Region | Title | System | Version | Edition | Languages | Serial | Status |
| Buzz Aldrin's Race into Space | PC | | | | | |
| Explorations of Space | CDI | | | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | 2.0 | | | SANSARL-01 | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | CD 7011 SPI | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Angry Birds Space | PC | 1.2.2 | Angry Birds Triple Pack | | P/N: CDR276D1 | |
| Dead Space 3 | PS3 | 01.00 | Beta | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| FreeSpace 2: Colossus | PC | | Bundle Version Logitech WingMan Force 3D Joystick OEM | | CD-W581948-L4ME | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | PC | Rev A | Bundle Version OEM | | RVL 13-004-073 | |
| Descent: FreeSpace: The Great War | PC | 1.06 | Bundle Version OEM (CD-ROM) | | CD-C95-999-DKE | |
| Descent: FreeSpace: The Great War | PC | 1.04 | Bundle Version OEM (DVD-ROM) | | CD-DVD-273-IBE | |
| Descent: FreeSpace: The Great War | PC | 1.06 | Bundle Version OEM (DVD-ROM) | | CD-DVD-273-GPE | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 Rev.1 | |
| Strange Adventures in Infinite Space | PC | | Cheapass Games | | | |
| Space Rangers | PC | 1.7.2 | Cinemaware Marquee | | 02-1506-12 | |
| Space Invaders | PC | | Covermount | | | |
| Where in Space Is Carmen Sandiego? | PC | | Deluxe Edition | | 4921820 | |
| Space Ace | MCD | | Demo | | | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| Star Trek: Deep Space Nine: The Fallen | PC | 11-2000-a | Demo | | | |
| Toonstruck / Subspace | PC | | Demo | | | |
| Descent: FreeSpace: Silent Threat | PC | 1.06 | Dual Jewel, The Great War & Silent Threat bundle | | CD-C95-891-1 | |
| Descent: FreeSpace: The Great War (Disc 1) | PC | 1.06 | Dual Jewel, The Great War & Silent Threat Bundle | | CD-C95-273-2 | |
| Descent: FreeSpace: The Great War (Disc 2) | PC | 1.06 | Dual Jewel, The Great War & Silent Threat Bundle | | CD-C95-273-3 | |
| Dead Space 2 | PS3 | 01.00 | Greatest Hits | | BLUS-30717 … | |
| FreeSpace 2 | PC | 1.00 | Interactive Demo | | CD-C95-1048-D | |
| Space Colony | PC | | Interactive Demo | | | |
| Dead Space 3 (Disc 1) | PC | | Limited Edition | | 1983703301 | |
| Dead Space 3 (Disc 1) | XBOX360 | | Limited Edition | | EA-2461 | |
| Dead Space 3 (Disc 2) | XBOX360 | | Limited Edition | | EA-2461 | |
| Space Engineers | PC | | Limited Edition | | | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| Dead Space 2 데드 스페이스 2: 리미티드 에디션 | PS3 | 01.00 | Limited Edition, Collector's Edition | | BLKS 20260 … | |
| Americans in Space | VIS | | Original | | 25-6203 | |
| Army Men: Toys in Space | PC | 1.0 | Original | | PCD-5043-001 | |
| Boiler Plate Special Strange Adventures in Infinite Space / Dr. Blob's Organism / Big Box of Blox | MAC | | Original | | | |
| Creatures: Raised in Space | PSX | | Original | | SLUS-01553 | |
| Dead Space | PC | 1.0.0.222 | Original | | 1904307 | |
| Dead Space 2 (Disc 1) | PC | 1.0 | Original | | 1953907 | |
| Dead Space 2 (Disc 2) | PC | 1.0 | Original | | 1953917 | |
| Dead Space: Extraction | WII | | Original | | RVL-RZJE-USA-B0 | |
| Descent: FreeSpace: Silent Threat | PC | 1.04 | Original | | CD-C95-891-0 | |
| Descent: FreeSpace: The Great War (Disc 1) | PC | 1.00 | Original | | CD-C95-273-0 | |
| Descent: FreeSpace: The Great War (Disc 2) | PC | 1.00 | Original | | CD-C95-273-1 | |
| The Dinonauts: Adventures in Space Dinonauts: Animated Adventures in Space! | PC | | Original | | | |
| Elmer's Cut & Build 3D: Spacestation & Hometown USA | PC | | Original | | CD-EST001 | |
| FreeSpace 2 (Disc 1) | PC | | Original | | CD-W58-1048-0 | |
| FreeSpace 2 (Disc 2) | PC | | Original | | CD-W58-1048-1 | |
| FreeSpace 2 (Disc 3) | PC | | Original | | CD-W58-1048-2 | |
| The Garfield Show: Threat of the Space Lasagna | WII | | Original | | RVL-SG7E-USA-B0 | |
| Jesus in Space | PC | 1.1 | Original | | | |
| Looney Tunes: Space Race | PS2 | 1.00 | Original | | SLUS 20352 | |
| Looney Tunes: Space Race | DC | 1.000 | Original | | T-15116N | |
| Microsoft My Personal Tutor: 1st & 2nd Grade Math Skills: Sky's Space Station Voyage | PC | | Original | | X03-70832 | |
| Microsoft Space Simulator | PC | 1.0 | Original | | 0196 Part No. 64730 Disc Assy. 165-087-002 | |
| Miracle Space Race | PSX | | Original | | SLUS-01556 | |
| Mobile Suit Gundam: Encounters in Space | PS2 | 1.01 | Original | | SLUS-20740 | |
| Sam & Max: Beyond Time and Space | PC | | Original | | 27898CD | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YE-USA-B0 | |
| Space Ace | PC | | Original | | | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | AJCD | | Original | | | |
| Space Ace | 3DO | | Original | | | |
| Space Ace | 3DO | RE-1 | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (PC and Compatibles) Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| Space Bucks | PC | | Original | | | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Camp | WII | | Original | | RVL-RIYE-USA | |
| Space Channel 5 | DC | 1.000 | Original | | 51051 | |
| Space Channel 5: Special Edition (Disc 1) | PS2 | 1.00 | Original | | SLUS 20806 | |
| Space Channel 5: Special Edition (Disc 2) | PS2 | 1.01 | Original | | SLUS 20807 | |
| Space Chimps | XBOX360 | | Original | | BT-2004 Version: 1. | |
| Space Chimps | WII | | Original | | RVL-RP9E-USA | |
| Space Chimps | PS2 | 1.03 | Original | | SLUS 21783 | |
| Space Colony | PC | | Original | | | |
| Space Dudes | PC | | Original | | | |
| Space Griffon VF-9 | PSX | | Original | | SLUS-00153 | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | | Original | | 7373 | |
| Space Hulk: Vengeance of the Blood Angels | PSX | | Original | | SLUS-00205 | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H | |
| Space Invaders | PSX | | Original | | SLUS-00928 | |
| Space Invaders | PC | 1.0 | Original | | 1000916.101.US | |
| Space Invaders Extreme | PSP | 1.00 | Original | | ULUS-10346 | |
| Space Invaders XL | NUON | | Original | | 11109 | |
| Space Jam | PSX | | Original | | SLUS-00243 | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam | SS | 1.000 | Original | | T-8125H | |
| Space Pirates | 3DO | | Original | | ALG595001 | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.0 | Original | | S329430 | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest: Collection Series (Disc 1) | PC | | Original | | | |
| Space Quest: Collection Series (Disc 2) | PC | | Original | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Space Raiders | GC | | Original | | DL-DOL-GIJE-USA | |
| Space Shot | PSX | | Original | | SLUS-01308 | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | 3DO | | Original | | | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Siege | PC | 1.0 | Original | | | |
| Space Sirens | PC | | Original | | SKU: UN017 | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Spacebound Space Bound | PC | | Original | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| Spaceship Warlock | PC | 1.1.3 | Original | | | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| Star Trek: Deep Space Nine: Dominion Wars | PC | 1.00 | Original | | | |
| Star Trek: Deep Space Nine: The Fallen | PC | 1.0 | Original | | 0-671-57663-1, S5293110 | |
| Stardate 2410.2: Crusade in Space: The Zardula Incursion | PC | 1.16 | Original | | ROW-10602 | |
| StarFlyers Alien Space Chase | PC | 1.0 | Original | | 380853A-CD | |
| Starwinder: The Ultimate Space Race | PSX | | Original | | SLUS-00094 | |
| Timeless Math 5: Space Flight Rescue | PSX | | Original | | LSP-040510 … | |
| Tonka Space Station | PSX | | Original | | SLUS-01007 | |
| Tonka Space Station | PC | | Original | | Product# 99583 | |
| Video Cube: Space | PC | | Original | | VDC344AE-CD | |
| Warhammer 40,000: Space Marine | PS3 | 01.01 | Original | | BLUS-30432 | |
| Warhammer 40,000: Space Marine (Disc 1) | PC | | Original | | | |
| Warhammer 40,000: Space Marine (Disc 2) | PC | | Original | | | |
| Weird Worlds: Return to Infinite Space | PC | 1.0 | Original | | | |
| Worms: A Space Oddity | WII | | Original | | RVL-RWME-USA | |
| XF5700 Mantis: Experimental Fighter XF5700 Mantis: Experimental Spacefighter | PC | | Original | | 9019CDR | |
| Space Adventure: With Buzz Aldrin & Tom McDonough | MAC | | Original, Bundle Version Apple OEM | | CDRM1239480 | |
| Space Ace | CDI | | Original, Demonstration Disc | | 310-690-059-2, 310690059-2 | |
| Rocky Racers Space Racers | PC | | Pocketware | | #5 | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Space Station Tycoon | WII | | Prototype | | | |
| Descent: FreeSpace: Silent Threat | PC | 1.04 | Rerelease | | CD-C95-1115-0 | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Invaders | PSX | | Review | | | |
| FreeSpace 2 (Disc 1) | PC | | Sci-Fi Sim of the Year Edition | | CD-W58-1176-0 | |
| FreeSpace 2 (Disc 2) | PC | | Sci-Fi Sim of the Year Edition | | CD-W58-1176-1 | |
| FreeSpace 2 (Disc 3) | PC | | Sci-Fi Sim of the Year Edition | | CD-W58-1176-2 | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| 3D Ultra Mini Golf Adventures: Space | PC | | Taco Bell | | | |
| Spaceship Warlock | PC | 1.1.3 "MPC" | Ultimate Game Collection | | | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Army Men: Toys in Space | PC | 1.0 | Value Pack | | PCD-5146-003 | |