Region | Title | System | Version | Edition | Languages | Serial | Status |
| System Shock | PC | F1.6C / F1.6S | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 2.0 | Bundle Version Diamond OEM | | 75000203-100 | |
| Solitaire: 50 Complete Games! | PC | 2.0 | Rerelease | | 10-0990-10 | |
| Shrak Shrak for Quake | PC | 2.0 | Rerelease | | | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 2) | PC | 1.7.0.145 | Original, Slim Case | | 1562117 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 1) | PC | 1.7.0.145 | Original, Slim Case | | 1562107 | |
| S.T.A.L.K.E.R.: Call of Pripyat | PC | 1.6.02 | Collector's Edition | | | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | Original | | 1526317 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| Sports Car GT | PC | 1.52US | CD-ROM Classics | | 1187207 | |
| SpellForce | PC | 1.52.64763 | Platinum Edition | | 11121-1DDA | |
| The Sims 2: Glamour Life Stuff | PC | 1.5.0.121 | Original | | 1520807 | |
| Supreme Commander: Forged Alliance | PC | 1.5.0.1 | Original, Gold Edition | | 111603 | |
| The Sims 3 | PC | 1.42.130.019037 | The Sims 3 Starter Pack | | 1539003301 | |
| SWAT 3: Close Quarters Battle | PC | 1.4 | Elite Edition | | | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, 636130 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition | | Part # 24356CD1 | |
| Surfing H3O Surfing H³O | PS2 | 1.20 | Original | | SLUS 20092 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.377 | Rerelease | | 1497037 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.377 | Rerelease | | 1497027 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.312 | Original | | 1497017 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.312 | Original | | 1497007 | |
| Silent Hunter: Wolves of the Pacific | PC | 1.2.0.0 | Original | | 683438-DVD1 | |
| Star Wars: Battlefront | PC | 1.2 | Rerelease | | 3248130, 3248130R | |
| Star Trek: Armada | PC | 1.2 | Rerelease, Star Trek: Action Pack | | 1000913.101.US, 32257.102.US | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Special Edition | | 04-12884CD | |
| The Sims 2: Apartment Life (Expansion Pack) | PC | 1.16.0.179 | Original, Slim Case | | 1907807 | |
| System Shock 2 | PC | 1.15 | Original | | 796907 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original, Slim Case | | 1536717 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 1) | PC | 1.10.0.111 | Original, Slim Case | | 1536707 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 1.10 | Original | | | |
| Star Trek: Voyager: Elite Force | PC | 1.10 | Rerelease | | 1000912.101.US, 32097.101.US | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | Original | | 1474007 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| SimCity Classic | PC | 1.1 (Windows), 1.4 (Mac) | Scholastic | | 0002-000-0612-A | |
| SuperPower | PC | 1.1 | Original | | | |
| Su-27 Flanker | PC | 1.1 | Rerelease | | 2212510 | |
| Stronghold FireFly Studios' Stronghold | PC | 1.1 | Original | | | |
| Strife | PC | 1.1 | Original | | | |
| Star Wars: Battlefront II | PC | 1.1 | Rerelease (DVD-ROM) | | 3288130, 3288130R | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.1 | Original, Expansion Collection Volume Two, Mega Deluxe | | 1439827 | |
| SimPark | PC | 1.1 | Rerelease, Scholastic | | 1126207, 5710372C SP1 | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.1 | Shareware | | 04-12264CD | |
| Saints of Virtue | PC | 1.1 | Original | | | |
| StarCraft Shareware | PC | 1.0s | Original | | | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0A | Collector Series, Rerelease | | 2064130, 8051832 | |
| Soldier of Fortune | PC | 1.07f | Platinum Edition (Rerelease) | | 31761.101.US | |
| Sid Meier's Civilization III | PC | 1.07f | Small Box Release | | BIPCIV3CDRV1 | |
| StarCraft | PC | 1.05b | StarCraft Battle Chest | | S0437070 | |
| Stonekeep | PC | 1.05 | Original | | CD-ICD-045-0 | |
| Stonekeep | PC | 1.05 | Original | | CD-ICD-045-0 | |
| StarCraft: Brood War (Expansion Set) | PC | 1.05 | StarCraft Battle Chest | | S02416, S0241621 | |
| StarCraft | PC | 1.05 | StarCraft Battle Chest | | S7154921 | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
| Soldier of Fortune | PC | 1.03 | Special Tactical Edition | | 1001348.101.US | |
| Soldier of Fortune | PC | 1.03 | Original | | 1000910.101.US | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.US | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.02a | Original | | 9541830 | |
| Star Trek: Starfleet Command | PC | 1.02.01 | Gold Edition | | CD-W58-1177-0 | |
| SimCopter SimCopter: Fly Missions in the Metropolis | PC | 1.02 | CD-ROM Classics, 10 Sims for $20 | | 1119307, 1119317, 1641567 | |
| Shivers | PC | 1.02 | Rerelease | | | |
| Sid Meier's Civilization III: Play the World | PC | 1.01f | Original | | Part # 24115CD | |
| Star Wars: Rebel Assault | MAC | 1.01 | Original | | 634630 | |
| SiN | PC | 1.01 | Rerelease | | 6236 01 | |
| Sid Meier's SimGolf | PC | 1.01 | Rerelease | | 1434917 | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Star Wars: Empire at War: Forces of Corruption (Disc 2) | PC | 1.00.55911 | Original | | 7131831 | |
| Star Wars: Empire at War: Forces of Corruption (Disc 1) | PC | 1.00.55911 | Original | | 7131830 | |
| Starship Titanic (Disc 1) Douglas Adams: Starship Titanic | PC | 1.00.42b | Rerelease | | | |
| Star Wars: Empire at War (Disc 2) | PC | 1.00.36493 | Original, Collector's Edition | | 8541831 | |
| Star Wars: Empire at War (Disc 2) | PC | 1.00.36493 | Rerelease | | 8541831R | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Original, Collector's Edition | | 8541830 | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Rerelease | | 8541830R | |
| Street Fighter IV | PC | 1.00.3013 | Original, Limited Edition | | | |
| Silent Hunter II Silent Hunter II: WWII U-Boat Combat Simulator | PC | 1.00.06 | Original | | 610465-CD | |
| Spore | PC | 1.00.000 | Original | | 1535207 | |
| Startopia | PC | 1.00 | Original | | MSTARPUS01 | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 1.00 | Bundle Version Logitech OEM | | 601479-0100 | |
| Star Trek: Deep Space Nine: Dominion Wars | PC | 1.00 | Original | | | |
| The Software Toolworks' Star Wars Chess | PC | 1.00 | Bundle Version OEM | | 13-004-060 | |
| Sins of a Solar Empire | PC | 1.00 | Original | | | |
| SimTown | PC | 1.00 | Rerelease | | 1126107 | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | 1.00 | Original | | 1430717 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| ShellShock: Nam '67 | PC | 1.00 | Original | | MSHOCPUS01 | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| The Sims 3 | PC | 1.0.631.00001, 0.0.0.11195 | Original, The Sims 3: Deluxe | | 1539007 | |
| SimCity 3000 | PC | 1.0.557.0 | Original | | 1500107 | |
| Supreme Commander | PC | 1.0.3189 | Original, Gold Edition | | part # 109050 | |
| Silent Heroes: Elite Troops of WWII | PC | 1.0.29.0 | Original | | | |
| The Sims Life Stories | PC | 1.0.22.17622 | Original | | 1528207 | |
| The Sum of All Fears | PC | 1.0.12.0 | Original | | 650362-CD | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 2) | PC | 1.0.1 | Rerelease | | 9551831R, 9551831R1 | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | PC | 1.0.1 | Rerelease | | 9551830R1 | |
| The Sims 2 (Game Disk) | PC | 1.0.0.932 | Special DVD Edition | | 1488307 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Original | | | |
| The Sims 2 (Disc 4) | PC | 1.0.0.1022 | Rerelease | | 1472616, 1472656, 1472696, 1527637 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.1022 | Rerelease | | 1472606, 1472646, 1472686, 1527627 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.1022 | Rerelease | | 1472636, 1472676, 1472697, 1527617 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1022 | Rerelease | | 1472626, 1472666, 1472687 | |
| Strike Fighters: Project 1 | PC | 1.0.0.1 | Original | | 24147CD | |
| Steel Tide | PC | 1.0.0.1 | Original | | | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD2 | |
| Sid Meier's Pirates! (Disc 1) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD1 | |
| Star Wars: Knights of the Old Republic (Disc 4) | PC | 1.0.0.0 | Original | | 3191833 | |
| Star Wars: Knights of the Old Republic (Disc 3) | PC | 1.0.0.0 | Original | | 3191832 | |
| Star Wars: Knights of the Old Republic (Disc 2) | PC | 1.0.0.0 | Original | | 3191831 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.0.0.0 | Original | | 3191830 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Slob Zone 3D H.U.R.L. | PC | 1.0 SE | Special Edition | | SLZ344AE-CD | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Original | | 635930 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Original | | 633830 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Rerelease, LucasArts Archives Vol. IV, The: Star Wars Collection II | | 3064130, 8061835 | |
| Syberia II (Disc 2) B. Sokal Syberia II | PC | 1.0 | Original, Viva Media Adventure Anthology | | 71702321 | |
| Syberia II (Disc 1) | PC | 1.0 | Original | | 71702221 | |
| Syberia (Disc 2) | PC | 1.0 | Original | | | |
| Syberia (Disc 1) | PC | 1.0 | Original | | | |
| SWAT 3: Close Quarters Battle | PC | 1.0 | Original | | | |
| Super Street Fighter II Turbo | PC | 1.0 | Original | | | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 3) | PC | 1.0 | Original | | 11001-3CDA | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 2) | PC | 1.0 | Original | | 11001-2CDA | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 1) | PC | 1.0 | Original | | 11001-1CDA | |
| Stronghold Crusader FireFly Studios' Stronghold Crusader | PC | 1.0 | Original | | | |
| Streets of SimCity | PC | 1.0 | CD-ROM Classics, 10 Sims for $20 | | 1127517 | |
| Still Life (Disc 2) (Play) | PC | 1.0 | Original | | PCO461CD | |
| Still Life (Disc 1) (Install) | PC | 1.0 | Original | | PCO461CD | |
| Starsiege: Tribes | PC | 1.0 | Original | | | |
| Starsiege (Disc 2) | PC | 1.0 | Original | | | |
| Starsiege (Disc 1) | PC | 1.0 | Original | | | |
| Star Wars: Yoda Stories | PC | 1.0 | Original | | 3111830 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051831 | |
| Star Wars: X-Wing Alliance (Disc 2) | PC | 1.0 | Original | | 2091831 | |
| Star Wars: X-Wing Alliance (Disc 1) | PC | 1.0 | Original | | 2091830 | |
| Star Wars: The Force Unleashed II | PC | 1.0 | Original | | 3411830 | |
| Star Wars: The Clone Wars: Republic Heroes | PC | 1.0 | Original | | 3381830 | |
| Star Wars: Starfighter | PC | 1.0 | Original, Rerelease | | 6551830, 6551830R1 | |
| Star Wars: Shadows of the Empire: Battle of Hoth | PC | 1.0 | Bundle Version Diamond OEM | | 75000204-100 | |
| Star Wars: Shadows of the Empire | PC | 1.0 | Original | | 3121830 | |
| Star Wars: Rebellion | PC | 1.0 | Original | | 8511830 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | 1.0 | Original | | 3091831, CDRM1361640 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PC | 1.0 | Original | | 3091830, CDRM1361630 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 4) | PC | 1.0 | Original | | 3261833, 3261833R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 3) | PC | 1.0 | Original | | 3261832, 3261832R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 2) | PC | 1.0 | Original | | 3261831, 3261831R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Rerelease | | 3261830R | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Original | | 7101830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | 1.0 | Original | | 9521831 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | 1.0 | Original | | 9521830 | |
| Star Wars: Jar Jar's Journey Adventure Book | PC | 1.0 | Original | | #3520530 | |
| Star Wars: Galactic Battlegrounds: Clone Campaigns | PC | 1.0 | Original | | 7111830 | |
| Star Wars: Galactic Battlegrounds (Disc 2) (Play) | PC | 1.0 | Original | | 8531831, 8531831R1 | |
| Star Wars: Galactic Battlegrounds (Disc 1) (Install) | PC | 1.0 | Original | | 8531830, 8531830R1 | |
| Star Wars: Episode I: The Gungan Frontier | PC | 1.0 | Original | | #3512030 | |
| Star Wars: DroidWorks | PC | 1.0 | Original | | | |
| Star Wars: Battlefront (Disc 3) | PC | 1.0 | Original | | 3241832 | |
| Star Wars: Battlefront (Disc 2) | PC | 1.0 | Original | | 3241831 | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3241830 | |
| Star Wars: Battle for Naboo | PC | 1.0 | Original | | 6561830, 6561830R1 | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.0 | Original | | | |
| Star Trek: Starfleet Command III | PC | 1.0 | Original | | 32255.101.US | |
| Star Trek: New Worlds | PC | 1.0 | Original | | | |
| Star Trek: Klingon Academy | PC | 1.0 | Interactive Demo | | CD-C95-856-D1 | |
| Star Trek: Deep Space Nine: The Fallen | PC | 1.0 | Original | | 0-671-57663-1, S5293110 | |
| Star Trek: Bridge Commander | PC | 1.0 | Original | | 31127.101.US | |
| Star Command Revolution | PC | 1.0 | Original | | 04-12257CD | |
| Sportsman's Paradise II | PC | 1.0 | Original | | P/N 4-19599CDSL | |
| Special Forces: Nemesis Strike (Disc 3) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Spec Ops: Ranger Gold | PC | 1.0 | Original, Platinum Collection | | CD-RG-004 | |
| Spec Ops: Platinum Collection (Disc 2) | PC | 1.0 | Original | | | |
| Space Siege | PC | 1.0 | Original | | | |
| Sonic & Knuckles Collection | PC | 1.0 | Expert Software, Sonic Action 4 Pack | | 6820 01, T-6820-02 | |
| Solitaire Antics | PC | 1.0 | Original | | | |
| Smart Games Puzzle Challenge 3 | PC | 1.0 | Original | | 99254 | |
| Singularity | PC | 1.0 | Original | | 33309101US | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459507 | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462617 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462607 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1472007 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: House Party (Expansion Pack) | PC | 1.0 | Original | | 1431307, 1431317 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457657 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457647 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims Online (Disc 2) | PC | 1.0 | Original | | 1436717 | |
| The Sims Online (Disc 1) | PC | 1.0 | Original | | 1436707 | |
| The Sims 2 (Disc 4) | PC | 1.0 | Original | | 1472637 | |
| The Sims 2 (Disc 3) | PC | 1.0 | Original | | 1472627 | |
| The Sims 2 (Disc 2) | PC | 1.0 | Original | | 1472617 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| SimGolf | PC | 1.0 | Original | | 0093-000-0601-A | |
| SimCity Enhanced CD-ROM | PC | 1.0 | Rerelease | | CD-ICD-508-0 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | 1457317 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | 1457307 | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity | PC | 1.0 | Original, Limited Edition | | 1971403401 | |
| Silent Hunter III | PC | 1.0 | Original | | 681953-DVD | |
| Sierra Pro Pilot 98 | PC | 1.0 | Original | | | |
| Sid Meier's Civilization II | PC | 1.0 | Original | | 0-492-47-101 | |
| Shrak Shrak for Quake | PC | 1.0 | Original | | | |
| ShellShock 2: Blood Trails | PC | 1.0 | Original | | 5000026211 | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| Shadowbane | PC | 1.0 | Original | | 650478-CD | |
| Shadow Watch | PC | 1.0 | Original | | | |
| Sentinel Returns | PC | 1.0 | Original | | CDAC-148200 | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| The Saboteur | PC | 1.0 | Original | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0 | Original | | 109310 | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD950001D | |
| Star Trek: Starfleet Academy (Disc 5) | PC | 0.99, 1.1 | Original | | CD-H95-069-4, CD-MCR-069-4 | |
| Star Trek: Starfleet Academy (Disc 4) | PC | 0.99, 1.1 | Original | | CD-H95-069-3, CD-MCR-069-3 | |
| Star Trek: Starfleet Academy (Disc 3) | PC | 0.99, 1.1 | Original | | CD-H95-069-2, CD-MCR-069-2 | |
| Star Trek: Starfleet Academy (Disc 2) | PC | 0.99, 1.1 | Original | | CD-H95-069-1, CD-MCR-069-1 | |
| Star Trek: Starfleet Academy: Cadet Briefing | PC | 0.99 | Star Trek: Federation Compilation | | CD-C95-893-0 | |
| Star Trek: Starfleet Academy (Disc 1) | PC | 0.99 | Original | | CD-H95-069-0 | |
| The Sims 3: Late Night (Expansion Pack) | PC | 0.2.0.125 | Original, The Sims 3 Starter Pack | | 1915003301 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | PC | 0.0.0.0 | Original | | 12241-1DDA2 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | PC | 0.0.0.0 | Original | | 12241-1DDA | |
| Syndicate Plus | PC | | CD-ROM Classics: Gold Edition | | 5737 | |
| Syndicate | PC | | Original | | 1922907 | |
| Supreme Commander (Bonus Disc) | PC | | Original | | | |
| SuperKarts | PC | | Original | | 04-10242CD | |
| Superdead | PC | | Original | | | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | CD-ROM Classics | | 1215007 | |
| Super Scattergories | PC | | General Mills | | A50040 | |
| Super Scattergories | PC | | Scholastic | | | |
| Super 3D Noah's Ark | PC | | Original | | | |
| Sub Command (Disc 2) Sub Command: Akula Seawolf 688(I) | PC | | Naval Combat Pack | | 903366CD4 | |
| Sub Command (Disc 1) Sub Command: Akula Seawolf 688(I) | PC | | Naval Combat Pack | | 903366CD3 | |
| Strike Commander | PC | | CD-ROM Classics | | | |
| Strike Commander | PC | | Original | | RVL 13-004-0046 | |
| Streets of SimCity | PC | | Ultimate Sim Series | | 10402 | |
| Strawberry Shortcake: Amazing Cookie Party | PC | | Scholastic | | P/N CDR9663741 | |
| Stratego | PC | | Original | | 99032 | |
| Stolen (Disc 2) Stolen: Infiltrate · Steal · Vanish | PC | | Original | | | |
| Stolen (Disc 1) (Game Disc) Stolen: Infiltrate · Steal · Vanish | PC | | Original | | | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67023 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67021 | |
| Star Wars: Yoda's Challenge | PC | | Original | | 3520030 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Original | | 635930 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Rerelease | | 2054130 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | Original | | 2061830 | |
| Star Wars: Screen Entertainment | PC | | Original, The LucasArts Archives Vol. I | | 633630 | |
| Star Wars: Republic Commando (Disc 2) | PC | | Original | | 3251831 | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) | PC | | Original | | 3251830 | |
| Star Wars: Republic Commando | PC | | Original | | 3258130, 3258130R | |
| Star Wars: Pit Droids | PC | | Original | | 3513030 | |
| Star Wars: Millennium Falcon CD-ROM Playset | PC | | Original | | | |
| Star Wars: Math: Jabba's Game Galaxy | PC | | Original, Scholastic | | P/N CDR5077850 | |
| Star Wars: Jedi Knight: Dark Forces II: Pathways to the Force | PC | | Bundle Version Diamond OEM | | 646230, 75000202-100, CD-C95-829-DIA | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | LucasArts Archive Series | | | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | LucasArts Archive Series | | | |
| Star Wars: Galactic Battlegrounds Saga (Disc 2) | PC | | Rerelease | | 8531031R, 8531031R1 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 1) | PC | | Rerelease | | 8531030R, 8531030R1 | |
| Star Wars: Attacktix: Battle Figure Game | PC | | Starter Set CD-ROM | | | |
| Star Wars: Attacktix: Battle Figure Game | PC | | Starter Set CD-ROM Series 2 | | | |
| Star Wars: Anakin's Speedway | PC | | Original | | #3518030 | |
| Star Trek: Starship Creator (Add-On Pack) | PC | | Deluxe | | 0-671-31758-X | |
| Star Trek: Starship Creator | PC | | Original, Deluxe | | 31509-9 | |
| Star Trek: Klingon Academy (Disc 6) | PC | | Original | | CD-C95-856-5 | |
| Star Trek: Klingon Academy (Disc 5) | PC | | Original | | CD-C95-856-4 | |
| Star Trek: Klingon Academy (Disc 4) | PC | | Original | | CD-C95-856-3 | |
| Star Trek: Klingon Academy (Disc 3) | PC | | Original | | CD-C95-856-2 | |
| Star Trek: Klingon Academy (Disc 2) | PC | | Original | | CD-C95-856-1 | |
| Star Trek: Klingon Academy (Disc 1) | PC | | Original | | CD-C95-856-0 | |
| Star Trek: Klingon (Disc 2) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon (Disc 1) (Installation) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Judgment Rites | PC | | Star Trek: Federation Compilation | | CD-C95-893-1 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Star Trek: Federation Compilation | | CD-C95-893-2 | |
| Star Defender III | PC | | Original | | CD001697 | |
| SSN-21 Seawolf | PC | | CD-ROM Classics: Gold Edition | | 5735 | |
| Spore: Creepy & Cute Parts Pack | PC | | Original | | 1907607 | |
| Spore: Creature Creator | PC | | Original | | 1586407 | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Spear of Destiny: Super CD Pack | PC | | Super CD Pack | | | |
| Space Bucks | PC | | Original | | | |
| South Park | PC | | Original | | | |
| Sorry! | PC | | Original | | 99040 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Sonic R | PC | | Expert Software | | 682501.101.US | |
| Sonic R | PC | | Sonic Action 4 Pack, Twin Pack | | 682501.101.US | |
| Sonic CD | PC | | Expert Software | | 6805 02 | |
| Sonic 3D Blast | PC | | Expert Software | | 6822 01 | |
| Soldier of Fortune II: Double Helix (Disc 1) | PC | | Original | | 31147.101.US | |
| Soft Kill | PC | | Original | | | |
| So You Wanna Be a Redneck | PC | | Original | | | |
| Small Soldiers: Squad Commander | PC | | | | Product# 99264 | |
| Small Soldiers: Globaltech Design Lab | PC | | | | Product# 99144 | |
| Slots 100 | PC | | Cosmi | | CDR712D1, SJ 062001 | |
| Sin Episodes: Emergence SiN Episodes: Emergence | PC | | Original | | 984707 | |
| SimTheme Park Sim Theme Park | PC | | Scholastic | | 1403307 | |
| SimTheme Park (Bonus Rides and Attractions) Sim Theme Park | PC | | Gold Edition, Sim Mania 2 | | 1229817, 1403347, 1641527 | |
| SimTheme Park Sim Theme Park | PC | | Gold Edition | | 1403337 | |
| The Sims: Vacation (Expansion Pack) | PC | | Expansion Collection Volume Three | | 1448807 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Expansion Collection Volume Two | | 1472017 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Original | | 1472017 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | | Expansion Collection Volume Two | | 1472007 | |
| The Sims: House Party (Expansion Pack) | PC | | Double Deluxe, Expansion Collection Volume One, Mega Deluxe | | 1446107 | |
| The Sims: Double Deluxe (Bonus CD) | PC | | Double Deluxe, Mega Deluxe | | 1474107 | |
| The Sims 3: Seasons (Expansion Pack) | PC | | Original, Limited Edition | | 1978303301 | |
| The Sims 3: Pets (Expansion Pack) | PC | | Original, Limited Edition | | 1962207 | |
| The Sims 3: Hidden Springs | PC | | Original, The Sims 3: Worlds Bundle | | 1979707 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Family Fun Stuff | PC | | Original | | 1515807 | |
| The Sims 2 (Bonus Disk) | PC | | Special DVD Edition | | 1488317 | |
| SimLife SimLife: The Genetic Playground | PC | | Scholastic | | 1111707, 7845126C SP1 | |
| SimFarm SimFarm: SimCity's Country Cousin | PC | | Rerelease, 10 Sims for $20 | | 11116, 1162207 | |
| SimEarth | PC | | Scholastic | | 5675434C, DP19 | |
| SimCoaster | PC | | Original | | 1425707 | |
| SimCity Classic | PC | | Collector's Series | | 0002-000-0612-A | |
| SimCity 3000 | PC | | Scholastic | | 1500107 | |
| SimCity 2000 Special Edition | PC | | CD-ROM Classics, Scholastic | | 10365, 1131107, 5710243CSP1, DP10 | |
| Sid Meier's Civilization V | PC | | Original, Special Edition | | 31817-1 | |
| Sid Meier's Civilization III (Bonus CD) | PC | | Game of the Year Edition | | Part # 24356CD2 | |
| Shrine Circus Tycoon | PC | | | | 31933.101.US | |
| Shift 2: Unleashed | PC | | Limited Edition | | 1948307 | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the fun of it | | EOA844AE-CD, KES005 | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Sega Smash Pack 2 | PC | | Original, Sonic Action 4 Pack | | 30107.101.US | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screamer | PC | | White Label | | | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scorched Planet | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sam & Max Hit the Road | PC | | Rerelease, The LucasArts Archives Vol. I | | 634430 | |
| Saints Row: The Third (Disc 2) | PC | | Original | | | |
| Saints Row: The Third (Disc 1) | PC | | Original | | | |
| Sacred 2 (Disc 2) | PC | | Original | | | |
| Sacred 2 (Disc 1) | PC | | Original | | | |
| S.C.A.R.S. | PC | | Original | | | |
| S!Zone for SimCity 2000 | PC | | Original | | | |