Region | Title | System | Version | Edition | Languages | Serial | Status |
| SimTower: The Vertical Empire | PC | 1.0 | Original | | 1051-031-0601-A | |
| SimTown シムタウン | PC | 1.00 | Original | | WIC-5119 | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-B | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| SimTown: La città fai-da-te! | PC | | Original | | 05037-031-0601 | |
| SimTown: The Town You Build Yourself! シムタウン | MAC | | Original | | MMC-4093 | |
| SimTown: The Town You Build Yourself! | MAC | | Original | | 0037-000-0601-A, 0037-029-0601-A | |
| SimTunes | PC | | Original | | 0135-000-0601-A | |
| Simulation Eikaiwa: CD-I Taiken America Ryokou シュミレーション英会話 CD-I体験アメリカ旅行 | CDI | | Original | | | |
| Simulation Pro Yakyuu '99 シミュレーションプロ野球’99 | PSX | | Original | | SLPS 02102 | |
| Simulation RPG Tkool シミュレーションRPGツクール | PSX | | Original | | SLPS 00876 | |
| Simulation RPG Tkool シミュレーションRPGツクール | SS | 1.003 | Original | | T-2106G | |
| Simulation Zoo シミュレーションズー | PSX | | Original | | SLPS 00458 | |
| Simulation Zoo シミュレーション・ズー | SS | 1.001 | Original | | T-18611G | |
| Simulmondo Compilation 3 PC CD-ROM: Dylan Dog + Tex | PC | | Original | | | |
| SiN | PC | | Original | | 1000076.101.GM | |
| Sin & Punishment: Star Successor | WII | | Original | | RVL-R2VE-USA-B0 | |
| Sin and Punishment: Successor of the Skies | WII | | Original | | RVL-R2VP-EUR-B0 | |
| Sin Chawon Game Neptune V 신차원게임 넵튠 V | PS3 | 01.00 | Original | | BLKS 20417 | |
| Sin Combat Choro Q 신컴뱃 쵸로Q | PS2 | 1.00 | Original | | SLKA 25047 | |
| SiN Episodes: Emergence | PC | | Original | | VAEX7705155D | |
| SiN Episodes: Emergence | PC | 1.0.0.0 | Original | | VAI07705155D | |
| SiN Episodes: Emergence シン エマージェンス エピソード 1 | PC | | Original | | | |
| SiN Episodes: Emergence | PC | 2722 | Original | | | |
| SiN Episodes: Emergence | PC | | Original | | 984707 | |
| Sin Junghwa-daeseon: Michaelgwa Meimeiui Moheom 신중화대선 ~마이클과 메이메이의 모험~ | WII | | Original | | RVL-RTDK-KOR | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.UK | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.US | |
| Sinbad Adventure wa Enomoto Kanako de Dou desu ka シンドバッドアドベンチャーは榎本加奈子でどうですか | PS2 | 1.02 | Original | | SLPS 25420 | |
| Sincheon Magye: GOC IV: Another Side 신천마계 ~GOCⅣ 어나더 사이드~ | PSP | 1.00 | Original | | ULKS 46013 | |
| Sing!! Sega Game Music Presented by B. B. Queens | MCD | | Original | | BVRR-1 | |
| Singi Hwansang: SSII Unlimited Side 신기환상 ~SS II 언리미티드 사이드~ | PSP | 1.00 | Original | | ULKS-46094 | |
| Singles 2: Lyubov' vtroem Singles 2: Любовь втроем | PC | | Original | | | |
| Singles 2: Wilde Zeiten | PC | | Original | | ECD008010M | |
| SingStar | PS3 | 01.01 | Original | | BCES-00011 … | |
| SingStar Amped | PS2 | 1.01 | Original | | SCES-55159 … | |
| SingStar Amped | PS2 | 1.00 | Original | | SCUS-97612 | |
| SingStar e la Magia Disney | PS2 | 1.00 | Original | | SCES-55260 | |
| SingStar Made in Germany | PS2 | 1.00 | Original | | SCES-55564 | |
| SingStar Mallorca Party | PS3 | 01.02 | Original | | BCES-00519 | |
| SingStar Mallorca Party | PS3 | 02.00 | Original | | BCES-00519 … | |
| SingStar Mallorca Party | PS2 | 1.00 | Original | | SCES-55489 | |
| SingStar Mallorca Party | PS2 | 2.00 | Original | | SCES-55489 … | |
| SingStar Mecano | PS3 | 01.00 | Original | | BCES-00583 | |
| SingStar Mecano | PS2 | 1.00 | Original | | SCES-55540 | |
| SingStar MegaHits | PS3 | 01.00 | Original | | BCES-02043 | |
| SingStar Miliki | PS2 | 1.00 | Original | | SCES-55566 | |
| SingStar Morangos com Açúcar | PS3 | 01.01 | Original | | BCES-00518 | |
| SingStar Morangos com Açúcar | PS2 | 1.00 | Original | | SCES-55515 | |
| SingStar Motown | PS3 | 01.01 | Original | | BCES-00596 | |
| SingStar Motown | PS2 | 1.00 | Original | | SCES-55550 | |
| SingStar Motown | PS2 | 1.00 | Original | | SCES-55552 | |
| SingStar Motown | PS2 | 1.00 | Original | | SCES-55551 | |
| SingStar Motown | PS2 | 1.00 | Original | | SCES-55553 | |
| SingStar NRJ Music Tour | PS2 | 1.00 | Original | | SCES-52828 | |
| SingStar Rocks! with RTE 2fm | PS2 | 1.00 | Original | | SCES-54025 | |
| SingStar Sjung med Disney | PS2 | 1.00 | Original | | SCES-55261 | |
| SingStar Store Drømme | PS2 | 1.01 | Original | | SCES-55590 | |
| SingStar Summer Party | PS2 | 1.00 | Original | | SCES-55060 | |
| SingStar Summer Party | PS2 | 1.00 | Original | | SCES-55056 | |
| SingStar Summer Party | PS2 | 1.00 | Original | | SCES-55057 … | |
| SingStar Summer Party | PS2 | 1.00 | Original | | SCES-55127 | |
| SingStar Summer Party | PS2 | 1.01 | Original | | SCES-55128 | |
| SingStar SuomiBileet | PS3 | 01.00 | Original | | BCES-02044 | |
| SingStar SuomiHitit | PS3 | 01.00 | Original | | BCES-00847 | |
| SingStar SuomiHitit | PS2 | 1.00 | Original | | SCES-55612 | |
| SingStar SuomiHuiput | PS3 | 01.01 | Original | | BCES-01735 | |
| SingStar SuomiPop | PS2 | 1.00 | Original | | SCES-55521 | |
| SingStar SuomiRock | PS2 | 1.00 | Original | | SCES-55177 | |
| SingStar SuomiSuosikit | PS3 | 01.00 | Original | | BCES-01255 | |
| SingStar SuomiSuosikit | PS2 | 1.00 | Original | | SCES-55650 | |
| SingStar Syng med Disney | PS2 | 1.00 | Original | | SCES-55262 | |
| SingStar The Dome | PS2 | 1.00 | Original | | SCES-53180 … | |
| SingStar Ultimate Party SingStar Короли вечеринок | PS3 | 01.02 | Original | | BCES-02025 … | |
| SingStar Ultimate Party | PS3 | 01.00 | Original | | BCES-02042 | |
| SingStar Ultimate Party SingStar Mistrzowska Impreza | PS3 | 01.00 | Original | | BCES-02046 | |
| SingStar Vol. 2: Media Information | PC | | Original | | | |
| SingStar Wakacyjna Impreza! | PS2 | 1.00 | Original | | SCES-55061 | |
| SingStar Zingt met Disney | PS2 | 1.00 | Original | | SCES-55401 | |
| SingStar: Chansons Magiques de Disney | PS2 | 1.00 | Original | | SCES-55257 | |
| Singularity | PC | | Original | | 33309101GM | |
| Singularity シンギュラリティ | PS3 | 01.00 | Original | | BLJM 60220 | |
| Sink or Swim | PC | | Original | | | |
| Sinking Island: A Jack Norm Investigation | PC | | Original | | 16837EGA0074 | |
| Sins of a Solar Empire | PC | | Original | | | |
| Sins of a Solar Empire シンズ オブ ア ソーラーエンパイア | PC | | Original | | ZPG-0090 | |
| Sins of a Solar Empire | PC | 1.00 | Original | | | |
| Sipa Image: First Image Catalog on CD-I | CDI | | Original | | | |
| Sister Princess 2: Premium Fan Disc (Disc A) シスター・プリンセス2 プレミアムファンディスク | PSX | | Original | | SLPS 03556 | |
| Sister Princess 2: Premium Fan Disc (Disc B) シスター・プリンセス2 プレミアムファンディスク | PSX | | Original | | SLPS 03557 | |
| Sister Princess: Premium Edition (Disc 1) シスター・プリンセス プレミアム・エディション | DC | 1.003 | Original | | T-27802M | |
| Sister Princess: Premium Edition (Disc 2) シスター・プリンセス プレミアム・エディション | DC | 1.003 | Original | | T-27802M | |
| Sister's Secrecy: Mysteriöse Abstammung | PC | | Original | | | |
| Sizumanai Tsuki 沈マナイ月 | PC | | Original | | | |
| Skateboard Madness: Xtreme Edition | PS2 | 1.01 | Original | | SLES-54716 | |
| Ski Air Mix スキーエアーミックス | PSX | | Original | | SLPS 01476 | |
| Ski and Shoot | WII | | Original | | RVL-RUME-USA | |
| Ski Jumping 2005 | PC | 1.0 | Original | | 177025 | |
| Ski Jumping 2006 Чемпион Трамплина: Зимние Игры 2006 | PC | | Original | | | |
| Ski Jumping Pairs: Reloaded スキージャンプ・ペア リローデッド | PS2 | 1.10 | Original | | SLPS 25616 | |
| Ski Racing 2005 Ski Racing 2005 featuring Hermann Maier | XBOX | | Original | | JW-005 | |
| Ski Racing 2005 Ski Racing 2005 featuring Hermann Maier | PC | 1.0 | Original | | ROSKIRACING0000LAB | |
| Ski Racing 2006 Ski Racing 2006 featuring Hermann Maier | XBOX | | Original | | JW-010 | |
| Ski Region Simulator Ski Region Simulator 2012 | PC | 4.1.6.1 | Original | | | |
| Ski-Doo Snowmobile Challenge | PS3 | 01.06 | Original | | BLES-01486 | |
| Ski-Doo Snowmobile Challenge | WII | | Original | | RVL-R87E-USA-B0 | |
| Ski-Doo Snowmobile Challenge | XBOX360 | | Original | | VG-2001 | |
| Ski-Doo Snowmobile Challenge | PS3 | 01.04 | Original | | BLUS-30272 | |
| Ski-Doo X-Team Racing | PC | 1.0 | Original | | SKI844AB-CD | |
| Skies of Arcadia (Disc 1) | DC | 1.000 | Original | | MK-51052-50 | |
| Skies of Arcadia (Disc 2) | DC | 1.000 | Original | | MK-51052-50 | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Skubi-Du! Delo N. 3: Svet! Kamera! Tajna! Скуби-Ду! Дело № 3: Свет! Камера! Тайна! | PC | 8.0.22.0 | Original | | | |
| Skydiving Extreme | PSX | | Original | | SLUS-01392 | |
| Skylanders: Imaginators | XBOX360 | | Original | | AV-2352 | |
| Slam 'n Jam '96 featuring Magic & Kareem Slam 'n Jam '96 featuring Magic & Kareem: Signature Edition | PSX | | Original | | SLES-00076 | |
| Slam 'n Jam '96 featuring Magic & Kareem | PC | | Original | | 76896427322 | |
| Slam 'n Jam '96 featuring Magic & Kareem マジック・ジョンソン・と・カリーム・アブドュール・ジャバーの スラム・ジャム’96 | SS | 1.000 | Original | | T-15905G | |
| Slam 'n Jam '96 featuring Magic & Kareem | PSX | | Original | | SLUS-00022 | |
| Slam 'n Jam '96 featuring Magic & Kareem: Signature Edition | SS | 1.000 | Original | | T-15902H-50 | |
| Slam 'n Jam '96 featuring Magic & Kareem: Signature Edition | SS | 1.000 | Original | | T-15902H | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | T-162035-50 | |
| Slam City with Scottie Pippen (Disc 2) (Juice) | MCD | | Original | | T-162035-50 | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | T-162035-50 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Original | | T-162035-50 | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | 063636, T162035 | |
| Slam City with Scottie Pippen (Disc 2) (Juice) | MCD | | Original | | 063636, T162035 | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | 063636, T162035 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Original | | 063636, T162035 | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | | Original | | WTY744AE-CD | |
| Slam Tennis | XBOX | | Original | | IG-017 | |
| Slam Tennis | PS2 | 1.00 | Original | | SLES-50776 | |
| Slam Tilt | PC | | Original | | | |
| SlamTilt Resurrection (Demon Table) | PC | | Original | | | |
| SlamTilt Resurrection (Pirate Table) | PC | | Original | | | |
| Sled Shred featuring the Jamaican Bobsled Team | WII | | Original | | RVL-R9YE-USA-B0 | |
| Sleeping Dogs: Hong Kong Himitsu Keisatsu スリーピングドッグス 香港秘密警察 | PC | | Original | | SE-G 0040 | |
| Slime Shiyou! すらいムしよう! | PSX | | Original | | SLPS 00504 | |
| Slipstream 5000 | PC | | Original | | | |
| Slipstream 5000 | PC | | Original | | CN000500028 | |
| Slomanny'j mech chast' 1: Ten' tamplierov (Disc 1) Сломанный меч часть 1: Тень тамплиеров | PC | | Original | | | |
| Slomanny'j mech chast' 1: Ten' tamplierov (Disc 2) Сломанный меч часть 1: Тень тамплиеров | PC | | Original | | | |
| Slomannyj mech: Angel smerti Сломанный меч: Ангел смерти | PC | 4.11.16.2006 | Original | | | |
| Slot! Pro 2: Bakuretsu Oozumou Aka & Murasaki スロット!プロ2 ~爆裂大相撲・紅&紫~ | PSX | | Original | | SLPS 03179 | |
| Slot! Pro 5: Naniwa Sakura Fubuki & Shimauta スロット!プロ5 ~浪花桜吹雪&島唄~ | PSX | | Original | | SLPS 03439 | |
| Slot! Pro 8: Shimamusume 30 & Hana Densetsu 25 スロット!プロ8 ~島娘30&花伝説25~ | PSX | | Original | | SLPS 03551 | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Slots Featuring WMS Gaming | PC | 1.0.3 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.1 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.2 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slotter Chou Mania: Antonio Inoki ga Genki ni Suru Pachi-Slot Ki スロッター超マニア アントニオ猪木が元気にするパチスロ機 | PS3 | 01.01 | Original | | BLJM 60326 | |
| Slotter Mania 2: Chounetsu 30 Phi! Hana Hana & KingBary & Hai Hai Siosai スロッターマニア2 超熱30Φ!ハナハナ&キンバリー&ハイシオ | PSX | | Original | | SLPS 03349 | |
| Slotter Mania 3: Bakuryou Houshutsu! Uminchu & Fire Element スロッターマニア3 爆量放出! 海人&ファイアエレメント | PSX | | Original | | SLPS 03414 | |
| Slotter Mania 4: Gekiatsu Youkou! Siolar & King Castle & Kabuto スロッターマニア4 激熱妖光!シオラー&キングキャッスル&兜 | PSX | | Original | | SLPS 03438 | |
| Slotter Mania 5: Gekiuchi Shinzui! Hyper Juggler V & Kita-chan Country & Wonder Review 2 スロッターマニア5激打真髄! ハイパージャグラーV&キタチャンカントリー&ワンダーレビュー2 | PSX | | Original | | SLPS 03468 | |
| Slotter Mania 6: Bakuretsu Sairai! Wadatsumi (2 Types) & Blue Lagoon スロッターマニア6 ~爆裂再来!海神(2タイプ)&ブルー・ラグーン~ | PSX | | Original | | SLPS 03483 | |
| Slotter Mania 7: Gekiatsu! Siosai-musume Seizoroi DX + Apache A スロッターマニア7 激熱!シオサイ姫勢揃いDX+アパッチA | PSX | | Original | | SLPS 03511 | |
| Slotter Mania 8: Miwaku no Takarabako! Jewel Magic 2 & Gold & Silver スロッターマニア8 魅惑の宝箱!ジュエルマジック2&ゴールドアンドシルバー | PSX | | Original | | SLPS 03520 | |
| Slotter Mania 9: Gokunetsu 30 Phi! Haibi & Splash Seven スロッターマニア9 極熱30φ!ハイビ&スプラッシュセブン | PSX | | Original | | SLPS 03533 | |
| Slotter Mania Core: Tokonatsu no Atsusa! Oasis スロッターマニア core 常夏の熱さ!オアシス | PSX | | Original | | SLPS 02960 | |
| Slotter Mania Gaiden: Chouatsu Densetsu! Golden Rookie & Fire V & Ryuuou スロッターマニア外伝 超熱伝説!ゴールデンルーキー&ファイアーV&琉王 | PSX | | Original | | SLPS 03467 | |
| Slotter Mania: Gekinetsu Oki-Slot! Siosai Special スロッターマニア 激熱 沖スロ! シオサイスペシャル | PSX | | Original | | SLPS 03192 | |
| Slotter Up Core 11: Kyojin no Hoshi IV: Seishun Gunzou-hen スロッターUPコア11 巨人の星Ⅳ 青春群像編 | PS2 | 1.01 | Original | | SLPM 55152 | |
| Slotter Up Core 12: Ping Pong スロッターUPコア12 ピンポン | PS2 | 1.03 | Original | | SLPM 55275 | |
| Slotter Up Core 2: Gouda! Minami no Teiou スロッターUPコア2 豪打!ミナミの帝王 | PS2 | 1.01 | Original | | SLPS 20286 | |
| Slotter Up Core 3: Yuda! Doronjo ni Omakase スロッターUPコア3 愉打! ドロンジョにおまかせ | PS2 | 1.01 | Original | | SLPS 20370 | |
| Slotter Up Core 4: Ton-chan Gekida! Jissen Pachi-Slot Ore-izm!! スロッターUPコア4 トンちゃん激打! 実戦パチスロオレ主義!! | PS2 | 1.01 | Original | | SLPS 20378 | |
| Slotter Up Core 6: Bakuenda! Kyojin no Hoshi II スロッターUPコア6 爆炎打! 巨人の星Ⅱ | PS2 | 1.00 | Original | | SLPM 62582 | |
| Slotter Up Core 7: Gekitouda! Street Fighter II スロッターUPコア7 激闘打!ストリートファイターⅡ | PS2 | 1.01 | Original | | SLPM 62622 | |
| Slotter Up Core 8: Gokuenda! Kyojin no Hoshi III スロッターUPコア8 極炎打! 巨人の星Ⅲ | PS2 | 1.03 | Original | | SLPM 62682 | |
| Slotter Up Core 9: Jug Kiwametari! Final Juggler スロッターUPコア9 ジャグ極めたり!ファイナルジャグラー | PS2 | 1.01 | Original | | SLPM 62752 | |
| Slotter Up Mania 10: Pioneer Special III スロッターUPマニア10 パイオニアスペシャルⅢ | PS2 | 1.01 | Original | | SLPM 62778 | |
| Slotter Up Mania 11: 2027 vs. 2027 II スロッターUPマニア11 2027 VS 2027Ⅱ | PS2 | 1.02 | Original | | SLPM 55228 | |
| Slotter Up Mania 2: Kokuchi no Kyoku! Juggler Special スロッターUPマニア2 ~告知の極!ジャグラースペシャル~ | PS2 | 1.01 | Original | | SLPS 20306 | |
| Slotter Up Mania 3: Densetsu Fukkatsu! New Pegasus Special スロッターUPマニア3 伝説復活! ニューペガサススペシャル | PS2 | 1.01 | Original | | SLPS 20338 | |
| Slotter Up Mania 4: Nangoku no Kou! Super Hana Hana & Shiomahal & Oase スロッターUPマニア4 ~南国の香!スーパーハナハナ&シオマール&オアーゼ~ | PS2 | 1.01 | Original | | SLPS 20351 | |
| Slotter Up Mania 5: Soukai Gekida! Mach GoGoGo & Daruma Neko スロッターUPマニア5 ~爽快激打!マッハGoGoGo&だるま猫~ | PS2 | 1.02 | Original | | SLPS 20396 | |
| Slotter Up Mania 6: Oki no Neppuu! Pioneer Special II スロッターUPマニア6 沖の熱風! パイオニアスペシャルⅡ | PS2 | 1.03 | Original | | SLPM 62615 | |
| Slotter Up Mania 7: Saishin Saikyou! Pioneer MAX スロッターUPマニア7 最新最強!パイオニアMAX | PS2 | 1.01 | Original | | SLPM 62693 | |
| Slotter Up Mania 8: Senkou Kokuchi! Juggler Special II スロッターUPマニア8 閃光告知!ジャグラースペシャルⅡ | PS2 | 1.00 | Original | | SLPM 62694 | |
| Slotter Up Mania 9: Atsu Oki da ze! Mensoore-30 & Mensoore 2-30 スロッターUPマニア9 アツ沖だぜ!めんそ~れ-30&めんそ~れ2-30 | PS2 | 1.02 | Original | | SLPM 62773 | |
| Slotter Up Mania: Chou Oki-Slot! Pioneer Special スロッターUPマニア 超沖スロ! パイオニアスペシャル | PS2 | 1.02 | Original | | SLPS 20278 | |
| Sly 3: Honour Among Thieves | PS2 | 1.00 | Original | | SCES-53409 | |
| Sly Cooper: Thieves in Time | PS3 | 01.02 | Original | | BCES-01284 … | |
| Sly Cooper: Thieves in Time | PS3 | 01.02 | Original | | BCUS-98247 | |
| Sly Cooper: Thieves in Time | PS3 | 01.02 | Original | | BCES-01285 | |
| Small House スモールハウス | PC | | Original | | VIRL-6 | |
| Small Soldiers | PSX | | Original | | SLES-01580 | |
| Small Soldiers | PSX | | Original | | SLES-01581 | |
| Small Soldiers | PSX | | Original | | SLES-01582 | |
| Small Soldiers | PSX | | Original | | SLUS-00781 | |
| Small Soldiers: Globotech Design Lab | PC | 1.0.16.57 | Original | | 44106.102 | |
| Small Soldiers: Globotech Design Lab | PC | | Original | | 44106.102 | |
| Small Soldiers: Squad Commander | PC | | Original | | 44107.102 | |
| Small Soldiers: Squad Commander | PC | | Original | | 44107.100 | |
| Small Town Terrors: Pilgrim's Hook | PC | | Original | | | |
| I Smart Kids: Ik ziek zie... Beeldraadsels 1 | PC | | Original | | | |
| Smart Series Presents: Jaja's Adventure | WII | | Original | | RVL-R67E-USA-B0 | |
| Smart Steps: Kindergarten | PC | 1.0 | Original | | | |
| Smarties: Meltdown | PS2 | 1.02 | Original | | SLES-53940 | |
| SmartKids Challenge One | VIS | | Original | | 25-6176 | |
| Smarty Pants: Trivia Fun for Everyone! | WII | | Original | | RVL-RP2P-FRA, RVL-RP2P-NOE | |
| Smarty Pants: Trivia Fun for Everyone! | WII | | Original | | RVL-RP2E-USA | |
| Smash Court Tennis 3 | PSP | 1.00 | Original | | UCES-00758 | |
| Smash Court Tennis 3 スマッシュコートテニス3, 스매시 코트 테니스3 | PSP | 1.00 | Original | | UCKS 45051 … | |
| Smash Court Tennis 3 | PSP | 1.00 | Original | | ULUS-10269 | |
| Smash Court Tennis 3 | XBOX360 | | Original | | NM-2029 | |
| Smash Court Tennis: Pro Tournament | PS2 | 1.04 | Original | | SCES-50810 | |
| Smash Court Tennis: Pro Tournament | PS2 | 1.00 | Original | | SLUS-20286 | |
| Smash Court Tennis: Pro Tournament 2 | PS2 | 1.00 | Original | | SLUS 20933 | |
| Smashing Drive | XBOX | | Original | | NM-001 | |
| Smashing Drive | GC | | Original | | DL-DOL-GSDE-USA | |
| Smert' shpionam Смерть шпионам | PC | | Original | | | |
| Smert' shpionam: Moment istiny Смерть шпионам: Момент истины | PC | | Original | | | |
| Smeshariki: Kalejdoskop igr Смешарики: Калейдоскоп игр | PC | 1.0 | Original | | | |
| Smeshariki: Kalejdoskop igr 2 Смешарики: Калейдоскоп игр 2 | PC | 1.0 | Original | | | |
| Smeshariki: Kalejdoskop igr 4: Geografiya Смешарики: Калейдоскоп игр 4. География | PC | 1.0 | Original | | | |
| Smeshariki: Komp'yuter Yozhika: E'nciklopediya (Disc 1) Смешарики: Компьютер Ёжика. Энциклопедия | PC | 1.0 | Original | | | |
| Smeshariki: Komp'yuter Yozhika: E'nciklopediya (Disc 2) Смешарики: Компьютер Ёжика. Энциклопедия | PC | 1.0 | Original | | | |
| Smeshariki: Nyusha-Princessa. Igra-e'nciklopediya (Disc 1) Смешарики: Нюша-Принцесса. Игра-энциклопедия | PC | 1.0 | Original | | | |
| Smeshariki: Nyusha-Princessa. Igra-e'nciklopediya (Disc 2) Смешарики: Нюша-Принцесса. Игра-энциклопедия | PC | 1.0 | Original | | | |
| Smeshariki: Olimpiada Smesharikov (Disc 1) Смешарики: Олимпиада Смешариков | PC | 1.0 | Original | | | |
| Smeshariki: Olimpiada Smesharikov (Disc 2) Смешарики: Олимпиада Смешариков | PC | 1.0 | Original | | | |
| Smeshariki: Parallel'nye miry Смешарики: Параллельные миры | PC | | Original | | | |
| Smeshariki: Po doroge so Smesharikami (Disc 1) Смешарики: По дороге со Смешариками | PC | 1.0 | Original | | | |
| Smeshariki: Po doroge so Smesharikami (Disc 2) Смешарики: По дороге со Смешариками | PC | 1.0 | Original | | | |
| Smeshariki: Prazdniki so Smesharikami Смешарики: Праздники со Смешариками | PC | 1.0 | Original | | | |
| Smeshariki: Smeshariki idut v poxod (Disc 1) Смешарики: Смешарики идут в поход | PC | 1.1 | Original | | | |
| Smeshariki: Smeshariki idut v poxod (Disc 2) Смешарики: Смешарики идут в поход | PC | 1.1 | Original | | | |
| Smeshariki: Soberi stranu Smesharikov! (Disc 1) Смешарики: Собери страну Смешариков! | PC | 1.0 | Original | | | |
| Smeshariki: Soberi stranu Smesharikov! (Disc 2) Смешарики: Собери страну Смешариков! | PC | 1.0 | Original | | | |
| Smeshariki: V poiskax Bibi Смешарики: В поисках Биби | PC | 1.1 | Original | | | |
| Smilde | CDI | | Original | | | |
| Smiley World: Island Challenge | WII | | Original | | RVL-RIDP-EUR | |
| Smiley World: Island Challenge | WII | | Original | | RVL-RIDE-USA-B0 | |
| Smilingüido em: Desafio na Floresta | PC | | Original | | | |
| The Smithsonian Presents: Stamps: Windows on the World | CDI | | Original | | 310690011-2, 699 011-2, 812 0031 | |
| The Smithsonian Presents: Stamps: Windows on the World | CDI | | Original | | 310690011-2 | |
| Smuggler's Run 2: Hostile Territory | PS2 | 1.01 | Original | | SLES-50341 … | |
| Smuggler's Run 2: Hostile Territory | PS2 | 1.00 | Original | | SLUS-20204 | |
| Smurfarna: Operation Smurfan Smurfarna: Operation Smurfan: Jakten på den Magiska Formeln | PC | | Original | | TELEPSSW5011 | |
| The Smurfs: The Teletransportsmurf Hupikék Törpikék: Teletranszportörp | PC | | Original | | | |
| SN Systems Installation Disc v2.0 | PC | 2.0 | Original | | | |
| Snatcher CD-ROMantic スナッチャー・シーディロマンティック | PCE | | Original | | KMCD2002 | |
| Snatcher CD-ROMantic: Pilot Disk スナッチャー・シーディロマンティック パイロット・デイスク | PCE | | Original | | KMCD2001 | |
| Sneak King | XBOX | | Original | | MS-211 | |
| Snezhok: Priklyucheniya v kosmose Снежок: Приключения в космосе | PC | 1.1.6.0 | Original | | | |
| Sniper Elite | XBOX | | Original | | MI-013 | |
| Sniper Elite | XBOX | | Original | | MI-013 | |
| Sniper Elite | XBOX | | Original | | MI-013 | |
| Sniper Elite III: Ultimate Edition | PS3 | 01.01 | Original | | BLES-02145 | |
| Sniper Elite III: Ultimate Edition | PS3 | 01.00 | Original | | BLUS-31532 | |
| Sniper Elite III: Ultimate Edition | XBOX360 | | Original | | FO-2051 | |
| Sniper Elite V2 スナイパー エリートV2 | PS3 | 01.01 | Original | | BLJM 60503 | |
| Sniper Elite V2: Game of the Year Edition | PS3 | 01.00 | Original | | BLES-01812 | |
| Sniper Elite V2: Silver Star Edition Sniper Elite V2: Game of the Year Edition | XBOX360 | | Original | | FO-2024 | |
| Sniper Elite: Armiya t'my Sniper Elite: Армия тьмы | PC | | Original | | | |
| Sniper Elite: Zombie Army | PC | | Original | | MTC000853-D | |
| Sniper: Ghost Warrior 2 スナイパー ゴーストウォリアー2 | PS3 | 01.00 | Original | | BLJM 60539 | |
| SnoCross 2 featuring Blair Morgan | PS2 | 1.02 | Original | | SLES-54157 | |
| SnoCross 2 featuring Blair Morgan | PS2 | 1.04 | Original | | SLUS 21130 | |
| SnoCross Championship Racing Sno-Cross Championship Racing | PSX | | Original | | SLES-02763 | |
| SnoCross Championship Racing Sno-Cross Championship Racing | DC | 1.000 | Original | | 830-0223-50, T-17722D-50 | |
| SnoCross Championship Racing Sno-Cross Championship Racing | PSX | | Original | | SLUS-01093 | |
| SnoCross Championship Racing Sno-Cross Championship Racing | DC | 1.000 | Original | | T-40207N | |
| Snoopy: The Case of the Missing Blanket | CDTV | | Original | | | |
| Snoopy's Campfire Stories | PC | | Original | | | |
| Snowmobile Racing | PC | | Original | | | |
| Snowmobile Racing | PC | | Original | | 04-17527CD | |
| Soccer America: International Cup | PS2 | 1.00 | Original | | SLUS-20196 | |
| Soccer Kantoku Saihai Simulation: Formation Final サッカー監督采配シミュレーション FORMATION FINAL | PS2 | 1.02 | Original | | SLPM 65372 | |
| Soccer Mania | PS2 | 1.00 | Original | | SLUS-20456 | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.00 | Original | | SCES-52306 | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.00 | Original | | SCPS 15065 | |
| SOCOM: Confrontation | PS3 | 01.01 | Original | | BCES-00173 | |
| SOCOM: Special Forces | PS3 | 01.00 | Original | | BCES-00938 … | |
| SOCOM: Special Forces | PS3 | 01.00 | Original | | BCES-00939 | |
| SOCOM: U.S. Navy SEALs: Confrontation | PS3 | 01.00 | Original | | BCUS-98183 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo | PSP | 1.00 | Original | | UCES-00038 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 2 소콤 U.S.네이비 씰 파이어팀 브라보 2 | PSP | 1.00 | Original | | UCKS 45043 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 3 소콤 U.S.네이비 씰 파이어팀 브라보 3 | PSP | 1.01 | Original | | UCKS 45128 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 3 | PSP | 1.01 | Original | | UCUS-98716 | |
| SOCOM: U.S. Navy SEALs: Tactical Strike | PSP | 1.00 | Original | | UCES-00855 | |
| SOCOM: U.S. Navy SEALs: Tactical Strike | PSP | 1.00 | Original | | UCUS-98649 | |
| Soft de Hard na Monogatari ソフトでハードな物語 | FMT | | Original | | | |
| Soft de Hard na Monogatari 2 ソフトでハードな物語2 | FMT | | Original | | HMA-214 | |
| The Soft Rock Games Collection CD | ARCH | | Original | | | |
| Softgold Presents: LucasArts Top Adventures CD-ROM Edition | PC | | Original | | | |
| Softkey Home/Family Bundle | PC | | Original | | HFB344CB-CD | |
| Software Contest Nyuusen Sakuhinshuu 1 ソフトウェア・コンテスト 入選作品集 1 | FMT | | Original | | HMC-139 | |
| Software Contest Nyuusen Sakuhinshuu 1 ソフトウェア・コンテスト 入選作品集 1 | FMT | Rev A | Original | | HMC-139A | |
| Software Contest Nyuusen Sakuhinshuu 1 ソフトウェア・コンテスト 入選作品集 1 | FMT | Rev B | Original | | HMC-139B | |
| Software Contest Nyuusen Sakuhinshuu 2 ソフトウェア・コンテスト 入選作品集 2 | FMT | | Original | | HMD-189 | |
| Software Contest Nyuusen Sakuhinshuu 3 ソフトウェア・コンテスト 入選作品集 3 | FMT | | Original | | HME-200 | |
| Software JukeBox: Home & Entertainment Edition: Vol. 1 No. 1 | PC | | Original | | CDRM1006830 | |
| The Software Toolworks Presents: Maniac Sports | MAC | | Original | | 2200820-590001 / I034100 | |
| Software Tycoon: Der Spielemanager | PC | | Original | | | |
| Softwarehits Made in Germany 94/95 | PC | | Original | | | |
| Sol Trigger ソールトリガー | PSP | 1.01 | Original | | ULJM 06093 | |
| Soldaty Anarxii Солдаты Анархии | PC | 1.1.2.178 | Original | | RUSSOBIT-M 2003/362 | |
| Soldiers: Heroes of World War II (Disc 1) | PC | 1.05.1 | Original | | MSOLCDEU00 | |
| Soldiers: Heroes of World War II (Disc 2) | PC | 1.05.1 | Original | | MSOLCDEU01 | |
| Söldner: Marine Corps | PC | | Original | | ROSOELDNER0014LAB | |
| Solitaire & Mahjong | WII | | Original | | RVL-RSOE-USA-B0 | |
| Solitaire Antics Ultimate | PC | 1.0.3L | Original | | | |
| Solitaire Mania | MAC | | Original | | PART NO. 05SMM-01 | |
| Solitaire Master | PC | | Original | | 20-1280-10 | |
| Solitaire Master 2 | PC | 2.0 | Original | | 11-2806-10 | |
| Solitaire Master 2 | PC | 2.1 | Original | | 02-6306-10 | |
| Solitaire Master 4 | PC | 1.0 | Original | | 02-8156-10 | |
| Solitaire Master 5 | PC | 1.0 | Original | | 02-2153-10 | |
| A Sombra do Zorro | PC | | Original | | INFOG 095 | |
| Somewhere: Une Envie de Naturel: Printemps 96 | CDI | | Original | | | |
| Sonic & All-Stars Racing Transformed | PC | | Original | | SEGA-PC146 | |
| Sonic & All-Stars Racing Transformed ソニック&オールスターレーシング TRANSFORMED | PS3 | 01.00 | Original | | BLJM 61145 | |
| Sonic & All-Stars Racing Transformed | XBOX360 | | Original | | SE-2141 | |
| Sonic & Knuckles Collection | PC | | Original | | MK 85037-50 | |
| Sonic 3D: Flickies' Island | PC | | Original | | MK 85064-50 | |
| Sonic 3D: Flickies' Island | SS | 1.000 | Original | | MK81062-50 | |
| Sonic Adventure | DC | 1.003 | Original | | MK-51000-50 | |
| Sonic Adventure 2 | DC | 1.008 | Original | | MK-51117-50 | |
| Sonic CD | PC | | Original | | MK 85015-50 | |
| Sonic Gems Collection | GC | | Original | | DL-DOL-G2XP-EUR | |
| Sonic Gems Collection ソニック ジェムズ コレクション | GC | | Original | | DL-DOL-G2XJ-JPN | |
| Sonic Gems Collection ソニック ジェムズ コレクション | PS2 | 1.01 | Original | | SLPM 66074 | |
| Sonic Generations: Shiro no Jikuu ソニックジェネレーションズ 白の時空 | PS3 | 01.00 | Original | | BLJM 60334 | |
| Sonic Heroes ソニック ヒーローズ | PS2 | 1.01 | Original | | SLPM 65431 | |
| Sonic Jam | SS | 1.000 | Original | | MK81079-50 | |
| Sonic Jam ソニック・ジャム | SS | 1.005 | Original | | GS-9147 | |
| Sonic Jam | SS | 1.004 | Original | | 81079 | |
| Sonic Mega Collection ソニック メガコレクション | GC | | Original | | DL-DOL-GSOJ-JPN | |
| Sonic Mega Collection Plus ソニック メガコレクション プラス | PS2 | 1.00 | Original | | SLPM 65758 | |
| Sonic Mega Collection Plus 소닉 메가 컬렉션 플러스 | PS2 | 1.00 | Original | | SLKA 25233 | |
| Sonic R | PC | | Original | | MK 85076-50 | |
| Sonic R | SS | 1.000 | Original | | MK81800-50 | |
| Sonic Riders ソニックライダーズ | PS2 | 1.02 | Original | | SLPM 66281 | |
| Sonic Shuffle | DC | 1.000 | Original | | MK-51060-50 | |
| Sonic the Hedgehog ソニック・ザ・ヘッジホッグ | PS3 | 01.01 | Original | | BLJM 60006 | |
| Sonic to Himitsu no Ring ソニックと秘密のリング | WII | | Original | | RVL-RSRJ-JPN | |
| Sonic World Adventure ソニック ワールドアドベンチャー | PS3 | 01.00 | Original | | BLJM 60112 | |
| Sony Computer Entertainment Europe: ECTS 2000 Information Card | PC | | Original | | | |
| Sony Computer Science Kenkyuusho Mogi Kenichirou Hakushi Kanshuu: Nou ni Kaikan Aha Taiken ソニーコンピュータサイエンス研究所 茂木健一郎博士監修 脳に快感 アハ体験! | PSP | 1.00 | Original | | ULJM-05135 | |
| Sony Computer Science Kenkyuusho Mogi Kenichirou Hakushi Kanshuu: Nou ni Kaikan Minna de Aha Taiken ソニーコンピュータサイエンス研究所 茂木健一郎博士監修 脳に快感 みんなでアハ体験! | PSP | 1.01 | Original | | ULJM-05189 | |
| Sony Image Converter 2: Ver.2.1 | PC | 2.1.00.14241 | Original | | MSSW-IC2 | |
| Sophie no Atelier: Fushigi na Hon no Renkinjutsushi ソフィーのアトリエ ~不思議な本の錬金術士~ | PS3 | 01.01 | Original | | BLJM 61309 | |
| Sora no Kiseki: Material Collection Portable 空の軌跡 マテリアルコレクション ポータブル | PSP | 1.00 | Original | | ULJM 05307 | |
| Sorairo no Organ Remix 空色の風琴 Remix | PS2 | 1.01 | Original | | SLPM 65848 | |
| Sorcer Kingdom ソーサル・キングダム | PC-98 | | Original | | AYPIO-001 | |
| Soreike! Anpanman: Tanoshii Eigo Asobi それいけ! アンパンマン ~たのしいえいごあそび~ | FMT | | Original | | FMB-3010 | |
| Sorority House: An Interactive Game of Hide and Peek | PC | 1.0 | Original | | | |
| Sortilèges: Rage of Mages II Rage of Mages II: Necromancer | PC | | Original | | | |
| Soshite Bokura wa, ... and He Said そして僕らは、・・・and he said | PS2 | 1.01 | Original | | SLPM 65971 | |
| Soshite Kono Sora ni Kirameku Kimi no Uta そしてこの宇宙にきらめく君の詩 | PS2 | 1.02 | Original | | SLPM 66351 | |
| Soshite Kono Sora ni Kirameku Kimi no Uta XXX そしてこの宇宙にきらめく君の詩 XXX | PS2 | 1.02 | Original | | SLPM 66659 | |
| Sotsugyou M: Seito Kaichou no Karei naru Inbou (Disc 1) 卒業M ~生徒会長の華麗なる陰謀~ | PSX | | Original | | SLPS 01444 | |
| Sotsugyou M: Seito Kaichou no Karei naru Inbou (Disc 2) 卒業M ~生徒会長の華麗なる陰謀~ | PSX | | Original | | SLPS 01445 | |
| Sotsugyou Shashin: Miki 卒業写真 ~美姫~ | PCE | | Original | | CJCD 4005 | |
| Sotsugyou: 2nd Generation 卒業 2nd Generation | PS2 | 1.01 | Original | | SLPM 66294 | |
| Sotsugyou: Graduation 卒業 グラデュエーション | MAC | | Original | | BCRM-0012 | |
| Souko Mania 2 倉庫マニア2 | PC | | Original | | MSDJ-02012 | |
| Soukoban: Nanmon Shinan 倉庫番 難問指南 | PSX | | Original | | SLPS 02010 | |
| Soukoku no Kusabi: Hiiro no Kakera 3 蒼黒の楔 緋色の欠片3 | PS2 | 1.01 | Original | | SLPM 55040 | |
| Soukou Kihei Votoms 装甲騎兵ボトムズ | PS2 | 1.01 | Original | | SLPS 25827 | |
| Soukou Kihei Votoms Gaiden: Ao no Kishi Berserga Monogatari 装甲騎兵ボトムズ外伝 ~青の騎士 ベルゼルガ物語~ | PSX | | Original | | SCPS 45115 … | |
| Soukou Kihei Votoms: Koutetsu no Gunzei 装甲騎兵ボトムズ 鋼鉄の軍勢 | PSX | | Original | | SLPS 02315 | |
| Soukou Kihei Votoms: Lightning Slash 装甲騎兵ボトムズ ライトニング・スラッシュ | PSX | | Original | | SLPS 01961 | |
| Soukou Kihei Votoms: Woodo Kummen 装甲騎兵ボトムズ ~ウド・クメン編~ | PSX | | Original | | SLPS 01331 | |
| Soukou no Kihei: Space Griffon 蒼鋼の騎兵 -SPACE GRIFFON- | DC | 1.001 | Original | | T-39601M | |
| Soul Cradle: Sekai o Kurau Mono ソウルクレイドル 世界を喰らう者 | PS2 | 1.03 | Original | | SLPS 25739 | |
| Soul Eater: Monotone Princess ソウルイーター モノトーン プリンセス | WII | | Original | | RVL-RSEJ-JPN | |
| Soul Link Extension ソウルリンク エクステンション | PS2 | 1.02 | Original | | SLPM 66437 | |
| Soul of the Samurai | PSX | | Original | | SLUS-00822 | |
| Soulcalibur ソウルキャリバー | DC | 2.000 | Original | | T-1401M | |
| Soulcalibur II 劍魂II | XBOX | | Original | | NM-003 | |
| Soulcalibur II | XBOX | | Original | | NM-003 | |
| Soulcalibur II ソウルキャリバーⅡ | XBOX | | Original | | NM-003 | |
| Sound Novel Machi (Disc 1) (10.11-10.13 Incl.) サウンドノベル 街 | SS | 1.001 | Original | | T-34001G | |
| Sound Novel Machi (Disc 2) (10.13-10.15 Incl.) サウンドノベル 街 | SS | 1.001 | Original | | T-34001G | |
| Sound Novel Machi (Disc 2) (10.13-10.15 Incl.) サウンドノベル 街 | SS | 1.001 | Original | | T-34001G | |
| Soundtrack1: The Definitive Xbox Compilation (Disc 2) | PC | | Original | | 314 584 098 2 | |
| Souten no Shiroki Kami no Kura: Great Peak 蒼天の白き神の座 -GREAT PEAK- | PSX | | Original | | SCPS 10058 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art": Special CD-ROM サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" SPECIAL CD-ROM | PC | | Original | | ORRS-1 | |
| Souzou Sozai: Europe no Mado Vol. 2 創造素材 ヨーロッパの窓 Vol.2 | PHOTO-CD | | Original | | ERV2 | |
| Souzou Sozai: Umi Vol. 1 創造素材 海 Vol.1 | PHOTO-CD | | Original | | SEVI-1049 | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Camp | WII | | Original | | RVL-RIYP-EUR | |
| Space Camp | WII | | Original | | RVL-RIYE-USA | |
| Space Chimps | PS2 | 1.00 | Original | | SLES-55348 … | |
| Space Chimps | XBOX360 | | Original | | BT-2004 | |
| Space Chimps | WII | | Original | | RVL-RP9P-EUR | |
| Space Chimps | WII | | Original | | RVL-RP9X-EUU | |
| Space Chimps | PS2 | 1.02 | Original | | SLES-55340 | |
| Space Chimps | XBOX360 | | Original | | BT-2004 Version: 1. | |
| Space Chimps | WII | | Original | | RVL-RP9E-USA | |
| Space Chimps | PS2 | 1.03 | Original | | SLUS 21783 | |
| Space Clash Space Clash: Das letzte Imperium | PC | | Original | | | |
| Space Dynagon Kai スペース大納言(改 | PC | | Original | | MSCD-0026 | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Space Empires V Космическая Империя V | PC | 1.66 | Original | | | |
| Space Fishermen スペースフィッシャーメン | PS2 | 1.00 | Original | | SCPS 11025 | |
| Space in Motion: Future Trade | PC | 1.01 | Original | | | |
| Space Invada!! Type Shinai to Tama ga Denai. SPACE INVA打!! / SPACE INVADERS!! タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Space Invaders 2000 スペースインベーダー2000 | PSX | | Original | | SLPM 86153 | |
| Space Invaders Anniversary スペースインベーダー アニバーサリー | PS2 | 1.02 | Original | | SLPM 62354 | |
| Space Invaders Extreme | PSP | 1.00 | Original | | ULES-01078 | |
| Space Invaders Extreme スペースインベーダーエクストリーム | PSP | 1.01 | Original | | UCAS 40194 … | |
| Space Invaders Extreme | PSP | 1.00 | Original | | ULUS-10346 | |
| Space Invaders Pocket スペースインベーダー ポケット | PSP | 1.04 | Original | | ULJM 05015 | |
| Space Invaders X スペース・インベーダーX | PSX | | Original | | SLPM 86419 | |
| Space Invaders: Galaxy Beat スペースインベーダー ギャラクシービート | PSP | 1.02 | Original | | ULJM 05045 | |
| Space Invaders: The Original Game Space Invaders '95 | PC | | Original | | | |
| Space Invaders: The Original Game スペースインベーダー | PC | | Original | | | |
| Space Invaders: The Original Game スペース・インベーダー | PCE | | Original | | NAPR-1050 | |
| Space Marisar スペースマリサー | PC | 1.00 | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Raiders スペースレイダース | PS2 | 1.01 | Original | | SLPM 62275 | |
| Space Sniper Maya (Disc 1) スペーススナイパー マヤ | PC | | Original | | GOR-0004 1/2 | |
| Space Sniper Maya (Disc 2) スペーススナイパー マヤ | PC | | Original | | GOR-0004 2/2 | |
| Space Station Manager Космоград | PC | 1.2.1 Rus | Original | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Venus Starring Morning Musume. スペースヴィーナス starring モーニング娘。 | PS2 | 1.00 | Original | | SRPM 70201 | |
| Space-Dude: Der Retter des Universums | PC | | Original | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| Spartan: Kodai Greece Eiyuuden スパルタン 古代ギリシャ英雄伝 | PS2 | 1.02 | Original | | SLPM 66444 | |
| Spaß am Turnierreiten Equestriad 2001 | PC | | Original | | | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-36816D-50 | |
| Spawn: In the Demon's Hand スポーン イン ザ デーモンズ ハンド | DC | 1.003 | Original | | T-1216M | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-1216N | |
| Spawn: Unmei no Kusari SPAWN ~運命の鎖~ | PS2 | 1.01 | Original | | SLPS 25370 | |
| Spec Ops II: Omega Squad | DC | 1.002 | Original | | T-45004D-50 | |
| Spec Ops II: Omega Squad | DC | 1.008 | Original | | T-41704N | |
| Spec Ops II: U.S. Army Green Berets | PC | | Original | | | |
| Spec Ops: Airborne Commando | PSX | | Original | | SLES-03891 | |
| Spec Ops: Airborne Commando | PSX | | Original | | SLUS-01447 | |
| Spec Ops: Platinum Collection (Disc 2) | PC | 1.0 | Original | | | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 3) | PC | 1.0 | Original | | | |
| Special Jinsei Game Special 人生ゲーム | GC | | Original | | DL-DOL-GLIJ-JPN | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Specnaz: Antiterror. Missija na Balkanah (Disc 1) Спецназ: Антитеррор. Миссия на Балканах | PC | | Original | | | |
| Spectral Force: Radical Elements スペクトラルフォース ラジカルエレメンツ | PS2 | 1.06 | Original | | SLPM 65669 | |
| Spectral Souls: Resurrection of the Ethereal Empires | PSP | 1.00 | Original | | ULUS-10076 | |
| Spectral vs. Generation スペクトラル VS ジェネレーション | PS2 | 1.02 | Original | | SLPM 62727 | |
| Spectral vs. Generation スペクトラル VS ジェネレーション | PSP | 1.06 | Original | | UCAS 40102 … | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Speech Trainer V1.0 L10 スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Devils スピード・デビル | DC | 1.005 | Original | | T-17702M | |
| Speed King: Neo Kobe 2045 スピードキング | PSX | | Original | | SLPM 86013 | |
| Speed Machines | PSX | | Original | | SLES-03930 | |
| Speed Machines 3 | PS2 | 1.03 | Original | | SLES-53920 | |
| Speed Pack Streets of Moscow | Classic Car Racing | PC | | Original | | | |
| Speed Racer Speed Racer: The Videogame | PS2 | 1.01 | Original | | SLES-55075 | |
| Speed Racer Speed Racer: The Videogame | PS2 | 1.02 | Original | | SLUS 21812 | |
| Speed Racer: The Videogame | WII | | Original | | RVL-R3PP-EUR | |
| Speed Racer: The Videogame | WII | | Original | | RVL-R3PE-USA | |
| Het Speelhuis van Muis | PC | | Original | | | |
| Spelling Challenges and More! | PSP | 1.00 | Original | | ULUS 10255 | |
| Speltajm: Djungelns kojigaste CD-ROM | PC | | Original | | | |
| Sphinx and the Cursed Mummy | XBOX | | Original | | TQ-035 | |
| Sphinx and the Cursed Mummy | GC | | Original | | DL-DOL-GXPP-EUR, DL-DOL-GXPP-NOE | |
| Sphinx and the Cursed Mummy | PS2 | 1.00 | Original | | SLES-51831 … | |
| Sphinx and the Cursed Mummy 스핑크스와 저주받은 미이라 | XBOX | | Original | | TQ-035 | |
| Sphinx and the Cursed Mummy 스핑크스와 저주받은 미이라 | PS2 | 1.00 | Original | | SLKA 25018 | |
| Sphinx and the Cursed Mummy | XBOX | | Original | | TQ-035 | |
| Sphinx and the Cursed Mummy | GC | | Original | | DL-DOL-GXPE-USA | |
| Sphinx and the Cursed Mummy | PS2 | 1.00 | Original | | SLUS-20482 | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spider-Man | GC | | Original | | DL-DOL-GSMP-EUR, DL-DOL-GSMP-UKV | |
| Spider-Man | PC | | Original | | 31131.101.UK | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50812 | |
| Spider-Man | DC | 1.000 | Original | | T-13011D-50 | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.UK | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.UK | |
| Spider-Man | GC | | Original | | DL-DOL-GSMF-FRA | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50813 | |
| Spider-Man | GC | | Original | | DL-DOL-GSMD-NOE | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spider-Man | PSX | | Original | | SLES-02888 … | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50814 | |
| Spider-Man スパイダーマン | XBOX | | Original | | CC-010 | |
| Spider-Man スパイダーマン | GC | | Original | | DL-DOL-GSMJ-JPN | |
| Spider-Man スパイダーマン | PS2 | 1.01 | Original | | SLPM 65205 | |
| Spider-Man 스파이더맨 | XBOX | | Original | | AV-006 | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50965 | |
| Spider-Man | PC | | Original | | 31131.101.US | |
| Spider-Man | GC | | Original | | DL-DOL-GSME-USA | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spider-Man | HS | 1.0 (USE1) | Original | | K6593-9609 | |
| Spider-Man | PS2 | 1.00 | Original | | SLUS-20336 | |