Region | Title | System | Version | Edition | Languages | Serial | Status |
| Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scrabble Interactive: 2003 Edition | PC | | Focus Essential | | ESS493 | |
| Scrabble Interactive: 2003 Edition | PC | | Original | | | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Complete | PC | | Original, Monopoly & Scrabble Complete, Scrabble Complete/Jeopardy 2003 | | 11290-CD, Part # 23970CD | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| The Scottish Open: Virtual Golf | PC | | Euro Power Pack | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| Scotland Yard | PC | | Original | | | |
| Scotland Yard | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooby-Doo! Showdown in Ghost Town | PC | | GSP | | 1066A | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0.1.8 | SoftKey | | SGW854BB, SGW854BB-CD | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0 | Original | | SGW844AB-CD | |
| Scooby-Doo! Pierwsze Strachy | PC | | Demo | | | |
| Scooby-Doo! Phantom of the Knight | PC | | GSP | | 1064A | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooby-Doo! Phantom of the Knight | PC | | SoftKey | | SPK854BB-CD | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Le Mystere du Parc Fantome | PC | | Original | | | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.0 | | | SCA844AB | |
| Scooby-Doo! Jinx at the Sphinx | PC | | GSP | | 1065A | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | | GSP | | 1063A | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Scooby-Doo 2: Monsters Unleashed | PC | | PC Fun Club | | PFC028/D | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | Original | | | |
| Scooby Doo: Strachy na Lachy | PC | | | | | |
| Scissors 'n' Stones | PC | | Original | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| The Sci-Fi Collection | PC | | Original | | | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| Schwarzschild GXR: Toki no Tsukaibito シュヴァルツシルトGXR 時現の遣人 | PC | | Original | | ID NO.9674-68-01 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | TopWare | | SPI 031 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | Gold Games (CD 4) | | SPI 035 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | TopWare | | SPI 031 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | Gold Games (CD 3) | | SPI 035 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Schatten über Riva | PC | 1.00 | Original | | SPI 032 | |
| Das Schwarze Auge: Schatten über Riva | PC | | Gold Games 2 (CD 4) | | | |
| Das Schwarze Auge: Schatten über Riva | PC | | Gold Games 2 (CD 4) | | SPI 046 | |
| Das Schwarze Auge: Schatten über Riva | PC | | All You Can Play: Adventure & Fantasy | | | |
| Das Schwarze Auge: Schatten über Riva | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Der Schuh des Manitu Der Schuh des Manitu: Das Computerspiel zum Film | PC | | Original | | | |
| Les Schtroumpfs: Le Téléportaschtroumpf | PC | | Original | | SCHTRFR5011 | |
| Schrei-Ten SCHREI・TEN シュライテン | PC | | Shokai Genteiban | | PISCKISS-01 | |
| Schoolmates: The Mystery of the Magical Bracelet | PC | | Original | | | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Schoolhouse Rock! Math Rock | PC | | Smart Saver | | SHR744AE-CD | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Tycoon | PC | v1 | Original | | | |
| School Tycoon | PC | | Original | | | |
| School Tycoon | PC | | Scholastic | | P/N: CDR 21661-1R | |
| School Rumble: Neru Musume wa Sodatsu.: DTA Daisuki Tenma Accessory スクールランブル ねる娘は育つ。 DTA<大好き 天満アクセサリー> | PC | | DX Pack | | MII-012 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus: Jungle no Fushigi マジック スクール バス ジャングルのふしぎ | PC | | Original | | PRIR-01005 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Scholastic's The Magic School Bus Discovers Flight: Activity Center | PC | 1.0.0.2 | Original | | 0201 Part No. X06-16068 | |
| Schmidt Interaktivspaß: Spiele für Kids | PC | | Original | | S0022620 | |
| Schmidt Interaktivspaß: Solitaire | PC | 1.0.0.0 | Original | | S0023093 | |
| Schmidt Interaktivspaß: Skat | PC | | Original | | S0022595 | |
| Schmidt Interaktivspaß: Mahjong | PC | | Original | | S0023095 | |
| Schmidt Interaktivspass: Kartenspiele | PC | 1.0.0.0 | Original | | S0022612 | |
| Schmidt Interaktivspass: Doppelkopf | PC | 1.0.0.0 | Original | | S0022421 | |
| Schmidt Interaktivspaß: Brettspiele | PC | | Original | | S0022616 | |
| Schleichfahrt | PC | | Original, Classics | | | |
| Schleichfahrt | PC | | | | | |
| Schleichfahrt | PC | | Original | | | |
| Schleichfahrt | PC | | Hemming | | | |
| Die Schlaue Bande: 6. Klasse Lernsystem | PC | | Original | | | |
| Die Schlaue Bande: 5. Klasse Lernsystem | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Playable Demo) | PC | 0.99 | Demo | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | | Original | | | |
| Schiff-Simulator 2008 | PC | | Original | | Artikelnummer 31114 | |
| Schiff-Simulator 2008 Ship Simulator 2008 | PC | | Original | | | |
| Schiff-Simulator 2005 Virtual Sailor 6.8 | PC | | Original | | 31059 | |
| Schiene & Strasse: Der 3D-Transport-Manager: 1820-2020 | PC | | Original | | | |
| Der Schatz von El Dorado | PC | | Original | | | |
| Der Schatz der Versunkenen Brigantine | PC | | Original | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Save Planet Polluto | PC | 1.0 | Original | | | |
| Savage: The Ultimate Quest for Survival | PC | 1.0 | | | | |
| Savage: The Battle for Newerth | PC | 1.0 | Original | | | |
| Savage: The Battle for Newerth | PC | V471 | Bundle Version ASUS OEM | | | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage 2: A Tortured Soul | PC | 01.00.00 | Original | | | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Satsui no Shoumei: In the 1st Degree: Making CD-ROM 殺意の証明 イン ザ ファースト ディグリー メイキングCD-ROM | PC | | Hibaihin | | IP-081M | |
| SATS Test & Learn Science Key Stage 2 (Disc 2) | PC | | Original | | | |
| SATS Test & Learn Science Key Stage 2 (Disc 1) | PC | | Original | | | |
| SATS Test & Learn Maths Key Stage 2 (Disc 2) | PC | | Original | | | |
| SATS Test & Learn Maths Key Stage 2 (Disc 1) | PC | | Original | | | |
| SATS Test & Learn English Key Stage 2 (Disc 2) | PC | | Original | | | |
| SATS Test & Learn English Key Stage 2 (Disc 1) | PC | | Original | | | |
| Satomi: Yami no Kyouzou SATOMI 闇の鏡像 | PC | | Original | | | |
| SAT.1 Swing | PC | | Original | | | |
| SAT.1 Superball | PC | | Original | | | |
| SAS: Anti-Terror Force | PC | | | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Dice | | DMM 001631 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 001631 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 011143 | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Claus: Gold Edition | PC | | Original | | PF5025 | |
| Sansuu Senshi Blaster: Anzan Power de Spot-kun o Sukue! 算数戦士ブラスター 暗算パワーでスポット君を救え! | PC | | Original | | | |
| Sanrio Tiny Park Vol. 2 サンリオ タイニー・パーク Vol.2 | PC | | | | RS-9 | |
| Sanrio Character Encyclopedia サンリオキャラクター大百科 | PC | | | | R-10 | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Sanitarium (Disc 3) | PC | 1.0 | Original | | CS090738 | |
| Sanitarium (Disc 1) | PC | 1.0 | Original | | CD090736 | |
| Sanitarium (Disc 3) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 1) | PC | 1.00 RC15 / Build 836 | Original | | | |
| Sanitarium | PC | | Demo | | | |
| Sanitarium (Disc 3) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 1) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | 1.0 | Original | | CS090737 | |
| Sanguozhi Internet Wangjiwangluban 三國志 Internet 網際網路版 | PC | 1.01 | Original | | | |
| Sanguozhi Battlefield 三國志 Battlefield | PC | 1.01 | Original | | 02.09.01021 | |
| Sangokushi: Special Data CD 三國志 スペシャルデータCD | PC | | PC Game Bundle | | KOEI-S10DATA | |
| Sangokushi: Returns 三國志 リターンズ | PC | 1.0 | Kikan Gentei Hatsubai | | | |
| Sangokushi: Returns 三國志 リターンズ | PC | 1.0 | Original, Koei Teiban Series | | KN10-98102, KN11-06102 | |
| Sangokushi: Returns 三國志 リターンズ | PC | 1.0 | Original | | KN10-98101 | |
| Sangokushi X Power-Up Kit 三國志Ⅹ パワーアップキット | PC | 1.2.0.1 | Sourcenext Selection | | | |
| Sangokushi X Power-Up Kit 三國志Ⅹ パワーアップキット | PC | 1.0.0.0 | Original | | KOEI-20933 | |
| Sangokushi VI Power-Up Kit 三國志Ⅵ パワーアップキット | PC | 1.0 | Original | | KN11-90103 | |
| Sangokushi V Power-Up Kit 三國志Ⅴ パワーアップキット | PC | 1.0 | Original | | KN11-30104 | |
| Sangokushi V Power-Up Kit 三國志Ⅴ パワーアップキット | PC | 1.0 | Original | | KN11-30103 | |
| Sangokushi Tai Sen: Dairyuusei 三国志戴閃-大流星- | PC | 1.01 | Original | | | |
| Sangokushi IV with Power-Up Kit 三國志Ⅳ with パワーアップキット | PC | 1.0 | Original | | KN10-67103 | |
| Sangokushi IV with Power-Up Kit 三國志Ⅳ with パワーアップキット | PC | 1.0 | Original | | KN10-67104 | |
| Sangokushi IV with Power-Up Kit 三國志Ⅳ with パワーアップキット | PC | 1.0 | Genteiban Koei Summer Campaign 2 | | KN10-67104 | |
| Sangokushi Gekiten 三國志撃天 | PC | | Original | | | |
| Sangokushi Eiyuuden: Gold Edition (Disc 2) (Game CD-ROM) 三国志英雄伝 ゴールドエディション | PC | | Original | | 007J1341TA | |
| Sangokushi Eiyuuden: Gold Edition (Disc 1) (Install CD-ROM) 三国志英雄伝 ゴールドエディション | PC | | Original | | 007J1341TA | |
| Sangokushi Eiketsuden 三國志英傑伝 | PC | 1.0 | Value Set Series | | KN10-82105 | |
| Sangokushi Battlefield 三國志 Battlefield | PC | 1.01 | Original | | KOEI-17292 | |
| Sangokushi Battlefield 三國志 Battlefield | PC | | βversion | | β-17292 | |
| Sangokushi 11 Power-Up Kit 三國志11 パワーアップキット | PC | 1.0 | Original | | KOEI-25051 | |
| Sandwich Sisters サンドイッチ三姉妹 | PC | | | | SCR-002 | |
| Sandwarriors: The Battle for the Sun Throne | PC | 1.0 | Original | | | |
| Sandwarriors: The Battle for the Sun Throne | PC | 1.0 | Original | | | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sanae-chan wa Torawarete Shimatta! (Disc 1) さなえチャンは囚われてしまった! | PC | | Original | | | |
| San Francisco Rush The Rock: Alcatraz Edition | PC | | Bundle Version Quantum3D OEM | | 740-0033-01 #QM049 | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | 170121 | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | | |
| Samurai Shodown II Samurai Spirits | PC | | All You Can Play: 10 Action-Games | | | |
| Samurai Shodown II Samurai Spirits | PC | | Original | | | |
| Samorost 2 | PC | | Machinarium + Samorost 2 | | | |
| Sammy Soza Softball Slam | PC | | Original | | PCD-5048-001 | |
| Sammy 3D Jump 'n' Fun: Gold Edition | PC | 1.02 | Original | | 11022 | |
| Samantha Swift and the Roses of Athena | PC | | Play + Smile | | | |
| Samantha Swift and the Golden Touch Samantha Swift Bundle | PC | | Original | | | |
| Samanta Svift. Tajna Zolotogo Prikosnoveniya Саманта Свифт. Тайна Золотого Прикосновения | PC | 1.2 | Original | | | |
| Samanta Svift. Tajna Atlantidy' Саманта Свифт. Тайна Атлантиды | PC | 1.3 | Original | | | |
| Sam & Max Hit the Road | PC | | Original | | 634031 | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives: Adventure Collection | | | |
| Sam & Max Hit the Road | PC | | Rerelease, The LucasArts Archives Vol. I | | 634430 | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives Vol. I | | | |
| Sam & Max Hit the Road | PC | | Original | | 634430 | |
| Sam & Max Hit the Road | PC | | LucasArts Classic | | 41117.101.IT | |
| Sam & Max Hit the Road | PC | | Collezione CD-Rom by C.T.O. | | | |
| Sam & Max Hit the Road | PC | 1.0 | LucasArts Classic | | 41117.101.GM | |
| Sam & Max Hit the Road | PC | | Softgold, Rerelease | | | |
| Sam & Max Hit the Road | PC | 2.0 | LucasArts Classic | | 41117.101.UK | |
| Sam & Max Hit the Road | PC | | Kixx XL | | | |
| Sam & Max Hit the Road | PC | | White Label: Doubles | | | |
| Sam & Max Hit the Road | PC | | LucasArts Classic | | 41117.101.AU | |
| Salvage Yard Simulator | PC | | Original | | | |
| Salt Lake 2002 | PC | | Original | | MSALTPGE81 | |
| Salt Lake 2002 | PC | 1.0 | Original | | MSALTPEN81 | |
| Sali Mali 123 | PC | 2.0 Build 216 | Original | | TPPC27 | |
| Salaryman Kintarou: Dai-3-kan Touhoku Dotou-hen サラリーマン金太郎:第3巻東北怒涛篇 | PC | | Original | | | |
| Salaryman Kintarou: Dai-2-kan Netsuai Roman-hen サラリーマン金太郎 第2巻 熱愛浪漫篇 | PC | | Original | | SCR90403 | |
| Salaryman Kintarou サラリーマン金太郎 | PC | | Original | | SCR90402 | |
| Salad Days: Shin Seitouha Ren'ai Typing サラダデイズ 新・正統派恋愛タイピング | PC | | Original | | | |
| Sakura Taisen: Denmaku Club 2 サクラ大戦 電幕倶楽部2 | PC | | Gouka Genteiban | | 673-01444 | |
| Sakura Taisen Monogatari: Mysterious Paris: Special Disc サクラ大戦物語 ~ミステリアス巴里~ Special Disc | PC | | Promo | | | |
| Sakura Taisen 3: Paris wa Moeteiru ka: Desktop Accessories サクラ大戦3 ~巴里は燃えているか~ デスクトップアクセサリーズ | PC | | Tokubetsu Genteiban B | | DWWWC-50121~50123 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 6) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03916 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 5) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03915 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 4) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03914 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 3) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03913 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 2) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03912 | |
| Sakura Taisen 3: Paris wa Moeteiru ka (Disc 1) サクラ大戦3 ~巴里は燃えているか~ | PC | | Shokai Genteiban | | 673-03911 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Install Disc 4) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | 1.0.0.0 | Original, Shokai Genteiban | | 673-02560 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Install Disc 5) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | 1.0.0.0 | Original, Shokai Genteiban | | 673-02561 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Install Disc 1) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02557 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Install Disc 2) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02558 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Install Disc 3) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02559 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Play Disc 1) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02554 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Play Disc 2) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02555 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Play Disc 3) サクラ大戦2 ~君、死にたもうことなかれ~ | PC | | Shokai Genteiban | | 673-02556 | |
| Sakura Taisen (Disc 3) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00192, 673-01921 | |
| Sakura Taisen (Disc 2) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00191, 673-01920 | |
| Sakura Taisen (Disc 1) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00190, 673-01919 | |
| Saints of Virtue | PC | 1.1 | Original | | | |
| The Saint: Abgrund der Verzweiflung | PC | | Original | | | |
| Saint Seiya: Typing Ryuuseiken 聖闘士星矢 タイピング流星拳 | PC | | Original | | | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Saint Eyes セイントアイズ | PC | | TGL-2000 Series | | | |
| Saint Eyes セイントアイズ | PC | | Shokai Genteiban | | | |
| Sailing: Baltic Sea Под Парусом: Балтика и Северное море | PC | | Original | | | |
| Saikyou Densetsu: Mahjong Haou 2: Kanzenban 最強伝説 麻雀覇王2 完全版 | PC | 1.04 | Best Selections | | | |
| Die Sage von Nietoom | PC | | Original | | | |
| The Sagara Family (Game Disc) | PC | | Original | | GC-026 | |
| The Sagara Family (Install Disc) | PC | | Original | | GC-026 | |
| Saga: Rage of the Vikings | PC | | Covermount | | | |
| Saga The Settlers I-IV (The Settlers III: Złota Edycja - Disc 1) | PC | 1.60 | eXtra Klasyka XK Gold | | | |
| Saga The Settlers I-IV (The Settlers III: Złota Edycja - Disc 2) | PC | 1.60 | eXtra Klasyka XK Gold | | | |
| Saga The Settlers I-IV (The Settlers I + II) | PC | | eXtra Klasyka XK Gold | | | |
| The Saga of Ryzom (Disc 2) | PC | | Original | | 75402104/2 | |
| The Saga of Ryzom (Disc 1) | PC | | Original | | 75402104/1 | |
| Saga Heroes of Might and Magic I-III (Disc 2) (Heroes of Might and Magic III) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Disc 1) (Heroes of Might and Magic III) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Heroes of Might and Magic) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Heroes of Might and Magic II) | PC | | eXtra Klasyka Next | | | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.01 | Original | | PCO519CD | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.0 | Original | | PCO519CD | |
| Safecracker Safecracker: L'avventura definitiva per aspiranti scassinatori | PC | 1.01 | Original | | SAFEMULTICD1 | |
| Safari Hunter: Safari Hunt Challenge | PC | 1.00 | Microforum | | | |
| Sado Gurumi no Machi: Tada de JK ni Nama Hame Dekiru to Omottara Shasei Shisugite Konsui Joutai ni Natta サドぐるみの町 ~タダでJKに生ハメ出来ると思ったら射精しすぎて昏睡状態になった~ | PC | 1.0.0.0 | Original | | SEA-097 | |
| Saddle Up: Time to Ride | PC | 1.00.000 | Original | | DPV1.0, PCO437CD | |
| Saddle Up with Pippa Funnell: Equestrian Champion | PC | | Original | | 782650-CF | |
| The Saddle Club: Willowbrook Stables (Disc 2) (Play) | PC | | Original | | IRG-SCWB | |
| The Saddle Club: Willowbrook Stables (Disc 1) (Install) | PC | | Original | | IRG-SCWB | |
| Sacrifice | PC | 0506.11.09 | Original | | CD-C95-1041-IT | |
| Sacred: La leggenda dell'Arma Sacra (Disco 1) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| Sacred: La leggenda dell'Arma Sacra (Disco 2) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| The Sacred Rings (Disc 4) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 3) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 2) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 1) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Mirror of Kofūn (Disc 3) | PC | | | | CKOF1096-3A | |
| The Sacred Mirror of Kofūn (Disc 2) | PC | | | | CKOF1096-2A | |
| The Sacred Mirror of Kofūn (Disc 1) (Installation) | PC | | | | CKOF1096-1A | |
| The Sacred Amulet | PC | | Original | | | |
| Sabrina the Teenage Witch: Spellbound | PC | 1.0c | Original | | S03836 | |
| Sabrina the Teenage Witch: Brat Attack | PC | | Original | | S02560 | |
| Sabre Ace: Konflict über Korea | PC | | Original | | | |
| Sabre Ace: Conflict over Korea | PC | 1.0 | Original | | D83115 | |
| Sabre Ace: Conflict over Korea | PC | | Original | | | |
| Sabotain: Break the Rules (Disc 2) Sabotain: Rúgd Fel a Szabályokat | PC | | Original | | SBT0000S60098075 | |
| Sabotain: Break the Rules (Disc 1) Sabotain: Rúgd Fel a Szabályokat | PC | | Original | | SBT0000S60098074 | |
| Sabotage: Break the Rules (Disc 2) Саботаж: Кулак Империи | PC | 1.0 | Original | | | |
| Sabotage: Break the Rules (Disc 1) Саботаж: Кулак Империи | PC | 1.0 | Original | | | |
| Saban's Power Rangers: Time Force | PC | | PC Fun Club | | PFC024/D | |
| Saban's Power Rangers: Time Force | PC | | Original | | | |
| Saban's Power Rangers Zeo Versus the Machine Empire | PC | | Original | | | |
| S³: Silent Storm: Sentinels | PC | 1.1 | Gold Edition | | | |
| S³: Silent Storm: Sentinels | PC | | Gold Edition | | ROSILENTST0004lab, ROSILENTST0006lab3 | |
| S²: Silent Storm (Disc 2) | PC | 1.1 | Gold Edition | | ROSILENTST0007lab2 | |
| S²: Silent Storm (Disc 2) | PC | 1.0 | Original | | 28015-CD2 | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | Gold Edition | | | |
| S²: Silent Storm (Disc 1) | PC | 1.0 | Original | | 28015-CD1 | |
| S²: Silent Storm (Disc 2) | PC | 1.1 | | | | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | | | | |
| S²: Silent Storm (Disc 2) | PC | 1.2 | Original | | ROSILENTST0011lab2 | |
| S²: Silent Storm (Disc 1) | PC | 1.2 | Original | | ROSILENTST0011lab1 | |
| S²: Silent Storm (Disc 2) | PC | 1.1 | Original | | JW002243 | |
| S²: Silent Storm (Disc 2) | PC | | Gold Edition | | ROSILENTST0006lab2 | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | Original | | JW002243 | |
| S²: Silent Storm (Disc 1) | PC | | Gold Edition | | ROSILENTST0006lab1 | |
| S²: Silent Storm (Disc 1) | PC | | Gold Edition | | ROSILENTST0007lab1 | |
| S.W.I.N.E. (Disc 2) (Play CD) | PC | 1.3 | Original | | AUT 180-2 | |
| S.W.I.N.E. (Disc 1) (Install CD) | PC | 1.3 | Original | | AUT 180-1 | |
| S.T.O.R.M. (Disc 3) | PC | | Original, Dice | | A541W3GD[3], DMM 031730 | |
| S.T.O.R.M. (Disc 2) | PC | | Original, Dice | | A541W3GD[2], DMM 031730 | |
| S.T.O.R.M. (Disc 1) | PC | | Original | | A541W3GD[1] | |
| S.T.O.R.M. (Disc 1) | PC | | Dice | | DMM 031730 | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Clear Sky (Płyta Dodatkowa) S.T.A.L.K.E.R.: Czyste Niebo | PC | | Original | | P_33142_02A_PL | |
| S.T.A.L.K.E.R.: Clear Sky (Assets) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Call of Pripyat (Soundtrack CD) | PC | | Special Edition | | | |
| S.S.D.S.: Setsuna no Akogare S.S.D.S. ー刹那の英雄- | PC | | Original | | | |
| S.O.E.: Operation Avalanche | PC | | EMCx: Gli Imperdibili | | | |
| S!Zone for SimCity 2000 | PC | | Original | | | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8V-EUR-B0 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8V-SCN-E0 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8X-LTN-E0 | |
| Skylanders: Swap Force | WII | | Starter Pack | | RVL-SVXX-LTN-E0 | |
| Swing Golf Pangya 2nd Shot! 스윙골프 팡야 2nd 샷! | WII | | Original | | RVL-R2PK-KOR | |
| Swing Golf Pangya 2nd Shot! スイングゴルフ パンヤ 2ndショット! | WII | | Original | | RVL-R2PJ-JPN | |
| Suzumiya Haruhi no Heiretsu 涼宮ハルヒの並列 | WII | | Original | | RVL-R44J-JPN | |
| Supervivientes | WII | | Original | | RVL-RV7S-ESP | |
| Super Truck Racer | WII | | Original | | RVL-SN7P-EUR-B0 | |
| Super Sentai Battle: Ranger Cross スーパー戦隊バトル レンジャークロス | WII | | Original | | RVL-SRJJ-JPN-B0 | |
| Super Robot Taisen Neo スーパーロボット大戦ネオ | WII | | Original | | RVL-RRWJ-JPN-B0 | |
| Super Monkey Ball: Uki Uki Party Daishuugou スーパーモンキーボール ウキウキパーティー大集合 | WII | | Original | | RVL-RSMJ-JPN | |
| Super Monkey Ball: Step & Roll | WII | | Original | | RVL-SMBE-USA-B0 | |
| Super Monkey Ball: Step & Roll | WII | | Original | | RVL-SMBP-EUR-B0 | |
| Super Monkey Ball: Banana Blitz | WII | | Original | | RVL-RSME-USA | |
| Super Monkey Ball: Banana Blitz | WII | | Original | | RVL-RSMP-EUR | |
| Super Monkey Ball Athletic スーパーモンキーボール アスレチック | WII | | Original | | RVL-SMBJ-JPN-B0 | |
| Super Mario Wii: Galaxy Adventure 슈퍼 마리오 Wii 갤럭시 어드벤처 | WII | | Original, Nintendo Selects | | RVL-RMGK-KOR, RVL-RMGK-KOR-B0 | |
| Super Mario Wii 2: Galaxy Adventure Together 슈퍼 마리오 Wii 2 갤럭시 어드벤처 투게더 | WII | | Original | | RVL-SB4K-KOR-B0 | |
| Super Mario Stadium: Family Baseball スーパーマリオスタジアム ファミリーベースボール | WII | | Original | | RVL-RMBJ-JPN | |
| Super Mario Galaxy 2 超級瑪利歐銀河2 | WII | | Original | | RVL-SB4W-CHT-B0 | |
| Super Mario Collection 슈퍼 마리오 컬렉션 | WII | | Super Mario Bros. 25th Anniversary | | RVL-SVMK-KOR-B0 | |
| Super Mario Collection スーパーマリオコレクション | WII | | Original | | RVL-SVMJ-JPN-B0 | |
| Super Mario All-Stars | WII | | Original, Nintendo Selects | | RVL-SVME-USA-B0 | |
| Super Mario All-Stars | WII | | Original, 25th Anniversary Edition | | RVL-SVMP-EUR-B0 | |
| Super Karts | WII | | Original | | RVL-SN6P-EUR-B0 | |
| Super Karts | WII | Rev 1 | Original | | RVL-SN6P-EUR-B0 | |
| Super Fruit Fall | WII | | Original | | RVL-RF4E-USA | |
| Super Fruit Fall | WII | | Original | | RVL-RF4P-UKV | |
| Summer Stars 2012 | WII | | Original | | RVL-SSJE-USA-B0 | |
| Summer Stars 2012 | WII | | Original | | RVL-SSJP-EUR-B0 | |
| Summer Sports: Paradise Island | WII | | Original | | RVL-RSUE-USA | |
| Summer Sports Party | WII | | Original | | RVL-RI6P-EUR | |
| Summer Sports 2: Island Sports Party | WII | | Original | | RVL-RI6E-USA-B0 | |
| Summer Challenge: Athletics Tournament | WII | | Original | | RVL-RE6P-EUR-B0 | |
| Summer Athletics: The Ultimate Challenge | WII | | Original | | RVL-RU3E-USA, RVL-RU3E-USA-B0 | |
| Summer Athletics 2009 | WII | | Original | | RVL-R9MP-EUR-B0 | |
| Summer Athletics | WII | Rev 1 | Original | | RVL-RUMP-EUR | |
| Summer Athletics | WII | | Original | | RVL-RUMP-EUR | |
| Sukeban Shachou Rena Wii: Neko Shachou, Tsukaeru Shain Daiboshuu. 女番社長レナWii 猫社長、つかえる社員大募集。 | WII | | Original | | RVL-R4YJ-JPN-B0 | |
| Sugoro Chronicle: Migite ni Ken o Hidarite ni Saikoro o スゴロクロニクル ~右手に剣を左手にサイコロを~ | WII | | Original | | RVL-RDUJ-JPN | |
| Sudoku Ball: Detective | WII | | Original | | RVL-R9SP-EUR | |
| Stunt Flyer: Hero of the Skies | WII | | Original | | RVL-SSTP-EUR-B0 | |
| Het Studio 100 Speeleiland | WII | | Original | | RVL-SPWH-HOL-B0 | |
| Street Football | WII | | Original | | RVL-R8KP-EUR-B0 | |
| Storybook Workshop | WII | | Original | | RVL-R4VE-USA-B0 | |
| Story Hour: Fairy Tales | WII | | Original | | RVL-R4FE-USA | |
| Story Hour: Fairy Tales | WII | | Original | | RVL-R4FP-EUR | |
| Story Hour: Adventures | WII | | Original | | RVL-R3AE-USA | |
| Story Hour: Adventures | WII | | Original | | RVL-R3AP-EUR | |
| Step to the Beat | WII | | Original | | RVL-RY6P-EUR-B0 | |
| Star Wars: The Force Unleashed II | WII | | Original | | RVL-SFUE-USA-B0 | |
| Star Wars: The Force Unleashed II | WII | | Original | | RVL-SF2P-EUR-B0 | |
| Star Wars: The Force Unleashed II | WII | | Beta | | | |
| Star Wars: The Force Unleashed | WII | | Original | | RVL-RSTE-USA, RVL-RSTE-USA-B0 | |
| Star Wars: The Force Unleashed スター・ウォーズ フォース アンリーシュド | WII | | Original | | RVL-RSTJ-JPN | |
| Star Wars: The Force Unleashed | WII | | Original | | RVL-RSTP-EUR | |
| Star Wars: The Clone Wars: Republic Heroes | WII | | Original | | RVL-RQLE-USA-B0 | |
| Star Wars: The Clone Wars: Republic Heroes | WII | | Original | | RVL-RQLP-EUR-B0 | |
| Star Wars: The Clone Wars: Lightsaber Duels | WII | | Original | | RVL-RLFE-USA, RVL-RLFE-USA-B0 | |
| Star Wars: The Clone Wars: Lightsaber Duels | WII | | Original | | RVL-RLFP-EUR | |
| Star Trek: Conquest | WII | | Original | | RVL-RTJE-USA | |
| Star Trek: Conquest | WII | | Original | | RVL-RTJP-EUR | |
| Squeeballs Party | WII | | Original | | RVL-R6YE-USA-B0 | |
| Squeeballs Party | WII | | Original | | RVL-R6YP-EUR-B0 | |
| Spy Games: Elevator Mission | WII | | Original | | RVL-RECE-USA-B0 | |
| Sprint Cars | WII | | Original | | RVL-SN8P-EUR-B0 | |
| Sports Party | WII | | Original | | RVL-RSUP-UKV, RVL-RSUP-UKV-B0 | |
| Sports Island 3 | WII | | Original | | RVL-S3DP-EUR-B0 | |
| Sports Island 2 | WII | | Original | | RVL-R2SP-EUR-B0 | |
| Sports Island | WII | | Original | | RVL-RDXP-EUR | |
| Spore: Kimi ga Tsukuru Hero スポア キミがつくるヒーロー | WII | | Original | | RVL-RQOJ-JPN-B0 | |
| The Spirit of the Wolf | WII | | Original | | RVL-SLPP-EUR-B0 | |
| The Spiderwick Chronicles | WII | | Original | | RVL-R48E-USA | |
| The Spiderwick Chronicles | WII | | Original | | RVL-R48P-EUR | |
| Spider-Man: Shattered Dimensions | WII | | Original | | RVL-SPDE-USA-B0 | |
| Spider-Man: Shattered Dimensions | WII | | Original | | RVL-SPDP-EUR-B0 | |
| Spider-Man: Edge of Time | WII | | Original | | RVL-SQME-USA-B0 | |
| Spider-Man: Edge of Time | WII | | Original | | RVL-SQMP-EUR-B0 | |
| Spellbound Party | WII | | Original | | RVL-SPBP-EUR-B0 | |
| Speed Racer: The Videogame | WII | | Original | | RVL-R3PE-USA | |
| Speed Racer: The Videogame | WII | | Original | | RVL-R3PP-EUR | |
| Spectrobes: Origins | WII | | Original | | RVL-RXXE-USA-B0 | |
| Spectrobes: Origins | WII | | Original | | RVL-RXXP-EUR-B0 | |
| Spaghetti Western Shooter | WII | | Original, Bundled with Wii Gun | | RVL-SPHP-EUR-B0 | |
| Space Station Tycoon | WII | | Prototype | | | |
| Soul Eater: Monotone Princess ソウルイーター モノトーン プリンセス | WII | | Original | | RVL-RSEJ-JPN | |
| Sonic World Adventure ソニック ワールドアドベンチャー | WII | | Original | | RVL-RSVJ-JPN | |
| Sonic to Himitsu no Ring ソニックと秘密のリング | WII | | Original | | RVL-RSRJ-JPN | |
| Sonic to Himitsu no Ring ソニックと秘密のリング | WII | | Taikenban | | RVL-DSRJ-JPN | |
| Sonic to Ankoku no Kishi ソニックと暗黒の騎士 | WII | | Original | | RVL-RENJ-JPN | |
| Sonic Riders: Zero Gravity | WII | | Original | | RVL-RS9E-USA | |
| Sonic Riders: Zero Gravity | WII | | Original | | RVL-RS9P-EUR | |
| Sonic Riders: Shooting Star Story ソニックライダーズ シューティングスターストーリー | WII | | Original | | RVL-RS9J-JPN | |
| Sonic and the Secret Rings | WII | | Original, Target Exclusive | | RVL-RSRE-USA | |
| Sonic and the Secret Rings | WII | | Original | | RVL-RSRP-EUR, RVL-RSRP-EUR-B0 | |
| Sonic and the Black Knight | WII | | Original | | RVL-RENE-USA, RVL-RENE-USA-B0 | |
| Sonic and the Black Knight | WII | | Original | | RVL-RENP-EUR | |
| Sonic & Sega All-Stars Racing | WII | | Original | | RVL-R3RE-USA-B0 | |
| Sonic & Sega All-Stars Racing | WII | | Original, Bundled with Wii Game Plus Racing Wheel | | RVL-R3RP-EUR-B0 | |
| Solitaire & Mahjong | WII | | Original | | RVL-RSOE-USA-B0 | |
| So Blonde: Back to the Island | WII | | Original | | RVL-RVJP-EUR-B0 | |
| Sniper Elite | WII | | Original | | RVL-SSNE-USA-B0 | |
| Sniper Elite | WII | | Original | | RVL-SSNP-EUR-B0 | |
| The Smurfs: Dance Party | WII | | Original | | RVL-SDUE-USA-B0 | |
| The Smurfs: Dance Party | WII | | Toys R Us | | RVL-SDUX-USA-B0 | |
| The Smurfs: Dance Party | WII | | Original | | RVL-SDUP-EUR-B0 | |
| The Smurfs Party Pack | WII | | Original | | RVL-S7SP-EUR-B0 | |
| The Smurfs 2 | WII | | Original | | RVL-S2XE-USA-B0 | |
| The Smurfs 2 | WII | | Original | | RVL-S2XP-EUR-B0 | |
| Smarty Pants: Trivia Fun for Everyone! | WII | | Original | | RVL-RP2E-USA | |
| Smarty Pants: Trivia Fun for Everyone! | WII | | Original | | RVL-RP2P-FRA, RVL-RP2P-NOE | |
| Smart Series Presents: Jaja's Adventure | WII | | Original | | RVL-R67E-USA-B0 | |
| Sleepover Party | WII | | Original | | RVL-R9LE-USA-B0 | |
| Sled Shred featuring the Jamaican Bobsled Team | WII | | Original | | RVL-R9YE-USA-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8E-USA-B1 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8E-USA-B0 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8P-EUR-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8I-EUZ-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8P-EUR-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8D-FAH-B0 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8I-EUZ-B0 | |
| Skylanders: Trap Team | WII | | Starter Pack | | RVL-SK8D-FAH-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPE-USA-B1 | |
| Skylanders: Spyro's Adventure | WII | | Starter Pack | | RVL-SSPE-USA-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPX-SCN-B2 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPX-SCN-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPX-SCN-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPP-EUR-B2 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPP-EUR-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPP-EUR-B0 | |
| Skylanders: Spyro's Adventure | WII | | Starter Pack | | RVL-SSPY-BRA-B0 | |
| Skylanders: Giants | WII | | Starter Pack | | RVL-SKYE-USA-B0 | |
| Skylanders: Giants | WII | | Starter Pack | | RVL-SKYX-SCN-B0 | |
| Skylanders: Giants | WII | | Booster Pack | | RVL-SKYZ-EUZ-B0 | |
| Skylanders: Giants | WII | | Starter Pack | | RVL-SKYP-EUR-B0 | |
| Skylanders: Giants | WII | | Starter Pack | | RVL-SKYY-USA-B0 | |