| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Sacred (Disc 1) | PC | | |  | |  |
| Sacred (Disc 2) | PC | | | | | |
| Sacred Gold | PC | 2.0.2.24 | GSP White Label: Reload | | 1579B | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Sacred Gold | PC | 2.0.2.24 | GSP White Label | | 1579A | |
 | Sacred Gold | PC | | Linux (LGP) | | | |
| Saint & Sinner | PS2 | 1.01 | Original | | SLES-55076 | |
 | Saints Row (Assets Disk) | PC | | Press Kit | | | |
| Saints Row IV | PS3 | 01.01 | Commander in Chief Edition | | BLES-01954 … | |
| Sakura Wars: So Long, My Love | WII | | Original | | RVL-SAKP-UKV-E0 | |
 | Sam & Max: Season 1
Sam & Max: Sezon 1 | PC | 1.0 | Original, eXtra Klasyka XK Hit | | SM ENG | |
| Sam & Max: Season One
Sam & Max Save the World | PC | | Original | | ROSAMMAX000000DVD | |
| Samurai Aces | PS2 | 1.00 | Original | | SLES-53872 | |
| Samurai Shodown Anthology | WII | | Original | | RVL-RSSP-EUR | |
| Samurai Shodown Anthology | PS2 | 1.01 | Original | | SLES-55292 | |
| Samurai Shodown Anthology | PSP | 1.01 | Original | | ULES-01211 | |
| Samurai Shodown III | PSX | | Original | | SCES-00563 | |
| Samurai Warriors | PS2 | 1.01 | Original | | SLES-52551 | |
| Samurai Warriors 2 | PC | | Original | | 04929UK | |
| Samurai Warriors 2 | PS2 | 1.01 | Original | | SLES-54340 | |
| Samurai Warriors 2: Xtreme Legends | PS2 | 1.02 | Original | | SLES-55108 | |
| Samurai Warriors: State of War | PSP | 1.00 | Original | | ULES-00297 | |
| Samurai Warriors: Xtreme Legends | PS2 | 1.00 | Original | | SLES-53002 | |
| Savage 2: A Tortured Soul | PC | 01.00.00 | Original | | | |
| Scarface: Money. Power. Respect. | PSP | 1.02 | Original, Promo | | ULES-00545 … | |
| Scarface: The World Is Yours | XBOX | | Original | | VU-063 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCU-AUS-B0 | |
| Scarface: The World Is Yours | PS2 | 1.00 | Original | | SLES-54271 | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | S1004042 | |
| Scarface: The World Is Yours | PC | 1.00.1 | Rerelease | | S1004045 | |
 | SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 1) | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 2) | PC | | Press Kit | | | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCP-UKV-B0 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2039 | |
| Scene It? Bright Lights! Big Screen! | PS3 | 01.01 | Original | | BLES-00731 | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3P-UKV | |
| Scooby-Doo! Night of 100 Frights | GC | | Original | | DL-DOL-GIHP-UKV | |
| Scooby-Doo! Night of 100 Frights | PS2 | 1.01 | Original | | SLES-51017 | |
| Scooby-Doo! Who's Watching Who? | PSP | 1.00 | Original | | ULES-00571 | |
| Scooter Racing | PSX | | Original | | SLES-03770 | |
| SCORE International Baja 1000: World Championship Off Road Racing | WII | | Original | | RVL-RJCP-EUR-B0 | |
| SCORE International Baja 1000: World Championship Off Road Racing | PS3 | 01.00 | Original | | BLES-00421 | |
| SCORE International Baja 1000: World Championship Off Road Racing | PS2 | 1.00 | Original | | SLES-55295 | |
| SD Media Launcher for GameCube / Wii | GC | | Unlicensed | | | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLES-53804 | |
| Secret Files: Tunguska | PC | 1.03 | Original, Xplosiv | | ECD008099M 00060722-01, ECD900019D 00060810-01, XP-2221 3026412 | |
| Secret Service | PS2 | 1.00 | Original | | SLES-55330 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51707 | |
| The Seed: Warzone | PS2 | 1.00 | Original | | SLES-51715 | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSP-EUR | |
| Sega Soccer Slam | XBOX | | Original | | IG-041 | |
| Sega Soccer Slam | PS2 | 1.01 | Original | | SLES-51125 | |
| Sega³ Demo | PS2 | 1.10 | | | SCED-50761 | |
| Selector Demo 03
PlayStation 2 Official Demo Disc Retail Edition 3 | PS2 | 1.00 | | | SCED-51146 | |
| Selector Demo 04
PlayStation 2 Official Demo Disc Retail Edition 4 | PS2 | 1.00 | | | SCED-51269 | |
| Selector Demo 05
Selector Demo 05 April 2003: June 2003 | PS2 | 1.00 | | | SCED-51683 | |
| Serious Sam 3: BFE | PC | | Original | | MTC000692-D | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Original | | RVL-SS4U-AUS-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Original | | RVL-SS3U-AUS-B0 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Settlers II, The: Veni, Vidi, Vici | PC | 1.51 | Rerelease | | | |
| The Settlers III: Gold Edition (Disc 2) | PC | 1.25.0.125 | Original | | | |
| Shadow Hearts | PS2 | 1.01 | Original | | SLES-50677 | |
| Shadow of Ganymede | PS2 | 1.03 | Original | | SLES-53345 … | |
| Shadow Warrior | PC | Final 1.5 | Special Edition | | MTC000875-D | |
| Shadowgrounds | PC | 1.02 | Original | | UGL0001 | |
| Shadowgrounds | PC | | Linux (LGP) | | | |
| Shadowgrounds Survivor | PC | | Linux (LGP) | | | |
| Shadowrun | PC | 1.0 | Original | | 0307 Part No. X13-37202-01 | |
| Shakedown: Hawaii | WII | | Original | | RVL-SEVP-EUR-B0 | |
| Shaun Palmer's Pro Snowboarder | PS2 | 1.00 | Original | | SLES-50400 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Skateboarding | PS3 | 01.00 | Original | | BLES-01004 | |
| Shaun White Snowboarding: World Stage | WII | | Original | | RVL-R6NP-UKV-B0 | |
| ShellShock: Nam '67 | PC | 1.0 | Original | | MSHOCVEN81 | |
| ShellShock: Nam '67 | PC | 1.0 | MAD | | | |
| ShellShock: Nam '67 | PS2 | 1.04 | Original, Promo | | SLES-51981 | |
 | ShellShock: Nam '67 | PC | | The Games Collection | | | |
| Shenmue II | XBOX | | Original | | MS-050 | |
| Sherlock Holmes Trilogy | PC | | Original | | | |
| Sherlock Holmes Versus Jack the Ripper | PC | 1.00.0777 | Original | | | |
| Sherlock Holmes: Consulting Detective | MCD | | Original | | 4650 | |
| Sherlock Holmes: The Awakened | PC | | Original | | | |
| Sherlock Holmes: The Awakened | PC | 1.00.0000 | Original | | | |
| Sherlock Holmes: The Awakened: Remastered Edition | PC | 1.0 | Rerelease | | Part No. ESS845 | |
| Shifters | PS2 | 1.01 | Original | | SLES-50644 | |
| Shin Megami Tensei: Devil Summoner: Raidou Kuzunoha vs. the Soulless Army | PS2 | 1.00 | Original | | SLES-54629 | |
| Shin Megami Tensei: Digital Devil Saga | PS2 | 1.00 | Original | | SLES-53458 … | |
| Shin Megami Tensei: Digital Devil Saga 2 | PS2 | 1.01 | Original | | SLES-54555 | |
| Shin Megami Tensei: Persona 2: Innocent Sin | PSP | 1.00 | Collector's Edition | | ULES-01557 | |
| Ship Simulator 2008 | PC | 1.4.2 Build 1038 | Rerelease | | | |
| The Ship | PC | | Original | | TSH854AB-CD | |
| Shockwave Assault | SS | 1.000 | Original | | T-5005H-50 | |
| Shogun's Blade | PS2 | 1.01 | Original | | SLES-53400 | |
| Shonen Jump's One Piece: Grand Adventure | PS2 | 1.01 | Original | | SLES-54165 | |
| Shonen Jump's One Piece: Grand Battle | PS2 | 1.00 | Original | | SLES-53579 | |
| The Shoot | PS3 | 01.00 | Original | | BCES-01058 | |
