Region | Title | System | Version | Edition | Languages | Serial | Status |
| S²: Silent Storm (Disc 1) | PC | | Gold Edition | | ROSILENTST0007lab1 | |
| Sensible World of Soccer | PC | 1.0 | Original | | | |
| Sim Explosion: Extra Levels for Sim City & Sim City 2000 | PC | | Original | | | |
| Sonic R | PC | | Xplosiv | | EI-1263 | |
| Syberia Collection | PC | | Adventure Classics | | | |
| The Sims | PC | 1.0 | Original, The Sims: Collector's Edition | | MXE08902626D | |
| SimCity 3000 | PC | | Dice | | DCG 013290 | |
| SimCity 3000 | PC | | EA Classics | | MXX08803493D | |
| SimCity 3000 | PC | 1.0.557.0 | Original | | MXX08801496D | |
| SimCity 3000 World Edition | PC | 2.0.949.0 | Original | | MXX08903180D | |
| S.W.I.N.E. (Disc 2) Ś.W.I.N.I.A. | PC | | Original | | | |
| Sacrifice | PC | | Sold Out Software | | | |
| Scarab S.C.A.R.A.B. | PC | | Original | | EAE08801181D | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Scrabble CD-ROM | PC | | Original | | 23713-0726 Rev a | |
| Screamer | PC | | Original, White Label | | | |
| Screamer | PC | | Original | | | |
| Screamer Rally | PC | | Sold Out Software | | | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 32609.101.UK | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 32609.102.UK | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 32609.103.UK | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 32609.104.UK | |
| Sega Rally 2 (Disc 1) (Install Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-1 | |
| Sega Rally 2 (Disc 2) (Play Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-2 | |
| Sega Rally Championship PC | PC | 1.0 | Original | | MK 85048-50 | |
| Sega Worldwide Soccer PC | PC | | Original | | MK 85056-50 | |
| Shadow Company: Left for Dead | PC | | Original | | | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original | | | |
| Shogo: Mobile Armor Division | PC | 1.0 | Original | | CD 651/02 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | EAE08801965D1 | |
| Shogun: Total War (Disc 2) | PC | 1.0 | Original | | EAE08801965D2 | |
| Shrek 2 | PC | | Original | | 32585.101.UK | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | ORE08901524D | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | MP 191 307 DO1R | |
| Sid Meier's Civilization III | PC | 1.07f | Original, Best of Atari | | 1012661 | |
| Sid Meier's Civilization III: Play the World | PC | 1.14f | Rerelease | | 1007417/2 | |
| Sid Meier's SimGolf | PC | 1.03 | Original, EA Classics | | EAX08803576D | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | | | 1058-030-0601-0-A | |
| Simon the Sorcerer | PC | | Rerelease | | | |
| Simon the Sorcerer II: The Lion, the Wizard and the Wardrobe Simon the Sorcerer II | PC | 1.1 | Rerelease | | | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | BestSeller Series | | S1001615 | |
| The Simpsons: Hit & Run (Disc 2) | PC | 1.0 | BestSeller Series | | S1001616 | |
| The Simpsons: Hit & Run (Disc 3) | PC | 1.0 | BestSeller Series | | S1001617 | |
| SiN | PC | 1.00 | Original | | 1000076.101.UK | |
| SiN (Patch v1.01) | PC | 1.01 | Original | | 1000076.102.UK | |
| The Sly Trilogy | PS3 | 01.00 | Classics HD, Promo | | BCES-00982 | |
| Small Soldiers: Globotech Design Lab | PC | 1.0.16.57 | Original | | 44106.102 | |
| Small Soldiers: Squad Commander | PC | | Original | | 44107.102 | |
| Solar Crusade | PC | | Dice | | DMM 011396 | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Spartan | PC | | Original | | JFC000784 | |
| Speed Busters BGamer 045 (Disc 1) | PC | 1.01 | Focus Essential, Covermount | | ESS262 | |
| Star General | PC | 1.0 | Original | | CS090339 | |
| Star Trek Pinball | PC | 1.00 | Covermount | | CD-C95-675-EME | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.0 | Original, Award Winners No. 1 | | EI-1041 | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | | LucasArts Classic | | 41121.101.UK | |
| Star Wars: Battlefront (Disc 2) | PC | | LucasArts Classic | | 41121.102.UK | |
| Star Wars: Battlefront (Disc 3) | PC | | LucasArts Classic | | 41121.103.UK | |
| Star Wars: Episode I: Battle for Naboo | PC | | Original | | 41074.101.UK | |
| Star Wars: Galactic Battlegrounds (Disc 1) (Install) | PC | 1.0 | Original | | 41097.101.UK | |
| Star Wars: Galactic Battlegrounds (Disc 2) (Play) | PC | 1.0 | Original | | 41097.102.UK | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Original | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Original | | 9521831 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.00 | Original | | 41118.101.UK | |
| Star Wars: Knights of the Old Republic (Disc 2) | PC | 1.00 | Original | | 41118.102.UK | |
| Star Wars: Knights of the Old Republic (Disc 3) | PC | 1.00 | Original | | 41118.103.UK | |
| Star Wars: Knights of the Old Republic (Disc 4) | PC | 1.00 | Original | | 41118.104.UK | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 2.00 | Original | | 41127.101.UK | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 2) | PC | 2.00 | Original | | 41127.102.UK | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 3) | PC | 2.00 | Original | | 41127.103.UK | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 4) | PC | 2.00 | Original | | 41127.104.UK | |
| Star Wars: Pit Droids | PC | 1.0 | Original | | | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PC | | | | | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | | | | | |
| Star Wars: Shadows of the Empire | PC | 1.0 | Original | | | |
| Star Wars: Supremacy | PC | 1.0 | Original | | 8511830 | |
| Star Wars: X-Wing Alliance (Disc 1) | PC | 1.0 | Original | | 3000011.101.UK | |
| Star Wars: X-Wing Alliance (Disc 2) | PC | 1.0 | Original | | 3000011.102.UK | |
| Star Wars: X-Wing vs. TIE Fighter (Multiplayer Disc) | PC | | Original | | 2081830 | |
| Star Wars: X-Wing vs. TIE Fighter (Master Game Disc) | PC | | Original | | 2081830 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 2.0.0 | Original | | 7091830 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.5 | Original | | | |
| StarCraft | PC | 1.0 | Original | | S0012152 | |
| StarCraft | PC | 1.15.2 | BestSeller Series | | S054801E | |
| StarCraft: Brood War (Expansion Set) | PC | 1.15.2 | BestSeller Series | | S054802E | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | 1.0 | Original, Ubisoft eXclusive | | 0100 Part No. X04-94355 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | 1.0 | Original, Ubisoft eXclusive | | 0100 Part No. X04-94357 | |
| Steel Panthers | PC | 1.1 | Original | | CS090218 | |
| Steel Panthers II: Modern Battles | PC | 1.00 | Original | | CS090345 | |
| Steel Panthers III: Brigade Command: 1939-1999 | PC | 1.0 | Original | | CS090545 | |
| Stonekeep | PC | 1.2 | Covermount | | CD-ICD-045-EME | |
| Streets of SimCity | PC | | Dice | | DCG 012187, DMM 012194 | |
| Su-27 Flanker | PC | 1.1 | | | CD090269 | |
| Sudden Strike | PC | 1.1 | Sudden Strike Anthology | | PF5003/UK2 | |
| Sudden Strike Forever | PC | 1.21 | Sudden Strike Anthology | | PF5003/UK2 | |
| Sudden Strike II | PC | 2.0 | Sudden Strike Anthology | | PF5003/UK2 | |
| The Suffering: Ties That Bind (Disc 1) | PC | 1.00.0000 | Original | | 5037930060199, 5037930060243 | |
| The Suffering: Ties That Bind (Disc 2) | PC | 1.00.0000 | Original | | 5037930060199, 5037930060243 | |
| The Suffering: Ties That Bind (Disc 3) | PC | 1.00.0000 | Original | | 5037930060199, 5037930060243 | |
| Super Solvers: Spellbound! | PC | 1.1 | Covermount, Softkey | | SLB844AB-CD | |
| Surface Tension | PC | | Sold Out Software | | | |
| SWAT 4 (Disc 1) | PC | | Gold Edition (BestSeller Series) | | S2135601 | |
| SWAT 4 (Disc 2) | PC | 1.0 | Rerelease, Gold Edition: BestSeller Series | | S1002656, S2135602 | |
| SWAT 4: The Stetchkov Syndicate | PC | | Gold Edition (BestSeller Series) | | S2135603 | |
| SWIV 3D | PC | | Original | | SCI1901UK | |
| System Shock 2 | PC | 1.15 | Original | | LGE08902537D | |
| Soldier of Fortune | PC | 1.03 | Original | | 1000910.101.UK | |
| Sid Meier's Civilization | PC | | Powerplus | | PPX90128D01R | |
| Sid Meier's Civilization II | PC | | Original | | MPX91260DO1R | |
| Sid Meier's Civilization II | PC | | Best of Infogrames | | CIV2PCB0GB/A | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.032 | Original | | S343BBZZ12ZZZ | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.02a | Original | | 32573.101.3L | |
| Sensible World of Soccer '96/'97 (Upgrade PC CD-ROM Disc) | PC | | Original | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Stupid Invaders (Disc 1) | PC | | Original | | | |
| Stupid Invaders (Disc 2) | PC | | Original | | | |
| Stupid Invaders (Disc 3) | PC | | Original | | | |
| Stupid Invaders (Disc 4) | PC | | Original | | | |
| Starsky & Hutch | PC | | Rerelease | | EI-1510 | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD008457M, ECD900237D | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original, TakeAdvantage | | | |
| Sid Meier's Civilization III: Conquests | PC | 1.0 | Original | | 1011794 | |
| Sid Meier's Civilization IV: Warlords | PC | 2.0 | Original | | | |
| Sid Meier's Pirates! (Disc 1) | PC | 1.0 | Original | | 1013172 | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0 | Original | | 1015406 | |
| Soldier of Fortune II: Double Helix (Disc 2) | PC | 1.00 | Original | | 31147.102.UK | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | Original | | EAX08902788D | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | PC | 1.0 | Rerelease | | 32607.101.4L | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 2) | PC | 1.0 | Original | | 32607.102.4L | |
| Severance: Blade of Darkness | PC | 1.0 | Original | | MSEVCDEU00, MSEVCDUK00 | |
| Syndicate Wars | PC | | Original | | BFX05100371D | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) | PC | 1.0 | Original, LucasArts Classic | | 41123.101.IT, 41123.101.UK | |
| Star Wars: Republic Commando (Disc 2) | PC | 1.0 | Original, LucasArts Classic | | 41123.102.IT, 41123.102.UK | |
| Sleep Walker | PC | | Megaware Multimedia | | art. P006 | |