| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Small Soldiers | PSX | | Original |  | SLES-01582 |  |
 | Srpske Igre
Српске Игре | PC | | Original |  | SI_082004 | |
 | Sid Meier's Civilization II | PC | | Original |   | MPX91260DO1R | |
| SimCity 2000 | SS | 1.000 | Original | | MK81580-50 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | SimFarm
シムファーム | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 48 |  | HMF-170 | |
| Speech Trainer V1.0 L10
スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Sherlock Holmes: Consulting Detective | FMT | | Demonstration-ban | | HMC-901 | |
| Safecracker | PC | | Action-Games | | 80271 | |
 | Sol-Feace | MCD | RE | Bundled with Sega CD | | 4130 | |
| Syndicate Plus | PC | | Original |   | | |
| Syndicate Plus | PC | | Bundle Version OEM | | | |
| Supergames Volume 6 | PC | | Original | | | |
| Supergames Volume 10 | PC | | Original | | | |
 | Super Game: Visual CD Game | PC | | | | | |
 | The Suffering: Ties That Bind + Hello Kitty: Roller Rescue: Asset Disc | PC | | Press Kit | | | |
| Sudeki | PC | | Press Kit | | | |
 | Sub Culture
海底文明 | PC | 1.14 | Original | | | |
| Star Wars: Episode I: Disc #3: Covers | PC | | Press Kit | | | |
| Star Wars: Episode I: Cover Disk 4 | PC | | Press Kit | | | |
| The Star Scars
星の傷痕 【前編-空音-】 | PC | | Original | | | |
| Spyro: A Hero's Tail (Assets) | PC | | Press Kit | | | |
| Speed Freaks (Misc Artwork: PC-CD 2nd July '99) | PC | | Press Kit | | | |
| Space Marisar
スペースマリサー | PC | 1.00 | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Sonic Riders (Assets) | PC | | Press Kit | | | |
| Sonic P.R. Assets | PC | | Press Kit | | | |
| Solitaire | CDI | | Prototype | | | |
| Soldiers at War | PC | | Preview | | | |
 | The Soft Rock Games Collection CD | ARCH | | Original | | | |
| SMBX + Tak 2 Art | PC | | Press Kit | | | |
| Slam 'n Jam '95 | 3DO | | Beta (CD-R) | | | |
| SingStar: Media Materials: February 2004 | PC | | Press Kit | | | |
| Shining Soul II + Shining Force Assets
Shining Soul 2 + Shining Force Assets | PC | | Press Kit | | | |
| Shine Memories
シャインメモリーズ | PC | | Original | | | |
| Shenlong Shaonian
神龙少年 | PC | | Original |  | | |
| Shadow Vault: Demos and Materials | PC | | Original | | | |
| Seven Kingdoms: Artwork | MAC | | Art Assets | | | |
| Senpen Banka Hyaku Fushigi
千変挽歌百不思議 | PC | 20091230 | 2009 Winter W-pack | | | |
| Sega E3 Press Kit 2005
2005 E3 Press Kit | PC | | Press Kit | | | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| Saladman V9990
サラダマンＶ９９９０ | PC | 170908a | Original | | | |
| S.T.A.L.K.E.R.: Clear Sky (Assets) | PC | | Press Kit | | | |
