Region | Title | System | Version | Edition | Languages | Serial | Status |
| Shadow of the Colossus | PS2 | 1.00 | Original, Greatest Hits | | SCUS 97472 | |
| Squaresoft on PlayStation 1998 Collector's CD Vol. 1 | PSX | | | | SLUS-90028 | |
| Sonic Mega Collection | GC | | Original, Player's Choice | | DL-DOL-GSOE-USA | |
| Squaresoft on PlayStation 2000 Collector's CD Vol. 3 | PSX | | | | SLUS-90075 | |
| Sega Genesis Collection | PS2 | 1.01 | Original | | SLUS 21542 | |
| Street Fighter Collection (Disc 1) | PSX | | Original | | SLUS-00423 | |
| Street Fighter Collection (Disc 2) | PSX | | Original | | SLUS-00584 | |
| Shadow of the Colossus | PS2 | 1.00 | Demo | | SCUS 97505 | |
| Street Fighter Anniversary Collection | PS2 | 1.02 | Original | | SLUS 20949 | |
| Sonic Gems Collection | GC | | Original, Player's Choice | | DL-DOL-G2XE-USA | |
| Squaresoft on PlayStation 1998 Collector's CD Vol. 2 (Final Fantasy VIII Demo) | PSX | | Demo | | SLUS-90029 | |
| Sonic & Knuckles Collection | PC | 1.0 | Expert Software, Sonic Action 4 Pack | | 6820 01, T-6820-02 | |
| Syberia Collectors Edition: I & II | PC | | Original | | 16660-DVD | |
| Spec Ops: Platinum Collection (Disc 2) | PC | 1.0 | Original | | | |
| Sega Classics Collection | PS2 | 1.01 | Original | | SLUS 21009 | |
| Street Fighter Collection 2 | PSX | | Fighters Edge | | SLUS-00746 | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| Space Quest: Collection Series (Disc 1) | PC | | Original | | | |
| Space Quest: Collection Series (Disc 2) | PC | | Original | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Squaresoft on PlayStation Collector's CD | PSX | | | | SCUS-94256 | |
| Sonic Colors | WII | | Original | | RVL-SNCE-USA-B0 | |
| Street Fighter Collection (Disc 1) | SS | 1.000 | Original | | T-1222H | |
| Street Fighter Collection (Disc 2) | SS | 1.000 | Original | | T-1222H | |
| Sonic Mega Collection Plus | PS2 | 1.00 | Original, Greatest Hits | | SLUS 20917 … | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0A | Collector Series, Rerelease | | 2064130, 8051832 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Rerelease | | 2054130 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Original | | 635930 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Sega Classics Arcade Collection | MCD | 1.00 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | Original | | 2061830 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051831 | |
| The Sly Collection | PS3 | 01.00 | Original | | BCUS-98246 | |
| SimCity 2000: CD Collection | PC | 1.00 | Windows 95 | | 0026-000-0601-A | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | The LucasArts Archives Vol. II: Star Wars Collection | | 8031832 | |
| Sega Genesis Collection | PSP | 1.01 | Original, SEGA Fun Pack | | ULUS-10192 | |
| Street Fighter Collection (Disc 1) | PSX | Rev 1 | Fighters Edge | | SLUS-00423 | |
| Street Fighter Collection (Disc 2) | PSX | Rev 1 | Fighters Edge | | SLUS-00584 | |
| Silent Hill: HD Collection | PS3 | 01.00 | Original | | BLUS-30810 | |
| Sonic's Ultimate Genesis Collection | XBOX360 | | Platinum Hits | | SE-2064 | |
| Sonic & Knuckles Collection | PC | | Original, Jack in the Box | | 85037 | |
| Star Wars: Knights of the Old Republic Collection | PC | 1.0.3.0 | Original | | | |
| SimCity 2000: CD Collection | MAC | 1.0 | Original | | 0026-000-0601-A | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0.0.1 | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061831 | |
| Star Wars: X-Wing: Collector's CD-ROM / Star Wars: X-Wing vs. TIE Fighter: Flight School | PC | | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061830 | |
| Street Fighter Anniversary Collection | XBOX | | Original | | CC-015 | |
| Sid Meier's Civilization IV: Colonization | PC | | Original | | 31491-1 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | MAC | 1.0 | Original | | 2062130 | |
| Star Wars: X-Wing: Collector's CD-ROM | MAC | 1.01 | Original | | 2052130 | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| Strategy Challenges Collection 1 | PC | 1.04 | Original, OEM Bundle | | 102771 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| Sail with Columbus | VIS | | Original | | 25-6181 | |
| Super Collapse! 3 | PSP | 1.01 | Original | | ULUS-10287 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| Super Collapse! 3 | PC | | Original | | | |
| SimAnt SimAnt: The Electronic Ant Colony | PC | | CD-ROM Classics, 10 Sims for $20 | | 1111407 | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| Syberia Collection | PS3 | 01.00 | Original | | BLUS-31429 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Sonic Mega Collection Plus | PS2 | 0.80 | Beta | | | |
| Super Collapse! II | PC | 1.33 | Original | | | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051832 | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| The Sci-Fi Collection | PC | | Original | | | |
| The Stronghold Collection | PC | | Original | | 31684-1 | |
| Systemax Ultimate Software Collection (Disc 01) (Daria's Inferno / Who Wants to Beat Up a Millionaire) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 02) (I See Sue... the T. Rex / Amazons & Aliens / Cheerios: Playtime) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 03) (How Many Bugs in a Box? / More Bugs in Boxes / Jim Henson's Muppet Babies: Toyland Train / Miss Spider's Tea Party) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 04) (Forbes: Corporate Warrior / Starwebs: Web Shop / Writing Tutor / Complete Idiots Guide: Marketing Materials Maker) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 05) (S&S Encyclopedia / Typing Tutor 12) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 06) (Women's Fitness / Christina Aguilera: Follow Your Dreams) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 08) (Garfield: Mad About Cats / Money Town) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 09) (Darkened Skye: Disc 1 / Zoboomafoo with the Kratt Brothers Animal Kids) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 10) (Deer Avenger / Ski-Doo X-Team Racing) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 11) (Pearl Harbor: Zero Hour / Real War) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 12) (S&S Encyclopedia of Science / Curious George: Reads, Writes and Spells) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 13) (Multimedia Billiards / Astrology Starscopes / Music Match Juke Box Deluxe 6.1 / Extreme Chess / Typing Tutor Jr. / Bumper Wars) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 14) (Darkened Skye: Disc 2) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 18) (M&M's: The Lost Formulas) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 21) (Mob Rule) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 22) (Richard Scarry's: Busy Town) | PC | 2.0 | Original | | | |
| Systemax Ultimate Software Collection (Disc 26) (Sabrina, the Teenage Witch: Brat Attack) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 27) (Star Trek: Deep Space Nine - The Fallen) | PC | | Original | | | |
| The Sims: Complete Collection | MAC | 2.9.1 | Original | | 11370-1DDA | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| The Sims 2: Best of Business Collection | PC | 2.0 | Original | | 1685507 | |
| The Sims 2: Fun with Pets Collection | PC | 2.1 | Original | | 1685607 | |
| The Sims 2: University Life Collection | PC | 2.0 | Original | | 1685207 | |
| SSI Strategy Collection: Critic's Choice Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| Space Colony | PC | | Original | | | |
| Super GameHouse Collection Super Collapse! / Super Glinx! / Super Nisqually | PC | | MacPlay | | | |
| Space Colony | PC | | Interactive Demo | | | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sword of the Stars: Ultimate Collection | PC | 1.6.7 | Original | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| Super GameHouse Solitaire Collection | PC | | Original | | | |
| The Sudoku Challenge! Collection | PC | | Original | | | |