Region | Title | System | Version | Edition | Languages | Serial | Status |
| Uncharted 2: Among Thieves | PS3 | 01.00 | Original, Game of the Year Edition, Game of the Year Edition: Greatest Hits, Uncharted Dual Pack, Not For Resale | | BCUS-98123 … | |
| Untold Legends: Brotherhood of the Blade | PSP | 1.02 | Original, Greatest Hits | | ULUS-10003 | |
| Untold Legends: The Warrior's Code | PSP | 1.02 | Original | | ULUS-10086 | |
| uDraw Studio | WII | | Bundled with uDraw GameTablet | | RVL-SUWE-USA-B0 | |
| uDraw Studio: Instant Artist | WII | | Original | | RVL-SUUE-USA-B0 | |
| UFC Personal Trainer: The Ultimate Fitness System | WII | | Bundled with Leg Strap | | RVL-SU4E-USA-B0 | |
| U.S. Navy Fighters | PC | 1.0 | Original, Not For Resale | | 5441, 7432 | |
| Ultima Collection | PC | 1.02F | CD-ROM Classics, PC Game Bundle | | 1172007 | |
| Ultima IX: Ascension (Disc 1) (Install Disc) | PC | | Ultima Online 7th Anniversary Edition | | 1487217 | |
| Ultima IX: Ascension (Disc 2) (Game Disc) | PC | | Ultima Online 7th Anniversary Edition | | 1487227 | |
| Ultima Online | PC | | Ultima Online 7th Anniversary Edition | | 1487207 | |
| Ultima Underworld I & II Ultima Underworld: The Stygian Abyss / Ultima Underworld II: Labyrinth of Worlds | PC | | CD-ROM Edition | | EA 6718 | |
| The Ultimate Doom | PC | 1.9 | Original | | 04-10333CD | |
| Ultimate Games for Boyz (Disc 1) (Power Rangers: Ninja Storm / Construction City) Power Rangers: Ninja Storm / Construction City | PC | | Original | | P/N: 10392-1 | |
| Ultimate Games for Boyz (Disc 2) (Pokémon: Masters Arena / Dino Island) Pokémon: Masters Arena / Dino Island | PC | | Original | | P/N: 10392-2 | |
| Ultimate Mahjongg 10 | PC | 1.0.0.1 | Original | | P/N: 10302 | |
| Ultimate Mahjongg 20 | PC | | Original | | P/N: 10578 | |
| Ultimate Puzzles 1001 Ultimate Puzzles 1000 | PC | | Original | | P/N: 10420 | |
| Ultimate Ride | PC | 1.00.000 | Original | | G2939 | |
| Ultimate Solitaire 1000 Ultimate Solitaire 1000 Unique Games | PC | 1.1 | Original | | P/N: 10568 | |
| Ultimate Yahtzee | PC | 1.0.0.1 | General Mills | | AM801R1 | |
| Ultrabots | PC | | CD-ROM Classics | | 5389 | |
| Under a Killing Moon (Disc 1) | PC | | Original | | | |
| Under a Killing Moon (Disc 2) | PC | | Rerelease | | | |
| Under a Killing Moon (Disc 2) | PC | | Original | | | |
| Under a Killing Moon (Disc 3) | PC | | Original | | | |
| Under a Killing Moon (Disc 3) | PC | | | | | |
| Under a Killing Moon (Disc 4) | PC | | Original | | | |
| Under a Killing Moon (Disc 4) | PC | | | | | |
| Under Pressure | PC | | Original | | | |
| Unlock the Secrets: Blood | PC | 1.0 | Original | | P/N 7330 | |
| Unreal Unreal Special Version | PC | | Bundle Version Diamond OEM (Demo) | | 75500075-001 | |
| Unreal Gold | PC | 226b | Original, Totally Unreal | | 04-19951CD | |
| Unreal II + Unreal Championship (First Look CD) | PC | | Totally Unreal | | 04-22651CD | |
| Unreal II: The Awakening (Play Disc) | PC | 1.0 | Original | | Part# 22650CD2 | |
| Unreal II: The Awakening (Install Disc) | PC | 1.0 | Original | | Part# 22650CD1 | |
| Unreal Tournament (Disc 1) | PC | 432 | Game of the Year Edition (Rerelease) | | Part# 21160CD1 | |
| Unreal Tournament (Disc 2) | PC | 432 | Game of the Year Edition, Game of the Year Edition (Totally Unreal), Game of the Year Edition (Rerelease) | | 04-21165CD2, Part# 21160CD2 | |
| Unreal Tournament 2003 (Disc 2) | PC | 2107 | Original | | Part# 23956CD2 | |
| Unreal Tournament 2003 (Disc 3) | PC | 2107 | Original | | Part# 23956CD3 | |
| Unreal Tournament 2004 (Play Disc) | PC | 3186 | Original | | Part # 25012CD6 | |
| Uprising 2: Lead and Destroy | PC | 1.0 | Original | | PCD-5022-001 | |
| USA Bass Championship | PC | | Original | | P/N: 10260 | |
| The Ultimate Hoyle Anniversary Collection | PC | 1.0 | Original | | 36450-DVD | |