Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sam & Max Hit the Road | PC | | Original | | 634031 | |
| Sanitarium | PC | | Demo | | | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
| Shadoan | PC | | Interactive Preview | | | |
| Shakii the Wolf | PC | | Original | | | |
| Shamrock Spring '97 Shamrock Spring '97 Demo Disk | PC | | | | | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shivers | PC | | Demo | | | |
| Sierra Holiday Software Sampler | PC | | | | | |
| Sierra Products Demo America Online featuring Sierra Online | PC | | | | R00482 | |
| Sierra Super Sampler Sierra On-Line Demos | PC | | | | | |
| SimCity 2000 Special Edition | PC | | Original | | 0126-000-0601-A | |
| SimCity 2000 Special Edition | PC | | CD-ROM Classics, Scholastic | | 10365, 1131107, 5710243CSP1, DP10 | |
| SimCity 3000 | PC | | Domino's Pizza / Easter Seals | | | |
| SimCoaster: Bonus Disk SimCoaster Extra Value Pack | PC | | | | 4002307 | |
| The Sims Online: Sampler Disc | PC | | Original | | 4025407 | |
| Smashing Reversi Reversi | PC | | Pocketware | | #11 | |
| Sonic CD | PC | | Expert Software | | 6805 01 | |
| Sounds Best on Sound Blaster Every Game Sounds Best on Sound Blaster: 24-bit Advanced HD | PC | | | | | |
| Space Colony | PC | | Interactive Demo | | | |
| Space Dudes | PC | | Original | | | |
| Spartan: Total Warrior | XBOX | | Demo | | SE-138 | |
| Spec Ops: Rangers Lead the Way | PC | | Demo | | CD-RC008 | |
| Spell It Deluxe | PC | | Original | | | |
| Spider-Man 2 | PC | | Demo | | | |
| Spyro 2: Ripto's Rage! / Crash Team Racing | PSX | | Demo | | SCUS 94632 | |
| Square Enix E3 2005 Media CD | PC | | Press Kit | | | |
| Square Enix: Final Fantasy VII Advent Children Trailer | PC | | Press Kit | | | |
| Star Wars: Episode I: The Gungan Frontier | PC | | Demo | | #3519030 | |
| Star Wars: Jedi Knight: Dark Forces II: Pathways to the Force | PC | | Bundle Version Diamond OEM | | 646230, 75000202-100, CD-C95-829-DIA | |
| Star Wars: Rebel Assault | MAC | | Demo | | CDRM1209730 | |
| Star Wars: Screen Entertainment | PC | | Original, The LucasArts Archives Vol. I | | 633630 | |
| Star Wars: Shadows of the Empire: Battle of Hoth | PC | | Bundle Version Diamond OEM | | 75000204-100 | |
| Star Wars: Yoda's Challenge Activity Center | PC | | Demo | | #3529030 | |
| Stronghold Crusader | PC | | Interactive Demo | | | |
| Suncom Technologies Presents: 10 Hit Games by Apogee | PC | | Original | | 63-0647 | |
| Super Solitaire 15 | PALM | | Rerelease | | 332-0204-10 | |
| SWAT 4 | PC | | Demo | | | |
| Switchball | PC | | Original | | S7275110 | |
| Syphon Filter: Logan's Shadow | PSP | 0.10 | Test Sample | | UCUS-98606 | |
| S.L.A.I.: Steel Lancer Arena International S.L.A.I.: Phantom Crash | PS2 | 0.11 | Beta | | SLUS 29132 | |
| Schizm: Mysterious Journey | PC | 0.99 | Playable Demo | | | |
| Spider-Man: Web of Shadows 스파이더 맨: 웹 오브 쉐도우 | PS3 | 01.00 | Original | | BLKS 20086 … | |
| Singularity 싱귤래리티 | PS3 | 01.01 | Original | | BLKS 20172 … | |
| Spec Ops: The Line | PS3 | 01.01 | Original, Premium Edition | | BLKS 20358 … | |
| Spelvin Goolie Private Eyeball Spelvin Goolie Private Eyeball: The World's Greatest Left-Handed Detective | PC | 1.0 | Original | | ROW-10942 | |
| Star Trek: Klingon Academy | PC | 1.0 | Interactive Demo | | CD-C95-856-D1 | |
| Star Wars: Jedi Knight: Dark Forces II | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061832 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061833 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PC | 1.0 | Original | | 3091830, CDRM1361630 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | 1.0 | Original | | 3091831, CDRM1361640 | |
| Stonekeep | PC | 1.0 | Interactive Preview | | CD-ICD-190-0 | |
| Sampler Disc for PSP Vol. 1 | PSP | 1.00 | Demo | | UCJB-98301 | |
| Samurai Western | PS2 | 1.00 | Trade Demo | | SLUS-28051 | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.00 | Demo | | SLUS 29036 | |
| Secret Agent Clank | PSP | 1.00 | Demo | | UCUS 98707 | |
| Shadow Hearts | PS2 | 1.00 | Original | | SLUS 20347 | |
| Shadow Hearts: Covenant (Disc 1) | PS2 | 1.00 | Original | | SLUS 21041 | |
| Shadow Hearts: Covenant (Disc 2) | PS2 | 1.00 | Original | | SLUS 21044 | |
| Shadow of the Colossus | PS2 | 1.00 | Demo | | SCUS 97505 | |
| Shepherd's Crossing | PS2 | 1.00 | Original | | SLUS 21798 | |
| Shin Megami Tensei: Devil Summoner: Raidou Kuzunoha vs. the Soulless Army | PS2 | 1.00 | Trade Demo | | SLUS-28064 | |
| Shin Megami Tensei: Digital Devil Saga | PS2 | 1.00 | Trade Demo | | SLUS-28049 | |
| Shin Megami Tensei: Digital Devil Saga 2 | PS2 | 1.00 | Trade Demo | | SLUS-28052 | |
| Shin Megami Tensei: Nocturne | PS2 | 1.00 | Trade Demo | | SLUS-28045 | |
| Shin Megami Tensei: Persona 3 | PS2 | 1.00 | Trade Demo | | SLUS-28067 | |
| Shin Megami Tensei: Persona 3 | PS2 | 1.00 | Original | | SLUS 21569 | |
| Shin Megami Tensei: Persona 3 FES | PS2 | 1.00 | Trade Demo | | SLUS-28068 | |
| Shin Megami Tensei: Persona 3 Portable | PSP | 1.00 | Trade Demo | | ULUS-80022 | |
| Shin Megami Tensei: Persona 4 | PS2 | 1.00 | Trade Demo | | SLUS-28069 | |
| Shin Megami Tensei: Persona 4 | PS2 | 1.00 | Original | | SLUS 21782 … | |
| Shinobi | PS2 | 1.00 | Trade Demo | | SLUS-28016 | |
| SkyGunner | PS2 | 1.00 | Demo | | SLUS 29020 | |
| Sly 3: Honor Among Thieves | PS2 | 1.00 | Demo | | SCUS 97484 | |
| SOCOM 3: U.S. Navy SEALs | PS2 | 1.00 | Beta | | SCUS 97489 | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.00 | Beta | | SCUS 97366 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo | PSP | 1.00 | Demo | | UCUS 98638 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 2 | PSP | 1.00 | Demo | | UCUS 98691 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 2 | PSP | 1.00 | Demo | | UCUS 98677 | |
| SOCOM: U.S. Navy SEALs: Tactical Strike | PSP | 1.00 | Demo | | UCUS 98714 | |
| Sonic Riders | PS2 | 1.00 | Demo | | SLUS 29179 | |
| Soulcalibur II | PS2 | 1.00 | Original, Greatest Hits, Namco Classic Fighter Collection | | SLUS 20643 … | |
| SpyHunter | PS2 | 1.00 | Original, Greatest Hits | | SLUS 20056 … | |
| Square Enix Sampler Disc Volume One: Drakengard Playable Demo | PS2 | 1.00 | | | SLUS 29087 | |
| Square Enix Sampler Disc Volume Two: Front Mission 4 Playable Demo | PS2 | 1.00 | | | SLUS 29098 | |
| SSX | PS2 | 1.00 | Original | | SLUS 20095 | |
| Star Wars: Jedi Starfighter | PS2 | 1.00 | Trade Demo | | SLUS - 280 … | |
| State of Emergency 2 | PS2 | 1.00 | Trade Demo | | SLUS-28056 | |
| Steambot Chronicles | PS2 | 1.00 | Trade Demo | | SLUS-28061 | |
| Stella Deus: The Gate of Eternity | PS2 | 1.00 | Trade Demo | | SLUS-28050 | |
| Stella Deus: The Gate of Eternity | PS2 | 1.00 | Original | | SLUS 21132 | |
| Summoner (Disc 1) | PC | 1.00 | Original | | | |
| Summoner (Disc 2) | PC | 1.00 | Original | | | |
| Syphon Filter: Dark Mirror | PSP | 1.00 | Demo | | UCUS 98656 | |
| Syphon Filter: Logan's Shadow | PSP | 1.00 | Demo | | UCUS 98704 | |
| Star Wars: Empire at War | PC | 1.00.35517 | Demo | | 8330730 | |
| Sega Saturn Bootleg II: On the Road Sega Screams Volume 1 | SS | 1.002 | Not for Resale | | 81068, 81075 | |
| Shadow Hearts: From the New World | PS2 | 1.01 | Original | | SLUS 21326 | |
| Shin Megami Tensei: Nocturne | PS2 | 1.01 | Original | | SLUS 20911 | |
| Sphinx and the Shadow of Set Sphinx and the Cursed Mummy | PS2 | 1.01 | Demo | | SLUS 29057 | |
| Stretch Panic | PS2 | 1.01 | Original | | SLUS 20182 | |
| Samurai Shodown Anthology | PSP | 1.02 | Original | | ULUS 10401 … | |
| Savage Skies | PS2 | 1.02 | Original | | SLUS 20430 | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.02 | Original, Greatest Hits | | SCUS 97275 … | |
| Speed Busters | PC | 1.02 | Demo | | | |
| Stonekeep | PC | 1.1 | Interactive Preview | | | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Original | | GAG744AE-CD | |
| Super Solvers: Midnight Rescue! | PC | 1.1 | Rerelease | | CSM744AE-CD | |
| Super Solvers: OutNumbered! | PC | 1.1 | Rerelease | | CSO744AE-CD | |
| Sky Odyssey | PS2 | 1.10 | Original | | SLUS 20134 | |
| Super Solvers: Spellbound! | PC | 1.12 | Rerelease | | SBO744CE-CD | |
| Silent Steel | PC | 1.24.18.121 | Bundle Version Packard Bell OEM: Demo | | 170308 | |
| Stronghold FireFly Studios' Stronghold | PC | 1.3 | Interactive Demo | | | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, 636130 | |
| Star Trek: Deep Space Nine: The Fallen | PC | 11-2000-a | Demo | | | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 2.0 | Bundle Version Diamond OEM | | 75000203-100 | |
| Sword of the New World: Granado Espada | PC | 2.1.18 | | | | |
| Star Wars: Making Magic | PC | QA1.03 | Original, LucasArts Archives Vol. II, The: Star Wars Collection | | 8031835 | |
| Spider-Man | XBOX | Rev 1 | Platinum Hits | | AV-006 | |
| Syberia | PC | SSV1.0 | Demo | | DEM379CD | |