Region | Title | System | Version | Edition | Languages | Serial | Status |
| Agatha Christie: Triple Murder Mystery Pack | PC | | | | | |
| Amazing Hidden Object Games 3 Pack: Paranormal Mysteries | PC | | Original | | | |
| Amazing Hidden Object Games 3 Pack: Paranormal Mysteries 2 | PC | | Original | | | |
| Amazing Mahjong Games 4 Pack: Mysterious Lands | PC | | Original | | | |
| Ancient Games of Nations: A.G.O.N.: The Mysterious Codex | PC | | | | | |
| Avner Travels in Time: Judah & the Maccabees Avner Travels in Time: 3"D" Interactive Mystery in Jewish History | PC | | Rerelease | | | |
| Barbie Horse Adventures: Mystery Ride CD-ROM | PC | 1.0c | Original | | S7205410 | |
| Barbie Horse Adventures: Mystery Ride CD-ROM | PC | 1.0c | | | S7205410 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 1) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 1) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 1) | PC | 1.00 | Original | | S238410 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 1) | PC | 1.11 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 2) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 2) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 2) | PC | 1.00 | Original | | S238420 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 2) | PC | 1.11 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 3) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 3) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 3) | PC | 1.00 | Original | | S238430 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 3) | PC | 1.11 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 4) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 4) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 4) | PC | 1.00 | Original | | S238440 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 4) | PC | 1.11 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 5) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 5) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 5) | PC | 1.00 | Original | | S238450 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 5) | PC | 1.11 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 6) | PC | | Gabriel Knight Mysteries: Limited Edition | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 6) | PC | 1.00 | Original | | 832384330/S238140 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 6) | PC | 1.00 | Original | | S238460 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 6) | PC | 1.11 | Original | | 832384330/S238140 | |
| Big Bundle Mystery Pack Big Bundle Mystery Pack: 9 Great Games! | PC | | Original | | P/N: 127548 | |
| A Case for TKKG: The Mystery of the Mayan Treasure | PC | | | | | |
| Castle: Never Judge a Book by Its Cover Castle: Hidden Object Mystery Game | PC | 1.0 | Original | | 33350-CD | |
| Castle: Never Judge a Book by Its Cover Castle: Hidden Object Mystery Game | PC | 1.0 | | | 41890-DVD, 41890-DVD v1.0 | |
| Castle: Never Judge a Book by Its Cover Castle: Hidden Object Mystery Game | PC | 1.0 | Rerelease | | 33350A-DVD | |
| Chronicles of Mystery: The Legend of the Sacred Treasure | PC | | Original | | | |
| Chronicles of Mystery: The Tree of Life | PC | | Original | | | |
| Clue: The Mysteries Continue | CDI | | Original | | 310690644-2 | |
| The ClueFinders: 3rd Grade Adventures: The Mystery of Mathra | PC | 2.4 | Rerelease | | 381579-CD1 | |
| The ClueFinders: Math Adventures Ages 9-12: Mystery in the Himalayas | PC | 2.1 | Original | | 380367-CD1 | |
| The ClueFinders: Math Adventures: Ages 9-12: Mystery of the Stolen Treasures | PC | 2.0 | Deluxe 2 CD-ROM Set | | 378472-CD1 | |
| The ClueFinders: Mystery Adventures! | PC | 1.0 | Demo | | 381308-CD | |
| The ClueFinders: Mystery Mansion Arcade | PC | 1.0 | Deluxe 2CD Set | | ARCADE-CD2 | |
| The ClueFinders: Mystery Mansion Arcade | PC | 1.1 | Deluxe 2CD Set | | ARCADESS-CD2 | |
| The ClueFinders: Reading Adventures Ages 9-12: The Mystery of the Missing Amulet | PC | 1.1 | Original | | 378171AO-CD1 | |
| Detective Barbie: Mystery of the Carnival Caper | PC | | Rerelease | | S2046111 | |
| Detective Barbie: Mystery of the Carnival Caper | PC | 1.0 | Original | | 20461-0919 | |
| Detective Barbie: The Mystery Cruise | PSX | | Original | | SLUS-01221 | |
| Disney Guilty Party: Mystery Fun for Everyone! | WII | | Original | | RVL-SGUE-USA-B0 | |
| Eagle Eye Mysteries in London | MAC | | Original | | 7562 | |
| Farm Mystery: The Happy Orchard Nightmare / Committed: Mystery at Shady Pines: Premium Edition | PC | | Cosmi | | P/N: DVD223D1 | |
| Fear for Sale: Mystery of Melnroy Manor | PC | | Collector's Edition | | 33381010US | |
| Freddi Fish: Kelp Seed Mystery | WII | | Original | | RVL-R2FE-USA | |
| Hidden Mysteries: Buckingham Palace | PC | | Original | | | |
| Hidden Mysteries: Civil War & Buckingham Palace | PC | | Original | | | |
| Hidden Mysteries: Civil War: Secrets of the North & South | PC | | Original | | VA4403 | |
| Hidden Mysteries: Forbidden City: Secrets of the Emperor | PC | 1.0 | Original | | 29111-CD | |
| Hidden Mysteries: Notre Dame: Secrets of Paris | PC | 1.0 | Original | | 29091-CD | |
| Hidden Mysteries: Royal Family / Buckingham Palace: Secrets of Kings and Queens | PC | | Original | | | |
| Hidden Mysteries: Royal Family Secrets | PC | | Big Fish Games Backup CD | | | |
| Hidden Mysteries: Salem Secrets / Lost Secrets: Caribbean Explorer: Secrets of the Sea | PC | | Original | | | |
| Hidden Mysteries: The Fateful Voyage: Titanic / Hollywood: The Director's Cut Hidden Mysteries: Titanic / Lost Secrets: Hollywood Mysteries | PC | | Original | | | |
| Hidden Mysteries: The White House / Lost Secrets: Ancient Mysteries | PC | | Original | | | |
| Hidden Mysteries: Titanic | WII | | Original | | RVL-STTE-USA-B0, RVL-STTE-USA-B1 | |
| Hidden Mysteries: Vampire Secrets / Lost Secrets: A Vampire's Tale: Paris Stories | PC | | Original | | | |
| I Spy Mystery | PC | | Scholastic | | P/N: CDR 9-90060-3 | |
| Inspector Parker Mystery Bundle | PC | 1.0.2.2624 | Original | | 1030-10292 | |
| Jack the Ripper Jack the Ripper: Solve the Mystery! | PC | | | | | |
| Jewel Quest III / Jewel Quest Mysteries: Curse of the Emerald Tear Jewel Quest 2-Pack | PC | | Original | | | |
| Jewel Quest Mysteries 2: Trail of the Midnight Heart | PC | 0.99F.17 | Original | | P/N # 6010606 | |
| Jewel Quest Mysteries: Curse of the Emerald Tear | PC | | Original | | | |
| Jewel Quest Mysteries: The Seventh Gate | PC | | Original | | 126490 | |
| Jewel Quest Mysteries: The Seventh Gate | PC | 1.00.0000 | Original | | 126490 | |
| JumpStart Adventures 3rd Grade: Mystery Mountain | PC | | Original | | ZZJS310CD000CD | |
| JumpStart Adventures 3rd Grade: Mystery Mountain | PC | 1.1 | Rerelease | | | |
| JumpStart Adventures 3rd Grade: Mystery Mountain | PC | 1.1 | Rerelease | | | |
| JumpStart Adventures 3rd Grade: Mystery Mountain | PC | 1.2.0 | Rerelease | | S0378011 | |
| The Lost Secrets: Dracula Mystery Trilogy: The Strange Case Myth of the Vampire, The Destruction of Evil | PC | | Original | | | |
| Lost Secrets: Vatican Mysteries / Hidden Mysteries: Buckingham Palace | PC | | Original | | | |
| Lost Secrets: Vatican Mysteries / Lost Secrets: Bermuda Triangle | PC | | Original | | | |
| Macabre Mysteries: Curse of the Nightingale | PC | | Collector's Edition | | 33400010US | |
| The Making of Riven: The Sequel to Myst | PC | 1.0 | Ages of Myst: Fifth Anniversary Commemorative Edition | | 1842333 | |
| Mary-Kate and Ashley: Magical Mystery Mall | PSX | | Original | | SLUS-01121 | |
| MayaQuest: The Mystery Trail | PC | 1.0 | Original | | #HCD645 | |
| MayaQuest: The Mystery Trail | PC | 1.12 | Rerelease | | PMQ744BE-CD | |
| MayaQuest: The Mystery Trail | PC | 1.12 | SoftKey | | PMQ744DE-CD | |
| Midnight Mysteries 4-Pack | PC | | Original | | 33550-DVD v1.0 | |
| Midnight Mysteries: Devil on the Mississippi | PC | | Collector's Edition | | | |
| Midnight Mysteries: Devil on the Mississippi | PC | | Collector's Edition | | | |
| Midnight Mysteries: Haunted Houdini | PC | 1.0 | Collector's Edition | | 70433-CD | |
| Midnight Mysteries: Salem Witch Trials | PC | | Original | | | |
| Midnight Mysteries: Salem Witch Trials | PC | | Rerelease | | | |
| Midnight Mysteries: The Edgar Allen Poe Conspiracy | PC | | Original | | | |
| Museum Madness Museum Madness: A MECC Science and History Learning Mystery | PC | | SoftKey | | PMU944AE-CD | |
| Myst | AJCD | | Original | | J9069E | |
| Myst | AJCD | | Bundled with Atari Jaguar CD (Demo) | | | |
| Myst | AJCD | | Bundled with Atari Jaguar CD (Demo) | | | |
| Myst | 3DO | | Original | | FZ-SM0204 | |
| Myst | PSX | | Original | | SCUS-94602 | |
| Myst | PC | 1.0 | Original | | | |
| Myst | PC | 1.0.1 | Bundle Version OEM | | | |
| Myst | PC | 1.0.1 | Bundle Version OEM | | OEM No. 18207 | |
| Myst | PC | 1.0.2 | Original | | | |
| Myst | SS | 1.001 | Original | | T-8101H | |
| Myst | MAC | 1.01 | Rerelease | | | |
| Myst | PC | 1.1 | Original | | | |
| Myst | PC | 1.1 | 25th Anniversary Collection | | | |
| Myst | PC | 1.2 | Original | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Ages of Myst: Fifth Anniversary Commemorative Edition | | 1820211B | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3.1 | Original, Ages of Myst, Bundle, Rerelease | | 1820220I | |
| Myst III: Exile | XBOX | | Original | | US-017 | |
| Myst III: Exile | PS2 | 1.01 | Original | | SLUS 20434 | |
| Myst III: Exile | PC | 1.27 | Limited Edition, 10th Anniversary DVD Edition, Myst IV: Revelation Limited Edition | | 651116-DVD3 | |
| Myst III: Exile | PC | 1.27.0 | 25th Anniversary Collection | | | |
| Myst III: Exile (Disc 1) | PC | 1.0 | Original | | 610427-CD1 | |
| Myst III: Exile (Disc 1) | PC | 1.2 | Original, Rerelease | | 610427-CD1A, 650331-CD1 | |
| Myst III: Exile (Disc 2) | PC | 1.2 | Original, Rerelease | | 610427-CD2A, 650331-CD2 | |
| Myst III: Exile (Disc 3) | PC | 1.2 | Original, Rerelease | | 610427-CD3A, 650331-CD3 | |
| Myst III: Exile (Disc 4) | PC | 1.2 | Original, Rerelease | | 610427-CD4A, 650331-CD4 | |
| Myst III: Exile v1.2 Update | PC | | Original | | | |
| Myst IV: Revelation | XBOX | | Original | | US-074 | |
| Myst IV: Revelation | PC | 1.3.0 | 25th Anniversary Collection | | | |
| Myst V: End of Ages | PC | 1.0 | 25th Anniversary Collection | | | |
| Myst V: End of Ages | PC | 1.0 | Limited Edition | | 682523-DVD | |
| Myst V: End of Ages (Disc 1) | PC | | Original | | 682523-CD1 | |
| Myst V: End of Ages (Disc 2) | PC | | Original | | 682523-CD2 | |
| Myst V: End of Ages (Disc 3) | PC | | Original | | 682523-CD3 | |
| Myst: Masterpiece Edition | PC | | 10th Anniversary DVD Edition | | 651116-DVD1 | |
| Myst: Masterpiece Edition (Digital Press Kit) | PC | | Press Kit | | | |
| Myst: Masterpiece Edition | PC | 1.0 | Rerelease | | | |
| Myst: Masterpiece Edition | PC | 1.0 | Original | | 054761-CD | |
| Myst: Masterpiece Edition | PC | 1.0 | Original | | 054761-CD | |
| Myst: Masterpiece Edition | PC | 1.0 | 10th Anniversary DVD Edition | | 651116-DVD1 | |
| Mystaria: The Realms of Lore | SS | 1.000 | Original | | 81300 | |
| Mysteries in Paradise | PC | 1.0.0B | Original | | | |
| Mysterious Adventures: 6-Pack Mysterious Adventures: 6 Complete Games! | PC | | Original | | P/N: 127507 | |
| The Mysterious City: Cairo / The Mysterious City: Vegas Mystery City Adventures: Cairo / Vegas | PC | | Original | | P/N: 124836 | |
| Mysterious Journey II (Disc 1) | PC | DPV 1.1 | Original | | PCO399CD | |
| Mysterious Journey II (Disc 2) | PC | DPV 1.1 | Original | | PCO339CD | |
| Mysterious Journey II (Disc 3) | PC | DPV 1.1 | Original | | PCO399CD | |
| Mysterious Song | PCE | | Unlicensed (Rerelease) | | FCD0001 | |
| Mysterious Song | PCE | | Unlicensed | | FCD0001 | |
| Mystery 4 Pack | PC | | Original | | | |
| Mystery 4 Pack: Volume 2 | PC | | Original | | | |
| Mystery 5 Collection (Disc 1) | PC | ARV 1.0 | Original | | DVD769CD | |
| Mystery 5 Collection (Disc 2) | PC | ARV 1.0 | Original | | | |
| Mystery Adventure Pack (Disc 1) | PC | | Original | | 1000-10805_CD1 | |
| Mystery Adventure Pack (Disc 2) | PC | | Original | | 1000-10805_CD2 | |
| Mystery Case Files: 13th Skull | PC | | Rerelease | | 33387010US | |
| Mystery Case Files: 13th Skull | PC | | Collector's Edition | | 33363101US | |
| Mystery Case Files: Dire Grove | PC | | Collector's Edition | | 35789.101.US | |
| Mystery Case Files: Dire Grove / Mystery Chronicles: Murder Among Friends | PC | | The Best of Big Fish Games | | | |
| Mystery Case Files: Huntsville | PC | 1.6a | Original | | 35357.101.US | |
| Mystery Case Files: Madame Fate | PC | | Rerelease | | 35541.102.US | |
| Mystery Case Files: Prime Suspects | PC | | Rerelease | | 35361.102.US | |
| Mystery Case Files: Ravenhearst | PC | | Rerelease | | 35419.101.US | |
| Mystery Case Files: Ravenhearst | PC | | Original | | 35419.101.US | |
| Mystery Case Files: Ravenhearst / Hidden Expedition: Amazon | PC | | The Best of Big Fish Games | | | |
| Mystery Case Files: Return to Ravenhearst | PC | 1.0.0.0 | Original | | 35743.101.US | |
| Mystery Case Files: Shadow Lake Mystery Case Files 9: Shadow Lake with Lea Thompson | PC | | Collector's Edition | | 33432010US | |
| Mystery Case Files: Shadow Lake / Cursed Memories: Secret of Agony Creek | PC | | Original | | 33461010US | |
| Mystery Case Files: The Malgrave Incident | WII | | Original | | RVL-SFIE-USA-B0 | |
| Mystery Case Files: The Malgrave Incident | WII | | Demo | | RVL-DAVE-USA-B0 | |
| Mystery Chronicles: Murder Among Friends | PC | | Original | | 35747.101.US | |
| The Mystery Collection | PC | | Original | | | |
| Mystery Legends: Beauty & the Beast | PC | | Collector's Edition | | 33389010US | |
| Mystery Legends: Sleepy Hollow | PC | 1.01 | Original | | 02-5602-10 | |
| Mystery Legends: The Phantom of the Opera | PC | | Collector's Edition (Rerelease) | | 33383010US | |
| Mystery Legends: The Phantom of the Opera | PC | | Collector's Edition | | 33383010US | |
| Mystery Masterpiece: The Moonstone | PC | 1.0 | Collector's Edition | | 02-0309-10 | |
| Mystery Masters | PC | | Original | | | |
| Mystery Masters Volume 2 | PC | | Original | | | |
| Mystery Masters: Mystery 6 Pack | PC | | Original | | | |
| Mystery Masters: Supernatural Stories (Disc 1) Mystery Masters: Supernatural Stories Collection | PC | | Collector's Edition | | 38800_DVD1 | |
| Mystery Masters: Supernatural Stories (Disc 2) Mystery Masters: Supernatural Stories Collection | PC | | Collector's Edition | | 38800_DVD2 | |
| Mystery Masters: The Lake House: Children of Silence | PC | | Collector's Edition | | | |
| Mystery Masters: The Secret Stones Collection | PC | | Original | | | |
| Mystery Masters: Treasures of Mystery Collection | PC | | Original | | | |
| Mystery Masters: Twisted Lands: Shadow Town and Stray Souls: Dollhouse Story: 6 Pack | PC | | Original | | | |
| Mystery Masters: Twisted Tales | PC | | Collector's Edition | | | |
| Mystery of Mortlake Mansion: 3 Game Pack | PC | | Cosmi | | CDR176D1, SJ032011 | |
| The Mystery of the Druids (Installation) | PC | 1.0.2.26 | Original | | CDR7045/US2 | |
| The Mystery of the Druids (The Present) | PC | 1.0.2.26 | Original | | CDR7045/US2 | |
| The Mystery of the Druids (The Past) | PC | 1.0.2.26 | Original | | CDR7045/US2 | |
| The Mystery of the Mummy | PC | 1.0 | Original | | PC39020CD DPV1.0 | |
| The Mystery of the Mummy | PC | 1.0 | Original | | | |
| The Mystery of Tooltown | PC | | Original | | | |
| Mystery P.I.: Lost in Los Angeles | PC | 1.0.0.2 | Original | | MPLL 09-00331 10/11 12-00125 | |
| Mystery P.I.: Stolen in San Francisco | PC | | Original | | MPSF-10-00700 11/10 10-00192 | |
| Mystery P.I.: The Curious Case of Counterfeit Cove | PC | | Original | | MPCC-11-01118 12/11 12-00102 | |
| Mystery P.I.: The Curious Case of Counterfeit Cove | PC | 1.0.0.42 | Original | | MPCC-11-01122 06/12 12-00164 | |
| Mystery P.I.: The London Caper | PC | | Rerelease | | MPLC-10-00500 05/10 10-00145 | |
| Mystery P.I.: The London Caper | PC | | Original | | MPLC-10-00500 05/10 10-00145 | |
| Mystery P.I.: The Lottery Ticket | PC | | Original | | | |
| Mystery P.I.: The Lottery Ticket | PC | 1.0.0.5 | Rerelease | | 0227 12/08 08-00124 | |
| Mystery P.I.: The Lottery Ticket | PC | 1.0.0.5 | Rerelease | | 0227 12/08 08-00124, P/N: 125329 | |
| Mystery P.I.: The New York Fortune | PC | | Original | | MPNY-09-00167 8/09 09-00256 | |
| Mystery P.I.: The Vegas Heist | PC | 1.0.0.3 | Original | | 0136 12/08 08-00143 | |
| Mystery Pack | PC | | Encore | | 31760-CD | |
| Mystery Solitaire: Secret Island Mystery Quest: Secret Island | PC | 1.0.0.9 | Original | | | |
| Mystery Trackers: Black Isle | PC | | Collector's Edition | | 33420010US | |
| The Mystery Trio | PC | | Original | | P/N 6010604-CD | |
| Mystery Vault | PC | 1.0 | Original | | 02-9556-10 | |
| Mysteryville | PC | | Original | | 00120.101.US | |
| Mysteryville 2 | PC | | Original | | | |
| Mystic Heroes | GC | | Original | | DL-DOL-GBHE-USA | |
| Mystic Heroes | PS2 | 1.01 | Original | | SLUS-20521 | |
| Mystic Midway: Phantom Express | CDI | | Original, Demonstration Disc | | 310-690-247-2, 310690247-2 | |
| Mystic Towers | PC | 1.11 | Rerelease | | P/N 7088 | |
| Mystic Towers | PC | 1.11 | Original | | | |
| Mystical Ninja Goemon Zero 冒険時代活劇ゴエモン | PS2 | 1.00 | Beta | | | |
| Nancy Drew: Alibi in Ashes Nancy Drew: Mystery #25: Alibi in Ashes | PC | 1.0 | Special 25th Edition | | HER60083-1 | |
| Nancy Drew: Curse of Blackmoor Manor The 3D Adventures of Nancy Drew: Mystery 11: Curse of Blackmoor Manor | PC | 1.0 | Original | | 26051CD | |
| Nancy Drew: Curse of Blackmoor Manor Nancy Drew: Mystery #11: Curse of Blackmoor Manor | PC | 1.01 | Nancy Drew: Ultimate Dare | | 26051CDB | |
| Nancy Drew: Danger by Design (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #14: Danger by Design | PC | 1.0 | Nancy Drew: Double Dare 5 | | HER00061-1.1 | |
| Nancy Drew: Danger by Design (Disc 2) (Data CD) Nancy Drew: Mystery #14: Danger by Design | PC | 1.0 | Nancy Drew: Double Dare 5 | | HER00061-1.2 | |
| Nancy Drew: Danger on Deception Island Nancy Drew: Mystery #9: Danger on Deception Island | PC | 1.0 | Original | | 25096CDSL | |
| Nancy Drew: Danger on Deception Island Nancy Drew: Mystery #9: Danger on Deception Island | PC | 1.1V | Nancy Drew: Triple Threat 2 | | HER20066-1 | |
| Nancy Drew: Ghost Dogs of Moon Lake Nancy Drew: Mystery #7: Ghost Dogs of Moon Lake | PC | 1.0 | Nancy Drew: Triple Threat 2 | | HER20052-1 | |
| Nancy Drew: Ghost Dogs of Moon Lake Nancy Drew: Mystery #7: Ghost Dogs of Moon Lake | PC | 1.0 | Original | | 24493CDSL | |
| Nancy Drew: Ghost Dogs of Moon Lake Nancy Drew: Mystery #7: Ghost Dogs of Moon Lake | PC | 1.1 | | | 24493CD1A | |
| Nancy Drew: Ghost of Thornton Hall Nancy Drew: Mystery #28: Ghost of Thornton Hall | PC | 1.0 | Original | | HER60086-1 | |
| Nancy Drew: Last Train to Blue Moon Canyon (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #13: Last Train to Blue Moon Canyon | PC | 1.0 | Nancy Drew: Ultimate Dare | | 26742CD1, 26742CD1A | |
| Nancy Drew: Last Train to Blue Moon Canyon (Disc 2) (Data CD) Nancy Drew: Mystery #13: Last Train to Blue Moon Canyon | PC | 1.0 | Nancy Drew: Ultimate Dare | | 26742CD2, 26742CD2A | |
| Nancy Drew: Legend of the Crystal Skull (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #17: Legend of the Crystal Skull | PC | 1.1 | Original | | HER00065-1.1 | |
| Nancy Drew: Legend of the Crystal Skull (Disc 2) (Data CD) Nancy Drew: Mystery #17: Legend of the Crystal Skull | PC | 1.1 | Original | | HER00065-1.2 | |
| Nancy Drew: Message in a Haunted Mansion / Samantha Swift and the Hidden Roses of Athena Mystery & Adventure 2-Pack | PC | | Original | | | |
| Nancy Drew: Ransom of the Seven Ships (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #20: Ransom of the Seven Ships | PC | 1.0 | Original | | HER00072-1.1 | |
| Nancy Drew: Ransom of the Seven Ships (Disc 2) (Data CD) Nancy Drew: Mystery #20: Ransom of the Seven Ships | PC | 1.0 | Original | | HER00072-1.2 | |
| Nancy Drew: Secret of the Old Clock Nancy Drew: Mystery #12: Secret of the Old Clock | PC | 1.0 | Nancy Drew: Ultimate Dare | | 26741CDC | |
| Nancy Drew: Secret of the Scarlet Hand Nancy Drew: Mystery 6: Secret of the Scarlet Hand | PC | 1.0 | Original | | 24451CDSL | |
| Nancy Drew: Secret of the Scarlet Hand Nancy Drew: Mystery 6: Secret of the Scarlet Hand | PC | 1.0a | Original | | 24451CD1A | |
| Nancy Drew: Secret of the Scarlet Hand Nancy Drew: Mystery #6: Secret of the Scarlet Hand | PC | 1.1 | Nancy Drew: Triple Threat | | HER61076-1.3 | |
| Nancy Drew: Shadow at the Water's Edge (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #23: Shadow at the Water's Edge | PC | 1.0 | Original | | HER60079-1.1 | |
| Nancy Drew: Shadow at the Water's Edge (Disc 2) (Data CD) Nancy Drew: Mystery #23: Shadow at the Water's Edge | PC | 1.0 | Original | | HER60079-1.2 | |
| Nancy Drew: The Captive Curse Nancy Drew: Mystery #24: The Captive Curse | PC | 1.0 | Original | | HER60082-1 | |
| Nancy Drew: The Creature of Kapu Cave (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #15: The Creature of Kapu Cave | PC | 1.0 | Original, Nancy Drew: Double Dare 5 | | HER00062-1.1 | |
| Nancy Drew: The Creature of Kapu Cave (Disc 2) (Data CD) Nancy Drew: Mystery #15: The Creature of Kapu Cave | PC | 1.0 | Original, Nancy Drew: Double Dare 5 | | HER00062-1.2 | |
| Nancy Drew: The Deadly Device Nancy Drew: Mystery #27: The Deadly Device | PC | 1.0 | Original | | HER60085-1 | |
| Nancy Drew: The Final Scene Nancy Drew: Mystery #5: The Final Scene | PC | 1.0 | Original | | PCO337CD | |
| Nancy Drew: The Final Scene Nancy Drew: Mystery #5: The Final Scene | PC | 1.1 | Nancy Drew: Triple Threat | | HER61076-1.2 | |
| Nancy Drew: The Haunted Carousel Nancy Drew: Mystery #8: The Haunted Carousel | PC | 1.0 | Nancy Drew: Triple Threat 2 | | HER20060-1 | |
| Nancy Drew: The Phantom of Venice (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #18: The Phantom of Venice | PC | 1.0 | Original | | HER00068-1-1 | |
| Nancy Drew: The Phantom of Venice (Disc 2) (Data CD) Nancy Drew: Mystery #18: The Phantom of Venice | PC | 1.0 | Original | | HER00068-1-2 | |
| Nancy Drew: The Secret of Shadow Ranch Nancy Drew: Mystery 10: The Secret of Shadow Ranch | PC | 1.0 | Original | | 25853CDSL | |
| Nancy Drew: The Secret of Shadow Ranch Nancy Drew: Mystery #10: The Secret of Shadow Ranch | PC | 1.01 | Nancy Drew: Ultimate Dare | | 25853CDB | |
| Nancy Drew: The Shattered Medallion Nancy Drew: Mystery #30: The Shattered Medallion | PC | 1.0 | Original | | HER60088-1 | |
| Nancy Drew: The Silent Spy Nancy Drew: Mystery #29: The Silent Spy | PC | 1.0 | Original | | HER60087-1 | |
| Nancy Drew: The White Wolf of Icicle Creek (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #16: The White Wolf of Icicle Creek | PC | 1.0 | Original | | HER00063-1.1 | |
| Nancy Drew: The White Wolf of Icicle Creek (Disc 2) (Data CD) Nancy Drew: Mystery #16: The White Wolf of Icicle Creek | PC | 1.0 | Original | | HER00063-1.2 | |
| Nancy Drew: Tomb of the Lost Queen Nancy Drew: Mystery #26: Tomb of the Lost Queen | PC | 1.0 | Original | | HER60084-1 | |
| Nancy Drew: Trail of the Twister (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #22: Trail of the Twister | PC | 1.0 | Original | | HER60077-1.1 | |
| Nancy Drew: Trail of the Twister (Disc 2) (Data CD) Nancy Drew: Mystery #22: Trail of the Twister | PC | 1.0 | Original | | HER60077-1.2 | |
| Nancy Drew: Treasure in the Royal Tower Nancy Drew: Mystery #4: Treasure in the Royal Tower | PC | 2.0 | Nancy Drew: Triple Threat | | HER61076-1.1 | |
| Nancy Drew: Treasure in the Royal Tower Nancy Drew: Mystery #4: Treasure in the Royal Tower | PC | 3.0 | Rerelease | | HER20049-1 | |
| Nancy Drew: Warnings at Waverly Academy (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #21: Warnings at Waverly Academy | PC | 1.0 | Original | | HER00074-1.1 | |
| Nancy Drew: Warnings at Waverly Academy (Disc 2) (Data CD) Nancy Drew: Mystery #21: Warnings at Waverly Academy | PC | 1.0 | Original | | HER00074-1.2 | |
| Nickelodeon Rugrats Mystery Adventures: Featuring "The Case of the Missing Pacifier" | PC | | Original | | RRM7AE-CD1 | |
| Nightfall Mysteries | PC | 1.0 | Original | | 02-1054-10 | |
| Nightfall Mysteries: Fright Pack | PC | 1.0 | Original | | 02-1658-10 | |
| Princess Abigail: The Mystery of the Missing Princess The Mystery of the Missing Princess | PC | | Original | | | |
| Private Eye Mysteries | PC | | Original | | CDRM1064400 | |
| PuppetShow: Mystery of Joyville / PuppetShow: Souls of the Innocent | PC | | The Best of Big Fish Games | | | |
| PuppetShow: Mystery of Joyville / PuppetShow: Souls of the Innocent | PC | | Rerelease | | 33372101US | |
| The Quaddle Family Mysteries 1: The Case of the Scarce Scarab: Lobby / Kitchen | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 2: The Case of the Scarce Scarab: Garden | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 2: The Case of the Scarce Scarab: Garden | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 3: The Case of the Scarce Scarab: Parlor / Family Room | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 1: The Case of the Scarce Scarab: Lobby / Kitchen | PSX | | Original | | LSP-060101 … | |
| The Quaddle Family Mysteries 2: The Case of the Scarce Scarab: Garden | PSX | | Original | | LSP-060102 … | |
| The Quaddle Family Mysteries 3: The Case of the Scarce Scarab: Parlor / Family Room | PSX | | Original | | LSP-060103 … | |
| realMyst | PC | 1.0 | Original | | 380711-CD | |
| realMyst: Masterpiece Edition | PC | 2.2.1 | 25th Anniversary Collection | | | |
| Reel Deal Slots: Mystic Forest (Disc 1) | PC | 1.0 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 1) | PC | 1.1 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 1) | PC | 1.3 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 1) | PC | 2.0 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 2) | PC | 1.0 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 2) | PC | 1.1 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 2) | PC | 1.3 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 2) | PC | 2.0 | Original | | | |
| Return to Mysterious Island (Disc 1) | PC | 1.0 | Original | | PCO422CD | |
| Return to Mysterious Island (Disc 2) | PC | 1.0 | Original | | PCO422CD | |
| Riven: A Sequência de Myst (Disc 1) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 2) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 3) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 4) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: The Sequel to Myst | PC | | Original | | | |
| Riven: The Sequel to Myst | PC | 1.0 | Demo | | | |
| Riven: The Sequel to Myst | PC | 1.2 | 10th Anniversary DVD Edition | | 651116-DVD2 | |
| Riven: The Sequel to Myst | PC | 1.2.2 | 25th Anniversary Collection | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | | Rerelease | | | |
| Riven: The Sequel to Myst (Disc 1) | PSX | | Original | | SLUS-00535 | |
| Riven: The Sequel to Myst (Disc 1) | PC | | | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0 | Original | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0 | Original | | 1822114 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0 | Original | | 1822114 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD1 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Original | | 1822115 | |
| Riven: The Sequel to Myst (Disc 2) | PSX | | Original | | SLUS-00563 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Rerelease, Ages of Myst | | 650324-CD2 | |
| Riven: The Sequel to Myst (Disc 2) | PC | 1.0 | Original | | 1822115 | |
| Riven: The Sequel to Myst (Disc 2) | PC | 1.03 | Rerelease | | | |
| Riven: The Sequel to Myst (Disc 3) | PSX | | Original | | SLUS-00564 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.0 | Original | | 1822116 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.0 | Original | | 1822116 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD3 | |
| Riven: The Sequel to Myst (Disc 4) | PC | | Original | | 1822117 | |
| Riven: The Sequel to Myst (Disc 4) | PSX | | Original | | SLUS-00565 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.0 | Original | | 1822117 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD4 | |
| Riven: The Sequel to Myst (Disc 5) | PC | | Original | | 1822118 | |
| Riven: The Sequel to Myst (Disc 5) | PSX | | Original | | SLUS-00580 | |
| Riven: The Sequel to Myst (Disc 5) | PC | | Original | | | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.0 | Original | | 1822118 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD5 | |
| The Riven: The Sequel to Myst + Journeyman Project 3: Legacy of Time | PC | | | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Playable Demo) | PC | 0.99 | Demo | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3E-USA | |
| Scooby-Doo! Mystery Mayhem | PS2 | 1.00 | Original | | SLUS-20701 | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| The Smelly Mystery | PC | 1.0 | Original | | 04-12328CD | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Demo: Special Limited Edition | | 647230 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Star Wars: Jedi Knight: Dark Forces II | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Dark Forces II: Ambush at Altyr 5 | PC | 1.0 | Demo: Bundle Version OEM | | 647030, CD-C95-990-E | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Original | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061833 | |
| Starshine Legacy: Episode 1: Mystery of the Soulriders | PC | | Original | | US-61-0603 04 | |
| Strange Cases: The Tarot Card Mystery / Strange Cases: The Lighthouse Mystery | PC | | The Best of Big Fish Games | | 33364101US | |
| Surface: Mystery of Another World | PC | | Collector's Edition | | 33418010US | |
| Thinkin' Things: Sky Island Mysteries | PC | 1.0 | Original | | | |
| Titanic Mystery | WII | | Original | | RVL-STME-USA-B0 | |
| Tokobot Plus: Mysteries of the Karakuri | PS2 | 1.01 | Original | | SLUS-21471 | |
| The Treasures of Mystery Island 2: The Gates of Fate | PC | | Original | | | |
| The Treasures of Mystery Island | PC | | Original | | | |
| The Truth is Out There: Mystery Adventure Pack | PC | | Original | | UI-00743-01 | |
| Ultimate Mystery Collection | PC | | Ultimate Mystery & Adventure Collection | | | |
| Uncle Albert's Mysterious Island | PC | | Original | | | |
| Uru: The Path of the Shell Myst: Uru Expansion Pack: The Path of the Shell | PC | | Original | | 652021-CD | |
| Vampire Mansion: A Linda Hyde Mystery | PC | | Collector's Edition | | | |
| VeggieTales: The Mystery of Veggie Island | PC | | Original | | P/N 10177 | |
| Venice Under Glass: A Basil Baker Mystery Adventure: Screen Saver Day 1 | PC | | | | | |
| Who Stole Hanukkah?! The Great Interactive Mystery Game מי גנב את חנוכה?! משחק הרפתקאות אינסראקסיבי | PC | | Original | | | |
| The Wizard's Pen / Mystery P.I.: The Lottery Ticket | PC | | Original | | 0288 3/09 09-00227 | |