Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sacred Gold | PC | 2.0.2.24 | GSP White Label | | 1579A | |
| Sali Mali 123 | PC | 2.0 Build 216 | Original | | TPPC27 | |
| Savage Arena | PC | | Dixons | | | |
| Science & Nature: Elements Science 1: Elements | ARCH | 1.00 | Original | | | |
| Science & Nature: Materials Science Series II: Materials | ARCH | 1.00 | Original | | | |
| Science: Electricity and Magnetism: Secondary Edition Science 3: Electricity and Magnetism | ARCH | 1.0 | Original | | | |
| Scooby-Doo! Phantom of the Knight | PC | | SoftKey | | SPK854BB-CD | |
| Scrabble Interactive: 2007 Edition | PC | 1.1.0 | Ubisoft eXclusive / Focus Essential | | ESS760 | |
| Screamer | PC | | Sold Out Extreme | | | |
| Sea Plane Adventures Sea Plane Adventures for FS2002/2004 | PC | | Original | | | |
| Search & Rescue 3 | PC | | Original | | ASS256A181-0001-0001-02 | |
| Seashore Life | ARCH | 1.0 | Original | | | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Touring Car Championship | PC | | Fair Game: Quality Value | | FG-1306 EUROPEAN | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers IV | PC | 1.06.811 | Original | | | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Original | | 5004220 | |
| Shattered Steel | PC | 1.08 | | | CD-ICD-201-M9 | |
| Ship Simulator 2008 | PC | 1.4.2 Build 1038 | Rerelease | | | |
| The Ship | PC | | Original | | TSH854AB-CD | |
| Showcase Pool: UK Style | PC | | | | | |
| Shrek 2 | XBOX | | Classics | | AV-055 | |
| Shuffle15 | PC | | Covermount | | | |
| Sid Meier's Civilization | PC | 474.03 | Powerplus | | PPX90128D01R | |
| Sid Meier's Civilization Chronicles: Digital Game Manuals for Civ I, Civ II, Test of Time, Civ III Complete and Civ IV | PC | | Original | | 51989/CD2 | |
| Sid Meier's Civilization III Complete (Disc 1) | PC | | Sid Meier's Civilization Chronicles | | 51989/CD3 | |
| Sid Meier's Civilization III Complete (Disc 1) | PC | | PC Gamer Presents | | | |
| Sid Meier's Civilization IV | PC | 1.61 | Sid Meier's Civilization Chronicles | | 51989/DVD1 | |
| Sid Meier's Civilization IV: Playable Demo Disk | PC | | Demo | | | |
| Sid Meier's Civilization IV: Warlords | PC | | Original | | | |
| Silly Soccer | PC | 1.0 | Original | | | |
| SimCity 3000 UK Edition | PC | | Sold Out Software | | | |
| The Sims 2: FreeTime (Expansion Pack) | PC | | | | MXX07705984D | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | MXX08005576D | |
| The Sims Medieval: Pirates & Nobles | PC | 2.0.109.00001 | Original | | MXX09208325D | |
| Skateboard Crazy | PC | | | | | |
| Skipper & Skeeto: The Great Treasure Hunt | PC | | GSP/PC Ace Covermount | | GSPCD336A | |
| Sniper: Path of Vengeance | PC | 1.25 | Original | | | |
| The Soft Rock Games Collection CD | ARCH | | Original | | | |
| The Soft Rock Software Collection | ARCH | Edition 1 | Original | | | |
| Softkey Home/Family Bundle | PC | | Original | | HFB344CB-CD | |
| SonicFury: Software and Documentation | PC | 2 | | | 8/00 11K39 | |
| Spearhead | PC | | Covermount | | | |
| Speed Freak | PC | | Covermount | | | |
| Spider-Man Databank | PC | | Original | | | |
| SPQR: The Empire's Darkest Hour | PC | | Original | | | |
| Springy | PC | | Original | | | |
| Star Command: Surface Skimmer | PC | | Original | | | |
| Star Soccer Skills | PC | | Covermount | | | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) สตาร์วอร์ส รีพับลิคคอมมานโด | PC | 1.0 | Original | | | |
| Star Wars: Republic Commando (Disc 2) สตาร์วอร์ส รีพับลิคคอมมานโด | PC | 1.0 | Original | | | |
| Starmageddon 2: Project Freedom | PC | | Original | | | |
| Stars! | PC | 2.70i | Grabit | | GDL051 | |
| Starship Titanic (Disc 1) Douglas Adams: Starship Titanic | PC | 1.00.42 | Rerelease | | | |
| Starship Titanic (Disc 2) Douglas Adams: Starship Titanic | PC | 1.00.42 | Rerelease | | | |
| Starship Titanic (Disc 3) Douglas Adams: Starship Titanic | PC | 1.00.42 | Rerelease | | | |
| Starsky & Hutch | PC | 1.0 | Covermount: Limited Edition - Free with The Sun | | SUN039a | |
| Strange Cases: The Tarot Card Mystery | PC | | Original | | ESS827 | |
| Straw Harvest Stroh-bergung | PC | 1.1.0 | Original | | | |
| The StrongARM CD-ROM | ARCH | | Original | | | |
| Stronghold Crusader II | PC | | Original | | MTF000740-D | |
| Stronghold Legends: Special Edition (Additional Campaigns) | PC | | Special Edition | | | |
| Su Doku Classic 2 | PC | 2.0 | Covermount | | | |
| Super Meat Boy | PC | | Blue Bird | | | |
| Superbike World Championship | PC | | Bundle Version Time OEM | | | |
| Supermarket Mania | PC | | Original | | ESS772 | |
| Supreme Commander | PC | 1.0.3189 | Gold Edition | | SupCom_EFIS | |
| Supreme Commander | PC | 1.0.3189 | Focus Essential | | ESS762 | |
| Supreme Commander: Forged Alliance | PC | 1.5.3596 | Gold Edition | | 4005209099301 / 4005209099295 | |
| Swing | PC | | Demo | | | |
| SWIV 3D (Playable Demo) | PC | v5.25 | | | | |
| Sword of the Stars II: Enhanced Edition | PC | | Enhanced Edition | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Bonus DVD) | PC | | Radiation Edition | | 4005209088800 / 4005209089029, 4005209089036 / 4005209089006, 4005209089180, 4005209089340 / 4005209089012 | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | | Original, Radiation Edition | | | |
| Sacred Gold | PC | 2.0.2.24 | GSP White Label: Reload | | 1579B | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0.1.8 | SoftKey | | SGW854BB, SGW854BB-CD | |
| Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| The Settlers: Heritage of Kings | PC | 1.03.0190 | Ubisoft eXclusive / Focus Essential, The Settlers: Heritage of Kings / CSI: Crime Scene Investigation / Rayman 3: Hoodlum Havoc | | 5003950, ESS626 | |
| Sheep | PC | | Covermount, Absolute Gaming | | EI-1246 | |
| Sheep | PC | 1.0.0.1 | Xplosiv | | EI-1381 | |
| Shogun: Total War | PC | | Demo | | EAX08901965DD1 | |
| Shogun: Total War: Gold Edition | PC | | Green Pepper, Total War: Eras | | DIS-TWESHOG, SEGA-PC097-R | |
| Sid Meier's Civilization III | PC | 1.07f | Original, Best of Atari | | 1012661 | |
| Sid Meier's Civilization III Complete (Disc 2) | PC | | Sid Meier's Civilization Chronicles, Green Pepper | | 51989/CD4 | |
| Sid Meier's Civilization III Complete (Disc 3) | PC | | Sid Meier's Civilization Chronicles, Green Pepper | | 51989/CD5 | |
| Sid Meier's Pirates! (Disc 1) | PC | 1.0 | Original | | 1013172 | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0 | Original | | 1015406 | |
| SimCity 2000 Special Edition | PC | 1.0 | Original | | MXE08301447D | |
| SimCity 3000 | PC | | EA Classics | | MXX08803493D | |
| SimCity 4 (Disc 1) | PC | 1.0.272.0 | EA Classics | | MXX08803894D | |
| SimCity 4 (Disc 2) | PC | 1.0.272.0 | EA Classics | | MXX08803894D2 | |
| The Simpsons: Hit & Run | PC | 1.0 | Covermount | | SUN016D | |
| The Sims 2 (Disc 1) | PC | 1.0.0.932 | Original | | MXX08004261D1 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.932 | Original | | MXX08004261D2 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.932 | Original | | MXX08004261D2 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | MXX08004261D3 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | MXX08004261D3 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.932 | Original | | MXX08004261D4 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.932 | Original | | MXX08004261D4 | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | MXD08006831D, MXX08006256D | |
| The Sims 2: Pets: Girl Talk Activity CD-ROM | PC | | Original | | | |
| The Sims 2: Sneak Preview CD | PC | | Original | | MXX08004115D3 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | MXX08004661D | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | MXX08004661D2 | |
| The Sims Life Stories | PC | 1.0 | Original | | MXX07705229D | |
| The Sims Medieval | PC | 1.0.286.00001 | Original, Limited Edition, Collector's Edition | | MXX09207555D, MXX09208224D, MXX09208231D | |
| The Sims (Documentation) | PC | | Original, The Sims: Collector's Edition | | MXE08903517D | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.90 | Original | | MXX08004115D, MXX08004115D/GER | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | 1.90 | Original | | MXX08004115D2, MXX08004115D2/GER | |
| The Sims: On Holiday (Expansion Pack) The Sims: Op Vakantie (Uitbreidingspakket) | PC | 1.5 | Original | | MXX08803801D | |
| Sno-Cross Extreme | PC | 1.00 | Bundle Version Tiny OEM | | KDGT4 | |
| Sonic & Knuckles Collection | PC | | Xplosiv | | XP-1859 EUROPEAN, XP-1891, XP-1891 EUROPEAN | |
| Sonic 3D: Flickies' Island | PC | | Xplosiv | | XP-1304 | |
| Sonic Mega Collection Plus | PC | | GSP | | 1654B | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Spore | PC | 1.0 | Original | | MXX09205658D | |
| Star Trek Pinball | PC | 1.00 | Covermount | | CD-C95-675-EME | |
| Star Trek: Legacy | PC | 1.0 | Original, Ubisoft eXclusive / Focus Essential | | ESS732, REF : 5005067 | |
| Star Trek: The Next Generation: Birth of the Federation | PC | 1.00 | Original | | 49141.DL | |
| Star Wars: Behind the Magic (Disc 1) | PC | 1.0 | Original | | 3000002.101.UK | |
| Star Wars: Behind the Magic (Disc 2) | PC | 1.0 | Original | | 3000002.102.UK | |
| Star Wars: Empire at War | PC | 1.00.36493 | Original | | 41137.101.EU | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.02a | Original | | 32573.101.3L | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Original | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Original | | 9521831 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | | Original | | 7101830 | |
| Star Wars: X-Wing vs. TIE Fighter (Master Game Disc) | PC | | Original | | 2081830 | |
| Star Wars: X-Wing vs. TIE Fighter (Multiplayer Disc) | PC | | Original | | 2081830 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 2.0.0 | Original | | 7091830 | |
| StarCraft | PC | 1.0 | Original | | S0012152 | |
| StarCraft II: Wings of Liberty | PC | 1.0.0.15405 | Original, Collector's Edition | | S2281209, S2286901 | |
| StarCraft: Brood War (Expansion Set) | PC | 1.04 | Original | | S0014249 | |
| Stolen | PC | 1.0 | Original | | | |
| Stonekeep | PC | 1.2 | Covermount | | CD-ICD-045-EME | |
| Streetwars: Constructor Underworld | PC | | Original | | strwapc52mult/a | |
| Stronghold FireFly Studios' Stronghold | PC | 1.1 | Original, TakeAdvantage | | | |
| Stronghold 2 (Disc 1) (Install) FireFly Studios' Stronghold 2 | PC | 1.0 | Original | | | |
| Stronghold 2 (Disc 2) (Play) FireFly Studios' Stronghold 2 | PC | 1.0 | Original | | | |
| Stronghold Legends | PC | 1.3.0.0 | Original, Special Edition | | | |
| Sudden Strike 3: Arms for Victory | PC | 1.0 | Original | | EI-2238 ML02 | |
| Sudden Strike II | PC | 2.0 | Original | | CDR8000/UK2 | |
| Super Solvers: Spellbound! | PC | 1.1 | Covermount, Softkey | | SLB844AB-CD | |
| Supreme Commander 2 | PC | 1.0 | Original | | SC2 PC/GEN/LAB | |
| Suzuki Alstare: Extreme Racing | PC | | Bundle Version Tiny OEM | | KDGT6 | |