| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Spider-Man 2: Activity Center | PC | | Original |  | 31925.101.US |  |
| Spider-Man 2 | PC | | Demo | | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Spider-Man 2 | PC | | Demo | | | |
| Spider-Man 2 | PC | | Demo | | | |
 | Spider-Man 2
Человек-паук 2 | PC | | 1C: Kollekciya igrushek |  | | |
| Spider-Man (Disc 2) | PC | 1.0 | Original | | 32249.102.US | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| Spider-Man (Disc 1) | PC | 1.0 | Original | | 32249.101.US | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man | PC | | Original | | 31131.101.US | |
| Spider-Man
Spider-Man CD-ROM with PC Game | PC | | Demo | | | |
 | Spider-Man | PC | | Original, Essential Collection | | 31131.101.AU, 31131.101.UK | |
 | Spider-Man (Disc 2) | PC | | Original | | 32249.102.UK | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.UK | |
 | Spełnij Marzenia: Gra Piłkarska Pepsi | PC | | |  | | |
 | Speltajm: Djungelns kojigaste CD-ROM | PC | | Original |  | | |
| Speltajm: Djungelns kojigaste CD-ROM | PC | | Hemglass | | | |
 | Spelling Home Tutor | PC | | | | | |
| SpellForce: The Order of Dawn (Disc 2) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD2 v1.0 E, 28017-SM2 v1.0 F | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
 | Spellcross: L'Ultima Battaglia | PC | | CD-ROM Classic Collection 7 |  | | |
 | Spelen met Musti | PC | | Rerelease |  | PAS 00047 | |
 | Spelen met Bassie & Adriaan Deel 2 | PC | | Original | | 24.40334 | |
| Het Speelhuis van Muis | PC | | Original | | | |
| Speedway Championships | PC | | Original | | | |
| Speedster | PC | | Dice | | DCG 005813, DMM 005837 | |
| Speedlink Competition Pro USB: Sports Tournament Edition | PC | | Bundle Version Speedlink OEM |  | SL-6603-SPORTS-EU | |
| Speedboat Attack | PC | 0.9.9.0 | Budget |   | MMICDR 5097 | |
 | Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
 | Speed Mania
ｅ路狂飆 屏鵝公路篇 體驗版 | PC | | Demo |  | | |
| Speed Haste | PC | | Budget | | MMICDR 5078, MMICDR 5114 | |
 | Speed Demons | PC | | Original | | | |
 | Speed Demons | PC | | Covermount |  | | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Original | | Ref: 65702162 | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Busters | PC | 1.01 | Budget | | MMICDR 5706 | |
| Speed Busters
BGamer 045 (Disc 1) | PC | 1.01 | Focus Essential, Covermount | | ESS262 | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Specnaz: Antiterror. Missija na Balkanah (Disc 1)
Спецназ: Антитеррор. Миссия на Балканах | PC | | Original | | | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Special Forces: Nemesis Strike (Disc 3) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
 | Special Disk Tryset Mix 12 | PC | | Pre-Order Bonus |  | | |
| Spec Ops: Ranger Team Bravo | PC | | Original | | CD-RC010 | |
| Spec Ops: Ranger Assault | PC | | Złota Kolekcja Klasyki Komputerowej 2001 (Sold Out Software) | | IMG 064 | |
| Spec Ops: Platinum Collection (Disc 2) | PC | 1.0 | Original | | | |
| Spec Ops II: U.S. Army Green Berets | PC | | Budget, BIS Collezione CD-ROM | | 10019 | |
| Spec Ops II: U.S. Army Green Berets | PC | | Original | | | |
| Spaß am Turnierreiten
Equestriad 2001 | PC | | Original | | | |
 | Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| Spaceship Warlock
スペースシップ・ワーロック | PC | | Original | | NCCRM-0003 | |
| SpaceHaste
BGamer 070 (Disc 2) | PC | | Covermount | | | |
| SpaceChem | PC | 1012 | Limited Edition (Kickstarter) | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Space-Dude: Der Retter des Universums | PC | | Original | | | |
| Space Station Simulator | PC | 1.1 | Original | | | |
 | Space Station Simulator | PC | 1.0 | Original | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Space Station Manager
Космоград | PC | 1.2.1 Rus | Original | | | |
| Space Sniper Maya (Disc 2)
スペーススナイパー マヤ | PC | | Original | | GOR-0004 2/2 | |
| Space Sniper Maya (Disc 1)
スペーススナイパー マヤ | PC | | Original | | GOR-0004 1/2 | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
 | Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SoftKey, SierraOriginals | | CDRM SQU344AE-CD, S4840220012ZZ | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | CD 7011 SPI | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers
Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | | Original | | 832974330 | |
| Space Ofera Agga Ruter: Kyoufu no Uchuu Majo
Ｓｐａｃｅ Ｏｆｅｒａ アッガ・ルター 恐怖の宇宙魔女 | PC | | Original | | | |
| Space Marisar
スペースマリサー | PC | 1.00 | Original | | | |
| Space Marines: Der Stählerne Kaiser (Disc 2) | PC | 18.23 | Original, Classic Line | | | |
| Space Marines: Der Stählerne Kaiser (Disc 1) | PC | 18.23 | Original, Classic Line | | | |
| Space Marines: Der Stählerne Kaiser | PC | | All You Can Play: Adventure & Fantasy | | | |
| Space Mahjongg | PC | | Original | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Invaders: The Original Game
スペースインベーダー | PC | | Original | | | |
| Space Invaders: The Original Game
Space Invaders '95 | PC | | Original | | | |
| Space Invaders
スペースインベーダー | PC | | Yuuyuu 1,480-yen (Publishing Distribution) | | KMK-1210, MKY-055 | |
| Space Invada!! Type Shinai to Tama ga Denai.
ＳＰＡＣＥ ＩＮＶＡ打！！ ／ ＳＰＡＣＥ ＩＮＶＡＤＥＲＳ！！ タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Space in Motion: Future Trade | PC | 1.01 | Original | | | |
| Space Games: Direkt Starter Games | PC | | Original | | | |
| Space Empires V | PC | 1.0 | Original | | 902109CD | |
| Space Empires V
Космическая Империя V | PC | 1.66 | Original | | | |
| Space Empires V | PC | 1.30 | Covermount | | | |
| Space Empires V | PC | | Original | | EI-2171 ML03 | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Space Dynagon Kai
スペース大納言(改 | PC | | Original | | MSCD-0026 | |
| Space Dogs: Adventure to the Moon
Белка и Стрелка. Лунные приключения | PC | 1.0.0 | Original | | | |
| Space Clash | PC | | Original | | M-25324-1999 | |
| Space Clash
Space Clash: Das letzte Imperium | PC | | Original | | | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37218 | |
| Space Blaster
Swarm | PC | | Original | | | |
