Region | Title | System | Version | Edition | Languages | Serial | Status |
| Syndicate Plus | PC | | | | | |
| Sword of the New World: Granado Espada | PC | 2.1.18 | | | | |
| SuperPower | PC | 1.0 | | | PC35320JC | |
| Super Stories: My Favorite Things | CDI | | | | | |
| Super Stories: Mom is Going to Stop It | CDI | | | | | |
| Super Bender Boot Disc | PS2 | 2.00 | | | | |
| Sundance Channel: Sept. 2000 | PHOTO-CD | | | | | |
| Streets of SimCity | PC | | | | | |
| Stowaway DK Multimedia: Stephen Biesty's Incredible Cross-Section: Stowaway | PC | | | | | |
| Steven Spielberg's Director's Chair (Disc 3) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD300CD | |
| Steven Spielberg's Director's Chair (Disc 2) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD200CD | |
| Steven Spielberg's Director's Chair (Disc 1) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD100CD | |
| Stellar 7 | PC | | | | | |
| Starbright Asthma CD-ROM Game: Quest for the Code | PC | | | | | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, CDRM1221330 | |
| Star Wars: Rebel Assault: Special Edition | PC | | | | 636130 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | | | 7101830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | 1.0 | | | 9521831 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | 1.0 | | | 9521830 | |
| Star Trek: Secret of Vulcan Fury (Non-Interactive Preview) | PC | | | | CD-C95-647-N1 | |
| Star Trek: Secret of Vulcan Fury (Non-Interactive Trailer) | PC | | | | CD-C95-647-N2 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | | | CD-ICD-016-4 | |
| Star Fighter | MAC | | | | 03239-001 | |
| Square Enix Sampler Disc Volume One: Drakengard Playable Demo | PS2 | 1.00 | | | SLUS 29087 | |
| Sports: Football | CD32 | | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Snowboard Park Tycoon | PC | | | | 30983.101.US | |
| Small Soldiers: Squad Commander | PC | | | | Product# 99264 | |
| Small Soldiers: Globaltech Design Lab | PC | | | | Product# 99144 | |
| SkyTrip America SkyTrip America: An Incredible Ride Through U.S. History! | PC | 1.0 | | | | |
| Ski Park Manager 2003: Gold Edition Val d'Isère Ski Park Manager 2003: Gold Edition | PC | | | | 71102221 | |
| Sitting Ducks | PC | 1.0 | | | | |
| Sins of a Solar Empire: Trinity | PC | | | | | |
| Sing-Along Kids: Vol. 2 | PC | | | | | |
| The Sims | MAC | | | | | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | | | 1491707 | |
| Silverload | PC | | | | | |
| Silver (Disc 2) | PC | 1.08C | | | | |
| Silver (Disc 1) | PC | 1.08C | | | | |
| Sierra's School House: English (Disc 2) | PC | | | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Shrine Circus Tycoon | PC | | | | 31933.101.US | |
| Shrek 2 | PC | | | | 32585.101.US | |
| Shorelines | CDI | | | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.00 | | | | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| Sherlock Holmes: Consulting Detective: Vol. III | MAC | 3.0 | | | CDRM 835400 | |
| Shattered Suns | PC | 1.0 | | | Part # CCS00003-1 | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Senha N. 1 | PC | | | | | |
| Self Selling Disc | CDI | 3.1 | | | 310-690-049-2 | |
| Self Selling Disc | CDI | 3.1 | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| The Scroll | PC | | | | | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Savage: The Ultimate Quest for Survival | PC | 1.0 | | | | |
| The Sacred Mirror of Kofūn (Disc 3) | PC | | | | CKOF1096-3A | |
| The Sacred Mirror of Kofūn (Disc 2) | PC | | | | CKOF1096-2A | |
| The Sacred Mirror of Kofūn (Disc 1) (Installation) | PC | | | | CKOF1096-1A | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 5.1 | 5 ft. 10 PAK Vol. 2 | | CD 7012 SPI | |
| Steel Panthers | PC | 1.1 | Awesome 4 Pak | | | |
| Shenmue III | PC | | Backer Exclusive Edition | | | |
| Syphon Filter: The Omega Strain | PS2 | 1.02 | Beta | | SCUS 97397 | |
| Stuart Little 2 | PSX | | Beta | | SCUS-94669 | |
| Street Fighter Alpha: Warriors' Dreams | SS | 1.000 | Beta | | | |
| Streak Hoverboard Racing | PSX | | Beta | | | |
| Star Wars: Battlefront II | PS2 | 1.01 | Beta | | SLUS-29164 | |
| Star Wars: Battlefront II | PS2 | 1.01 | Beta | | SLUS-21240 | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| SSX Blur | WII | | Beta | | | |
| Spyborgs | WII | | Beta | | | |
| SPRay | WII | | Beta | | | |
| Sonic Mega Collection Plus | PS2 | 0.80 | Beta | | | |
| Sonic CD | MCD | 1.15 | Beta | | | |
| Ski-Doo Snowmobile Challenge | WII | | Beta | | | |
| Skate It | WII | | Beta | | | |
| The Sims 3 | WII | | Beta | | | |
| The Sims 2 | PS2 | 1.00 | Beta | | SLUS-21066 | |
| The Sims 2 | PS2 | 1.00 | Beta | | SLUS-21265 | |
| The Simpsons: Road Rage | PS2 | 1.00 | Beta | | SLUS-20305 | |
| Silent Hill 2 | PS2 | 1.20 | Beta | | | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Beta | | | |
| Shiren the Wanderer | WII | | Beta | | | |
| Shining Wisdom | SS | 1.000 | Beta | | | |
| Shining Force III | SS | 1.000 | Beta | | | |
| Shaun White Snowboarding: Road Trip | WII | | Beta | | | |
| Secret Agent Clank | PSP | .01 | Beta | | UCUS-98697 | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| Samurai Warriors: Katana | WII | | Beta | | | |
| Sam & Max: Season One | WII | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| Shanghai: Great Moments | PC | 2.00 | Bundle Version Canon OEM | | | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| SSN-21 Seawolf Sea Wolf | PC | | Bundle Version Creative Labs OEM | | | |
| Shogo: Mobile Armor Division | PC | 2.2 | Bundle Version Creative Labs OEM | | 1713310341 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sacrifice | PC | | Bundle Version Hewlett Packard OEM | | CD-C951041-PC2E | |
| Strategy Games of the World | PC | 1.2 | Bundle Version IBM OEM | | P/N 75H9348 | |
| Star Trek: Voyager: Elite Force | PC | 0.28 | Bundle Version Linksys OEM | | 1000912.101.US | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 1.00 | Bundle Version Logitech OEM | | 601479-0100 | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Syndicate Plus | PC | | Bundle Version OEM | | | |
| Star Wars: X-Wing Alliance: Imperial Entanglements | PC | 1.0 | Bundle Version OEM | | 2091831, CD-C951918-VOE | |
| Star Wars: Starfighter | PC | 1.0 | Bundle Version OEM | | CD-W582934-PNE | |
| Star Wars: Episode I: The Phantom Menace: Naboo Missions | PC | 1.0 | Bundle Version OEM | | 3151830, CD-W581950-MLE | |
| Star Crusader | PC | 1.1 | Bundle Version OEM | | 0061-0085-01 | |
| Star Crusader | PC | 1.0n | Bundle Version OEM | | 0061-0085-00 | |
| Sports Car GT | PC | 1.52m | Bundle Version OEM | | | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | PC | Rev A | Bundle Version OEM | | RVL 13-004-073 | |
| The Software Toolworks' Star Wars Chess | PC | 1.00 | Bundle Version OEM | | 13-004-060 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| The Software Toolworks CD Deluxe Pack: Version 2 | PC | | Bundle Version Packard Bell OEM | | 2192611-590001 170122 | |
| San Francisco Rush The Rock: Alcatraz Edition | PC | | Bundle Version Quantum3D OEM | | 740-0033-01 #QM049 | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| Sonic CD | MCD | | Bundled with Sega CD | | 4407 | |
| Sol-Feace | MCD | RE | Bundled with Sega CD | | 4130 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Strike Commander | PC | | CD-ROM Classics | | | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| SSN-21 Seawolf | PC | | CD-ROM Classics: Gold Edition | | 5735 | |
| The Sims Online (Disc 2) | PC | 1.0 | Charter Edition | | 1461527 | |
| The Sims Online (Disc 1) | PC | 1.0 | Charter Edition | | 1461517 | |
| Strange Adventures in Infinite Space | PC | | Cheapass Games | | | |
| Surface: Mystery of Another World | PC | | Collector's Edition | | 33418010US | |
| Spider-Man 3 | PS3 | 01.00 | Collector's Edition | | BLUS-30030 | |
| Swift Classics Card Games for Windows | PC | | Cosmi | | CDR 720 OD1, SJ 041001 G | |
| Super Huey III | PC | | Cosmi | | CDR 707 D1, SJ 111000 | |
| SuperBike Racing SuperMoto Racing | PC | | Covermount | | | |
| Switchball | PC | 1.0 | Demo | | V536 15G091171100 | |
| Super Magnetic Neo | DC | 1.001 | Demo | | T-40206ND | |
| Summoner 2 | PS2 | 1.00 | Demo | | SLUS 29029 | |
| Stronghold FireFly Studios' Stronghold | PC | 1.3 | Demo | | | |
| Stratosphere: Conquest of the Skies | PC | | Demo | | | |
| Star Trek: New Worlds | PC | | Demo | | CD-C95-1097-D | |
| Star Trek: Klingon Academy | PC | 1.0 | Demo | | | |
| Star Trek: Deep Space Nine: The Fallen (Demo and Trailer) | PC | 11-2000-a | Demo | | | |
| Spy Fox in "Dry Cereal" | PC | | Demo | | | |
| Splashdown: Rides Gone Wild | PS2 | 1.00 | Demo | | SLUS 29054 | |
| Spider-Man | PC | | Demo | | | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| Space Ace | MCD | | Demo | | | |
| Soulcalibur II | PS2 | 1.00 | Demo | | SLUS 29058 | |
| Soulcalibur II | XBOX | | Demo | | NM-003 | |
| SOCOM: U.S. Navy SEALs: Combined Assault | PS2 | 1.00 | Demo | | SCUS 97560 | |
| SOCOM: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97205 | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97368 | |
| Sly Cooper and the Thievius Raccoonus | PS2 | 1.00 | Demo | | SCUS 97210 | |
| SkyGunner | PS2 | 1.00 | Demo | | SLUS 29020 | |
| Sierra's Sneak Peeks 2 | PC | | Demo | | | |
| ShowMaster | CDI | 1.0 | Demo | | | |
| Shonen Jump's One Piece: Grand Battle | PS2 | 1.00 | Demo | | SLUS 29159 | |
| Shivers Two: Harvest of Souls | PC | 1.0 | Demo | | | |
| Shamrock Spring '97 | PC | | Demo | | | |
| Shadow Ops: Red Mercury | XBOX | | Demo | | IG-037 | |
| Shadow of Rome | PS2 | 1.00 | Demo | | SLUS 29139 | |
| Shadow Man | PC | | Demo | | | |
| Schizm: Mysterious Journey (Playable Demo) | PC | 0.99 | Demo | | | |
| Sanitarium | PC | | Demo | | | |
| San Francisco Rush 2049 | DC | 1.000 | Demo | | T-9707ND | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Demo: Special Limited Edition | | 647230 | |
| SimCity 3000 (PC Game Sampler) | PC | | Domino's Pizza / Easter Seals | | | |
| Stronghold | PC | 1.00 | Dungeons & Dragons Ultimate Fantasy | | | |
| Silent Steel | PC | 1.82.42.100 | DVD-ROM | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Super Solvers: Spellbound! | PC | 1.0 | Encore | | 10175-CD2 | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Spycraft: The Great Game | PC | | Enhanced DVD-ROM Edition | | | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Syberia (Bonus CD) | PC | 1.0 | Game of the Year Edition | | PCO379CDB | |
| Scrabble | PC | | General Mills | | | |
| Silent Hunter 4: Wolves of the Pacific Silent Hunter 4: Wolves of the Pacific: U-Boat Missions | PC | 1.5 | Gold Edition | | 684589-DVD1 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Sid Meier's Civilization II | PC | 2.42a | Infogrames Rerelease | | | |
| Slot City Jackpot Games (120 Slot Machines) | PC | | Jackpot Games | | CD-4700 | |
| Summer Refresh 2011: 3.65 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2011 3.60 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2010: 3.21 IDU Update (E-M) | PS3 | | Kiosk Demo | | | |
| Spring 2013: Standard IDU 4.31 | PS3 | | Kiosk Demo | | | |
| Spring 2012 Refresh Standard: PS3 IDU 4.11 | PS3 | | Kiosk Demo | | | |
| Star Trek: Judgment Rites | PC | | Limited CD-ROM Collector's Edition | | | |
| Star Trek: New Worlds (Explore New Worlds) | PC | | Limited Edition | | CD-C95-1097-DS | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| The Silver Case | PC | 1.01 | Limited Run Games Limited Edition | | | |
| Sports Champions / Medieval Moves: Deadmund's Quest Combo Disc | PS3 | 01.00 | Not For Resale | | BCUS-90490 | |
| Sega Screams Volume 2 | SS | 2.000 | Not for Resale | | 81077 | |
| Slingo: Wild 7's | PC | | Oregon Lottery | | | |
| Slingo | PC | | Oregon Lottery | | | |
| Systemax Ultimate Software Collection (Disc 9) (Darkened Skye: Disc 1 / Zoboomafoo with the Kratt Brothers Animal Kids) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 8) (Garfield: Mad About Cats / Money Town) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 6) (Women's Fitness / Christina Aguilera: Follow Your Dreams) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 5) (S&S Encyclopedia / Typing Tutor 12) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 4) (Forbes: Corporate Warrior / Starwebs: Web Shop / Writing Tutor / Complete Idiots Guide: Marketing Materials Maker) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 3) (How Many Bugs in a Box? / More Bugs in Boxes / Jim Henson's Muppet Babies: Toyland Train / Miss Spider's Tea Party) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 27) (Star Trek: Deep Space Nine - The Fallen) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 26) (Sabrina, the Teenage Witch: Brat Attack) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 22) (Richard Scarry's: Busy Town) | PC | 2.0 | Original | | | |
| Systemax Ultimate Software Collection (Disc 21) (Mob Rule) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 2) (I See Sue... the T. Rex / Amazons & Aliens / Cheerios: Playtime) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 18) (M&M's: The Lost Formulas) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 14) (Darkened Skye: Disc 2) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 13) (Multimedia Billiards / Astrology Starscopes / Music Match Juke Box Deluxe 6.1 / Extreme Chess / Typing Tutor Jr. / Bumper Wars) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 12) (S&S Encyclopedia of Science / Curious George: Reads, Writes and Spells) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 11) (Pearl Harbor: Zero Hour / Real War) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 10) (Deer Avenger / Ski-Doo X-Team Racing) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 1) (Daria's Inferno / Who Wants to Beat Up a Millionaire) | PC | | Original | | | |
| System Shock | MAC | | Original | | EA 568407 | |
| Symbiocom | PC | | Original | | | |
| Syberia (Disc 2) | PC | 1.0 | Original | | | |
| Syberia (Disc 1) | PC | 1.0 | Original | | | |
| SX Superstar | GC | | Original | | DL-DOL-GS3E-USA | |
| SX Superstar | XBOX | | Original | | AC-016 | |
| Switchball | PC | | Original | | S7275110 | |
| Swingerz Golf | GC | | Original | | DL-DOL-GWGE-USA | |
| SWAT: Target Liberty | PSP | 1.01 | Original | | ULUS-10314 | |
| SWAT: Career Pack (Disc 4) (Police Quest: SWAT) | PC | | Original | | | |
| SWAT 4 (Disc 1) | PC | 1.0 | Original | | | |
| Survivor Ultimate | PC | 1.00.28 | Original | | Part # 23411CD | |
| Survivor | WII | | Original | | RVL-RLNE-USA-B0 | |
| Survival: The Ultimate Challenge | PC | 1.0 | Original | | 31209.101.US | |
| Surf's Up | GC | | Original | | DL-DOL-GXUE-USA | |
| Supreme Commander | XBOX360 | | Original | | AY-2001 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superdead | PC | | Original | | | |
| Superbike 2001 | PC | | Original | | 1421707 | |
| Super Why! The Power to Read | PC | | Original | | 23899-00 | |
| Super Swing Golf | WII | | Original | | RVL-RPYE-USA | |
| Super Solvers: Midnight Rescue! | PC | 1.0 | Original | | | |
| Super Solvers Reading Ages 9-12 | PC | | Original | | SMR744AE-CD | |
| Super Solvers Mission: T.H.I.N.K. | PC | 1.01 | Original | | MEM744CE-CD | |
| Super Solvers Mission: T.H.I.N.K. | PC | 1.0 | Original | | MEM744AE-CD | |
| Super Puzzle Fighter II Turbo | PC | | Original | | | |
| Super PickUps | WII | | Original | | RVL-RQUE-USA-B0 | |
| Super Games for Windows: Volume II | PC | | Original | | | |
| Super Bubble Pop | GC | | Original | | DL-DOL-GBYE-USA | |
| Super Arcade Games: Version 5 | PC | | Original | | | |
| Suncom Technologies Presents: 10 Hit Games by Apogee | PC | | Original | | 63-0647 | |
| The Sum of All Fears | GC | | Original | | DL-DOL-G3ME-USA | |
| The Suffering | XBOX | | Original | | MW-021 | |
| Sub Culture | PC | | Original | | | |
| Su-27 Flanker Mission Disk | PC | | Original | | 2212510-590001 | |
| Stubbs the Zombie in Rebel Without a Pulse | MAC | 1.0 (v418) | Original | | 11010-1DDA | |
| Stronghold FireFly Studios' Stronghold | PC | 1.2 | Original | | | |
| Stronghold | PC | 1.1 | Original | | | |
| Strike Force Bowling | GC | | Original | | DL-DOL-G5BE-USA | |
| Strike Fighters: Project 1 | PC | 1.0.0.1 | Original | | 24147CD | |
| Strife | PC | 1.2 | Original | | | |
| Street Supremacy | PSP | 1.00 | Original | | ULUS-10069 | |
| Street Legal | PC | | Original | | 30975.101.US | |
| Street Hoops | GC | | Original | | DL-DOL-GHPE-USA | |
| Street Hoops | XBOX | | Original | | AV-003 | |
| Street Fighter Series | PC | | Original | | | |
| Street Fighter Series | PC | | Original | | | |
| Street Fighter II | PC | | Original | | 9108 | |
| Street Fighter Alpha 2 | PC | | Original | | | |
| Stray Souls: Dollhouse Story | PC | | Original | | | |
| Strategic Command: European Theater | PC | 1.0 | Original | | | |
| Storybook Workshop | WII | | Original | | RVL-R4VE-USA-B0 | |
| Storybook Weaver Deluxe 2004 | PC | 3.0 | Original | | 483050-CD | |
| Storybook Weaver Deluxe | PC | 1.1 | Original | | Product #HCD642 | |
| Storybook Weaver Deluxe | PC | 1.0 | Original | | | |
| Story Lane Theater 5 | PSX | | Original | | LSP-990145 … | |
| Story Lane Theater 4 | PSX | | Original | | LSP-990144 … | |
| Story Lane Theater 3 | PSX | | Original | | LSP-990143 … | |
| Story Lane Theater 2 | PSX | | Original | | LSP-990142 … | |
| Story Lane Theater 1 | PSX | | Original | | LSP-990141 … | |
| Stonekeep | PC | 1.05 | Original | | CD-ICD-045-0 | |
| Stoked | XBOX360 | | Original | | DE-2003 | |
| The Sting! | PC | v2.0e | Original | | ROTHESTING0004USLAB | |
| A Steven Spielberg Film: Minority Report: Bonus CD-ROM! | PC | | Original | | | |
| Stellar 7 | PC | | Original | | | |
| Stella Gets a New Brain! | PC | 2.0 | Original | | AR-4602 | |
| Stella Gets a New Brain! | PC | | Original | | AR-4601 | |
| Steel Tide | PC | 1.0.0.1 | Original | | | |
| Steel Soldiers | PC | | Original | | | |
| Steel Panthers III: Brigade Command: 1939-1999 | PC | 1.0 | Original | | 2218010-590001 | |
| State of Emergency | XBOX | | Original | | TT-006 | |
| Starsky & Hutch | GC | | Original | | DL-DOL-GT5E-USA | |
| Starship Tycoon | PC | Build 2.24 | Original | | | |
| Starship Troopers | PC | 0.3.2.69 | Original | | P/N 21121-5 | |
| Starshine Legacy: Episode 4: The Riddle of the Dark Core | PC | | Original | | US: 61-0612 04 | |
| Starshine Legacy: Episode 2: Secret of Pine Hill Mansion | PC | | Original | | SLE2, US-61-0603 05 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67023 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67021 | |
| Starball | PC | 1.20 | Original | | | |
| Star Wars: Yoda's Challenge | PC | | Original | | 3520030 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 1.10 | Original | | | |
| Star Wars: X-Wing vs. TIE Fighter (Master Game Disc) | PC | 1.00 | Original | | 2081830 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | MAC | 1.0 | Original | | 2062130 | |
| Star Wars: Rebel Assault | PC | 1.2 | Original | | 632630, CDRM1142600 | |
| Star Wars: Rebel Assault | MAC | | Original | | 634630, CDRM1208410 | |
| Star Wars: Millennium Falcon CD-ROM Playset | PC | | Original | | | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 2) | MAC | 1.0.1 | Original | | 10610-2CDA | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | MAC | 1.0.1 | Original | | 10610-1CDA | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Original | | 0762.05.0 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Original | | 0762.05.0 | |
| Star Wars: Galactic Battlegrounds (Disc 2) (Play) | PC | 1.0 | Original | | 8531831 | |
| Star Wars: Galactic Battlegrounds (Disc 1) (Install) | PC | 1.0 | Original | | 8531830 | |
| Star Wars: Episode III: Revenge of the Sith: Activity Center (Disc 2) | PC | 1.0 | Original | | 682967-CD2 | |
| Star Wars: Empire at War: Forces of Corruption | PC | 1.00.55911 | Original | | 7131930 | |
| Star Wars: Behind the Magic: Vehicles Special Edition | PC | 1.0 | Original | | | |
| Star Wars: Battlefront II | PC | 1.0 | Original | | 3281930 | |
| Star Wars: Anakin's Speedway | PC | | Original | | #3518030 | |
| Star Wars Trilogy CD-ROM: Limited Edition Entertainment Utility | PC | | Original | | | |
| Star Wars Galaxies: 10-Day Trial | PC | | Original | | 8330530 | |
| Star Trek: Voyager: Elite Force | MAC | | Original | | | |
| Star Trek: The Next Generation: Birth of the Federation | PC | | Original | | | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.0 | Original | | | |
| Star Trek: Starfleet Command III | PC | 1.0 | Original | | 32337.101.US | |
| Star Trek: Starfleet Command III | PC | 1.0 | Original | | 32255.101.US | |
| Star Trek: Starfleet Command (Bonus CD) | PC | | Original | | CD-C95-637-1 | |
| Star Trek: Starfleet Academy: Chekov's Lost Missions | PC | | Original | | | |
| Star Trek: Elite Force II (Disc 2) | PC | 1.0 | Original | | 32373.102.US | |
| Star Trek: Elite Force II (Disc 1) | PC | 1.0 | Original | | 32373.101.US | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | CD-ICD-016-0 | |
| Star Trek Pinball | PC | 1.00 | Original | | CD-C95-675-0 | |
| Star Stable: The Autumn Riders | PC | 1.00.0000 | Original | | 61-0803 04 | |
| Star Rangers | PC | | Original | | | |
| Star Defender III | PC | | Original | | CD001697 | |
| Stanley's Sticker Stories | PC | 1.04 | Original | | 381428-CD4/I083ha | |
| Stacked with Daniel Negreanu | XBOX | | Original | | MM-001 | |
| SSX on Tour | XBOX | | Original | | EA-130 | |
| SSX Blur | WII | | Original | | RVL-RSXE-USA | |
| SSX 3 | GC | | Original | | DL-DOL-GXBE-USA | |
| SSI Strategy Collection: Critic's Choice Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| SRS: Street Racing Syndicate | GC | | Original | | DL-DOL-GCSE-USA | |
| SRS: Street Racing Syndicate | XBOX | | Original | | NM-019 | |
| Squad Assault: Second Wave | PC | 1.80 | Original | | | |
| SpyHunter | GC | | Original | | DL-DOL-GSHE-USA | |
| Spycraft: The Great Game (Disc 3) | PC | | Original | | CDD-3110-103-U3 | |
| Spycraft: The Great Game (Disc 3) | MAC | | Original | | CDM-3110-103-U3 | |
| Spycraft: The Great Game (Disc 2) | MAC | | Original | | CDM-3110-102-U3 | |
| Spycraft: The Great Game (Disc 1) | PC | | Original | | CDD-3110-101-U3 | |
| Spycraft: The Great Game (Disc 1) | MAC | | Original | | CDM-3110-101-US | |
| Spyborgs | WII | | Original | | RVL-RSWE-USA-B0 | |
| Spy Fox in "Cheese Chase" | PC | | Original | | | |
| SPRay | WII | | Original | | RVL-RYIE-USA | |
| SportzFreakz | PC | 1.0 | Original | | | |
| Sportsman's Paradise II | PC | 1.0 | Original | | P/N 4-19599CDSL | |
| Spooky Castle | PC | 1.0 | Original | | 11-2057-10 SPC | |
| Split/Second | PSP | 1.00 | Original | | ULUS-10513 | |
| Splashdown | XBOX | | Original | | IG-027 | |
| Spirit of Speed 1937 | DC | 1.001 | Original | | T-8118N | |
| Spine Sense: The Interactive Back Protection Program | CDI | | Original | | | |
| The Spiderwick Chronicles | PC | 1.0 | Original | | S7270810 | |
| Spider-Man: Friend or Foe | WII | | Original | | RVL-RFOE-USA | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| Speed Kings | GC | | Original | | DL-DOL-GDCE-USA | |
| Speed | WII | | Original | | RVL-SPEE-USA-B0 | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Spectral Souls: Resurrection of the Ethereal Empires | PSP | 1.00 | Original | | ULUS-10076 | |
| Spectral Force 3 | XBOX360 | | Original | | AT-2003 | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAE-USA | |
| SpaceChem | PC | 1011 | Original | | | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Bucks | PC | | Original | | | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| Space Ace | PC | | Original | | | |
| South Park: The Stick of Truth | PC | | Original | | 689058-DVD | |
| Sorry! | PC | | Original | | 99040 | |
| Sorry / Boggle / Yahtzee: Triple Pack of Fun | PC | | Original | | Part # 26023CD | |
| Sonic Shuffle | DC | 1.000 | Original | | 51060 | |
| Sonic Adventure 2 | DC | 1.008 | Original | | 51117 | |
| Solitaire Master 4 | PC | 1.0 | Original | | 02-8156-10 | |
| Solitaire Master | PC | | Original | | 20-1280-10 | |
| Solitaire Mania | MAC | | Original | | PART NO. 05SMM-01 | |
| Solitaire Antics Ultimate | PC | 1.0.3L | Original | | | |
| The Software Toolworks Presents: Maniac Sports | MAC | | Original | | 2200820-590001 / I034100 | |
| The Software Toolworks CD Game Pack | PC | | Original | | | |
| Soft Kill | PC | | Original | | | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 3 | PSP | 1.01 | Original | | UCUS-98716 | |
| SocketScan | PALM | Release 108K | Original | | P/N 6210-00108 K | |
| Socket Low Power SDIO WLAN | PPC | Release 142 D | Original | | P/N 6210-00142 D | |
| Soccer Score Soccer | PC | | Original | | | |
| So You Wanna Be a Redneck | PC | | Original | | | |
| So Who's Dr. Rabbit? | PC | | Original | | | |
| Snow Storm | PC | | Original | | 9099 | |
| Snoopy's Grand Adventure | XBOX360 | | Original | | AV-2338 | |
| Snoopy's Campfire Stories | PC | | Original | | | |
| Sniper Elite III | XBOX360 | | Original | | FO-2051 | |
| Snap Dragon | PC | 1.0 | Original | | | |
| Smuggler's Run: Warzones | GC | | Original | | DL-DOL-GSRE-USA | |
| Smiley World: Island Challenge | WII | | Original | | RVL-RIDE-USA-B0 | |
| Smashing Drive | GC | | Original | | DL-DOL-GSDE-USA | |
| SmartKids Challenge One | VIS | | Original | | 25-6176 | |
| Smart Games: Challenge 1 | PC | | Original | | P/N:DSGC1CD0001 | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.2 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.1 | Original | | | |
| Slots Featuring WMS Gaming | PC | 1.0.3 | Original | | | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Slots Adventure: War for Olympus | PC | 1.0 | Original | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Slingo Quest | PC | 0.0.0.104 | Original | | | |
| Slingo 2-Pack | PC | | Original | | | |
| Slingo | PC | | Original | | 99310 | |
| Slave Zero | DC | 1.001 | Original | | T-15106N | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | | Original | | WTY744AE-CD | |
| Slam 'n Jam '96 featuring Magic & Kareem: Signature Edition | SS | 1.000 | Original | | T-15902H | |
| Skylanders: Trap Team | XBOX360 | | Original | | AV-2321 | |
| Skylanders: Trap Team | XBOX360 | | Original | | AV-2321 | |
| Skylanders: Swap Force | XBOX360 | | Original | | AV-2281 | |
| Skylanders: SuperChargers | XBOX360 | | Original | | AV-2335 | |
| Skylanders: Imaginators | XBOX360 | | Original | | AV-2352 | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Skin Style | CDI | | Original | | | |
| Ski-Doo Snowmobile Challenge | XBOX360 | | Original | | VG-2001 | |
| Ski and Shoot | WII | | Original | | RVL-RUME-USA | |
| Sinkha | PC | | Original | | | |
| Sinkha | MAC | | Original | | | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sing 4: The Hits Edition | WII | | Original | | RVL-SIHE-USA-B0 | |
| SiN | PC | 1.01 | Original | | 1000076.101.US | |
| SimTunes | PC | | Original | | 0135-000-0601-A | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-A | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-B | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: Pets | PSP | 1.00 | Original | | ULUS 10130 | |
| The Sims 2: Insider Preview CD | PC | | Original | | 1625207 | |
| The Sims 2 (Disc 4) | PC | 1.0 | Original | | 1472637 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | 1472627 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| The Sims 2 | PSP | 1.00 | Original | | ULUS-10031 | |
| The Simpsons Game | PSP | 1.00 | Original | | ULUS-10295 | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| SimGolf | PC | 1.0 | Original | | 0093-000-0601-A | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | MXB08803894CD2 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | MXB08803894CD1 | |
| SimCity 3000 | MAC | 1.0.557 | Original | | 1500607 | |
| A Silly Noisy House | MAC | | Original | | CDAC 014500 | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Hill: Shattered Memories | PSP | 1.00 | Original | | ULUS-10450 | |
| Silent Hill: Homecoming | XBOX360 | | Original | | KN-2021 | |
| Sierra's School House: Science (Disc 2) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Science (Disc 1) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Math (Disc 2) | PC | | Original | | | |
| Sierra's School House: Math (Disc 1) | PC | | Original | | | |
| Sierra's School House: English (Disc 1) | PC | | Original | | | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| Shrek Super Party | GC | | Original | | DL-DOL-GSYE-USA | |
| Shrek Super Party | XBOX | | Original | | TM-004 | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek Extra Large | GC | | Original | | DL-DOL-GS9E-USA | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shonen Jump's One Piece: Pirates' Carnival | GC | | Original | | DL-DOL-GIPE-USA | |
| Shonen Jump's One Piece: Grand Adventure | GC | | Original | | DL-DOL-GOQE-USA | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Original | | RVL-RIPE-USA | |
| Shogun: Total War: The Mongol Invasion Shōgun: Total War: The Mongol Invasion | PC | 1.00 | Original | | 1430907 | |