Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sable Maze: Forbidden Garden & Twelve Fears | PC | | Original | | 33528010US | |
| Sable Maze: Sullivan River / Norwich Caves | PC | | | | 33471010US | |
| Sacrifice (Editors Press Kit) | PC | | Press Kit | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
| Shadow Man | PC | | Demo | | | |
| Shadow Wolf Mysteries: Curse of the Full Moon / Bane of the Family | PC | | | | 33425010US | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Shining Soul II + Shining Force Assets Shining Soul 2 + Shining Force Assets | PC | | Press Kit | | | |
| Shivers | PC | | Demo | | | |
| Sierra Holiday Software Sampler | PC | | | | | |
| Sierra Products Demo America Online featuring Sierra Online | PC | | | | R00482 | |
| Sierra Super Sampler Sierra On-Line Demos | PC | | | | | |
| Sierra's Sneak Peeks 2 | PC | | Demo | | | |
| SimCoaster: Bonus Disk SimCoaster Extra Value Pack | PC | | | | 4002307 | |
| The Sims 3: Diesel Stuff The Sims 3: Diesel for Successful Living Stuff | PC | 14.0.48.017001 | Original | | 1968807 | |
| The Sims 3: Fast Lane Stuff | PC | 5.0.44.008001 | Original | | 1950207 | |
| The Sims 3: Master Suite Stuff | PC | 11.0.84.014001 | Original | | 1962307 | |
| The Sims 3: Outdoor Living Stuff | PC | 7.0.55.010001 | Original | | 1950307 | |
| The Sims: Party Pack | MAC | | Original | | 10790-1DDA | |
| Sin SiN | PC | 1.01 | Rerelease | | 6236-01 | |
| Slingo Deluxe Slingo Deluxe Bundle | PC | | Original | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| SMBX + Tak 2 Art | PC | | Press Kit | | | |
| Sniper: Ghost Warrior 3 (Disc 4) | PC | | Season Pass Edition | | TCIU01221UND4 | |
| SNK Playmore E3 2006 Games | PC | | Press Kit | | | |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | MAC | | Original | | | |
| Sony PlayStation 2: SCEA Santa Monica Studios: 2004 Press Information: Press Print | PC | | Press Kit | | | |
| Sounds Best on Sound Blaster Every Game Sounds Best on Sound Blaster: 24-bit Advanced HD | PC | | | | | |
| SouthPeak Interactive E3 2000 Electronic Press Kit | PC | | Press Kit | | | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| SquareSoft: E3 2001 Media CD | PC | | Press Kit | | | |
| SSI Strategy Collection: Critic's Choice Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| Star Wars: Jedi Knight Gold Pack | MAC | | Original | | 12280-1DDA | |
| Star Wars: Mac Pack | MAC | | Original | | 12300-1DDA | |
| Stronghold Crusader | PC | | Interactive Demo | | | |
| SWAT 4 | PC | | Demo | | | |
| Sword of the New World: Granado Espada | PC | 2.1.18 | | | | |
| Systemax Ultimate Software Collection (Disc 01) (Daria's Inferno / Who Wants to Beat Up a Millionaire) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 02) (I See Sue... the T. Rex / Amazons & Aliens / Cheerios: Playtime) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 03) (How Many Bugs in a Box? / More Bugs in Boxes / Jim Henson's Muppet Babies: Toyland Train / Miss Spider's Tea Party) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 04) (Forbes: Corporate Warrior / Starwebs: Web Shop / Writing Tutor / Complete Idiots Guide: Marketing Materials Maker) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 05) (S&S Encyclopedia / Typing Tutor 12) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 06) (Women's Fitness / Christina Aguilera: Follow Your Dreams) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 08) (Garfield: Mad About Cats / Money Town) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 09) (Darkened Skye: Disc 1 / Zoboomafoo with the Kratt Brothers Animal Kids) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 10) (Deer Avenger / Ski-Doo X-Team Racing) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 11) (Pearl Harbor: Zero Hour / Real War) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 12) (S&S Encyclopedia of Science / Curious George: Reads, Writes and Spells) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 13) (Multimedia Billiards / Astrology Starscopes / Music Match Juke Box Deluxe 6.1 / Extreme Chess / Typing Tutor Jr. / Bumper Wars) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 14) (Darkened Skye: Disc 2) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 18) (M&M's: The Lost Formulas) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 22) (Richard Scarry's: Busy Town) | PC | 2.0 | Original | | | |
| Systemax Ultimate Software Collection (Disc 26) (Sabrina, the Teenage Witch: Brat Attack) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 27) (Star Trek: Deep Space Nine - The Fallen) | PC | | Original | | | |
| Space Engineers | PC | | Limited Edition | | | |
| Sid Meier's Civilization VI | PC | | Original | | 41829-1 | |
| Los Sims: Superstar (Disc 1) | PC | 1.80 | EA Classics | | MXS08004759D1 | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| Sabrina the Teenage Witch: Brat Attack | PC | | Original | | S02560 | |
| Sacra Terra: Angelic Night | PC | | Original | | | |
| Sacrifice (Scapex Tutorial Video) | PC | | Preproduction | | | |
| Saddle Up: Time to Ride | PC | 1.00.000 | Original | | DPV1.0, PCO437CD | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Same or Different | PC | | Book Bundle | | 08028 | |
| Sammy's Science House | PC | 1.0 | Original | | | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sanitarium (Disc 1) | PC | 1.00 RC15 / Build 836 | Original | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| The Sci-Fi Collection | PC | | Original | | | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Score 4 | PC | | Original | | | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Senha N. 1 | PC | | | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| ShadowGate Classic | PPC | 1.0.0.4 | Original | | 5053626 | |
| Shape Shifter | PC | | Original | | | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shooting Gallery | PALM | | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Sid Meier's Civilization Chronicles (Disc 1) | PC | | Original | | 31074-1.1 | |
| Sid Meier's Civilization Chronicles (Disc 2) | PC | | Original | | 31074-1.2 | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Silent Hunter | PC | 1.0 | Rerelease | | WWD144AE-CD | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Original | | 2211110-590004 | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Ultimate Wargame Collection Volume 2: World War II | | 379280-CD2 | |
| SimCity (Preview Disc) | PC | | Target | | 7298103301 | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Megapak 8 | | 01130-059-0601 | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| SimCity 3000 | PC | | Domino's Pizza / Easter Seals | | | |
| SimCity 3000 | PC | 1.2.673.0 | Rerelease | | 1500117 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | | SimCity Box | | 1907327 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity Enhanced CD-ROM | PC | | Rerelease | | CD-ICD-204-0 | |
| SimCity Enhanced CD-ROM | PC | | Original | | CD-ICD-041-0 | |
| SimClassics: 3 in 1 Pack | PC | | Original | | 0543-000-0601-A | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| The Sims Online: Sampler Disc | PC | | Original | | 4025407 | |
| The Sims Strategy Guide and SimFan Pack | PC | | Pre-Order Bonus | | 1414407 | |
| The Sims | MAC | | | | | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| SimTown | PC | | The Kids Collection | | 1258607 | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sins of a Solar Empire: Trinity | PC | | | | | |
| Sins of a Solar Empire: Trinity | PC | | Rerelease | | | |
| Skunny Kart Combo | PC | | Original | | | |
| Slingo | PC | | Original | | 99310 | |
| Slingo 2-Pack | PC | | Original | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Snap Dragon | PC | 1.0 | Original | | | |
| Snap! Subtraction: Ages 5-8 | PC | | Original | | | |
| SocketScan | PALM | Release 108K | Original | | P/N 6210-00108 K | |
| Software & Document: Master CD for Video Family | PC | 1.20 | Bundle Version Jaton OEM | | | |
| The Software Toolworks CD Deluxe Pack: Version 2 | PC | | Bundle Version Packard Bell OEM | | 2192611-590001 170122 | |
| The Software Toolworks CD Game Pack | PC | | Original | | | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Solitaire Master | PC | | Original | | 20-1280-10 | |
| Solitaire Master 2 | PC | 2.0 | Original | | 11-2806-10 | |
| Solitaire Master 4 | PC | 1.0 | Original | | 02-8156-10 | |
| Sonic & Garfield Pack | PC | | Original | | 85090 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Soundtrack1: The Definitive Xbox Compilation (Disc 2) | PC | | Original | | 314 584 098 2 | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | 2.0 | | | SANSARL-01 | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Spellcasting: Party Pak | PC | 1.0 | Original | | | |
| SpellForce | PC | 1.52.64763 | Platinum Edition | | 11121-1DDA | |
| SpellForce: Universe (Disc 1) | PC | 1.52 | Original | | DVD564CD | |
| Spider-Man 2 | PC | | Demo | | | |
| Spooky Castle | PC | 1.0 | Original | | 11-2057-10 SPC | |
| Sport Image: World Cup 1994 | PC | 2.0 | SoftKey | | WCF344AE-CD | |
| Sports Wurx 1 | PC | | Original | | CDO226 | |
| Square Enix Sampler Disc Volume One: Drakengard Playable Demo | PS2 | 1.00 | | | SLUS 29087 | |
| Star Fox Adventures: Game Preview CD | PC | | Promo | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | CD-ICD-016-0 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Rerelease | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | | | CD-ICD-016-4 | |
| Star Trek: Armada | PC | 1.0 | Original | | 1000913.101.US | |
| Star Trek: Armada | PC | 1.1 | Original | | 1000913.101.US | |
| Star Trek: Armada II | PC | | Star Trek: Action Pack | | 31143.101.US | |
| Star Trek: ConQuest Online | PC | 1.0 | Original | | 1001459.101.US | |
| Star Trek: Deep Space Nine: The Fallen | PC | 11-2000-a | Demo | | | |
| Star Trek: New Worlds (Explore New Worlds) | PC | | Limited Edition | | CD-C95-1097-DS | |
| Star Trek: Starfleet Command (Bonus CD) | PC | | Original | | CD-C95-637-1 | |
| Star Trek: Starfleet Command | PC | 1.01.00 | Rerelease | | CD-C95-637-2 | |
| Star Trek: Starfleet Command III | PC | 1.0 | Original | | 32337.101.US | |
| Star Wars Galaxies: The Complete Online Adventures (Disc 1) | PC | | Original | | 8131830 | |
| Star Wars: Empire at War (Bonus Disc) | PC | | Original, Collector's Edition | | 8541832 | |
| Star Wars: Episode I: Racer | PC | 1.0 | Limited Run Games | | | |
| Star Wars: Episode I: The Phantom Menace: Naboo Missions | PC | 1.0 | Bundle Version OEM | | 3151830, CD-W581950-MLE | |
| Star Wars: Galactic Battlegrounds Saga (Disc 1) | PC | | Original | | 8531030 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 2) | PC | | Original | | 8531031 | |
| Star Wars: Gaming Previews LucasArts Entertainment Company Presents: Star Wars: Gaming Previews | PC | | | | 8220430 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Demo: Special Limited Edition | | 647230 | |
| Star Wars: Knights of the Old Republic Collection | PC | 1.0.3.0 | Original | | | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 2.00.424 | Original | | 3261830R1 v2.1.0.0 | |
| Star Wars: Rebel Assault | PC | 1.2 | Original | | 632630, CDRM1142600 | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, CDRM1221330 | |
| Star Wars: Shadows of the Empire | PC | 1.0 | Rerelease | | 646130 | |
| Star Wars: X-Wing Alliance: Imperial Entanglements | PC | 1.0 | Bundle Version OEM | | 2091831, CD-C951918-VOE | |
| Star Wars: X-Wing vs. TIE Fighter: Flight School | PC | 1.00 | Original | | 2085830 | |
| Starship Troopers | PC | 0.3.2.69 | Original | | P/N 21121-5 | |
| Starship Tycoon | PC | Build 2.24 | Original | | | |
| Starsiege | PC | 1.02 | Original | | | |
| Steel Panthers III: Brigade Command: 1939-1999 | PC | 1.0 | Original | | 2218010-590001 | |
| Steel Panthers III: Campaign Disk | PC | | Original | | 2220210-590001 | |
| Stella Gets a New Brain! | PC | | Original | | AR-4601 | |
| A Steven Spielberg Film: Minority Report: Bonus CD-ROM! | PC | | Original | | | |
| Stonekeep | PC | 1.2 | Rerelease | | CD-ICD-045-1 | |
| Storybook Weaver Deluxe | PC | 1.0 | Original | | | |
| Storybook Weaver Deluxe | PC | 1.2 | Rerelease | | HCD642-CD | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | SBW744DE-CD | |
| Strategic Command: European Theater | PC | 1.0 | Original | | | |
| Stray Souls: Dollhouse Story | PC | | Original | | | |
| Street Fighter Alpha: Warriors' Dreams | PC | | Original | | | |
| Street Fighter Series | PC | | Original | | | |
| Street Fighter Series | PC | | Original | | | |
| Strike Commander | PC | | CD-ROM Classics | | | |
| Strike It Rich! $trike It Rich! | PALM | 1.00 Build 0524c | Original | | | |
| Strong Bad's Cool Game for Attractive People | PC | 1.5.0.0 | Original | | | |
| Stronghold (Bonus Castle: The Tower of London) | PC | | Pre-Order Bonus | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.3 | Interactive Demo | | | |
| The Stronghold Collection | PC | | Original | | 31684-1 | |
| Su-27 Flanker Mission Disk | PC | | Original | | 2212510-590001 | |
| The Suffering (Bonus) | PC | 1.0 | Original | | 28424 CD3 v1.0 | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Suncom Technologies Presents: 10 Hit Games by Apogee | PC | | Original | | 63-0647 | |
| Super Bubble Pop | PC | 1.0 | Original | | 14-9009-10 | |
| Super Game Pak | PALM | | Ultimate Game Collection, Cosmi | | PDA102501, PDA634D1 | |
| Super Huey III | PC | | Cosmi | | CDR 707 D1, SJ 111000 | |
| Super Huey III: Combat & Rescue / Spy Hunter/Sub Attack | PC | | Original | | CDRS409CD1 | |
| Super Meat Boy: Ultra Edition | PC | | Original | | | |
| Superbike Challenge | PC | | Covermount | | | |
| Supercow | PC | | Original | | P/N 61261-CD | |
| Superdead | PC | | Original | | | |
| Supreme Commander (Bonus Disc) | PC | | Original | | | |
| Survivor Ultimate | PC | 1.00.28 | Original | | Part # 23411CD | |
| SWAT 4 (Disc 1) | PC | 31973 | Original | | | |
| Swift Classics Card Games for Windows | PC | | Cosmi | | CDR 720 OD1, SJ 041001 G | |
| SwiftWare | PALM | | Cosmi | | PDA060501, PDAMC1 | |
| Sword of the Stars: Ultimate Collection | PC | 1.6.7 | Original | | | |
| Sid Meier's Civilization II | PC | 2.42a | Risk: Gold Edition | | Product # 99227 | |
| Silent Steel | PC | 1.82.42.100 | DVD-ROM | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Strike Commander / Syndicate Plus / Ultima VIII: Pagan / Wing Commander II | PC | | Bundle Version Creative Labs OEM | | 1213330161 | |
| SpellForce: Universe (Disc 2) | PC | 2.00 | Original | | DVD563CD | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| South Park: The Fractured But Whole (Disc 1) | PC | | Gold Edition | | UBP60802045-DISC1 | |
| South Park: The Fractured But Whole (Disc 2) | PC | | Gold Edition | | UBP60802045-DISC2 | |
| South Park: The Fractured But Whole (Disc 3) | PC | | Gold Edition | | UBP60802045-DISC3 | |
| Soccer Kid Soccer Kid: Feets of Fury!! | PC | | Original | | D134 | |
| Star Trek: D-A-C | PC | | Cosmi | | CDR164D1 | |
| Street Fighter IV: The Ties That Bind (Bonus Disc) | XBOX360 | | Xbox 360 Game Bundle | | CC-2033 | |
| Systemax Ultimate Software Collection (Disc 21) (Mob Rule) | PC | | Original | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Stronghold 3 Gold Stronghold 3: Gold | PC | | Original | | 50080-LBL | |
| Syndicate Plus | PC | | Bundle Version OEM | | | |
| Silent Hunter 4: Wolves of the Pacific Silent Hunter 4: Wolves of the Pacific: U-Boat Missions | PC | 1.5 | Gold Edition | | 684589-DVD1 | |
| Story Hour: Fairy Tales | WII | | Original | | RVL-R4FE-USA | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | Original | | 1672907 | |
| The Sims 2: Double Deluxe The Sims 2: Store Edition | PC | 2.0 | Rerelease | | 1597037 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: Holiday Edition (Disc 2) | PC | 1.0.0.1048 | Original | | 1518917 | |
| The Sims 2: Holiday Edition (Disc 3) | PC | 1.0.0.1048 | Original | | 1518927 | |
| The Sims 2: Holiday Edition (Disc 4) | PC | 1.0.0.1048 | Original | | 1518937 | |
| The Sims 2: University Life Collection | PC | 2.0 | Original | | 1685207 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| Star Wars: Empire at War: Forces of Corruption | PC | 1.00.55911 | Original | | 7131930 | |
| StarCraft (PDF Manual) | PC | | BestSeller Series | | 334854216691 /3 | |