Region | Title | System | Version | Edition | Languages | Serial | Status |
| Z and Z Expansion Kit | PC | | Original | | | |
| Z and Z Expansion Kit | PC | | Original | | | |
| Zanac x Zanac ザナック×ザナック | PSX | | Original | | SLPS 03354 | |
| Zanac x Zanac ザナック×ザナック | PSX | | Taikenban | | SLPM 80626 | |
| Zap! Snowboarding Trix ザップ! スノーボーディング・トリックス | PSX | | Fukyuuban 1500 | | SLPS 03034 | |
| Zap! Snowboarding Trix '98 ザップ! スノーボーディング・トリックス’98 | PSX | | Original | | SLPS 00909 | |
| Zapitalism! Deluxe | PC | | Original | | | |
| Zapitalism! Deluxe | PC | | | | | |
| Zax: The Alien Hunter | PC | | Original | | ROZAX00003LAB, ROZAX00005LAB | |
| Zegapain XOR ゼーガペイン XOR | XBOX360 | | Original | | BA-2001 | |
| Zehn Adventures: Die Adventure Spielesammlung (Disc 2) Sam & Max Hit the Road | PC | | Original, Rerelease | | | |
| Zen Nihon GT Senshuken Max Rev. (Disc 1) 全日本GT選手権 MAX Rev. | PSX | | Original | | SLPS 00715 | |
| Zen Nihon GT Senshuken Max Rev. (Disc 2) 全日本GT選手権 MAX Rev. | PSX | | Original | | SLPS 00716 | |
| Zen Nihon Joshi Pro Wres: Queen of Queens (Disc A) (Zenjo vs Zenjo) 全日本女子プロレス クイーン・オブ・クイーンズ | PC-FX | | Original | | FXNHE503 | |
| Zen Nihon Joshi Pro Wres: Queen of Queens (Disc B) (Zenjo vs KWP) 全日本女子プロレス クイーン・オブ・クイーンズ | PC-FX | | Original | | FXNHE503 | |
| Zeneca Pharmaceuticals Group: Experts in Anti-Infectives: Pathogen Pursuit: An Interactive Medical Program | CDI | | Original | | | |
| Zero Divide 2: The Secret Wish ゼロ・ディバイド2 ~ザシークレットウィッシュ~ | PSX | | Taikenban | | PCPX 96081 | |
| Zhongguo Anqi Zhi Zongheng Tianxia 中國暗棋之縱橫天下 | PSX | | Unlicensed (Demo) | | | |
| Zhongguo Xiangqi: The 10 Games 中國象棋 The 10 Games | PC | | Original | | | |
| Zloj, ploxoj i trezvyj Злой, плохой и трезвый | PC | | Original | | | |
| Zoids Infinity EX Neo ゾイドインフィニティEX NEO | XBOX360 | | Original | | TO-2001 | |
| Zoku Hatsukoi Monogatari: Shuugaku Ryokou (Disc 1) 続初恋物語 ~修学旅行~ | PC-FX | | Original | | FXNHE629 | |
| Zoku Hatsukoi Monogatari: Shuugaku Ryokou (Disc 2) 続初恋物語 ~修学旅行~ | PC-FX | | Original | | FXNHE629 | |
| Zoo Hospital | WII | | Original | | RVL-RZHX-EUR | |
| Zoo Tycoon | PC | | Original | | 0801 Artikelnr. X08-36547 DE | |
| Zoo Tycoon | PC | | Original | | 0801 Artikelnr. X08-36547 DE | |
| Zoo Tycoon | PC | | Zoo Tycoon: Complete Collection (Rerelease), Zoo Tycoon: Complete Collection (Xplosiv) | | 0803 Part No. X10-10290, P/N: 111489, XP-2233-1 ML03 | |
| Zoo Tycoon 2 ズー タイクーン 2 | PC | | Original | | 1004 Part No.X10-90499 | |
| Zoo Tycoon 2: Marine Mania | PC | | Original | | 0706 Part No. X12-79927-01 | |
| Zoo Tycoon 2: Marine Mania | PC | | Original | | 0706 Part No. X12-79927-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 1) | PC | | Original | | 0806 Part No. X12-80044-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 2) | PC | | Original | | 0806 Part No. X12-80045-01 | |
| Zoo Tycoon: Dinosaur Digs | PC | | Original | | 0302 Artikelnr. X08-69362 DE, 0303 Artikelnr. X09-60984 DE | |
| Zoo Tycoon: Dinosaur Digs | PC | | Original | | 0302 Part No. X08-63367 | |
| Zoo Tycoon: Marine Mania | PC | | Original | | 0902 Artikelnr. X09-00521 DE | |
| Zoo Tycoon: Marine Mania & Dinosaur Digs Zoo Tycoon Expanded | PC | | Original | | 0802 Part No. X08-90495 | |
| Zoo Tycoon: Marine Mania & Dinosaur Digs | PC | | Zoo Tycoon: Complete Collection, Zoo Tycoon: Complete Collection (Xplosiv) | | 0803 Part No. X10-10291, P/N: 111500, XP-2233-2 ML03 | |
| Zool: Ninja of the "Nth" Dimension / Zool 2 Maxx Out Double Play CD-ROM | PC | | Original | | CN 000500021 | |
| Zozo Mix 1/2008 | PC | | | | | |
| Zozo Mix 3/2008 | PC | | | | | |
| Zozo Mix 5/2008 | PC | | | | | |
| Zumba Fitness 2 | WII | | Original | | RVL-SZ2X-EUR-B0 | |
| Zumba Fitness Core | WII | | Original | | RVL-SU6X-EUZ-B0 | |
| ZXE-D: Legend of Plasmatlite ゼクシード | PSX | | Original | | SLPS 00424 | |
| Z/X: Zekkai no Crusade Z/X 絶界の聖戦 | PS3 | 01.03 | Original | | BLJS 10195 | |
| Zapper Zapper: One Wicked Cricket! | PC | 1.0 | Scholastic | | Part # CDR9-57451-X | |
| Zhijixing (Disc 1) (Yi) 指极星 | PC | 1.0 | Original | | | |
| Zhijixing (Disc 2) (Er) 指极星 | PC | 1.0 | Original | | | |
| Zoo Tycoon: Dinosaur Digs | PC | 1.0 | Original | | 0302 Part No. X08-63367 | |
| Zootrix | PC | 1.0 | Original | | 5373 | |
| Zuma Deluxe 祖玛 | PC | 1.0 | Original | | | |
| Zuma Deluxe | PC | 1.0 | Game of the Year | | | |
| Zuma Deluxe | PC | 1.0 | Rerelease | | | |
| Zuma Deluxe | PC | 1.0 | Game of the Year | | | |
| Zak: Oxotnik s chuzhoj planety Зак: Охотник с чужой планеты | PC | 1.0 Build 1308 | Original | | RUSSOBIT-M 153/2001 | |
| Zagadki Nostradamusa: V poiskax kol'ca Sud'by Загадки Нострадамуса: В поисках кольца Судьбы | PC | 1.0.0.4 | 1C: Igrushki | | | |
| Zoo Tycoon 2: African Adventure | PC | 1.00.0000 | Original | | 0206 Part No. X12-15023-01 | |
| Zenkoku Seifuku Bishoujo Grand Prix: Find Love 全国制服美少女グランプリ ファインドラブ | SS | 1.000 | Original | | T-34602G | |
| Zap! Snowboarding Trix '98 ザップ! スノーボーディング・トリックス’98 | SS | 1.001 | Original | | T-7504G | |
| Zap! Snowboarding Trix ザップ! スノーボーディング・トリックス | SS | 1.003 | Original | | T-7502G | |
| Zanzarah: V poiskax zateryannoj strany Zanzarah: В поисках затерянной страны | PC | 1.008 | Original | | RUSSOBIT-M 2003 / 356 | |
| Zhanshen III: Yingxiong Wangchao 战神Ⅲ:英雄王朝 | PC | 1.02 | Original | | | |
| Zemlya myortvyx: Doroga k Fiddlerz Grin (Disc 1) Земля мёртвых: Дорога к Фиддлерз Грин | PC | 1.1 | Original | | | |
| Zemlya myortvyx: Doroga k Fiddlerz Grin (Disc 2) Земля мёртвых: Дорога к Фиддлерз Грин | PC | 1.1 | Original | | | |
| Zoo Tycoon | PC | 10.10.00.0006 | Original | | 0801 Part No. X08-30526 | |
| Zoo Tycoon | PC | 10.10.00.0006 | Original | | 0801 Parte n. X08-36552 IT | |
| Zoo Tycoon ズー タイクーン | PC | 10.10.00.0006 | Original | | 1101 Part No. X08-58849 | |
| Zoo Tycoon 動物園大亨 | PC | 10.10.00.0006 | Original | | 1201 Part No. X08-56919 | |
| Zoo Tycoon | PC | 10.10.00.0006 | Original | | 0801 Part No. X08-30525 | |
| Zoo Tycoon | PC | 10.10.00.0009 | Zoo Tycoon: Complete Collection | | 0603 Part No. X09-79593, 0803 Part No. X10-10290 | |
| Zoo Tycoon: Complete Collection (Disc 1) (Zoo Tycoon) | PC | 10.10.00.009 | Original | | X10-10508 SV | |
| Zoo Tycoon: Complete Collection (Disc 2) (Marine Mania) | PC | 10.10.00.009 | Original | | X10-10510 SV | |
| Zoo Tycoon: Dinosaur Digs | PC | 11.05.00.0006 | Original | | 0302 Parte n. X08-69361 IT | |
| Zoo Tycoon: Marine Mania & Dinosaur Digs | PC | 12.04.00.0009 | Zoo Tycoon: Complete Collection | | 0603 Part No. X09-79601, 0803 Part No. X10-10291 | |
| Zoo Tycoon 2 | PC | 20.10.00.0026 | Original | | 0904 Pieza N° X10-75870 ES | |
| Zoo Tycoon 2 | PC | 20.10.00.0026 | Original | | 0804 Part No. X10-74059 | |
| Zoo Tycoon 2 | PC | 20.11.00.0007 | Rerelease | | 0804 Part No. X10-74059 | |
| Zoo Tycoon 2: Endangered Species | PC | 21.07.00.0011 | Original | | 0805 Pieza n° X11-46467 ES | |
| Zoo Tycoon 2: Endangered Species | PC | 21.07.00.0011 | Original | | 0705 Part No. X11-45794 | |
| Zoo Tycoon 2: African Adventure | PC | 22.03.00.0012 | Original | | 0406 Pieza n° X12-10595-01 ES | |
| Zoo Tycoon 2: Marine Mania | PC | 30.08.00.0009 | Original | | 0906 Pieza n° X12-88849-01 ES | |
| Zoo Tycoon 2: Extinct Animals | PC | 32.10.0.9 | Original | | 0707 Part No. X13-85741-01, X13-85741-01 | |
| Zoo Tycoon 2: Extinct Animals | PC | 32.10.00.0009 | Original | | 0807 Pieza n° X13-89080-01 ES | |
| Zoo Tycoon 2: Ultimate Collection (Disc 1) | PC | 33.05.00.0002UO | Original | | X15-01905-01 EN | |
| Zoo Tycoon 2: Ultimate Collection (Disc 2) | PC | 33.05.00.0002UO | Original | | X15-01906-01 EN | |
| Zoo Tycoon 2: Ultimate Collection (Disc 1) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72299-01 | |
| Zoo Tycoon 2: Ultimate Collection (Disc 2) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72305-01 | |
| Zoo Tycoon 2: Ultimate Collection (Disc 3) | PC | 33.05.00.0002UO | Original | | 0608 Part No. X14-72309-01, X15-01907-01 EN | |
| Zero Wing ゼロ・ウイング | PCE | Rev 8 | Original | | NXCD1003 | |