| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Serious Sam: The First Encounter | PC | 1.00a | Software Pyramide |      | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Serious Sam: The First Encounter | PC | 1.05 | Gold Edition | | | |
| Serious Sam: The First Encounter | PC | 1.00a | Original, TakeAdvantage | | | |
| Serious Sam II | PC | | Original |  | | |
| Sensible Soccer: European Champions | CD32 | | Original | | SSI 1 | |
| Sensible Soccer 2006 | PC | 1.00.0000 | Original | | MSS1CDEU00 | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3P-EUR-B0 | |
| Semper Fi | PC | | Original | | | |
| Sega Worldwide Soccer PC | PC | | Original | | MK 85056-50 | |
| Sega Worldwide Soccer 97 | SS | 1.000 | Original | | MK81112-50 | |
| Sega Worldwide Soccer 97 | SS | 1.000 | Original | | MK81112-50 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.004 | Original | | MK81123-50 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.002 | Original | | MK81123-50 | |
| Sega Touring Car Championship | SS | 1.003 | Original | | MK81216-50 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | MK 85067-50 | |
| Sega Rally Championship PC | PC | 2.11 | Fair Game, Grabit | | FG-1282, GDL016 | |
| Sega Rally Championship PC | PC | 1.0 | Original | | MK 85048-50 | |
| Sega Rally Championship | SS | 1.000 | Original | | MK81207-50 | |
| Sega Rally Championship | SS | 1.000 | Original | | MK81207-50 | |
| Sega Rally 2 (Disc 2) (Play Disc)
Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-2 | |
| Sega Rally 2 (Disc 1) (Install Disc)
Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-1 | |
| Sega Rally 2
Sega Rally 2: Sega Rally Championship | DC | 1.001 | Original | | MK-51019-50 | |
 | Sega Rally 2 (Install Disc)
Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Play Disc)
Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Mega Drive Ultimate Collection | PS3 | 01.00 | Original | | BLES-00475 … | |
| Sega Mega Drive Ultimate Collection | XBOX360 | | Original, Classics | | SE-2085 | |
| Sega Mega Drive Collection | PSP | 1.01 | Original, PSP Essentials | | ULES-00556 | |
| Sega Mega Drive Classic Collection Volume 4 | PC | | Original |  | SEGA-PC121 | |
| Sega Mega Drive Classic Collection Volume 2 | PC | | Original | | SEGA-PC119 | |
| Sega Mega Drive Classic Collection Volume 1 | PC | | Original | | SEGA-PC118 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 2) | PC | 1.02 | Original | | | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge
The Monkey Island Bounty Pack: The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | 1.0 | LucasArts Classics: The Monkey Island Bounty Pack | | 3000012.101.UK | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| Secret Mission | CDI | | Original | | 810 0272 | |
| Secret Files: Tunguska | PC | 1.03 | Original, Xplosiv | | ECD008099M 00060722-01, XP-2221 3026412 | |
| Score International Baja 1000: World Championship Off Road Racing | PS2 | 1.00 | Original | | SLES-55295 | |
| Das Schwarze Auge: Drakensang: Phileassons Geheimnis | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Schmidt Interaktivspaß: Solitaire | PC | 1.0.0.0 | Original | | S0023093 | |
| Schmidt Interaktivspass: Doppelkopf | PC | 1.0.0.0 | Original | | S0022421 | |
 | Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| SBK-07: Superbike World Championship | PSP | 1.02 | Original | | ULES-00800 | |
| SBK 2011: FIM Superbike World Championship | PS3 | 01.00 | Original | | BLES-01226 | |
| SBK 09: Superbike World Championship | PS2 | 1.00 | Original | | SLES-55492 | |
 | SBK 08: Superbike World Championship | PC | | Covermount | | | |
| SBK 08: Superbike World Championship | PS3 | 01.01 | Original | | BLES-00368 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 011143 | |
| Santa Claus' Mice
Les Souris du Pere Noel | CDI | | Original | | 811 0012, 812 0023 | |
 | Sanitary Podzemelij
Санитары Подземелий | PC | | Original, 1C: Kollekciya igrushek |  | | |
| Sanitarium (Disc 3)
Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2)
Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1)
Шизариум | PC | 1.01 | Rerelease | | | |
| Sanitarium (Disc 2) | PC | 1.0 | Original | | CS090737 | |
| San Francisco Rush: Extreme Racing | PSX | | Original | | SLES-01208 | |
 | Samuraj Po-Xi
Super Zabawa | PC | | |  | | |
| Samurai Western | PS2 | 1.00 | Original | | SLES-53234 | |
| Samurai Warriors: Xtreme Legends | PS2 | 1.00 | Original | | SLES-53004 | |
| Samurai Warriors 2 | PS2 | 1.01 | Original | | SLES-54340 | |
| Samurai Warriors 2 | PC | | Original | | 04929UK | |
 | Samurai Warriors | PS2 | 1.00 | Original | | SLES-52555 | |
| Samurai Warriors | PS2 | 1.00 | Original | | SLES-52554 | |
| Samurai Warriors | PS2 | 1.00 | Original | | SLES-52553 | |
| Samurai Warriors | PS2 | 1.01 | Original | | SLES-52551 | |
| Samurai Shodown V | PS2 | 1.02 | Original | | SLES-53059 | |
| Samba de Amigo | WII | | Original |  | RVL-R3BP-EUR | |
| Sam & Max Hit the Road | PC | | Collezione CD-Rom by C.T.O. | | | |
| Sam & Max Hit the Road | PC | | LucasArts Classic | | 41117.101.IT | |
| Sam & Max Hit the Road | PC | | Softgold, Rerelease | | | |
| Sam & Max Hit the Road | PC | 2.0 | LucasArts Classic | | 41117.101.UK | |
| Sacred: La Leggenda dell'Arma Sacra (Disco 1) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| Sacred: La Leggenda dell'Arma Sacra (Disco 2) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| Saban's Power Rangers: Time Force | PC | | PC Fun Club, THQ Double Pack (Focus Essential) | | ESS589, PFC024/D | |
| Saban's Power Rangers: Time Force | PSX | | Original | | SLES-03730 … | |
| S³: Silent Storm: Sentinels | PC | | Gold Edition | | ROSILENTST0004lab, ROSILENTST0006lab3 | |
| S.L.A.I.: Steel Lancer Arena International
S.L.A.I.: Phantom Crash | PS2 | 0.11 | Beta Trial Code | | TLES-52940 | |
 | S.C.A.R.S. | PC | 1.1 | Budget | | MMICDR 5259 | |
