Region | Title | System | Version | Edition | Languages | Serial | Status |
| S!Zone for SimCity 2000 | PC | | Original | | | |
| S.C.A.R.S. | PC | | Original | | | |
| S.C.A.R.S. | PSX | | Original | | SLUS-00692 | |
| S.L.A.I.: Steel Lancer Arena International S.L.A.I.: Phantom Crash | PS2 | 0.11 | Beta | | SLUS 29132 | |
| S.L.A.I.: Steel Lancer Arena International | PS2 | 1.02 | Original | | SLUS-20969 | |
| S.T.A.L.K.E.R.: Call of Pripyat | PC | 1.6.02 | Collector's Edition | | | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD950001D | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0 | Original | | 109310 | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | Gold Edition | | | |
| S²: Silent Storm (Disc 1) | PC | 1.2 | Original | | 28015-CD1 | |
| S²: Silent Storm (Disc 2) | PC | 1.2 | Original | | 28015-CD2 | |
| S³: Silent Storm: Sentinels | PC | 1.1 | Gold Edition | | | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| Saban's Power Rangers Zeo: Full Tilt Battle Pinball | PSX | | Original | | SLUS-00256 | |
| Saban's Power Rangers: Lightspeed Rescue | PSX | | Original | | SLUS-01114 | |
| Saban's Power Rangers: Time Force | PSX | | Original | | SLUS-01351 | |
| Sable Maze: Forbidden Garden & Twelve Fears | PC | | Original | | 33528010US | |
| Sable Maze: Sullivan River / Norwich Caves | PC | | | | 33471010US | |
| The Saboteur | PS3 | 01.00 | Original | | BLUS-30407 | |
| The Saboteur | PC | 1.0 | Original | | | |
| Sabre Ace | PC | 1.0 | Covermount | | | |
| Sabre Ace: Conflict over Korea | PC | 1.0 | Original | | D83115 | |
| Sabrina the Teenage Witch: A Twitch in Time! | PSX | | Original | | SLUS-01208 | |
| Sabrina the Teenage Witch: Brat Attack | PC | | Original | | S02560 | |
| Sabrina the Teenage Witch: Spellbound | PC | 1.0c | Original | | S03836 | |
| Sacra Terra: Angelic Night | PC | | Original | | | |
| Sacred (Disc 1) | PC | 1.2.0.10 | Original | | 28302-CD1 v1.0 | |
| Sacred (Disc 1) | PC | 1.8 | Rerelease | | 10153-CD1 | |
| Sacred (Disc 2) | PC | 1.2.0.10 | Original | | 28302-CD2 v1.0 | |
| Sacred (Disc 2) | PC | 1.8 | Rerelease | | 10153-CD2 | |
| Sacred 2 (Disc 1) | PC | | Original | | | |
| Sacred 2 (Disc 2) | PC | | Original | | | |
| Sacred 2: Fallen Angel | PS3 | 01.00 | Original | | BLUS-30312 | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| Sacred 3 | PS3 | 01.02 | Original | | BLUS-30876 | |
| The Sacred Amulet | PC | | Original | | | |
| Sacred Gold (Disc 1) | PC | 2.24 | Original | | 10130-CD1 | |
| Sacred Gold (Disc 2) | PC | 1.0 | Original | | 10130-CD2 | |
| Sacred Gold (Disc 3) | PC | 1.0 | Original | | 10130-CD3 | |
| The Sacred Mirror of Kofūn (Disc 1) (Installation) | PC | | | | CKOF1096-1A | |
| The Sacred Mirror of Kofūn (Disc 2) | PC | | | | CKOF1096-2A | |
| The Sacred Mirror of Kofūn (Disc 3) | PC | | | | CKOF1096-3A | |
| The Sacred Rings (Disc 1) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 2) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 3) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 4) | PC | 1.0 | Original | | PCO466CD | |
| Sacrifice (Editors Press Kit) | PC | | Press Kit | | | |
| Sacrifice (Scapex Tutorial Video) | PC | | Preproduction | | | |
| Sacrifice | PC | | Bundle Version Hewlett Packard OEM | | CD-C951041-PC2E | |
| Saddle Up with Pippa Funnell: Equestrian Champion | PC | | Original | | 782650-CF | |
| Saddle Up: Time to Ride | PC | 1.00.000 | Original | | DPV1.0, PCO437CD | |
| Safari Adventures: Africa | WII | | Original | | RVL-RFWE-USA-B0 | |
| Safecracker | WII | | Original | | RVL-RQFE-USA | |
| Safecracker | PC | | Rerelease | | | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.0 | Original | | PCO519CD | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.01 | Original | | PCO519CD | |
| SaGa Frontier | PSX | | Original | | SCUS-94230 | |
| SaGa Frontier 2 | PSX | | Original | | SLUS-00933 | |
| The Sagara Family (Game Disc) | PC | | Original | | GC-026 | |
| The Sagara Family (Install Disc) | PC | | Original | | GC-026 | |
| Sail 2000 | PC | 1.04 | Original | | | |
| Sail with Columbus | VIS | | Original | | 25-6181 | |
| Sailing | CDI | | Original, Demonstration Disc | | 310-690-101-2, 310690101-2 | |
| Saint | WII | | Original | | RVL-RZCE-USA-B0 | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Saints of Virtue | PC | 1.1 | Original | | | |
| Saints Row | XBOX360 | | Demo | | IM-2022 | |
| Saints Row 2 | PC | | Original | | | |
| Saints Row 2 | PS3 | 01.00 | Original, Greatest Hits | | BLUS-30201 … | |
| Saints Row IV | PS3 | 01.00 | Original, Commander in Chief Edition | | BLUS-31205 | |
| Saints Row IV: National Treasure Edition | PS3 | 01.01 | Greatest Hits | | BLUS-31416 … | |
| Saints Row: Gat out of Hell | PS3 | 01.00 | Original | | BLUS-31496 | |
| Saints Row: The Third (Disc 1) | PC | | Original | | | |
| Saints Row: The Third (Disc 2) | PC | | Original | | | |
| Saints Row: The Third: The Full Package | PS3 | 01.00 | Original | | BLUS-31062 | |
| Saiyuki: Journey West | PSX | | Original | | SLUS-01381 | |
| Sakura Wars: So Long, My Love | WII | | Original | | RVL-SAKE-USA-E0 | |
| Sakura Wars: So Long, My Love (Disc 1) (English Voice Over) | PS2 | 1.00 | Original | | SLUS 21927 | |
| Sakura Wars: So Long, My Love (Disc 2) (Japanese Voice Over) | PS2 | 1.00 | Original | | SLUS 21930 | |
| Salt Lake 2002 | PS2 | 1.01 | Original | | SLUS-20378 | |
| Saltwater Sportfishing | PSX | | Original | | SLUS-01397 | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives: Adventure Collection | | | |
| Sam & Max Hit the Road | PC | | Original | | 634031 | |
| Sam & Max Hit the Road | PC | | Original | | 634430 | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives Vol. I | | | |
| Sam & Max Hit the Road | MAC | | Original | | 8022133 | |
| Sam & Max Hit the Road | PC | | Rerelease, The LucasArts Archives Vol. I | | 634430 | |
| Sam & Max: Beyond Time and Space | PC | | Original | | 27898CD | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YE-USA-B0 | |
| Sam & Max: Season One | WII | | Beta | | | |
| Sam & Max: Season One | WII | | Original | | RVL-R3XE-USA | |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| Samantha Swift and the Golden Touch Samantha Swift Bundle | PC | | Original | | | |
| Samba de Amigo | WII | | Original | | RVL-R3BE-USA | |
| Samba de Amigo | DC | 1.001 | Original | | 51092 | |
| Same or Different | PC | | Book Bundle | | 08028 | |
| Sammy Sosa High Heat Baseball 2001 | PSX | | Original | | SLUS-01063 | |
| Sammy Sosa Softball Slam | PSX | | Original | | SLUS-01064 | |
| Sammy Soza Softball Slam | PC | | Original | | PCD-5048-001 | |
| Sammy's Science House | PC | 1.0 | Original | | | |
| Sammy's Science House | PC | 1.1 | Original | | | |
| Sammy's Science House | PC | 3.0 | Southwestern Kids' Collection | | R2522/8612a.7.01 | |
| Sampler Disc for PSP Vol. 1 | PSP | 1.00 | Demo | | UCJB-98301 | |
| Samurai Champloo: Sidetracked | PS2 | 1.00 | Original | | SLUS 21343 | |
| Samurai Jack: The Shadow of Aku | GC | | Original | | DL-DOL-GJCE-USA | |
| Samurai Jack: The Shadow of Aku | PS2 | 1.03 | Original | | SLUS-20899 | |
| Samurai Shodown | MCD | | Original | | T-60175 | |
| Samurai Shodown Anthology | WII | | Original | | RVL-RSSE-USA | |
| Samurai Shodown Anthology | PSP | 1.02 | Original | | ULUS 10401 … | |
| Samurai Shodown Anthology | PS2 | 1.01 | Original | | SLUS 21629 | |
| Samurai Shodown II | PC | | Dual Jewel | | CD-C95-1302-0 | |
| Samurai Shodown II | PC | | Original | | CD-C95-1166-0 | |
| Samurai Shodown III: Blades of Blood | PSX | | Original | | SCUS-94206 | |
| Samurai Shodown Sen | XBOX360 | | Original | | SN-2005 | |
| Samurai Shodown V | XBOX | | Original | | SN-004 | |
| Samurai Shodown: Warriors Rage | PSX | | Original | | SLUS-01039 | |
| Samurai Warriors | XBOX | | Original | | KO-006 | |
| Samurai Warriors | PS2 | 1.00 | Original | | SLUS 20878 | |
| Samurai Warriors 2 | PS2 | 1.01 | Original | | SLUS-21462 | |
| Samurai Warriors 2: Empires | XBOX360 | | Original | | KO-2006 | |
| Samurai Warriors 2: Empires | PS2 | 1.00 | Original | | SLUS 21585 | |
| Samurai Warriors 2: Xtreme Legends | PS2 | 1.02 | Original | | SLUS 21726 | |
| Samurai Warriors 3 | WII | | Original | | RVL-S59E-USA-E0 | |
| Samurai Warriors: Katana | WII | | Beta | | | |
| Samurai Warriors: Katana | WII | | Original | | RVL-RS5E-USA | |
| Samurai Warriors: State of War | PSP | 1.01 | Original | | ULUS-10089 | |
| Samurai Warriors: Xtreme Legends | PS2 | 1.00 | Original | | SLUS-21080 | |
| Samurai Western | PS2 | 1.00 | Trade Demo | | SLUS-28051 | |
| Samurai Western | PS2 | 1.01 | Original | | SLUS 21187 | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | 170121 | |
| The San Diego Zoo Presents... The Animals! | MCD | | Original | | T-87015 | |
| The San Diego Zoo Presents... The Animals! | 3DO | | Original | | | |
| San Francisco Rush 2049 | DC | 1.000 | Demo | | T-9707ND | |
| San Francisco Rush 2049 | DC | 1.001 | Original | | T-9707N | |
| San Francisco Rush The Rock: Alcatraz Edition | PC | | Bundle Version Quantum3D OEM | | 740-0033-01 #QM049 | |
| San Francisco Rush: Extreme Racing | PSX | | Original | | SLUS-00505 | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sandwarriors | PC | 1.11 | Original | | CD-ICD-297-0 | |
| Sanitarium | PC | | Demo | | | |
| Sanitarium (Disc 1) | PC | 1.00 RC15 / Build 836 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | 1.00.000 | Rerelease | | | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Santa Claus Is Comin' to Town! | WII | | Original | | RVL-SX5E-USA-B0 | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Sargon Chess | CDI | | Original, Original: Longbox | | 310690030-2 | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| SAS: Secure Tomorrow | PC | 1.0 | Original | | | |
| Satisfashion: Rock the Runway | WII | | Original | | RVL-SS5E-USA-B0 | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Saturday Night Speedway | PS2 | 1.00 | Original | | SLUS 20640 | |
| Saturn Bomberman | SS | 1.003 | Original | | 81070 | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Savage Skies | PS2 | 1.02 | Original | | SLUS 20430 | |
| Savage Warriors | PC | 1.0 | Original | | 2205110-S90001/1055SA | |
| Savage Warriors | PC | 1.0 | Original | | | |
| Savage: The Battle for Newerth | PC | 1.0 | Original | | | |
| Savage: The Ultimate Quest for Survival | PC | 1.0 | | | | |
| Save Planet Polluto | PC | 1.0 | Original | | | |
| Saw | XBOX360 | | Original | | KN-2050 | |
| Saw | PS3 | 01.00 | Original | | BLUS-30358 | |
| Saw II: Flesh & Blood | XBOX360 | | Original | | KN-2082 | |
| Saw II: Flesh & Blood | PS3 | 01.00 | Original | | BLUS-30548 | |
| SBK 09: Superbike World Championship SBK: Superbike World Championship | PS3 | 01.01 | Original | | BLUS-30519 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK X: Superbike World Championship | PS3 | 01.00 | Original | | BLUS-30683 | |
| SBK: Superbike World Championship | XBOX360 | | Original | | CN-2005 | |
| SBK: Superbike World Championship | PS3 | 01.01 | Original | | BLUS-30236 | |
| SBK: Superbike World Championship | PS2 | 1.01 | Original | | SLUS 21817 | |
| SBK: Superbike World Championship | PSP | 1.01 | Original | | ULUS-10395 | |
| Scaler | GC | | Original | | DL-DOL-GKUE-USA | |
| Scaler | PS2 | 1.00 | Original | | SLUS-20957 | |
| Scarface: Money. Power. Respect. | PSP | 1.01 | Original | | ULUS-10148 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCE-USA | |
| Scarface: The World Is Yours | PS2 | 1.00 | Original, Collector's Edition | | SLUS 21111 … | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 300202 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2038 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCX-CAN-B0 | |
| Scene It? Bright Lights! Big Screen! | PS3 | 01.02 | Original | | BLUS-30448 … | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2037 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCE-USA-B0 | |
| Scene It? Bright Lights! Big Screen! | PS3 | 01.02 | Original | | BLUS-30447 | |
| A Scene It? Lights, Cameraction | XBOX360 | | Original | | MS-2098 | |
| Scene It? Twilight | WII | | Original | | RVL-SCNE-USA-B0 | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey | PC | 0.99 | Playable Demo | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Scholastic's The Magic School Bus Discovers Flight: Activity Center | PC | 1.0.0.2 | Original | | 0201 Part No. X06-16068 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| School Tycoon | PC | | Scholastic | | P/N: CDR 21661-1R | |
| School Tycoon | PC | | Original | | | |
| School Tycoon | PC | v1 | Original | | | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Phonics: Grades 2-3 | PC | v.5 | Original | | 08064 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! Grammar Rock | PC | | SmartSaver | | SGR744AE-CD | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | MAC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | PC | 1.0 | Scholastic | | P/N CDR9835984 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Math Rock | PC | | Smart Saver | | SHR744AE-CD | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| The Sci-Fi Collection | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Science Is Elementary 1 | PSX | | Original | | LSP-990161 … | |
| Science Is Elementary 2 | PSX | | Original | | LSP-990162 … | |
| Science Is Elementary 3 | PSX | | Original | | LSP-990163 … | |
| Science Papa | WII | | Original | | RVL-RZEE-USA-B0 | |
| Scissors 'n' Stones | PC | | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo and the Cyber Chase | PSX | | Demo | | SLUS-90098 | |
| Scooby-Doo and the Cyber Chase | PSX | | Original, Greatest Hits | | SLUS-01396 … | |
| Scooby-Doo! | IXL | 1.0.0 | Original | | R9709 | |
| Scooby-Doo! | IXL | 2.0.0 | Original | | R9709 | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Scooby-Doo! and the Spooky Swamp | WII | | Original | | RVL-SJ2E-USA-B0 | |
| Scooby-Doo! and the Spooky Swamp | PS2 | 1.01 | Original | | SLUS 21928 | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Scooby-Doo! First Frights | WII | | Original | | RVL-RQNE-USA-B0 | |
| Scooby-Doo! First Frights | PS2 | 1.00 | Original | | SLUS-21900 | |
| Scooby-Doo! Jinx at the Sphinx | PC | | Scholastic | | 380849-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3E-USA | |
| Scooby-Doo! Mystery Mayhem | PS2 | 1.00 | Original | | SLUS-20701 | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Night of 100 Frights | XBOX | | Original | | TQ-031 | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Night of 100 Frights | GC | | Original | | DL-DOL-GIHE-USA | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 1.01 | Original, Greatest Hits | | SLUS 20349 … | |
| Scooby-Doo! Night of 100 Frights | GC | Rev 1 | Original | | DL-DOL-GIHE-USA | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooby-Doo! Unmasked | GC | | Original | | DL-DOL-G5DE-USA | |
| Scooby-Doo! Unmasked | PS2 | 1.01 | Original | | SLUS-21091 | |
| Scooby-Doo! Who's Watching Who? | PSP | 1.01 | Original | | ULUS-10168 | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scorched Planet | PC | | Original | | | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scorcher | SS | 1.008 | Original | | 81214 | |
| Scorcher | SS | 2.000 | Original | | 81214 | |
| Score 4 | PC | | Original | | | |
| Score International Baja 1000: The Official Game | PC | | Original | | 35619./101.US | |
| Score International Baja 1000: The Official Game | WII | | Original | | RVL-RJCE-USA | |
| Score International Baja 1000: The Official Game | PS3 | 01.00 | Original | | BLUS-30230 | |
| Score International Baja 1000: The Official Game | PS2 | 1.00 | Original | | SLUS 21850 | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.00 | Demo | | SLUS 29036 | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.03 | Original | | SLUS-20424 | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| Scrabble | PC | | General Mills | | | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PSX | | Original | | SLUS-00903 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble | PSP | 1.00 | Original | | ULUS-10412 | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| Scrabble: Crossword Game | MAC | 1.0.0.52 | Original | | P/N 10328-5 | |
| Scramble Cobra | 3DO | | Original | | FZ-SM0404 | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Scratches | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Screamer | PC | | White Label | | | |
| Screamer | PC | | White Label | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| The Scroll | PC | | | | | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| SD Gundam Force: Showdown! | PS2 | 1.01 | Original | | SLUS 20698 | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLUS-21741 | |
| Sea-Doo Hydro Cross | PSX | | Original | | SLUS-01149 | |
| SeaBlade | XBOX | | Original | | VU-023 | |
| Seal of Evil | PC | | Original | | 904066DVD | |
| Seal of the Pharaoh | 3DO | | Original | | FZ-SM1751 | |
| Seaman | DC | 1.001 | Original | | 51048 | |
| Search & Rescue 3 | PC | 1.0.0.0 | Original | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZE-USA | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLUS 21289 | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Second Sight | PS2 | 1.00 | Original | | SLUS-21033 | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Agent Clank | PSP | .01 | Beta | | UCUS-98697 | |
| Secret Agent Clank | PSP | 1.00 | Demo | | UCUS 98707 | |
| Secret Agent Clank | PS2 | 1.00 | Original | | SCUS 97623 | |
| Secret Agent Clank | PSP | 1.01 | Original, Greatest Hits, Secret Agent Clank + Daxter UMD Dual Pack | | UCUS 98697 … | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| The Secret of Googol 1: Reshaping Googol: Submarine / Tower | PC | 2.0 | Original | | | |
| The Secret of Googol 1a: Reshaping Googol: The Submarine | PSX | | Original | | LSP-020160 … | |
| The Secret of Googol 1b: Reshaping Googol: The Tower | PSX | | Original | | LSP-020150 … | |
| The Secret of Googol 2: Reshaping Googol: Castle / Ocean | PC | 2.0 | Original | | | |
| The Secret of Googol 2a: Reshaping Googol: The Castle | PSX | | Original | | LSP-020180 … | |
| The Secret of Googol 2b: Reshaping Googol: Under the Ocean | PSX | | Original | | LSP-020170 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PSX | | Original | | LSP-020260 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PSX | | Original | | LSP-020280 … | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PC | 2.0 | Original | | | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PSX | | Original | | LSP-020450 … | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PSX | | Original | | LSP-020570 … | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PSX | | Original | | LSP-020650 … | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PSX | | Original | | LSP-020780 … | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island | PC | 2.3 | Original, Bundle Version OEM | | 2147010-590001 / I 042 | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| The Secret Saturdays: Beasts of the 5th Sun | PSP | 1.00 | Original | | ULUS-10443 | |
| The Secret Saturdays: Beasts of the 5th Sun | PS2 | 1.01 | Original | | SLUS-21896 | |
| Secret Service | PS2 | 1.01 | Original | | SLUS 21836 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.00 | Review Build | | SLUS-20762 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLUS 20762 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy Seek & Destroy | PC | | Original | | EPSAD01 | |
| Seek and Destroy Seek & Destroy | PC | 1.0 | Original | | J230D | |
| Seek and Destroy | PS2 | 1.01 | Original | | SLUS 20606 | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Bass Fishing | WII | | Original | | RVL-RBTE-USA | |
| Sega Bass Fishing | DC | 1.000 | Original, Sega All Stars | | 51006 | |
| Sega Bass Fishing 2 | DC | 1.080 | Original | | 51166 | |
| Sega Bass Fishing Duel Bass Fishing Duel: Sega Sports | PS2 | 1.02 | Original | | SLUS 20339 | |
| Sega Classics Arcade Collection | MCD | 1.00 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Collection | PS2 | 1.01 | Original | | SLUS 21009 | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega E3 2002 Art Disc | PC | | Press Kit | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega Genesis Collection | PS2 | 1.01 | Original | | SLUS 21542 | |
| Sega Genesis Collection | PSP | 1.01 | Original, SEGA Fun Pack | | ULUS-10192 | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega GT 2002 | XBOX | | Original | | SE-003 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega Marine Fishing | DC | 1.001 | Original | | 51096 | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally 2 Sega Rally 2: Sega Rally Championship | DC | 1.003 | Original | | 51019 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Rally Championship | SS | 1.006 | Original, Sega Saturn NetLink Bundle | | 80012, 81207 | |
| Sega Rally Championship Plus Netlink Edition | SS | 1.001 | Net Link Game Pack | | 81215, 81608 | |
| Sega Rally Revo | PS3 | 01.00 | Original | | BLUS-30068 | |
| Sega Rally Revo | PSP | 1.00 | Original | | ULUS-10311 | |
| Sega Saturn Bootleg II: On the Road Sega Screams Volume 1 | SS | 1.002 | Not for Resale | | 81068, 81075 | |
| Sega Saturn Choice Cuts | SS | 1.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Saturn Choice Cuts | SS | 2.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Screams Volume 2 | SS | 2.000 | Not for Resale | | 81077 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Sega Smash Pack 2 | PC | | Original, Sonic Action 4 Pack | | 30107.101.US | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Smash Pack: Volume 1 | DC | 1.002 | Original, Bundled with DC | | 51146 | |
| Sega Soccer Slam | XBOX | | Original | | SE-020 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSE-USA | |
| Sega Soccer Slam | PS2 | 1.00 | Original | | SLUS-20509 | |
| Sega Sports Tennis | PS2 | 1.01 | Original | | SLUS 20480 | |
| Sega Superstars | PS2 | 1.00 | Original | | SLUS 20999 | |
| Sega Superstars Tennis | WII | | Original | | RVL-RT5E-USA | |
| Sega Superstars Tennis | PS3 | 01.01 | Original | | BLUS-30123 | |
| Sega Superstars Tennis | PS2 | 1.01 | Original | | SLUS 21733 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Touring Car Championship | SS | 1.001 | Original, Sample | | 81216 | |