Region | Title | System | Version | Edition | Languages | Serial | Status |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| School Tycoon | PC | | Original | | | |
| School Tycoon | PC | v1 | Original | | | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Phonics: Grades 2-3 | PC | v.5 | Original | | 08064 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | MAC | | Original | | 9227 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| The Sci-Fi Collection | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Is Elementary 1 | PSX | | Original | | LSP-990161 … | |
| Science Is Elementary 2 | PSX | | Original | | LSP-990162 … | |
| Science Is Elementary 3 | PSX | | Original | | LSP-990163 … | |
| Scissors 'n' Stones | PC | | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo! | IXL | 1.0.0 | Original | | R9709 | |
| Scooby-Doo! | IXL | 2.0.0 | Original | | R9709 | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scorched Planet | PC | | Original | | | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scorcher | SS | 1.008 | Original | | 81214 | |
| Scorcher | SS | 2.000 | Original | | 81214 | |
| Score 4 | PC | | Original | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| Scrabble | PSX | | Original | | SLUS-00903 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| Scrabble: Crossword Game | MAC | 1.0.0.52 | Original | | P/N 10328-5 | |
| Scramble Cobra | 3DO | | Original | | FZ-SM0404 | |
| Scratches | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLUS-21741 | |
| Sea-Doo Hydro Cross | PSX | | Original | | SLUS-01149 | |
| Seal of the Pharaoh | 3DO | | Original | | FZ-SM1751 | |
| Seaman | DC | 1.001 | Original | | 51048 | |
| Search & Rescue 3 | PC | 1.0.0.0 | Original | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| The Secret of Googol 1: Reshaping Googol: Submarine / Tower | PC | 2.0 | Original | | | |
| The Secret of Googol 1a: Reshaping Googol: The Submarine | PSX | | Original | | LSP-020160 … | |
| The Secret of Googol 1b: Reshaping Googol: The Tower | PSX | | Original | | LSP-020150 … | |
| The Secret of Googol 2: Reshaping Googol: Castle / Ocean | PC | 2.0 | Original | | | |
| The Secret of Googol 2a: Reshaping Googol: The Castle | PSX | | Original | | LSP-020180 … | |
| The Secret of Googol 2b: Reshaping Googol: Under the Ocean | PSX | | Original | | LSP-020170 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PSX | | Original | | LSP-020260 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PSX | | Original | | LSP-020280 … | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PC | 2.0 | Original | | | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PSX | | Original | | LSP-020450 … | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PSX | | Original | | LSP-020570 … | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PSX | | Original | | LSP-020650 … | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PSX | | Original | | LSP-020780 … | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy Seek & Destroy | PC | | Original | | EPSAD01 | |
| Seek and Destroy Seek & Destroy | PC | 1.0 | Original | | J230D | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Bass Fishing 2 | DC | 1.080 | Original | | 51166 | |
| Sega Bass Fishing Duel Bass Fishing Duel: Sega Sports | PS2 | 1.02 | Original | | SLUS 20339 | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega Marine Fishing | DC | 1.001 | Original | | 51096 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally 2 Sega Rally 2: Sega Rally Championship | DC | 1.003 | Original | | 51019 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Sports Tennis | PS2 | 1.01 | Original | | SLUS 20480 | |
| Sega Superstars | PS2 | 1.00 | Original | | SLUS 20999 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| Self Selling Disc | CDI | 01 | Original | | | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Sentient | PSX | | Original | | SCUS-94110 | |
| Sentient | PC | | Original | | | |
| Sentinel Returns | PSX | | Original | | SLUS-00604 | |
| Sentinel Returns | PC | 1.0 | Original | | CDAC-148200 | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Original | | CD-W58-1103-0 | |
| Serious Sam Gold (Disc 1) | PC | 1.05 | Original | | | |
| Serious Sam Gold (Disc 2) | PC | 1.05 | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street Sports | PSX | | Original | | SLUS-01180 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Preschool (Disc 1) (Elmo's Preschool) | PC | 3.1 | Original | | P/N 379663-CD1 | |
| Sesame Street: Elmo's Preschool (Disc 2) (Search & Learn Adventures) | PC | 3.1 | Original | | P/N 379663-CD2 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: My Baby & Me (Disc 1) (Baby & Me) | PC | 1.0 | Original | | SSY744AE-CD1 | |
| Sesame Street: My Baby & Me (Disc 2) (Sesame Street Greatest Hits Sampler) | PC | 1.0 | Original | | SSY744AE-CD2 | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | 3DO | | Original | | | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Seventh Cross Evolution | DC | 1.000 | Original | | T-41301N | |
| Sewer Shark | MCD | | Original | | T-6201 | |
| Sewer Shark | MCD | Rev 1 | Original | | T-6201 | |
| Sex | 3DO | | Original | | | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-0 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-1 | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Shadow Madness (Disc 1) | PSX | | Original | | SLUS-00468 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SLUS-00718 | |
| Shadow Man | PC | | Original | | | |
| Shadow Man | PSX | | Original | | SLUS-00895 | |
| Shadow Man | DC | 1.001 | Original | | T-8106N | |
| Shadow Man | DC | 1.010 | Original | | T-8106N | |
| Shadow Man: 2econd Coming | PS2 | 1.03 | Original | | SLUS-20413 | |
| Shadow Master | PSX | | Original | | SLUS-00545 | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Shadow of the Beast | PCE | | Original | | TGXCD1018 | |
| Shadow of the Beast II | MCD | | Original | | T-113045 | |
| Shadow Tower | PSX | | Original | | SLUS-00863 | |
| Shadow Watch | PC | 1.0 | Original | | | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| Shadowbane | PC | 1.0 | Original | | 650478-CD | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| ShadowGate Classic | PPC | 1.0.0.4 | Original | | 5053626 | |
| Shadowgrounds (Disc 1) | PC | 1.01 | Original | | 000046-CD1 | |
| Shadowgrounds (Disc 2) | PC | 1.01 | Original | | 000046-CD2 | |
| Shakii the Wolf | PC | | Original | | | |
| Shanghai Double Pack | PC | | Original | | | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Shanghai: Triple-Threat | 3DO | | Original | | | |
| Shanghai: Triple-Threat | SS | 1.002 | Original | | T-13001H | |
| Shanghai: True Valor | PSX | | Original | | SLUS-00795 | |
| Shannara | PC | 1.0.0 | Original | | | |
| Shannara | PC | 1.0 | Original | | | |
| Shape Shifter | PCE | | Original | | TGXCD1021 | |
| Shape Shifter | PC | | Original | | | |
| Shari Lewis Lamb Chop's Play-Along! Action Songs | CDI | | Original | | 310690289-2 | |
| SharkPort: Code and Save Transfer Kit | PC | 1.04 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PC | 1.10 | Original | | | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Shattered Steel | PC | 1.03 | Original | | CD-ICD-201-2 | |
| Sheep | PSX | | Original | | SLUS-01298 | |
| Sheep | PC | 1.00.000 | Original | | | |
| Shelley Duvall's It's a Bird's Life | 3DO | | Original | | | |
| Shellshock | PSX | | Original | | SLUS-00031 | |
| Shellshock | SS | 1.000 | Original | | T-7901H | |
| Shenmue (Shenmue Passport) | DC | 1.004 | Original | | 51059 | |
| Shenmue (Disc 2) | DC | 1.003 | Original | | 51059 | |
| Shenmue (Disc 3) | DC | 1.003 | Original | | 51059 | |
| Sherlock Holmes: Consulting Detective | PCE | | Original | | TGXCD1011 | |
| Sherlock Holmes: Consulting Detective: Vol. I | VIS | | Original | | 25-6183 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| Sherlock Holmes: Consulting Detective: Vol. II | VIS | | Original | | 25-6184 | |
| Sherlock Holmes: Consulting Detective: Vol. II | PCE | | Original | | TGXCD1039 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 2) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. III | PC | 4 | Original | | CDRM1061930 | |
| Sherlock Holmes: Nemesis (Disc 1) | PC | 1.00.0777 | Original | | PCO589CD1, SNY 1.0 | |
| Sherlock Holmes: Nemesis (Disc 2) | PC | 1.00.0777 | Original | | PCO589CD2, SNY 1.0 | |
| Shifters | PS2 | 1.02 | Original | | SLUS 20271 | |
| Shining Force CD | MCD | | Original | | 4656 | |
| Shining Force CD | MCD | | Original | | 4656 | |
| Shining Force III | SS | 1.001 | Original | | 81383 | |
| Shining the Holy Ark | SS | 1.003 | Original | | 81306 | |
| Shinobi Legions | SS | 1.000 | Original | | T-2301H | |
| Shipwreckers! | PSX | | Original | | SLUS-00558 | |
| Shivers | PC | 1.02 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Shockwave Assault | SS | 1.000 | Original | | T-5005H | |
| Shockwave Assault (Disc 1) (Shockwave: Invasion Earth) | PSX | | Original | | SLUS-00028 | |
| Shockwave Assault (Disc 2) (Shockwave: Operation Jumpgate) | PSX | | Original | | SLUS-00137 | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | 798707 | |
| Shogun: Total War (Disc 2) | PC | | Original | | 798717, 1224617 | |
| Shogun: Total War: The Mongol Invasion Shōgun: Total War: The Mongol Invasion | PC | 1.00 | Original | | 1430907 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | 1.00 | Original | | 1430717 | |
| Shooting Gallery | PALM | | Original | | | |
| Shopmania | PC | | Original | | P/N 61227-CD | |
| Shox | PS2 | 1.00 | Original | | SLUS-20533 | |
| Shrak Shrak for Quake | PC | 1.0 | Original | | | |
| Shrek 2 | MAC | | Original | | 10700-1CDA | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shrek 2: Team Action | PC | 1.0 | Original | | 32789.101.US | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek Super Party | PS2 | 1.00 | Original | | SLUS 20516 | |
| Shrek the Third: The Search for Arthur | VFLASH | | Original | | 093140(US) | |
| Shrek Treasure Hunt | PSX | | Original | | SLUS-01463 | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | 105907 | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Sid Meier's C.P.U. Bach | 3DO | | Original | | | |
| Sid Meier's Civilization Chronicles (Disc 1) | PC | | Original | | 31074-1.1 | |
| Sid Meier's Civilization Chronicles (Disc 2) | PC | | Original | | 31074-1.2 | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sid Meier's Civilization II | PC | 1.0 | Original | | 0-492-47-101 | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization II: Fantastic Worlds | PC | | Original | | 0-529-47-101 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | Original | | 25766CD2 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | Original | | 25766CD3 | |
| Sid Meier's Civilization III: Play the World | PC | 1.01f | Original | | Part # 24115CD | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Civilization IV: Colonization | PC | | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 1) | PC | 1.7.4.0 | Original | | 31183-1.1 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 2) | PC | 1.7.4.0 | Original | | 31183-1.2 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 3) | PC | 1.7.4.0 | Original | | 31183-1.3 | |
| Sid Meier's Civilization IV: Warlords | PC | 2.0 | Original | | 21966-1 | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | 1015007 | |
| Sid Meier's Pirates! (Disc 1) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD1 | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD2 | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| Sierra Pro Pilot (Disc 1) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot (Disc 2) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot 98 | PC | 1.0 | Original | | | |
| Sierra's School House: English (Disc 1) | PC | | Original | | | |
| Sierra's School House: Math (Disc 1) | PC | | Original | | | |
| Sierra's School House: Math (Disc 2) | PC | | Original | | | |
| Sierra's School House: Science (Disc 1) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Science (Disc 2) | PC | | Original | | 831614230/S161155 | |
| Silent Bomber | PSX | | Original | | SLUS-00902 | |
| Silent Hill 2 (Disc 1) | PC | 1.0 | Original | | Part Number 23429/23435-1 | |
| Silent Hill 2 (Disc 2) | PC | 1.0 | Original | | Part Number 23429/23435-2 | |
| Silent Hill 2 (Disc 3) | PC | 1.0 | Original | | Part Number 23429/23435-3 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | | |
| Silent Hill 3 (Disc 2) | PC | 1.0.0.1 | Original | | S2344320 | |
| Silent Hill 3 (Disc 3) | PC | 1.0.0.1 | Original | | S2344330 | |
| Silent Hill 3 (Disc 4) | PC | 1.0.0.1 | Original | | S2344340 | |
| Silent Hill 3 (Disc 5) | PC | 1.0.0.1 | Original | | S2344350 | |
| Silent Hunter | PC | 1.0.324 | Original | | | |
| Silent Hunter II Silent Hunter II: WWII U-Boat Combat Simulator | PC | 1.00.06 | Original | | 610465-CD | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Original | | 2211110-590004 | |
| Silent Scope | PS2 | 1.00 | Original | | SLUS 20078 | |
| Silent Scope | DC | 1.000 | Original | | T-9507N | |
| Silent Scope 2: Dark Silhouette | PS2 | 1.00 | Original | | SLUS-20243 | |
| Silent Scope 3 | PS2 | 1.00 | Original | | SLUS-20514 | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Silhouette Mirage | PSX | | Original | | SLUS-00728 … | |
| Silkolene Honda Motocross GP | PC | 1.0 | Original | | 13030 | |
| A Silly Noisy House | MAC | | Original | | CDAC 014500 | |
| Silpheed | MCD | | Original | | 4423 | |
| Silpheed: The Lost Planet | PS2 | 1.20 | Original | | SLUS 20085 … | |
| Silver | DC | 1.001 | Original | | T-15108N | |
| Silverload | PSX | | Original | | SLUS-00050 | |
| SimCity 2000 | SS | 1.401 | Original | | T-12601H | |
| SimCity 2000 for Pocket PC | PPC | 1.0 | Original | | | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Original | | 0130-000-0601-A | |
| SimCity 2000 Special Edition | PC | | Original | | 0126-000-0601-A | |
| SimCity 2000 Special Edition | MAC | 1.0 | Original | | 0126-000-0601-A | |
| SimCity 2000: CD Collection | MAC | 1.0 | Original | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity 3000 | MAC | 1.0.557 | Original | | 1500607 | |
| SimCity 3000 | PC | 1.0.557.0 | Original | | 1500107 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | MXB08803894CD1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | MXB08803894CD2 | |
| SimCity 4 (Disc 1) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | 1457307 | |
| SimCity 4 (Disc 2) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | 1457317 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | | Original | | 1474007 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | Original | | 1474007 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| SimCity 4: Rush Hour | PC | 1.0 | Original | | 1472207 | |
| SimCity Enhanced CD-ROM | PC | | Original | | CD-ICD-041-0 | |
| SimClassics: 3 in 1 Pack | PC | | Original | | 0543-000-0601-A | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| SimCoaster | PC | | Original | | 1425707 | |
| SimCopter | PC | 1.0 | Original | | 0077-000-0601-A | |
| SimCopter SimCopter: Fly Missions in the Metropolis | PC | 1.01 | Original | | 0077-000-0601-B | |
| SimEarth: The Living Planet | PCE | | Original | | TGXCD1036 | |
| SimGolf | PC | 1.0 | Original | | 0093-000-0601-A | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| Simon the Sorcerer | PC | 1.00 | Original | | | |
| The Simpsons Skateboarding | PS2 | 1.01 | Original | | SLUS-20114 | |
| The Simpsons Wrestling | PSX | | Original | | SLUS-01227 | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | Original | | S7213210 | |
| The Simpsons: Hit & Run (Disc 2) | PC | 1.0 | Original | | S7213220 | |
| The Simpsons: Hit & Run (Disc 3) | PC | 1.0 | Original | | S7213230 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.932 | Original | | 1472607, 1472610 | |
| The Sims 2 (Disc 2) | PC | 1.0 | Original | | 1472617 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.932 | Original | | 1472610, 1472617 | |
| The Sims 2 (Disc 3) | PC | 1.0 | Original | | 1472627 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | 1472627 | |
| The Sims 2 (Disc 4) | PC | 1.0 | Original | | 1472637 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.932 | Original | | 1472637 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original | | 1536717 | |
| The Sims 2: Celebration! Stuff | PC | 1.8.0.64 | Original | | 1564707 | |
| The Sims 2: Family Fun Stuff | PC | | Original | | 1515807 | |
| The Sims 2: Glamour Life Stuff | PC | 1.5.0.121 | Original | | 1520807 | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | 1536607 | |
| The Sims 2: Happy Holiday Stuff | PC | | Original | | 1527707 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: Holiday Edition (Disc 2) | PC | 1.0.0.1048 | Original | | 1518917 | |
| The Sims 2: Holiday Edition (Disc 3) | PC | 1.0.0.1048 | Original | | 1518927 | |
| The Sims 2: Holiday Edition (Disc 4) | PC | 1.0.0.1048 | Original | | 1518937 | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | 1578207 | |
| The Sims 2: Insider Preview CD | PC | | Original | | 1625207 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | 1578007 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | 1.14.0.72 | Original | | 1578007 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.312 | Original | | 1497007 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.312 | Original | | 1497017 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Pets (Expansion Pack) | MAC | | Original | | 11500-1CDA | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | Original | | 1526317 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims Carnival: BumperBlast | PC | 1.0.10 | Original | | 1586907 | |
| The Sims Online (Disc 1) | PC | 1.0 | Original | | 1436707 | |
| The Sims Online (Disc 2) | PC | 1.0 | Original | | 1436717 | |
| The Sims Online: Sampler Disc | PC | | Original | | 4025407 | |
| The Sims | PC | 1.0 | Original | | 1500807 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Hot Date (Expansion Pack) | MAC | | Original | | 10150-1CDA | |
| The Sims: House Party (Expansion Pack) | PC | 1.0 | Original | | 1431307, 1431317 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1472007 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Original | | 1472017 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | MAC | | Original | | 10430-1CDA | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | MAC | | Original | | 10430-2CDA | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | | Original | | 1640617 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original | | 1459517 | |
| The Sims: Vacation (Expansion Pack) | PC | | Original | | 1448807 | |
| The Sims: Vacation (Expansion Pack) | MAC | | Original | | | |
| SimTheme Park Sim Theme Park | PSX | | Original | | SLUS-01069 | |
| SimTheme Park Sim Theme Park | PC | | Original | | 1403307 | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-A | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-B | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-B | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| SimTown: The Town You Build Yourself! | MAC | | Original | | 0037-000-0601-A, 0037-029-0601-A | |
| SimTunes | PC | | Original | | 0135-000-0601-A | |
| SiN | PC | 1.00 | Original | | 1000076.101.US | |
| SiN | PC | 1.01 | Original | | 1000076.101.US | |
| SiN Gold | MAC | 1.1.1 | Original | | | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.US | |
| Sinbad: Legend of the Seven Seas | PC | 1.0 | Original | | Part # 24755CD | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sinistar: Unleashed | PC | | Original | | | |
| Sinkha | MAC | | Original | | | |
| Sinkha | PC | | Original | | | |
| Skeleton Warriors | PSX | | Original | | SLUS-00209 | |
| Skeleton Warriors | SS | 1.001 | Original | | T-13204 H | |
| Skies of Arcadia (Disc 1) | DC | 1.002 | Original | | 51052 | |
| Skies of Arcadia (Disc 2) | DC | 1.002 | Original | | 51052 | |
| Skin Style | CDI | | Original | | | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Skullmonkeys | PSX | | Original | | SLUS-00601 | |
| Skunny | PC | 1.0 | Original | | P/N 7149 | |
| Skunny Kart Combo | PC | | Original | | | |
| Sky Target | SS | 1.003 | Original | | 81051 | |
| Skydiving Extreme | PSX | | Original | | SLUS-01392 | |
| Slam 'n Jam '95 | 3DO | | Original | | 60140-C | |
| Slam 'n Jam '96 featuring Magic & Kareem | PSX | | Original | | SLUS-00022 | |
| Slam 'n Jam '96 featuring Magic & Kareem: Signature Edition | SS | 1.000 | Original | | T-15902H | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Original | | T162035 | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | | Original | | WTY744AE-CD | |
| Slamscape | PSX | | Original | | SLUS-00080 | |
| Slave Pageant (Game Disc) | PC | | Original | | GC-020 | |
| Slave Pageant (Install Disc) | PC | | Original | | GC-020 | |
| Slave Zero | PC | 1.0 | Original | | 46031-301SZR | |
| Slave Zero | DC | 1.001 | Original | | T-15106N | |
| Slave Zero | DC | 1.002 | Original | | T-15106N | |
| Slayer | 3DO | | Original | | | |
| Sled Storm | PS2 | 1.00 | Original | | SLUS-20363 | |
| Slingo | PC | | Original | | 99310 | |
| Slingo | PC | 1.00 | Original | | 99310 | |