402 | |
| Empire Earth II: The Art of Supremacy | PC | 1.0 | Legjobb Választás (Gold Edition) | | S2165403 | |
| Empire Earth: The Art of Conquest Expansion | PC | | Original | | | |
| Empire of Angels III 天使帝國Ⅲ | PC | | Original | | GC295 | |
| Empire: Total War (Disc 1) | PC | | Original, White Label, Total War Collection: Disc 1, Special Forces Edition | | 2546A, SEGA-PC083 | |
| Empire: Total War (Disc 2) | PC | | Original | | SEGA-PC083 | |
| End of Twilight End of Twilight: Zaginiona Tarcza Wikinga | PC | | Original | | | |
| End of Twilight 末日黎明 | PC | 1.0.0.1 | Original | | CR021 | |
| Ene Due Rabe | PC | | Original | | EXE CD ROM 015 | |
| The Engineer 2 | PC | | Ezt Vedd Meg! | | | |
| English ABC Inglés para Niños | PC | | Original | | | |
| English Dr.Kid 어린이 영어박사 | PC | | Original | | DGC3-0003 | |
| Enter the Matrix | PC | | eXtra Gra 9/07, eXtra Klasyka Next | | ETM DVD PL | |
| Enter the Matrix (Play Disc) | PC | 1.0.0.1 | Original, Collector's Edition | | IJKK-006-4, Part# 24394CD4 | |
| Enter the Matrix (Disc 1) | PC | 1.0.0.1 | Original, Collector's Edition | | IJKK-006-1, Part# 24394CD1 | |
| Enter the Matrix (Disc 2) | PC | 1.0.0.1 | Original, Collector's Edition | | IJKK-006-2, Part# 24394CD2 | |
| Enter the Matrix (Disc 3) | PC | 1.0.0.1 | Original, Collector's Edition | | IJKK-006-3, Part# 24394CD3 | |
| ER Скорая Помощь: в Борьбе за Жизнь | PC | | Original | | | |
| Escape from Monster Manor 악령의 성 | 3DO | | Original | | GDT-GA091 | |
| Escape the Lost Kingdom 3D: Ontrafel het Mysterie van de Vergeten Koning | PC | 11.5.0.593 | Collectors Edition | | MSL052135 | |
| Espinafres para a Criatividade | PC | | Original | | | |
| Europa Universalis | PC | 1.07c | Original, -Earth·Wind·Fire- | | 04-22388CD, 04-22388CDA | |
| Europa Universalis II | PC | 1.08 | Original | | ASEPA010-4 | |
| Europa Universalis II | PC | 1.01 | Original | | | |
| EverQuest (Disc 1) 无尽的任务 | PC | | PC Game Bundle | | | |
| EverQuest (Disc 2) 无尽的任务 | PC | | PC Game Bundle | | | |
| EverQuest: Bitmeyen Macera (Disc 1) | PC | | Original | | | |
| EverQuest: Bitmeyen Macera (Disc 2) | PC | | Original | | | |
| EverQuest: Bitmeyen Macera (Disc 3) | PC | | Original | | | |
| Evil Dead: Hail to the King (Disc 1) | PC | 1.0.0.0 | Original | | | |
| Evil Dead: Hail to the King (Disc 2) | PC | 1.0.0.0 | Original | | | |
| Evil Islands: Curse of the Lost Soul | PC | 1.06 | Original | | | |
| Evil Islands: Der Fluch der verlorenen Seele (Disc 1) Evil Islands: Curse of the Lost Soul | PC | 1.06 | Rerelease | | ROEVILISLA0001LAB1 | |
| Evil Islands: Der Fluch der verlorenen Seele (Disc 2) Evil Islands: Curse of the Lost Soul | PC | 1.06 | Rerelease | | ROEVILISLA0001LAB2 | |
| Evil Islands: Klątwa Zagubionej Duszy (Disc 1) | PC | 1.06 | Original | | | |
| Evil Islands: Klątwa Zagubionej Duszy (Disc 2) | PC | 1.06 | Original, Covermount | | | |
| Ex Machina (Disc 1) (Ustanovochnyj) | PC | 1.0 | Original | | | |
| Ex Machina (Disc 2) (Igrovoj) | PC | 1.0 | Original | | | |
| Extermination | PS2 | 1.00 | Original | | SCUS 97112 | |
| Extreme Pinball 梦幻弹子球 | PC | 1.0 | Original | | 7642, E3595CED | |