Region | Title | System | Version | Edition | Languages | Serial | Status |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy | PS2 | 1.00 | Review Build | | SLUS-20762 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Bass Fishing 2 | DC | 1.080 | Original | | 51166 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega Marine Fishing | DC | 1.001 | Original | | 51096 | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Rally Championship Plus Netlink Edition | SS | 1.001 | Net Link Game Pack | | 81215, 81608 | |
| Sega Rally Revo | PSP | 1.00 | Original | | ULUS-10311 | |
| Sega Screams Volume 2 | SS | 2.000 | Not for Resale | | 81077 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Sega Soccer Slam | PS2 | 1.00 | Original | | SLUS-20509 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| Sengoku Rance 戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Sentient | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Serious Sam | XBOX | | Original | | TT-004 | |
| Serious Sam: Next Encounter | GC | Rev 1 | Original | | DL-DOL-G3BE-USA | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Preschool (Disc 1) (Elmo's Preschool) | PC | 3.1 | Original | | P/N 379663-CD1 | |
| Sesame Street: Elmo's Preschool (Disc 2) (Search & Learn Adventures) | PC | 3.1 | Original | | P/N 379663-CD2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: My Baby & Me (Disc 1) (Baby & Me) | PC | 1.0 | Original | | SSY744AE-CD1 | |
| Sesame Street: My Baby & Me (Disc 2) (Sesame Street Greatest Hits Sampler) | PC | 1.0 | Original | | SSY744AE-CD2 | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Seventh Cross Evolution | DC | 1.000 | Original | | T-41301N | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Original | | T-6201 | |
| Shadoan | PC | | Interactive Preview | | | |
| Shadow Company: Left for Dead (Digital Press Kit) | PC | | Press Kit | | 5051895 | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shadow Force: Razor Unit | PC | | Special Forces Pack | | SFRU-0414 | |
| Shadow Man | PC | | Original | | | |
| Shadow Man | DC | 1.010 | Original | | T-8106N | |
| Shadow of Rome | PS2 | 1.00 | Demo | | SLUS 29139 | |
| Shadow of the Beast | PCE | | Original | | TGXCD1018 | |
| Shadow of the Beast II | MCD | | Original | | T-113045 | |
| Shadow Ops: Red Mercury | XBOX | | Original | | IG-037 | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| ShadowGate Classic | PPC | 1.0.0.4 | Original | | 5053626 | |
| Shadowgrounds (Disc 1) | PC | 1.01 | Original | | 000046-CD1 | |
| Shadowgrounds (Disc 2) | PC | 1.01 | Original | | 000046-CD2 | |
| Shadowlands | PC | | Megapak 2 | | | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shadows of Cairn | PC | 1.0.022 | Rerelease | | ROM-53337 | |
| Shakii the Wolf | PC | | Original | | | |
| Shanghai Double Pack | PC | | Original | | | |
| Shanghai II: Dragon's Eye | PC | 1.05 | 2 for 1 | | CDD-3044-101-U3 | |
| Shanghai: Great Moments | PC | 2.00 | Bundle Version Canon OEM | | | |
| Shannara | PC | 1.0 | Rerelease | | 7-81055-33802-6 | |
| Shaolin | PSX | | Preview | | | |
| Shape Shifter | PC | | Original | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.23 | Unlicensed | | | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Shaun Palmer's Pro Snowboarder | PS2 | 1.00 | Original | | SLUS-20199 | |
| Shaun White Snowboarding | XBOX360 | | Target Limited Edition | | US-2078 | |
| Shaun White Snowboarding | PS2 | 1.01 | Original | | SLUS 21853 | |
| Shaun White Snowboarding | PSP | 1.01 | Original | | ULUS 10399 | |
| ShellShock: Nam '67 | PC | 1.00 | Original | | MSHOCPUS01 | |
| ShellShock: Nam '67 | PS2 | 2.00 | Original | | SLUS-20828 | |
| Shepherd's Crossing | PSP | 1.00 | Original | | ULUS-10499 | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Sherlock Holmes: Consulting Detective: Vol. I | VIS | | Original | | 25-6183 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Rerelease | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 5.1 | 5 ft. 10 PAK Vol. 2 | | CD 7012 SPI | |
| Sherlock Holmes: Consulting Detective: Vol. II | VIS | | Original | | 25-6184 | |
| Sherlock Holmes: Consulting Detective: Vol. II | PCE | | Original | | TGXCD1039 | |
| Sherlock Holmes: Consulting Detective: Vol. III | PC | 4 | Original | | CDRM1061930 | |
| Sherlock Holmes: Nemesis (Disc 1) | PC | 1.00.0777 | Original | | PCO589CD1, SNY 1.0 | |
| Sherlock Holmes: Nemesis (Disc 2) | PC | 1.00.0777 | Original | | PCO589CD2, SNY 1.0 | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| Shimano Xtreme Fishing | WII | | Original | | RVL-R39E-USA-B0 | |
| Shin Megami Tensei: Devil Summoner: Raidou Kuzunoha vs. the Soulless Army | PS2 | 1.00 | Trade Demo | | SLUS-28064 | |
| Shin Megami Tensei: Digital Devil Saga | PS2 | 1.00 | Trade Demo | | SLUS-28049 | |
| Shin Megami Tensei: Digital Devil Saga 2 | PS2 | 1.00 | Trade Demo | | SLUS-28052 | |
| Shin Megami Tensei: Nocturne | PS2 | 1.00 | Trade Demo | | SLUS-28045 | |
| Shin Megami Tensei: Persona | PSP | 1.00 | Original | | ULUS-10432 | |
| Shin Megami Tensei: Persona 3 | PS2 | 1.00 | Trade Demo | | SLUS-28067 | |
| Shin Megami Tensei: Persona 3 FES | PS2 | 1.00 | Trade Demo | | SLUS-28068 | |
| Shin Megami Tensei: Persona 3 Portable | PSP | 1.00 | Trade Demo | | ULUS-80022 | |
| Shin Megami Tensei: Persona 4 | PS2 | 1.00 | Trade Demo | | SLUS-28069 | |
| Shining Force EXA | PS2 | 1.00 | Original | | SLUS-21567 | |
| Shining Force III | SS | 1.000 | Beta | | | |
| Shining Wisdom | SS | 1.000 | Beta | | | |
| Shining Wisdom | SS | 1.000 | Preview | | | |
| Shinobi | PS2 | 1.00 | Trade Demo | | SLUS-28016 | |
| Shinobi Legions | SS | 1.000 | Original | | T-2301H | |
| The Ship | PC | | Original | | | |
| Shiren the Wanderer | WII | | Original | | RVL-RFSE-USA-B0 | |
| Shivers Two: Harvest of Souls | PC | 1.0 | Demo | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.00 | | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shockwave Assault | SS | 1.000 | Original | | T-5005H | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shogo: Mobile Armor Division | PC | 2.2 | Bundle Version Creative Labs OEM | | 1713310341 | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | 798727 | |
| Shogun: Total War: The Mongol Invasion Shōgun: Total War: The Mongol Invasion | PC | 1.00 | Original | | 1430907 | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Original | | RVL-RIPE-USA | |
| Shonen Jump's One Piece: Grand Adventure | GC | | Original | | DL-DOL-GOQE-USA | |
| Shonen Jump's One Piece: Grand Battle | PS2 | 1.00 | Demo | | SLUS 29159 | |
| Shonen Jump's One Piece: Pirates' Carnival | GC | | Original | | DL-DOL-GIPE-USA | |
| Shonen Jump's One Piece: Pirates' Carnival | PS2 | 1.00 | Original | | SLUS-21364 | |
| Shonen Jump's Shaman King: Power of Spirit | PS2 | 1.00 | Original | | SLUS-20953 | |
| Showdown: Legends of Wrestling | PS2 | 1.01 | Original | | SLUS-21017 | |
| ShowMaster | CDI | 1.0 | Demo | | | |
| Shrak Shrak for Quake | PC | 2.0 | Rerelease | | | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shrek 2 (Final Press Kit) | PC | | Press Kit | | | |
| Shrek 2 | PC | | | | 32585.101.US | |
| Shrek 2: Team Action | PC | 1.0 | Original | | 32789.101.US | |
| Shrek Extra Large | GC | | Original | | DL-DOL-GS9E-USA | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek Super Party | GC | | Original | | DL-DOL-GSYE-USA | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Sid Meier's Civilization Chronicles (Disc 1) | PC | | Original | | 31074-1.1 | |
| Sid Meier's Civilization Chronicles (Disc 2) | PC | | Original | | 31074-1.2 | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition (Rerelease) | | | |
| Sid Meier's Civilization III | PC | 1.29f | Scholastic | | P/N CDR9640733 | |
| Sid Meier's Civilization III Complete | MAC | 1.22 | Original | | 11180-1DDA | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | Original | | 25766CD2 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | Original | | 25766CD3 | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Sid Meier's Pirates! (Disc 1) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 2) | PC | | Rerelease | | | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Siege | PC | 1.2 | | | | |
| Sierra Press Kit | PC | | Press Kit | | | |
| Sierra Pro Pilot (Disc 1) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot (Disc 2) | PC | 1.0 | Original | | | |
| Sierra's School House: English (Disc 1) | PC | | Original | | | |
| Sierra's School House: English (Disc 2) | PC | | | | | |
| Sierra's School House: Science (Disc 1) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Science (Disc 2) | PC | | Original | | 831614230/S161155 | |
| Silent Heroes: Elite Troops of WWII | PC | 1.0.29.0 | Original | | | |
| Silent Hill: Shattered Memories | PSP | 1.00 | Original | | ULUS-10450 | |
| Silent Hunter | PC | 1.0 | Rerelease | | WWD144AE-CD | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Original | | 2211110-590004 | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Ultimate Wargame Collection Volume 2: World War II | | 379280-CD2 | |
| Silent Hunter: Wolves of the Pacific | PC | 1.2.0.0 | Original | | 683438-DVD1 | |
| Silent Line: Armored Core | PS2 | 1.00 | Original | | SLUS-20644 | |
| Silent Scope | DC | 1.000 | Original | | T-9507N | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Silkolene Honda Motocross GP | PC | 1.0 | Original | | 13030 | |
| A Silly Noisy House | MAC | | Original | | CDAC 014500 | |
| Silver | DC | 1.001 | Original | | T-15108N | |
| Silver (Disc 1) | PC | 1.08C | | | | |
| Silver (Disc 2) | PC | 1.08C | | | | |
| SimAnt | PC | | Scholastic | | 5710346C SP2 | |
| SimCity (Preview Disc) | PC | | Target | | 7298103301 | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Megapak 8 | | 01130-059-0601 | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| SimCity 3000 | PC | | Domino's Pizza / Easter Seals | | | |
| SimCity 3000 | PC | | Linux | | | |
| SimCity 3000 | PC | | Pre-Order Bonus | | 4083407 | |
| SimCity 3000 | PC | | Scholastic | | 1500107 | |
| SimCity 3000 | MAC | 1.0.557 | Original | | 1500607 | |
| SimCity 3000 | PC | 1.2.673.0 | Rerelease | | 1500117 | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| SimCity 3000 Unlimited | PC | 2.0.949 | Scholastic | | 1500907 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | | Original | | 1474007 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | | SimCity Box | | 1907327 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | SimCity Box | | 1907327 | |
| SimCity 4: Rush Hour | PC | 1.0 | Original | | 1472207 | |
| SimCity Classic | PC | | Collector's Series | | 0002-000-0612-A | |
| SimCity Enhanced CD-ROM | PC | | Rerelease | | CD-ICD-204-0 | |
| SimCity Enhanced CD-ROM | MAC | | MacPlay | | CD-MCR-041-0 | |
| SimCity Enhanced CD-ROM | PC | | Original | | CD-ICD-041-0 | |
| SimCity Enhanced CD-ROM | PC | 1.0 | Rerelease | | CD-ICD-508-0 | |
| SimClassics: 3 in 1 Pack | PC | | Original | | 0543-000-0601-A | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| SimCoaster | PC | | Scholastic | | 14257?7 | |
| SimCoaster | PC | | Rerelease | | 14257?7 | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| SimLife SimLife: The Genetic Playground | PC | | Rerelease | | | |
| Simon the Sorcerer | PC | 1.00 | Original | | | |
| The Simpsons Game | XBOX360 | | Original | | EA-2057 | |
| The Simpsons Game | PSP | 1.00 | Original | | ULUS-10295 | |
| The Simpsons: Road Rage | PS2 | 1.00 | Beta | | SLUS-20305 | |
| The Sims 2 | MAC | | Rerelease | | 10880-1DDA | |
| The Sims 2 | PSP | 1.00 | Original | | ULUS-10031 | |
| The Sims 2 | PS2 | 1.00 | Beta | | SLUS-21066 | |
| The Sims 2 | PS2 | 1.00 | Beta | | SLUS-21265 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1005 | Rerelease | | 1472647 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.1005 | Rerelease | | 1472657 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.1005 | Rerelease | | 1472667 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.1005 | Rerelease | | 1472677 | |
| The Sims 2: Happy Holiday Stuff | PC | | Original | | 1527707 | |
| The Sims 2: Insider Preview CD | PC | | Original | | 1625207 | |
| The Sims 2: Nightlife (Expansion Pack) | MAC | | Original | | 11330-1DDA | |
| The Sims 2: Open For Business (Expansion Pack) | MAC | | Original | | 11390-1DDA | |
| The Sims 2: Pets | PSP | 1.00 | Original | | ULUS 10130 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: University (Expansion Pack) | MAC | | Original | | 11110-1DDA | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 3: University Life (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 1980803301 | |
| The Sims Online (Disc 1) | PC | 1.0 | Charter Edition | | 1461517 | |
| The Sims Online (Disc 2) | PC | 1.0 | Charter Edition | | 1461527 | |
| The Sims Online: Sampler Disc | PC | | Original | | 4025407 | |
| The Sims Strategy Guide and SimFan Pack | PC | | Pre-Order Bonus | | 1414407 | |
| The Sims Mandrake Linux Gaming Edition (The Sims for Linux) | PC | | Linux (Mandrake Linux Gaming Edition) | | | |
| The Sims | MAC | | | | | |
| The Sims | MAC | | | | | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | 1457637 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Scholastic | | 1459517 | |
| The Sims: Vacation (Expansion Pack) | MAC | | Original | | | |
| SimTheme Park Sim Theme Park | PC | | Scholastic | | 1403307 | |
| SimTheme Park Sim Theme Park | PC | | Original | | 1403307 | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-B | |
| SimTown | PC | | The Kids Collection | | 1258607 | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| SiN | PC | | Linux | | | |
| SiN | PC | 1.01 | Rerelease | | 6236 01 | |
| SiN | PC | 1.01 | Original | | 1000076.101.US | |
| SiN Gold | MAC | | MacPlay | | | |
| SiN Gold | MAC | 1.1.1 | Original | | | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.US | |
| Sinbad: Legend of the Seven Seas | PC | 1.0 | Original | | Part # 24755CD | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sing-Along Kids: Vol. 2 | PC | | | | | |
| SingStar Amped | PS2 | 1.00 | Original | | SCUS-97612 | |
| SingStar Queen | PS2 | 1.00 | Original | | SCUS-97643 | |
| SingStar Rocks! | PS2 | 1.00 | Original | | SCUS-97571 | |
| Sinistar: Unleashed | PC | | Original | | | |
| Sins of a Solar Empire | PC | | Rerelease | | | |
| Sins of a Solar Empire | PC | 1.165 | Game of the Year Edition | | | |
| Sins of a Solar Empire: Trinity | PC | | | | | |
| Sins of a Solar Empire: Trinity | PC | | Rerelease | | | |
| Siren | PS2 | 1.00 | Demo | | SCUS 97398 | |
| Skeleton Warriors | SS | 1.001 | Original | | T-13204 H | |
| Ski-Doo Snow X Racing | PS2 | 1.00 | Original | | SLUS-21591 | |
| Skies of Arcadia (Disc 1) | DC | 1.002 | Original | | 51052 | |
| Skies of Arcadia (Disc 2) | DC | 1.002 | Original | | 51052 | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Skunny Kart Combo | PC | | Original | | | |
| SkyGunner | PS2 | 1.00 | Demo | | SLUS 29020 | |
| SkyMaze X3D SkyMaze | PC | | X3D | | | |
| SkyTrip America SkyTrip America: An Incredible Ride Through U.S. History! | PC | 1.0 | | | | |
| Slam 'n Jam '95 | 3DO | | Beta (CD-R) | | | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Sega CD 32X | | T16204F | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 2) (Juice) | MCD | | Sega CD 32X | | T16204F | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Sega CD 32X | | T16204F | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Original | | T162035 | |
| Slam City with Scottie Pippen (Disc 4) (Smash) | MCD | | Sega CD 32X | | T16204F | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | | Original | | WTY744AE-CD | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | 1.01 | Rerelease | | TYN744BE-CD | |
| Slater & Charlie Go Camping | PC | 1.000 | SierraOriginals | | | |
| Slave Pageant (Game Disc) | PC | | Original | | GC-020 | |
| Slave Pageant (Install Disc) | PC | | Original | | GC-020 | |
| Slave Zero | DC | 1.001 | Original | | T-15106N | |
| Slave Zero | DC | 1.002 | Original | | T-15106N | |
| Sled Storm | PS2 | 1.00 | Original | | SLUS-20363 | |
| Sleepwalker | PC | | Megapak 2 | | 42631-911SWC | |
| Slingo | PC | | Oregon Lottery | | | |
| Slingo | PC | | Original | | 99310 | |
| Slingo 2-Pack | PC | | Original | | | |
| Slingo Quest | PC | 0.0.0.104 | Original | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Slingo: Wild 7's | PC | | Oregon Lottery | | | |
| Sliver (Disc 1) | CDI | | Original | | 310690309-2 | |
| Sliver (Disc 2) | CDI | | Original | | 310690309-2 | |
| Slot City Jackpot Games (120 Slot Machines) | PC | | Jackpot Games | | CD-4700 | |
| Slot City 2 Plus Video Poker | PC | 1.0 | Original | | 7200-CD1 | |
| Slots 100 | PC | | Cosmi | | CDR712D1, SJ 062001 | |
| Slots Adventure: War for Olympus | PC | 1.0 | Original | | | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Slots Featuring WMS Gaming | PC | 1.0.3 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.1 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.2 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Sly 3: Honor Among Thieves | PS2 | 1.00 | Demo | | SCUS 97484 | |
| Small Soldiers | PSX | | Preview | | | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Smart Games: Challenge 1 | PC | | Original | | P/N:DSGC1CD0001 | |
| Smart Series Presents: Jaja's Adventure | WII | | Original | | RVL-R67E-USA-B0 | |
| Smart Steps: Kindergarten | PC | | Rerelease | | P/N: LDSMASTKIJ | |
| Smart Steps: Kindergarten | PC | 1.0 | Original | | | |
| SmartKids Challenge One | VIS | | Original | | 25-6176 | |
| Smash Court Tennis 3 | PSP | 1.00 | Original | | ULUS-10269 | |
| Smash Court Tennis: Pro Tournament | PS2 | 1.00 | Original | | SLUS-20286 | |
| Smashing Drive | GC | | Original | | DL-DOL-GSDE-USA | |
| The Smelly Mystery | PC | 1.0 | Original | | 04-12328CD | |
| Smuggler's Run: Warzones | GC | | Original | | DL-DOL-GSRE-USA | |
| The Smurfs: Dance Party | WII | | Toys R Us | | RVL-SDUX-USA-B0 | |
| Snap Dragon | PC | 1.0 | Original | | | |
| Snap! 3D Bowling | PC | | Original | | | |
| Snap! 400 Word Searches | PC | | Original | | CS-296 | |
| Snap! Pinball | PC | | Original | | | |
| Snap! Pool Perfect Pool | PC | 1.1 | Original | | | |
| Snap! Subtraction: Ages 5-8 | PC | | Original | | | |
| Sniper Elite | PC | | Original | | 40009 | |
| Sniper Elite | PS2 | 1.02 | Original | | SLUS-21231 | |
| Sniper Elite V2 | XBOX360 | | Original | | FO-2024 | |
| Sniper: Ghost Warrior | PC | | Original | | L0001US | |
| SnoCross Championship Racing Sno-Cross Championship Racing | DC | 1.000 | Original | | T-40207N | |
| Snoopy vs. the Red Baron | PC | | Original | | | |
| Snoopy vs. the Red Baron | PSP | 1.00 | Original | | ULUS-10189 | |
| Snoopy's Campfire Stories | PC | | Original | | | |
| Snow Drop | PC | | Original | | P-002 | |
| Snow Sakura | PC | | Original | | GC030 | |
| Snowboard Park Tycoon | PC | | | | 30983.101.US | |
| SnowJob Starring Tracy Scoggins (Disc 1) | 3DO | | Original | | | |
| SnowJob Starring Tracy Scoggins (Disc 2) | 3DO | | Original | | | |
| So Who's Dr. Rabbit? | PC | | Original | | | |
| So You Wanna Be a Redneck | PC | | Original | | | |
| Soccer Mania | PS2 | 1.00 | Original | | SLUS-20456 | |
| Socket Low Power SDIO WLAN | PPC | Release 142 D | Original | | P/N 6210-00142 D | |
| SocketScan | PALM | Release 108K | Original | | P/N 6210-00108 K | |
| SOCOM II: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97368 | |
| SOCOM: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97205 | |
| SOCOM: U.S. Navy SEALs | PS2 | 1.00 | Public Beta v1.0 | | SCUS 97859 | |
| SOCOM: U.S. Navy SEALs | PS2 | 2.01 | Original | | SCUS-97134 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo | PSP | 1.00 | Public Beta v1.0 | | UCUS 98637 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 2 | PSP | 1.00 | Best Buy Demo | | UCUS 98692 | |
| Software & Document: Master CD for Video Family | PC | 1.20 | Bundle Version Jaton OEM | | | |
| The Software Toolworks CD Deluxe Pack: Version 2 | PC | | Bundle Version Packard Bell OEM | | 2192611-590001 170122 | |
| The Software Toolworks CD Game Pack | PC | | Original | | | |
| The Software Toolworks Presents: Maniac Sports | MAC | | Original | | 2200820-590001 / I034100 | |
| The Software Toolworks' Star Wars Chess | MCD | | Original | | T-87035 | |
| The Software Toolworks' Star Wars Chess | PC | 1.00 | Bundle Version OEM | | 13-004-060 | |
| Sol-Feace | MCD | RE | Bundled with Sega CD | | 4130 | |
| Soldier of Fortune | DC | 1.001 | Original | | T-40212N | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| Soldiers at War | PC | | Preview | | | |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | PC | | Rerelease | | | |
| Solid State Pinball: Crystal Caliburn | PC | | Rerelease | | 517-05-232 | |
| Solitaire Antics Ultimate | PC | 1.0.3L | Original | | | |
| Solitaire Deluxe | PC | 2.00 | Original | | CD-C95-080-0 | |
| Solitaire Master | PC | | Original | | 20-1280-10 | |
| Solitaire Master 2 | PC | 2.0 | Original | | 11-2806-10 | |
| Solitaire Master 4 | PC | 1.0 | Original | | 02-8156-10 | |
| Solitaire Master 5 | PC | 1.0 | Original | | 02-2153-10 | |
| Solitaire: 50 Complete Games! | PC | 2.0 | Rerelease | | 10-0990-10 | |
| Sonic & Garfield Pack | PC | | Original | | 85090 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sonic 3D Blast | PC | 1.0 | Twin Pack | | 6822 01 | |
| Sonic 3D Blast | PC | 1.0 | Expert Software | | 6822 01 | |
| Sonic Adventure | DC | 1.000 | Trial Version for E3 | | HDR-0001 | |
| Sonic and the Secret Rings Comic Book DVD from Archie Comics | PC | | | | | |
| Sonic CD | MCD | | Original | | | |
| Sonic CD | MCD | | Original | | 4407 | |
| Sonic CD | PC | | Expert Software | | 6805 01 | |
| Sonic CD | PC | 1.0 | Sonic Action 4 Pack | | | |
| Sonic CD | MCD | 1.15 | Beta | | | |
| Sonic MegaMix | MCD | | Unlicensed | | | |
| Sonic R | PC | | Original | | 85076 | |
| Sonic Shuffle | DC | 1.000 | Original | | 51060 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Sorority House: An Interactive Game of Hide and Peek | PC | 1.0 | Original | | | |
| Sorry / Boggle / Yahtzee: Triple Pack of Fun | PC | | Original | | Part # 26023CD | |
| Sorry! | PC | | Original | | 99040 | |
| Sorting Adventures: Interactive Activities | PC | | Original | | AAP899, PP463 | |
| Soul Fighter | DC | 1.000 | Original | | T-41401N | |
| Soulbringer (Disc 1) | PC | | Original | | CD-C95-1077-0 | |
| SoulStar | MCD | | Original | | T-115035 | |
| Soundtrack1: The Definitive Xbox Compilation (Disc 2) | PC | | Original | | 314 584 098 2 | |
| South Park Rally | DC | 1.001 | Original | | T-8116N | |
| Soviet Strike | PSX | Rev 1 | Greatest Hits | | SLUS-00061 | |
| Space Ace | PC | | Original | | | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | MCD | | Demo | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| Space Bucks | PC | | Original | | | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Colony | PC | | Original | | | |
| Space Dudes | PC | | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Space Invaders | PSX | | Review | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |