Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Sex | 3DO | | Original | | | |
| Spell It Deluxe | PC | | Original | | | |
| Square Enix E3 2005 Media CD | PC | | Press Kit | | | |
| Square Enix: Final Fantasy VII Advent Children Trailer | PC | | Press Kit | | | |
| StarCraft: Brood War (Expansion Set) | PC | 1.15.2 | StarCraft Battle Chest | | | |
| Stellar 7: Draxon's Revenge | 3DO | | Original | | | |
| Stellar Forces Stellar Forces Expansion Pak: Over 50 Add-On Levels for StarCraft | PC | 2.0 | Original | | | |
| Super GameHouse Collection Super Collapse! / Super Glinx! / Super Nisqually | PC | | MacPlay | | | |
| Star Trek: Starship Creator (Add-On Pack) | PC | | Deluxe | | 0-671-31758-X | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67021 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67023 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Spy Fox in "Dry Cereal" | PC | 1.0 | Original | | 04-70281, Part # 0001407, Part No. 04-00000H1529 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| SimCity 4 Deluxe Edition | MAC | | Original | | 10830-1DDA | |
| Space Invaders XL | NUON | | Original | | 11109 | |
| The Sims 2: Seasons (Expansion Pack) | MAC | 1.7 | Original | | 11610-1DDA | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: House Party (Expansion Pack) | PC | 1.0 | Original | | 1431307, 1431317 | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.1 | Original, Expansion Collection Volume Two, Mega Deluxe | | 1439827 | |
| The Sims: House Party (Expansion Pack) | PC | | Double Deluxe, Expansion Collection Volume One, Mega Deluxe | | 1446107 | |
| The Sims: Vacation (Expansion Pack) | PC | | Original | | 1448807 | |
| The Sims: Vacation (Expansion Pack) | PC | | Expansion Collection Volume Three | | 1448807 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457647 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457657 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459517 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | | | | 1462607 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462607 | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | PC | | | | 1462617 | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462617 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | | Expansion Collection Volume Two | | 1472007 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1472007 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Expansion Collection Volume Two | | 1472017 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Original | | 1472017 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | Original | | 1474007 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| The Sims: Double Deluxe (Bonus CD) | PC | | Double Deluxe, Mega Deluxe | | 1474107 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.286 | Rerelease | | 1491727 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.286 | Rerelease | | 1491737 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.312 | Original | | 1497007 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.312 | Original | | 1497017 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.377 | Rerelease | | 1497027 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.377 | Rerelease | | 1497037 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | Original | | 1526317 | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | | | 1526317 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 1) | PC | 1.10.0.111 | Original, Slim Case | | 1536707 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original, Slim Case | | 1536717 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 1) | PC | 1.13.0.135 | Original, Slim Case | | 1537107 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 2) | PC | 1.13.0.135 | Original, Slim Case | | 1537117 | |
| The Sims 3: World Adventures (Expansion Pack) | PC | 0.2.0.56 | Original, The Sims 3 Expansion Bundle | | 1539307 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 1) | PC | 1.7.0.145 | Original, Slim Case | | 1562107 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 2) | PC | 1.7.0.145 | Original, Slim Case | | 1562117 | |
| Sweet Tooth To Go Sweet Tooth Deluxe | PC | 1.1R | Original | | 1586807 | |
| The Sims 2: Double Deluxe | PC | | Original | | 1597007 | |
| The Sims 2: Double Deluxe (Bonus DVD) | PC | | Original | | 1597027 | |
| The Sims 2: Deluxe (Bonus DVD) | PC | | Original | | 1672917 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | | | 1672927 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | SimCity Box | | 1907317 | |
| The Sims 2: Apartment Life (Expansion Pack) | PC | 1.16.0.179 | Original, Slim Case | | 1907807 | |
| The Sims 3: Late Night (Expansion Pack) | PC | 0.2.0.125 | Original, The Sims 3 Starter Pack | | 1915003301 | |
| The Sims 3: Generations (Expansion Pack) | PC | 1.0.0.1 | Original, The Sims 3 Expansion Bundle | | 1957307 | |
| The Sims 3: Pets (Expansion Pack) | PC | | Original, Limited Edition | | 1962207 | |
| The Sims 3: Seasons (Expansion Pack) | PC | | Original, Limited Edition | | 1978303301 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Rerelease | | 2054130 | |
| Star Wars: X-Wing vs. TIE Fighter (Multiplayer Disc) | PC | 1.00 | Original | | 2081831 | |
| Star Wars: X-Wing Alliance (Disc 1) | PC | 1.0 | Original | | 2091830 | |
| Star Wars: X-Wing Alliance (Disc 1) | PC | 2.02a | Original | | 2091830, 2091830R1 | |
| Star Wars: X-Wing Alliance (Disc 2) | PC | 1.0 | Original | | 2091831 | |
| Star Wars: X-Wing Alliance (Disc 2) | PC | 2.02a | Original | | 2091831, 2091831R1 | |
| The Software Toolworks CD Deluxe Pack 4 | PC | | Bundle Version OEM | | 2192610-590001/1034100, CDRM1170920 | |
| Soldier of Fortune II: Double Helix (Disc 1) | PC | | Original | | 31147.101.US | |
| Star Trek: Voyager: Elite Force: Expansion Pack | PC | 1.20 | Star Trek: Action Pack | | 31151.101.US | |
| Star Trek: Voyager: Elite Force: Expansion Pack | PC | 1.20 | Original | | 31151.101.US | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | 1.00 | Collector's Edition | | 3181830 | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | 1.00 | Collector's Edition | | 3181831 | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | 1.00 | Collector's Edition | | 3181832 | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.0.0.9 | Original | | 35033.101.US | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.0.0.9 | Original | | 35033.102.US | |
| Sam & Max Hit the Road | PC | | Rerelease, The LucasArts Archives Vol. I | | 634430 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | | Original | | 635930 | |
| The Sims 3: Island Paradise (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7301203301 | |
| The Sims 3: Into the Future (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7308903401 | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 2.0 | Bundle Version Diamond OEM | | 75000203-100 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051831 | |
| Star Wars: X-Wing: Collector's CD-ROM / Star Wars: X-Wing vs. TIE Fighter: Flight School | PC | | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061830 | |
| Soldier of Fortune II: Double Helix | XBOX | | Original | | AV-027 | |
| SBK X: Superbike World Championship | PS3 | 01.00 | Original | | BLUS-30683 | |
| Street Fighter X Tekken | PS3 | 01.01 | Original, Special Edition | | BLUS-30722 | |
| SSX | PS3 | 01.00 | Original | | BLUS-30849 | |
| Software JukeBox: Home & Entertainment Edition: Vol. 1 No. 1 | PC | | Original | | CDRM1006830 | |
| Sonic Gems Collection | GC | | Original, Player's Choice | | DL-DOL-G2XE-USA | |
| Star Fox: Assault | GC | | Original, Player's Choice, Player's Choice (Best Seller) | | DL-DOL-GF7E-USA | |
| Star Fox Adventures | GC | | Original | | DL-DOL-GSAE-USA | |
| Star Fox Adventures | GC | Rev 1 | Player's Choice | | DL-DOL-GSAE-USA | |
| SSX Tricky | GC | | Original | | DL-DOL-GSTE-USA | |
| Star Wars: The Clone Wars | GC | | Original, Player's Choice | | DL-DOL-GSXE-USA, DL-DOL-GSXE-USA-01 | |
| Sonic Riders | GC | | Original, Player's Choice | | DL-DOL-GXEE-USA | |
| SSX on Tour | GC | | Original | | DL-DOL-GXOE-USA | |
| Sphinx and the Cursed Mummy | GC | | Original | | DL-DOL-GXPE-USA | |
| Sonic Adventure DX: Director's Cut | GC | | Original, Player's Choice | | DL-DOL-GXSE-USA | |
| SSX | XBOX360 | | Original | | EA-2413 | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.0 | Original | | J-124-40-101 | |
| Star Wars: Math: Jabba's Game Galaxy | PC | | Original, Scholastic | | P/N CDR5077850 | |
| Spy Fox in "Dry Cereal" | PC | 2.00 | Original | | Part #04-00000H1407 | |
| Spy Fox in "Cheese Chase" | PC | 2.00 | Rerelease | | Part No. 04-15244CD | |
| Spy Fox 2: "Some Assembly Required" | PC | 1.0.0.1 | Original | | Part No. 04-17571CD | |
| Spy Fox in "Hold the Mustard" | PC | 1.0 | Original | | Part No. 04-17574CD | |
| Spy Fox: "Operation Ozone" | PC | | Original | | Part No. 04-22394CD | |
| Six Flags Fun Park | WII | Rev 1 | Original | | RVL-R6FE-USA-B0 | |
| Spy Fox in "Dry Cereal" Spy Fox: Dry Cereal | WII | | Original | | RVL-RDLE-USA | |
| Super Mario Galaxy | WII | | Original, Nintendo Selects | | RVL-RMGE-USA, RVL-RMGE-USA-B0 | |
| Showtime Championship Boxing | WII | | Original | | RVL-RSYE-USA | |
| Spectrobes: Origins | WII | | Original | | RVL-RXXE-USA-B0 | |
| Super Mario Galaxy 2 | WII | | Original, Nintendo Selects | | RVL-SB4E-USA-B0 | |
| Skylanders: Swap Force | WII | | Starter Pack | | RVL-SVXE-USA-B0 | |
| Skylanders: Swap Force | WII | Rev 1 | Starter Pack | | RVL-SVXE-USA-B1 | |
| StarCraft: Brood War (Expansion Set) | PC | 1.05 | StarCraft Battle Chest | | S02416, S0241621 | |
| StarCraft: Brood War (Expansion Set) | PC | 1.04 | Original | | S03995 | |
| SSX | PS2 | 1.00 | Original | | SLUS 20095 | |
| SSX 3 | PS2 | 1.00 | Original, Greatest Hits | | SLUS 20772 … | |
| Super Monkey Ball Deluxe | PS2 | 1.00 | Original | | SLUS 20918 | |
| Sprint Cars: Road to Knoxville | PS2 | 1.02 | Original | | SLUS 21418 | |
| Samurai Warriors 2: Xtreme Legends | PS2 | 1.02 | Original | | SLUS 21726 | |
| Sphinx and the Shadow of Set Sphinx and the Cursed Mummy | PS2 | 1.01 | Demo | | SLUS 29057 | |
| Square Enix Sampler Disc Volume Two: Front Mission 4 Playable Demo | PS2 | 1.00 | | | SLUS 29098 | |
| SSX on Tour | PS2 | 1.00 | Demo | | SLUS 29161 | |
| San Francisco Rush: Extreme Racing | PSX | | Original | | SLUS-00505 | |
| Street Fighter EX Plus Alpha | PSX | | Original, Fighters Edge | | SLUS-00548 | |
| Street Fighter EX2 Plus | PSX | | Original | | SLUS-01105 | |
| Skydiving Extreme | PSX | | Original | | SLUS-01392 | |
| Street Fighter EX3 | PS2 | 1.00 | Original | | SLUS-20130 | |
| SSX Tricky | PS2 | 1.00 | Original | | SLUS-20326 | |
| Serious Sam: Next Encounter | PS2 | 1.01 | Original | | SLUS-20907 | |
| Sherlock Holmes: Consulting Detective | PCE | | Original | | TGXCD1011 | |
| Splash Lake | PCE | | Original | | TGXCD1025 | |
| SSX on Tour | PSP | 1.00 | Original | | ULUS-10042 | |
| Street Fighter Alpha 3 Max | PSP | 1.00 | Original | | ULUS-10062 | |
| Star Wars: The Clone Wars + Tetris Worlds | XBOX | | Bundled with Xbox: Limited Edition Package, Promotional Offer | | XL-013 | |