Region | Title | System | Version | Edition | Languages | Serial | Status |
| Ultimate Ride Coaster Deluxe | PC | | Original | | H0919 | |
| Uru: The Path of the Shell Myst: Uru Expansion Pack: The Path of the Shell | PC | | Original | | 652021-CD | |
| Uru: Complete Chronicles (Disc 1) | PC | | Original | | 751830-CD1 | |
| Uru: Complete Chronicles (Disc 1) | PC | | Original | | 652038-CD1 | |
| Urban Chaos | PC | 2.63 | Original | | | |
| Unreal Tournament 2004 (Play Disc) | PC | 3186 | Special Edition, 2 Disc DVD Edition | | Part # 25309DV1, Part # 25812DV1 | |
| Unreal Tournament 2004 (Play Disc) | PC | 3186 | Original | | Part # 25012CD6 | |
| Unreal Tournament 2004 (Play Disc) | PC | 3186 | Original | | Part # 25012CD6 | |
| Unreal Tournament 2004 (Bonus Disc) | PC | | Special Edition, Editor's Choice Edition, 2 Disc DVD Edition | | Part # 25309DV2, Part # 25812DV2, Part # 26019DV2 | |
| Unreal Tournament 2003 (Disc 1) (Play Disc) | PC | 2199 | Rerelease | | Part# 23956CD1B | |
| Unreal Tournament 2003 (Disc 1) (Play Disc) | PC | 2141 | Rerelease | | Part# 23956CD1B | |
| Unreal Tournament (Disc 1) (Game) | PC | 400 | Original, Rerelease | | 04-18115CD1A | |
| Unreal Tournament (Disc 1) (Game) | PC | 400 | Original | | 04-18115CD1 | |
| Unreal Tournament | PC | 428 | Bundle Version Creative Labs OEM | | 04-18115CD | |
| Unreal II: The Awakening (Play Disc) | PC | 1.0 | Original | | Part# 22650CD2 | |
| Unreal II: The Awakening (Play Disc) | PC | | Special Edition | | Part#24929CD3 | |
| Unlucky Panoss | PC | | Original | | | |
| Universe at War: Earth Assault | PC | 1.0 | Original | | | |
| Universal Combat | PC | | Original | | PCO404CD | |
| Ultimate Spider-Man (Disc 1) | PC | 1.0 | Original | | 32857.101.US | |
| Ultimate Ride: Disney Coaster | PC | | | | H6406 | |
| Ultimate Ride: Disney Coaster | PC | | Original | | H6406 | |
| Ultimate Ride | PC | 1.00.000 | Original | | G2939 | |
| Ultimate Body Blows | PC | | Original | | | |
| Ultima IX: Ascension (Disc 2) (Game Disc) | PC | | Ultima Online 7th Anniversary Edition | | 1487227 | |
| Ultima IX: Ascension (Play Disc) | PC | 1.03F, 1.18F | Original, Ultima: Best of Both Worlds: Special Value Edition | | 1051017 | |
| Ultima IX: Ascension (Install Disc) | PC | 1.03F | Original, Dragon Edition | | 1051007 | |
| Ultima IX: Ascension (Game Disc) | PC | 1.03F | Dragon Edition | | 1051017 | |
| UberSoldier (Disc 3) | PC | | Original | | | |