Region | Title | System | Version | Edition | Languages | Serial | Status |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| Sacred 2 (Disc 1) | PC | | Original | | | |
| Sacred 2 (Disc 2) | PC | | Original | | | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| The Sacred Amulet | PC | | Original | | | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Saints Row: The Third (Disc 1) | PC | | Original | | | |
| Saints Row: The Third (Disc 2) | PC | | Original | | | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives: Adventure Collection | | | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives Vol. I | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Samantha Swift and the Golden Touch Samantha Swift Bundle | PC | | Original | | | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | | |
| The San Diego Zoo Presents... The Animals! | 3DO | | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scorched Planet | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega E3 2002 Art Disc | PC | | Press Kit | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Self Selling Disc | CDI | 01 | Original | | | |
| Self Selling Disc | CDI | 3.1 | | | | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Serious Sam Gold (Disc 1) | PC | 1.05 | Original | | | |
| Serious Sam Gold (Disc 2) | PC | 1.05 | Original | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Shade: Wrath of Angels (Press Disc) | PC | | Press Kit | | | |
| Shadow Man | PC | | Demo | | | |
| Shadow Man | PC | | Original | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow Watch | PC | 1.0 | Original | | | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| Shadowlands | PC | | Megapak 2 | | | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shanghai Double Pack | PC | | Original | | | |
| SharkPort: Code and Save Transfer Kit | PC | 1.04 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PC | 1.10 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.2 | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.23 | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 2.21 | Unlicensed | | | |
| Shaun White Snowboarding: Road Trip | WII | | Beta | | | |
| Shelley Duvall's It's a Bird's Life | 3DO | | Original | | | |
| Sherlock Holmes: Consulting Detective: Vol. I Sherlock Holmes: Consulting Detective: Vol. 1 | PC | | 5 ft. 10 PAK Vol. 2 | | | |
| Shining Wisdom | SS | 1.000 | Beta | | | |
| Shining Wisdom | SS | 1.000 | Preview | | | |
| Shiren the Wanderer | WII | | Beta | | | |
| Shockwave 2: Beyond the Gate (Disc 01) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 02) | 3DO | | Original | | | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Beta | | | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Sid Meier's Alpha Centauri | PC | 1.0I | CD-ROM Classics | | | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Sid Meier's C.P.U. Bach | 3DO | | Original | | | |
| Sid Meier's Civilization II | PC | 2.42a | Infogrames Rerelease | | | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition (Rerelease) | | | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Pirates! (Disc 1) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 2) | PC | | Rerelease | | | |
| Silent Hill: Downpour | PS3 | 01.01 | Review | | | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.01 | Rerelease | | | |
| Silverload | PC | | | | | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SiN Gold | MAC | | Shooter Pack, MacPlay | | | |
| SiN Gold | MAC | | MacPlay | | | |
| SiN Gold | MAC | 1.1.1 | Original | | | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sing-Along Kids: Vol. 2 | PC | | | | | |
| Sinistar: Unleashed | PC | | Original | | | |
| Sitting Ducks | PC | 1.0 | Rerelease | | | |
| Sitting Ducks | PC | 1.0 | | | | |
| Ski-Doo Snowmobile Challenge | WII | | Beta | | | |
| Skylanders: Spyro's Adventure | PC | | Press Kit | | | |
| SkyMaze X3D SkyMaze | PC | | X3D | | | |
| SkyTrip America SkyTrip America: An Incredible Ride Through U.S. History! | PC | 1.0 | | | | |
| Sleeping Dogs | PS3 | 00.00 | Preview | | | |
| Slingo Deluxe | PC | | Original | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Slingo: Wild 7's | PC | | Oregon Lottery | | | |
| Slots Adventure: War for Olympus | PC | 1.0 | Original | | | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Small Soldiers | PSX | | Preview | | | |
| Smart Steps: Kindergarten | PC | 1.0 | Original | | | |
| Smilingüido em: Desafio na Floresta | PC | | Original | | | |
| Snap Dragon | PC | 1.0 | Original | | | |
| Snap! 3D Bowling | PC | | Original | | | |
| Snoopy vs. the Red Baron | PC | | Original | | | |
| So Who's Dr. Rabbit? | PC | | Original | | | |
| So You Wanna Be a Redneck | PC | | Original | | | |
| Soccer Kid | 3DO | | Original, 3DO Action Pak, Demo Disc (3DO Demo Disc Program) | | | |
| The Software Toolworks CD Game Pack | PC | | Original | | | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| Soldier of Fortune | PC | 1.04 | Linux | | | |
| Soldiers at War | PC | | Preview | | | |
| Sonic and the Secret Rings Comic Book DVD from Archie Comics | PC | | | | | |
| Sonic CD | PC | 1.0 | Sonic Action 4 Pack | | | |
| Sonic CD | MCD | 1.15 | Beta | | | |
| Sonic Riders (Disc 1) | PC | 1.0 | Original | | | |
| Sorority House: An Interactive Game of Hide and Peek | PC | 1.0 | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (PC and Compatibles) Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| Space Invaders | PSX | | Review | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Spacebound Space Bound | PC | | Original | | | |
| Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |
| Spear of Destiny | PC | | Ultimate Game Collection | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Spear of Destiny: Super CD Pack | PC | | Super CD Pack | | | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Freaks (Misc Artwork: PC-CD 2nd July '99) | PC | | Press Kit | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| Spell It Deluxe | PC | | Original | | | |
| Spider-Man | PC | | Demo | | | |
| Spider-Man: Web of Shadows (Final Press Kit) | PC | | Press Kit | | | |
| Spintires Spintires: Offroad Truck Simulator | PC | | Original | | | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Basketball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Soccer | PC | | Wendy's Kids' Meal | | | |
| Sportsman's Double Play | PC | 1.0.0 | Original | | | |
| Spring 2012 Refresh Standard: PS3 IDU 4.11 | PS3 | | Kiosk Demo | | | |
| Spring 2013: Standard IDU 4.31 | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2010: 3.21 IDU Update (E-M) | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2011 3.60 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Spy Fox in "Dry Cereal" | PC | | Demo | | | |
| Spyro the Dragon | PSX | | SCEE Preview | | | |
| Spyro the Dragon | PSX | | SCEA Preview | | | |
| Squad Assault: Second Wave | PC | 1.80 | Original | | | |
| Square Enix E3 2004 Media CD | PC | | Press Kit | | | |
| Square Enix E3 2005 Media CD | PC | | Press Kit | | | |
| Square Enix: Final Fantasy VII Advent Children Trailer | PC | | Press Kit | | | |
| SquareSoft: E3 2001 Media CD | PC | | Press Kit | | | |
| SSI Strategy Collection: Critic's Choice Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| Star Crusader | PC | | Original | | | |
| Star Fox Adventures: Game Preview CD | PC | | Promo | | | |
| Star Trek Omnipedia | PC | | Original | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Rerelease | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | | |
| Star Trek: Armada | PC | 1.0 | Original | | | |
| Star Trek: Deep Space Nine: Dominion Wars | PC | 1.00 | Original | | | |
| Star Trek: Deep Space Nine: The Fallen (Demo and Trailer) | PC | 11-2000-a | Demo | | | |
| Star Trek: Judgment Rites | PC | | Limited CD-ROM Collector's Edition | | | |
| Star Trek: Klingon (Disc 1) (Installation) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon (Disc 2) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon Academy | PC | 1.0 | Demo | | | |
| Star Trek: New Worlds | PC | 1.0 | Original | | | |
| Star Trek: Starfleet Academy: Chekov's Lost Missions | PC | | Original | | | |
| Star Trek: The Next Generation: Birth of the Federation | PC | | Original | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Trilogy CD-ROM: Limited Edition Entertainment Utility | PC | | Original | | | |
| Star Wars: Behind the Magic: Vehicles Special Edition | PC | 1.0 | Original | | | |
| Star Wars: DroidWorks | PC | 1.0 | Original | | | |
| Star Wars: Episode I: Cover Disk 4 | PC | | Press Kit | | | |
| Star Wars: Episode I: Disc #3: Covers | PC | | Press Kit | | | |
| Star Wars: Episode I: Racer | PC | 1.0 | Limited Run Games | | | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | LucasArts Archive Series | | | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | LucasArts Archive Series | | | |
| Star Wars: Knights of the Old Republic Collection | PC | 1.0.3.0 | Original | | | |
| Star Wars: Millennium Falcon CD-ROM Playset | PC | | Original | | | |
| Starbright Asthma CD-ROM Game: Quest for the Code | PC | | | | | |
| StarCraft II: Legacy of the Void (Disc 1) | PC | | Original | | | |
| StarCraft II: Legacy of the Void (Disc 2) | PC | | Original | | | |
| StarCraft: Brood War (Expansion Set) | PC | 1.15.2 | StarCraft Battle Chest | | | |
| Stardew Valley | PC | 1.4.5 | Fangamer | | | |
| Starfighter Assets CD | PC | | Press Kit | | | |
| Starship Titanic (Disc 1) Douglas Adams: Starship Titanic | PC | 1.00.42b | Rerelease | | | |
| State of Decay: Year-One Survival Edition | PC | | Original | | | |
| Stay Tooned! | PC | 1.0 | Original | | | |
| Steel Soldiers | PC | | Original | | | |
| Steel Tide | PC | 1.0.0.1 | Original | | | |
| Stellar 7: Draxon's Revenge | 3DO | | Original | | | |
| Stellar Forces Stellar Forces Expansion Pak: Over 50 Add-On Levels for StarCraft | PC | 2.0 | Original | | | |
| A Steven Spielberg Film: Minority Report: Bonus CD-ROM! | PC | | Original | | | |
| Stories: The Path of Destinies (Installation Disc) | PC | 0.0.18092 | Collector's Edition, GameTrust Collection | | | |
| Storybook Weaver Deluxe | PC | 1.0 | Original | | | |
| Stowaway DK Multimedia: Stephen Biesty's Incredible Cross-Section: Stowaway | PC | | | | | |
| Strange Adventures in Infinite Space | PC | | Cheapass Games | | | |
| Strategic Command: European Theater | PC | 1.0 | Original | | | |
| Stray Souls: Dollhouse Story | PC | | Original | | | |
| Streak Hoverboard Racing | PSX | | Beta | | | |
| Street Fighter Alpha: Warriors' Dreams | PC | | Original | | | |
| Street Fighter Alpha: Warriors' Dreams | SS | 1.000 | Beta | | | |
| Street Fighter IV: The Ties That Bind (Bonus Disc) | XBOX360 | | Xbox 360 Game Bundle | | | |
| Strike Commander | PC | | CD-ROM Classics | | | |
| Strike Commander | PC | | EA Gold CD-ROM Classics | | | |
| Strong Bad's Cool Game for Attractive People | PC | 1.5.0.0 | Original | | | |
| Stronghold | PC | 1.1 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | | Stronghold Warchest | | | |
| Stronghold (Bonus Castle: The Tower of London) | PC | | Pre-Order Bonus | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.0 | Original | | | |
| Stronghold | PC | 1.00 | Slash Corporation | | | |
| Stronghold | PC | 1.00 | Dungeons & Dragons Ultimate Fantasy | | | |
| Stronghold | PC | 1.00 | Dungeons & Dragons Ultimate Fantasy | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.1 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.2 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.3 | Demo | | | |
| Stronghold 2 (Disc 1) (Install) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| Stronghold 2 (Disc 2) (Play) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| Stronghold Crusader FireFly Studios' Stronghold Crusader | PC | 1.0 | Original | | | |
| Stupid Invaders (Disc 1) | PC | 1.0 | Original | | | |
| Stupid Invaders (Disc 2) | PC | 1.0 | Original | | | |
| Stupid Invaders (Disc 3) | PC | 1.0 | Original | | | |
| Stupid Invaders (Disc 4) | PC | 1.0 | Original | | | |
| Sudoku Ball: Detective | PC | 1.1 | Original | | | |
| The Suffering: Ties That Bind (Disc 1) | PC | | Original | | | |
| The Suffering: Ties That Bind (Disc 2) | PC | | Original | | | |
| The Suffering: Ties That Bind (Disc 3) | PC | | Original | | | |
| Summer Refresh 2011: 3.65 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Sundance Channel: Sept. 2000 | PHOTO-CD | | | | | |
| Super 3D Noah's Ark | PC | | Original | | | |
| Super Arcade Games: Version 5 | PC | | Original | | | |
| Super Bender Boot Disc | PS2 | 2.00 | | | | |
| Super Games for Windows: Volume II | PC | | Original | | | |
| Super Mario's Wacky Worlds | CDI | 0.11 | Prototype | | | |
| Super Meat Boy: Ultra Edition | PC | | Original | | | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.01 | Rerelease | | | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Rerelease | | | |
| Super Solvers: Midnight Rescue! | PC | 1.0 | Original | | | |
| Super Solvers: Spellbound! | PC | 1.1 | Rerelease | | | |
| Super Street Fighter II Turbo HD Remix (Asset Disc) | PC | | Super Turbo Hyper Champion Special Edition Pack | | | |
| Super Wing Commander | 3DO | | Original, Demo Disc (3DO Demo Disc Program) | | | |
| SuperCharged Xpansion Pack SuperCharged Xpansion Pack for Doom, Doom II & Hexen | PC | | Rerelease | | | |
| Superdead | PC | | Original | | | |
| SuperModels Go Wild | 3DO | | Original | | | |
| Supreme Commander (Bonus Disc) | PC | | Original | | | |
| Supreme Commander 2 | PC | | Original | | | |
| SWAT 4: The Stetchkov Syndicate | PC | | Original | | | |
| Sword of the New World: Granado Espada | PC | 2.1.18 | | | | |
| Sword of the Stars: Ultimate Collection | PC | 1.6.7 | Original | | | |
| Symbol Set 1: Fantasy Overland | PC | | Original | | | |
| Syndicate | 3DO | | Original | | | |
| Syndicate Plus | PC | | | | | |
| Syndicate Plus | PC | | Bundle Version OEM | | | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Star Wars: Episode I: The Gungan Frontier | PC | 1.0 | Original | | #3512030 | |
| Star Wars: Anakin's Speedway | PC | | Original | | #3518030 | |
| Star Wars: Jar Jar's Journey Adventure Book | PC | 1.0 | Original | | #3520530 | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Star Miner: Battle for Supremacy Asteroid Miner | PC | 1.30 FULL | Pocketware | | #9 | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | #SBW744BE-CD | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Sid Meier's Civilization II | PC | 1.0 | Original | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42 | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization II: Fantastic Worlds | PC | | Original | | 0-529-47-101 | |
| Star Trek: The Next Generation: Klingon Honor Guard (Install Disc) | PC | 1.0 | Original | | 0-539-47-101 | |
| Star Trek: The Next Generation: Klingon Honor Guard (Game Disc) | PC | 1.0 | Original | | 0-539-47-102 | |
| Star Trek: Starship Creator Deluxe | PC | | Original | | 0-671-31776-8 | |
| Star Trek: Deep Space Nine: The Fallen | PC | 1.0 | Original | | 0-671-57663-1 | |
| Shadowgrounds (Disc 1) | PC | 1.01 | Original | | 000046-CD1 | |
| Shadowgrounds (Disc 2) | PC | 1.01 | Original | | 000046-CD2 | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| SimCity 2000: CD Collection | MAC | 1.0 | Original | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.00 | Windows 95 | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| SimTown: The Town You Build Yourself! | MAC | | Original | | 0037-000-0601-A, 0037-029-0601-A | |
| Star Crusader | PC | 1.0n | Bundle Version OEM | | 0061-0085-00 | |
| Star Crusader | PC | 1.1 | Bundle Version OEM | | 0061-0085-01 | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Megapak 8 | | 01130-059-0601 | |
| SimCity 2000 Special Edition | PC | | Original | | 0126-000-0601-A | |
| SimCity 2000 Special Edition | MAC | 1.0 | Original | | 0126-000-0601-A | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Original | | 0130-000-0601-A | |
| Sudoku Master | PC | 1.0 | Original | | 02-0950-10 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus Discovers Flight: Activity Center | PC | 1.0.0.2 | Original | | 0201 Part No. X06-16068 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Sudoku Master | PC | | Rerelease | | 03659 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Spy Kids Learning Adventures: The Candy Conspiracy | PC | | Original | | 03962 | |
| Spy Kids Learning Adventures: The Nightmare Machine | PC | | Original | | 03963 | |
| SuperKarts | PC | | Original | | 04-10242CD | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Star Command Revolution | PC | 1.0 | Original | | 04-12257CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.1 | Shareware | | 04-12264CD | |
| The Smelly Mystery | PC | 1.0 | Original | | 04-12328CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Special Edition | | 04-12884CD | |
| Snowmobile Racing | PC | | Original | | 04-17527CD | |
| Submarine Titans | PC | 1.0 | Original | | 04-21473CDA | |
| Sudden Strike | PC | 1.0.0.1 | Original | | 04-22099CD1 | |
| Sudden Strike (Additional Missions) | PC | 1.0.0.1 | Original | | 04-22099CD2 | |
| Survivor: The Interactive Game | PC | 1.0.0.17 | Original | | 04-22709CDSL | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| Spy Fox in "Dry Cereal" | PC | 1.0 | Original | | 04-70281, Part # 0001407, Part No. 04-00000H1529 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Original | | 0762.05.0 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Original | | 0762.05.0 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| School Zone Phonics: Grades 2-3 | PC | v.5 | Original | | 08064 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Shrek the Third: The Search for Arthur | VFLASH | | Original | | 093140(US) | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Star Trek: Hidden Evil | PC | | Original | | 1000889.101.US | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Soldier of Fortune | PC | 1.03 | Original | | 1000910.101.US | |
| Star Trek: Armada | PC | 1.0 | Original | | 1000913.101.US | |
| Star Trek: Armada | PC | 1.1 | Original | | 1000913.101.US | |
| Star Trek: Armada | PC | 1.2 | Rerelease, Star Trek: Action Pack | | 1000913.101.US, 32257.102.US | |
| Space Invaders | PC | 1.0 | Original | | 1000916.101.US | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Soldier of Fortune | PC | 1.03 | Special Tactical Edition | | 1001348.101.US | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | 10049 | |
| Strike Commander / Wing Commander: Privateer | PC | | Special CD-ROM Edition | | 1009121 | |
| Sacred Gold (Disc 1) | PC | 2.24 | Original | | 10130-CD1 | |
| Sacred Gold (Disc 2) | PC | 1.0 | Original | | 10130-CD2 | |
| Sacred Gold (Disc 3) | PC | 1.0 | Original | | 10130-CD3 | |
| The Sims: Hot Date (Expansion Pack) | MAC | | Original | | 10150-1CDA | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | 1015007 | |
| Sacred (Disc 1) | PC | 1.8 | Rerelease | | 10153-CD1 | |
| Sacred (Disc 2) | PC | 1.8 | Rerelease | | 10153-CD2 | |
| Super Solvers: Spellbound! | PC | 1.0 | Encore | | 10175-CD2 | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Star Wars: Jedi Knight II: Jedi Outcast | MAC | 1.03 | Original | | 10200-1CDA | |
| SimCity 4 (Disc 1) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 2) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 2000 Special Edition | PC | 1.0.0.1 | CD-ROM Classics, Scholastic | | 10365, 1131107, 5710243CSP1 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | MAC | | Original | | 10430-1CDA | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | MAC | | Original | | 10430-2CDA | |
| Star Trek: Elite Force II (Disc 1) | MAC | | Original | | 10440-1CDA | |
| Star Trek: Elite Force II (Disc 2) | MAC | | Original | | 10440-2CDA | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | 105907 | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | MAC | 1.0.1 | Original | | 10610-1CDA | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 2) | MAC | 1.0.1 | Original | | 10610-2CDA | |
| Star Wars: Knights of the Old Republic | MAC | 1.03 | Original | | 10660-1DDA | |
| Shrek 2 | MAC | | Original | | 10700-1CDA | |
| The Sims: Party Pack | MAC | | Original | | 10790-1DDA | |
| SimCity 4 Deluxe Edition | MAC | | Original | | 10830-1DDA | |
| The Sims 2 | MAC | | Rerelease | | 10880-1DDA | |
| The Sims 2 | MAC | 1.0 Rev E (v7535) | Original | | 10880-1DDA | |
| Star Wars: Battlefront | MAC | 1.2 | Original | | 10900-1DDA | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0 | Original | | 109310 | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 1) | PC | 1.0 | Original | | 11001-1CDA | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 2) | PC | 1.0 | Original | | 11001-2CDA | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 3) | PC | 1.0 | Original | | 11001-3CDA | |
| Stubbs the Zombie in Rebel Without a Pulse | MAC | 1.0 (v418) | Original | | 11010-1DDA | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Space Invaders XL | NUON | | Original | | 11109 | |
| The Sims 2: University (Expansion Pack) | MAC | | Original | | 11110-1DDA | |
| SimLife SimLife: The Genetic Playground | PC | | Scholastic Clubs and Fairs | | 1111707, P1 | |
| SpellForce | PC | 1.52.64763 | Platinum Edition | | 11121-1DDA | |
| Supreme Commander: Forged Alliance | PC | 1.5.0.1 | Original, Gold Edition | | 111603 | |
| Sid Meier's Civilization III Complete | MAC | 1.22 | Original | | 11180-1DDA | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Sid Meier's Civilization IV | MAC | 1.61 | Original | | 11250-1DDA | |
| Scrabble Complete | PC | | Original, Monopoly & Scrabble Complete, Scrabble Complete/Jeopardy 2003 | | 11290-CD, Part # 23970CD | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| The Sims 2: Nightlife (Expansion Pack) | MAC | | Original | | 11330-1DDA | |
| The Sims: Complete Collection | MAC | 2.9.1 | Original | | 11370-1DDA | |
| The Sims 2: Open For Business (Expansion Pack) | MAC | | Original | | 11390-1DDA | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| Star Wars: Empire at War | MAC | 1.05 | Original | | 11490-1DDA | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Sims 2: Pets (Expansion Pack) | MAC | | Original | | 11500-1CDA | |
| The Sims 2: Seasons (Expansion Pack) | MAC | | Original | | 11610-1DDA | |
| The Sims 2: Bon Voyage (Expansion Pack) | MAC | | Original | | 11780-1DDA | |
| Sid Meier's Gettysburg! | PC | | CD-ROM Classics | | 1187707 | |
| Sid Meier's Civilization IV: Beyond the Sword | MAC | | Original | | 12090-1DDA | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | MAC | | Original | | 12240-1DDA | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | MAC | | Original | | 12240-1DDA2 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | PC | 0.0.0.0 | Original | | 12241-1DDA | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | PC | 0.0.0.0 | Original | | 12241-1DDA2 | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Star Wars: Jedi Knight Gold Pack | MAC | | Original | | 12280-1DDA | |
| Star Wars: Mac Pack | MAC | | Original | | 12300-1DDA | |
| Sid Meier's Civilization V | MAC | | Original | | 12350-1DDA | |
| Sid Meier's SimGolf | PC | 1.0 | Sim Mania 2 | | 1277387 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 1) | PC | | The Movie Collection | | 1292607, 8531030 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 2) | PC | | The Movie Collection | | 1292617, 8531031 | |
| Silkolene Honda Motocross GP | PC | 1.0 | Original | | 13030 | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| The Sims Strategy Guide and SimFan Pack | PC | | Pre-Order Bonus | | 1414407 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | 1.00 | Original | | 1430717 | |
| Sid Meier's SimGolf | PC | 1.01 | Rerelease | | 1434917 | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.1 | Original, Expansion Collection Volume Two, Mega Deluxe | | 1439827 | |
| SimCity 3000 Unlimited | PC | | Rerelease | | 1446307, 1641507 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | 1457637 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457647 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457657 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Scholastic | | 1459517 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | | Original | | 1474007 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | Original | | 1474007 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| The Sims: Double Deluxe (Bonus CD) | PC | | Double Deluxe, Mega Deluxe | | 1474107 | |
| SimCity 3000 Unlimited | PC | 2.0.949 | Scholastic | | 1500907 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Scholastic | | 1500907 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: Holiday Edition (Disc 2) | PC | 1.0.0.1048 | Original | | 1518917 | |
| The Sims 2: Holiday Edition (Disc 3) | PC | 1.0.0.1048 | Original | | 1518927 | |
| The Sims 2: Holiday Edition (Disc 4) | PC | 1.0.0.1048 | Original | | 1518937 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1022 | 2006 Edition | | 1527607 | |
| The Sims 2: Happy Holiday Stuff | PC | | Original | | 1527707 | |
| Spore: Galactic Adventures | PC | 1.0 | Original | | 1535407 | |
| The Sims 3: World Adventures (Expansion Pack) | PC | 0.2.0.56 | Original, The Sims 3 Expansion Bundle | | 1539307 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | 1578007 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | 1.14.0.72 | Original | | 1578007 | |