Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sfida al Tetris Magico | PSX | | Original | | SCES-02176 | |
| Shadow Man | PSX | | Original | | SLES-02281 | |
| Space Debris | PSX | | Original, Promo | | SCES-02432 | |
| Spice World | PSX | | Original | | SCES-01233 | |
| Star Wars: Dark Forces | PSX | | Original | | SLES-00640 | |
| Star Wars: Episodio I: Jedi Power Battles | PSX | | Original | | SLES-02610 | |
| Star Wars: Episodio I: La Minaccia Fantasma | PSX | | Original | | SLES-02037 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PSX | | Original | | SLES-00643 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PSX | | Original | | SLES-10643 | |
| Stuart Little 2 | PSX | | Original | | SCES-03848 | |
| Syphon Filter | PSX | | Original | | SCES-01913 | |
| Syphon Filter 2 (Disc 1) | PSX | | Original, Promo | | SCES-02288 | |
| Syphon Filter 2 (Disc 1) | PSX | Rev 1 | Platinum, 2 Giochi | | SCES-02288 … | |
| Syphon Filter 2 (Disc 2) | PSX | | Original, Promo | | SCES-12288 | |
| Syphon Filter 2 (Disc 2) | PSX | Rev 1 | Platinum, 2 Giochi | | SCES-12288 … | |
| Syphon Filter 3 | PSX | | Original, Platinum | | SCES-03700 … | |
| The Simpsons Skateboarding | PS2 | 1.01 | Original | | SLES-51360 | |
| Star Wars: Starfighter | PS2 | 1.00 | Original | | SLES-50168 | |
| Star Wars: Super Bombad Racing | PS2 | 1.01 | Original | | SLES-50207 | |
| Samurai Warriors | PS2 | 1.00 | Original | | SLES-52554 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51710 | |
| Il Signore degli Anelli: Le Due Torri | PS2 | 1.00 | Platinum | | SLES-51255 … | |
| SingStar '80s | PS2 | 1.01 | Original | | SCES-53605 | |
| SingStar Italian Party | PS2 | 1.00 | Original | | SCES-54869 | |
| SingStar top.it | PS2 | 1.00 | Original | | SCES-54077 | |
| Spider-Man 2 | PS2 | 1.00 | Original | | SLES-52447 | |
| Star Wars: Bounty Hunter | PS2 | 1.01 | Original | | SLES-50834 | |
| Star Wars: Jedi Starfighter | PS2 | 2.20 | Original | | SLES-50374 | |
| Summoner 2 | PS2 | 1.01 | Original | | SLES-51275 | |
| Sydney 2000 | DC | 1.000 | Original | | T-36808D-13 | |
| Sacred: La Leggenda dell'Arma Sacra (Disco 2) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| Sacred: La Leggenda dell'Arma Sacra (Disco 1) | PC | 1.6.66 | FX Interactive | | IT v.1.6.66 | |
| Sam & Max Hit the Road | PC | | LucasArts Classic | | 41117.101.IT | |
| Sam & Max Hit the Road | PC | | Collezione CD-Rom by C.T.O. | | | |
| Shade: L'Ira degli Angeli | PC | 1.01 | Original | | | |
| Shade: L'Ira degli Angeli | PC | 1.2 | EXA Games Premium, Covermount | | | |
| Sheep, Dog 'n' Wolf | PC | | Kellogg's | | | |
| Sierra Pro Pilot (Disc 1) (Scenario USA) | PC | 1.02 | Covermount | | S0013015 | |
| Sierra Pro Pilot (Disc 1) (Scenario Europa) | PC | 1.02 | Covermount | | S0013016 | |
| Sierra Pro Pilot (Disc 2) (Lezioni a Terra) | PC | | Covermount | | S0013017 | |
| Silver (Disc 1) | PC | | Replay Avventura | | SILVPCREI/A1 | |
| Silver (Disc 2) | PC | | Replay Avventura | | SILVPCREI/A2 | |
| Singles: Flirt Up Your Life! | PC | 1.2 | Original | | ECD000879K | |
| Space Ace | PC | | Jackson Libri | | | |
| SpellForce: The Order of Dawn (Disc 1) (Installa/Esegui CD) | PC | 1.52.61407 | Original | | ROSPELLFOR0027LAB1 | |
| SpellForce: The Order of Dawn (Disc 2) (Installa CD) | PC | 1.52.61407 | Original | | ROSPELLFOR0027LAB2 | |
| Star Wars: Behind the Magic: Vehicles Special Edition (Demo) | PC | 1.0 | Collezione CD-Rom by C.T.O. | | LUC633 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Collezione CD-Rom by C.T.O. | | 635930 | |
| Star Wars: Episodio I: La Minaccia Fantasma | PC | 1.0 | Original | | | |
| Star Wars: Episodio I: Racer | PC | 1.0 | Original | | | |
| Star Wars: Jedi Knight: Dark Forces II (Disco 1) | PC | | Collezione CD-Rom by C.T.O. | | LUC632 | |
| Star Wars: Jedi Knight: Dark Forces II (Disco 2) | PC | | Collezione CD-Rom by C.T.O. | | LUC632 | |
| Star Wars: La Sfida di Yoda | PC | | Covermount | | | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | 1.08 | Collezione CD-Rom by C.T.O. | | 3091831 | |
| Star Wars: Rebellion | PC | 1.01.00 | Collezione CD-Rom by C.T.O. | | LUC633 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | Collezione CD-Rom by C.T.O. | | 2061830 | |
| StarCraft | PC | 1.00 | BestSeller Series, Covermount | | | |
| StarCraft: Brood War (Expansion Set) | PC | 1.05 | BestSeller Series, Covermount | | S0014798 | |
| Starsky & Hutch | PC | | Covermount | | | |
| Steel Saviour | PC | 1.0.0.1 | Ludonic Red Label | | | |
| Stranger | PC | 1.0 | Original | | ECD632004D ITA | |
| Super Taxi Driver Corse pazze in città | PC | | Microforum | | | |
| Supreme Snowboarding | PC | 1.033 | Pringles | | VG-1012 | |
| Suzuki Alstare: Extreme Racing | PC | | Covermount | | | |
| SWAT 4 (Disc 1) | PC | 1.0.31973.0 | Covermount | | | |
| SWAT 4 (Disc 2) | PC | 1.0.31973.0 | Covermount | | | |
| Syberia II (Disc 1) | PC | 1.0 | Covermount | | | |
| Syberia II (Disc 2) | PC | 1.0 | Covermount | | | |
| SBK 08: Superbike World Championship | PC | | Covermount | | | |
| The Suffering | PC | 1.1.0.1 | Covermount | | | |
| Silverfall: Edizione Oro | PC | 1.00 | Original | | IT V1.00 P - DVD | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Strip Poker Live | CDI | | Original | | IM99002 | |