| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Spear of Destiny | PC | 1.4 | Original |  | |  |
| Spear of Destiny: Super CD Pack | PC | | Super CD Pack | | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Spec Ops II: U.S. Army Green Berets | PC | | Budget, BIS Collezione CD-ROM |     | 10019 | |
| Spec Ops II: U.S. Army Green Berets | PC | | Original | | | |
| Spec Ops: Rangers Lead the Way | PC | | SmartSaver | | 279446-CD | |
| Spec Ops: Rangers Lead the Way | PC | | Demo | | CD-RC008 | |
| Spec Ops: Rangers Lead the Way | PC | 1.0 | Original | | CD-RC008 | |
| Spec Ops: Rangers Lead the Way: Pro Pack | PC | Beta | | | | |
 | Speccy Classix | PC | | Rerelease | | | |
| Speccy Classix '98
Speccy Classix 1998 | PC | | | | | |
 | Special Disk Tryset Mix 12 | PC | | Pre-Order Bonus |  | | |
 | Specnaz: Operaciya Antiterror
Спецназ: Операция Антитеррор | PC | | 1C: Kollekciya igrushek |  | | |
 | Spectrobes: Beyond the Portals (Electronic Press Kit) | PC | | Press Kit | | | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speedway 2000 | PC | | Original | | | |
 | Speedway Championships | PC | | Original | | | |
 | Speedy Eggbert | PC | 1.1 | Original |  | 02-9703-10 | |
 | Speedy Eggbert II | PC | 1.0 | Original | | | |
| Speedy Eggbert II
Speedy Eggbert 2 | PC | 1.0 | Original | | | |
 | Speedy Zone 2 | PC | | Original | | 100-4045 | |
| Spellcasting: Party Pak | PC | | Original | | | |
 | SpellForce: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka |  | | |
| SpellForce: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 3) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 4) | PC | | Nowa eXtra Klasyka | | | |
| Spelling: 'SATS' Key Stage 2 | PC | 1999.12.1.1 | Original | | | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Spelvin Goolie Private Eyeball
Spelvin Goolie Private Eyeball: The World's Greatest Left-Handed Detective | PC | 1.0 | Original | | ROW-10942 | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| Spider-Man 2: Activity Center | PC | | Original | | 31925.101.US | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi
Ｓｐｉｎｎａｋｅｒ タイピングコレクション 鋼の錬金術師 | PC | 1.01 | Original | | | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi: Roy Ver.
Ｓｐｉｎｎａｋｅｒ Ｔｙｐｉｎｇ Ｃｏｌｌｅｃｔｉｏｎ 鋼の錬金術師 ロイｖｅｒ． | PC | | Original | | | |
| Spirits of Mystery: Amber Maiden | PC | | BlackLime Games | | BLG022/D | |
| Spiritual Soul 2: The Blue-Eyed Elementaler
スピリチュアル ソウル ２ ～蒼き瞳の精霊使い～ | PC | | Original | | | |
| Spokojnye igry: krug, shashki, shaxmaty, ugolki i...
Спокойные игры: круг, шашки, шахматы, уголки и... | PC | | Original | | | |
| Spooky Castle | PC | 1.0 | Original | | 11-2057-10 SPC | |
| Sporting Clays
スポーティング クレー | PC | | Original | | TORM-6257 | |
| Sporting Clays: Interactive Shooting Simulation | PC | 1.0 | Original | | P/N 7407 | |
| Sportowe Zmagania bez Wysiłku i Biegania | PC | | | | | |
| Sportsman's Double Play | PC | 1.0.0 | Original | | | |
| Sprill: Wodne Przygody | PC | | | | | |
| Springy | PC | | Original | | | |
| Spy Fox 2: "Some Assembly Required" | PC | 1.0.0.1 | Original | | Part No. 04-17571CD | |
 | Spy Fox 2: Operatie "Robot-Knop" | PC | | Original |  | | |
| Spy Fox 2: Operatie "Robot-Knop" | PC | | CD-ROM Toppers | | | |
| Spy Fox 2: Operatie "Robot-Knop"
Spy Fox: Operatie Robot-Knop | PC | 1.0.0.1 | Rerelease | | 04DSILK16n | |
| Spy Fox 3 in 1! | PC | | Original | | 04DSILK20a | |
| Spy Fox Duopack | PC | | Original | | 05DSILKS14 | |
| Spy Fox in "Cheese Chase" | PC | | Original | | | |
| Spy Fox in "Cheese Chase" | PC | 2.00 | Rerelease | | Part No. 04-15244CD | |
| Spy Fox in "Das Milchkartell" | PC | | Rerelease | | 1003163 | |
| Spy Fox in "Das Milchkartell" | PC | | Kellogg's | | | |
| Spy Fox in "Dry Cereal" | PC | | Rerelease | | 23563CD | |
| Spy Fox in "Dry Cereal" | PC | | Rerelease | | Part # 001407 | |
| Spy Fox in "Dry Cereal" | PC | | Rerelease | | Part # 0001407 | |
| Spy Fox in "Dry Cereal" | PC | | Demo | | | |
| Spy Fox in "Dry Cereal" | PC | 1.0 | Original | | 04-70281, Part # 0001407, Part No. 04-00000H1529 | |
| Spy Fox in "Dry Cereal" | PC | 2.00 | Original | | Part #04-00000H1407 | |
| Spy Fox in "Hold the Mustard" | PC | 1.0 | Original | | Part No. 04-17574CD | |
| Spy Fox in "Operation Robohund" | PC | 1.0.0.1 | Rerelease | | SPY2PCMCD/A | |
| Spy Fox in Operatie "Melk Weg" | PC | | Rerelease | | | |
| Spy Fox in Operatie "Melk Weg"
Spy Fox: Operatie Melkweg | PC | | Original | | | |
| Spy Fox in Operatie "Melk Weg"
Spy Fox: Operatie Melkweg | PC | | Taptoe | | 500634 | |
 | Spy Fox: "Operation Milkshake" | PC | | Kellogg's | | | |
 | Spy Fox: "Operation Milkshake" | PC | | Rerelease | | | |
| Spy Fox: "Operation Ozone" | PC | | Original | | | |
| Spy Fox: "Operation Ozone" | PC | | Original | | Part No. 04-22394CD | |
| Spy Fox: "Operation Ozone" | PC | | Rerelease | | pvaol008spyo | |
| Spy Fox: "Operation Ozone" | PC | | Original | | | |
| Spy Kids 3-D: Game Over | PC | | Original |       | I6100 | |
| Spy Kids Learning Adventures: The Candy Conspiracy | PC | | Original | | 03962 | |
| Spy Kids Learning Adventures: The Nightmare Machine | PC | | Original | | 03963 | |
| Spy Kids: Mega Mission Zone | PC | | Fun Family Games | | H3343 | |
| Spy Kids: Mega Mission Zone | PC | 3.6.27 | Original | | H3343 | |
| Spy Masters: Training Mission / JumpStart Music | PC | | Great Clips | | W0000946 | |
 | Spycraft: La Grande Sfida (Disc 1) | PC | | | | | |
| Spycraft: La Grande Sfida (Disc 2) | PC | | | | | |
| Spycraft: La Grande Sfida (Disc 3) | PC | | | | | |
| Spycraft: The Great Game (Disc 1) | PC | | Original | | CDD-3110-101-U3, CDD-3110-101-UK | |
| Spycraft: The Great Game (Disc 3) | PC | | Original | | CDD-3110-103-U3 | |
| Spycraft: The Great Game | PC | | Interactive Preview | | | |
| Spycraft: The Great Game (Disc 1) | PC | | Original | | CDD-3110-101-U3 | |
| Spycraft: The Great Game (Disc 3) | PC | | Original | | CDD-3110-103-U3 | |
 | Spycraft: The Great Game (Disc 2) | PC | | Original | | CDD-3110-102-U3 | |
| SpyHunter | PC | | Original | | 103201CDA, RUSSOBIT-M 2003/414 | |
| Spyro: A Hero's Tail (Assets) | PC | | Press Kit | | | |
| Square Enix: Final Fantasy VII Advent Children Trailer | PC | | Press Kit | | | |
| SRS: Street Racing Syndicate (Disc 1) | PC | | Serie Maxima | | | |
| SRS: Street Racing Syndicate (Disc 2) | PC | | Serie Maxima | | | |
| SRS: Street Racing Syndicate (Disc 1) | PC | | Original | | | |
| SRS: Street Racing Syndicate (Disc 2) | PC | | Original | | | |
| SSI Strategy Collection: Critic's Choice
Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| St. Cosplay Gakuen: Game Bunkou
聖（セント）コスプレ学園 ～ゲーム分校～ | PC | | Original | | SHD-00001 | |
| Stal'nye Samurai
Стальные самураи | PC | | Original | | RUSSOBIT-M 2003/345 | |
| Stalingrad: Wielkie Bitwy II Wojny Światowej (Disc 1)
Great Battles of WWII: Stalingrad | PC | | Original | | CENEGA 338a/2005 | |
| Stalingrad: Wielkie Bitwy II Wojny Światowej (Disc 2)
Great Battles of WWII: Stalingrad | PC | | Original | | CENEGA 338b/2005 | |
| Stanley's Sticker Stories | PC | 1.04 | Original | | 381428-CD4/I083ha | |
| Stanley's Verhalenhuis | PC | | Original | | NZEM016-97800A | |
| Star Academy | PC | | Original | | | |
| Star Academy: Le Nouveau Défi | PC | | Original | | | |
