Region | Title | System | Version | Edition | Languages | Serial | Status |
| Solitaire Games | PC | | GSP | | 92534-A | |
| Solitaire Mania | MAC | | Original | | PART NO. 05SMM-01 | |
| Solitaire Master | PC | | Original | | 20-1280-10 | |
| Sonic & Garfield Pack | PC | | Original | | 85090 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sonic 3D Blast | PC | | Expert Software | | 6822 01 | |
| Sonic and the Secret Rings Comic Book DVD from Archie Comics | PC | | | | | |
| Sonic CD | MCD | | Original | | | |
| Sonic CD | MCD | | Original | | 4407 | |
| Sonic CD | PC | | Expert Software | | 6805 01 | |
| Sonic Heroes | XBOX | | Platinum Family Hits | | SE-043 | |
| Sonic MegaMix | MCD | | Unlicensed | | | |
| Sonic R | PC | | Original | | 85076 | |
| Sonic Riders | XBOX | | Original | | SE-135 | |
| Sonic Unleashed | XBOX360 | | Original, Platinum Hits | | SE-2066 | |
| Sonic's Ultimate Genesis Collection | XBOX360 | | Platinum Hits | | SE-2064 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Sony E3 2004: Press Information | PC | | Press Kit | | | |
| Sony PlayStation 2: SCEA Santa Monica Studios: 2004 Press Information: Press Print | PC | | Press Kit | | | |
| Sorry / Boggle / Yahtzee: Triple Pack of Fun | PC | | Original | | Part # 26023CD | |
| Sorry! | PC | | Original | | 99040 | |
| Sorting Adventures: Interactive Activities | PC | | Original | | AAP899, PP463 | |
| Soulbringer (Disc 1) | PC | | Original | | CD-C95-1077-0 | |
| Soulcalibur II | XBOX | | Demo | | NM-003 | |
| SoulStar | MCD | | Original | | T-115035 | |
| Sounds Best on Sound Blaster Every Game Sounds Best on Sound Blaster: 24-bit Advanced HD | PC | | | | | |
| Soundtrack1: The Definitive Xbox Compilation (Disc 2) | PC | | Original | | 314 584 098 2 | |
| South Park: The Fractured But Whole (Disc 1) | PC | | Gold Edition | | UBP60802045-DISC1 | |
| South Park: The Fractured But Whole (Disc 2) | PC | | Gold Edition | | UBP60802045-DISC2 | |
| South Park: The Fractured But Whole (Disc 3) | PC | | Gold Edition | | UBP60802045-DISC3 | |
| South Park: The Stick of Truth | PC | | Original | | 689058-DVD | |
| SouthPeak Interactive E3 2000 Electronic Press Kit | PC | | Press Kit | | | |
| Space Ace | PC | | Original | | | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | MCD | | Demo | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| Space Bucks | PC | | Original | | | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Camp | WII | | Original | | RVL-RIYE-USA | |
| Space Chimps | XBOX360 | | Original | | BT-2004 Version: 1. | |
| Space Chimps | WII | | Original | | RVL-RP9E-USA | |
| Space Colony | PC | | Original | | | |
| Space Dudes | PC | | Original | | | |
| Space Engineers | PC | | Limited Edition | | | |
| Space Invaders | PSX | | Review | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Sirens | PC | | Original | | SKU: UN017 | |
| Space Station Tycoon | WII | | Prototype | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| Spartan: Total Warrior | XBOX | | Original | | SE-139 | |
| Spartan: Total Warrior | XBOX | | Review | | | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAE-USA | |
| Spawn: Armageddon | XBOX | | Original | | NM-012 | |
| Spawn: Armageddon | GC | | Original | | DL-DOL-GPWE-USA | |
| Spec Ops: Ranger Team Bravo | PC | | Original | | CD-RC010 | |
| Spec Ops: Rangers Lead the Way | PC | | Demo | | CD-RC008 | |
| Spec Ops: The Line | PC | | Premium Edition | | 41152-1 | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Spectral Force 3 | XBOX360 | | Original | | AT-2003 | |
| Spectre VR CD | MAC | | Original | | | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Speed | WII | | Original | | RVL-SPEE-USA-B0 | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Freaks (Misc Artwork: PC-CD 2nd July '99) | PC | | Press Kit | | | |
| Speed Kings | XBOX | | Original | | AC-011 | |
| Speed Kings | GC | | Original | | DL-DOL-GDCE-USA | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Speed Zone | WII | | Original | | RVL-RZSE-USA-B0 | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Sphinx and the Cursed Mummy | XBOX | | Original | | TQ-035 | |
| Spider-Man | PC | | Demo | | | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| Spider-Man 2 | PC | | Demo | | | |
| Spider-Man 3 | PC | | Original | | 33121.101.US | |
| Spider-Man: Friend or Foe | XBOX360 | | Original | | AV-2042 | |
| Spider-Man: Friend or Foe | WII | | Original | | RVL-RFOE-USA | |
| Spider-Man: Friend or Foe | PC | | Original | | 33167.101.US | |
| Spider-Man: Shattered Dimensions | PC | | Original | | 33355101US | |
| Spider-Man: Web of Shadows | XBOX360 | | Original | | AV-2069 | |
| The Spiderwick Chronicles | XBOX360 | | Bundled with Audiobook | | VU-2022 | |
| The Spiderwick Chronicles | WII | | Original | | RVL-R48E-USA | |
| Spikeout: Battle Street | XBOX | | Original | | SE-041 | |
| Spine Sense: The Interactive Back Protection Program | CDI | | Original | | | |
| Spirits & Spells | GC | | Original | | DL-DOL-G2PE-USA | |
| Splashdown | XBOX | | Original | | IG-027 | |
| Splatt! | PC | | Original | | | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Wurx 1 | PC | | Original | | CDO226 | |
| Sports: Football | CD32 | | | | | |
| SPRay | WII | | Beta | | | |
| SPRay | WII | | Original | | RVL-RYIE-USA | |
| Spring 2012 Refresh Standard: PS3 IDU 4.11 | PS3 | | Kiosk Demo | | | |
| Spring 2013: Standard IDU 4.31 | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2010: 3.21 IDU Update (E-M) | PS3 | | Kiosk Demo | | | |
| Spring Refresh 2011 3.60 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Spy Fox in "Cheese Chase" | PC | | Original | | | |
| Spy Fox in "Dry Cereal" | PC | | Rerelease | | Part # 0001407 | |
| Spy Fox in "Dry Cereal" | PC | | Demo | | | |
| Spy Fox: "Operation Ozone" | PC | | Original | | | |
| Spy Fox: "Operation Ozone" | PC | | Rerelease | | pvaol008spyo | |
| Spy Games: Elevator Mission | WII | | Original | | RVL-RECE-USA-B0 | |
| Spy Kids Learning Adventures: The Candy Conspiracy | PC | | Original | | 03962 | |
| Spy Kids Learning Adventures: The Nightmare Machine | PC | | Original | | 03963 | |
| Spy vs. Spy | XBOX | | Original | | TT-124 | |
| Spyborgs | WII | | Beta | | | |
| Spycraft: The Great Game | PC | | Enhanced DVD-ROM Edition | | | |
| Spycraft: The Great Game (Disc 1) | MAC | | Original | | CDM-3110-101-US | |
| Spycraft: The Great Game (Disc 1) | PC | | Original | | CDD-3110-101-U3 | |
| Spycraft: The Great Game (Disc 2) | MAC | | Original | | CDM-3110-102-U3 | |
| Spycraft: The Great Game (Disc 3) | MAC | | Original | | CDM-3110-103-U3 | |
| Spycraft: The Great Game (Disc 3) | PC | | Original | | CDD-3110-103-U3 | |
| SpyHunter | GC | | Original | | DL-DOL-GSHE-USA | |
| SpyHunter 2 | XBOX | | Original | | MW-027 | |
| SpyHunter: Nowhere to Run | XBOX | | Original | | MW-055 | |
| Spyro the Dragon | PSX | | SCEE Preview | | | |
| Spyro the Dragon | PSX | | SCEA Preview | | | |
| Square Enix E3 2004 Media CD | PC | | Press Kit | | | |
| SquareSoft: E3 2001 Media CD | PC | | Press Kit | | | |
| Squeeballs Party | WII | | Original | | RVL-R6YE-USA-B0 | |
| SRS: Street Racing Syndicate | XBOX | | Original | | NM-019 | |
| SRS: Street Racing Syndicate | GC | | Original | | DL-DOL-GCSE-USA | |
| SSN-21 Seawolf Sea Wolf | PC | | Bundle Version Creative Labs OEM | | | |
| SSN-21 Seawolf | PC | | CD-ROM Classics: Gold Edition | | 5735 | |
| SSX 3 | XBOX | | Original | | EA-060 | |
| SSX 3 | GC | | Original | | DL-DOL-GXBE-USA | |
| SSX Blur | WII | | Beta | | | |
| SSX Blur | WII | | Original | | RVL-RSXE-USA | |
| SSX on Tour | XBOX | | Original | | EA-130 | |
| SSX Tricky | XBOX | | Platinum Hits | | EA-004 | |
| Stacked with Daniel Negreanu | XBOX | | Original | | MM-001 | |
| The Stanley Parable (Installation Disc) | PC | | IndieBox | | | |
| Star Control 3 | PC | | CD-ROM Classics | | 5991 | |
| Star Control 3 | PC | | Total War | | | |
| Star Defender III | PC | | Original | | CD001697 | |
| Star Fighter | MAC | | | | 03239-001 | |
| Star Fox Adventures: Game Preview CD | PC | | Promo | | | |
| Star Rangers | PC | | Original | | | |
| Star Reach | PC | | Original | | CD-ICD-050-0 | |
| Star Trek | XBOX360 | | Original | | NM-2139 | |
| Star Trek Pinball | PC | | Bundle Version OEM | | CD-C95-675-UNU | |
| Star Trek VI: The Undiscovered Country (Disc 1) | CDI | | Original | | 310690304-2 | |
| Star Trek VI: The Undiscovered Country (Disc 2) | CDI | | Original | | 310690304-2 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | CD-ICD-016-0 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Rerelease | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | | | CD-ICD-016-4 | |
| Star Trek: Armada II | PC | | Star Trek: Action Pack | | 31143.101.US | |
| Star Trek: D-A-C | PC | | Cosmi | | CDR164D1 | |
| Star Trek: Elite Force II (Disc 1) | MAC | | Original | | 10440-1CDA | |
| Star Trek: Elite Force II (Disc 2) | MAC | | Original | | 10440-2CDA | |
| Star Trek: Hidden Evil | PC | | Original | | 1000889.101.US | |
| Star Trek: Judgment Rites | PC | | Limited CD-ROM Collector's Edition | | | |
| Star Trek: Klingon Academy (Disc 1) | PC | | Original | | CD-C95-856-0 | |
| Star Trek: Klingon Academy (Disc 2) | PC | | Original | | CD-C95-856-1 | |
| Star Trek: Klingon Academy (Disc 3) | PC | | Original | | CD-C95-856-2 | |
| Star Trek: Klingon Academy (Disc 4) | PC | | Original | | CD-C95-856-3 | |
| Star Trek: Klingon Academy (Disc 5) | PC | | Original | | CD-C95-856-4 | |
| Star Trek: Klingon Academy (Disc 6) | PC | | Original | | CD-C95-856-5 | |
| Star Trek: New Worlds (Explore New Worlds) | PC | | Limited Edition | | CD-C95-1097-DS | |
| Star Trek: New Worlds | PC | | Demo | | CD-C95-1097-D | |
| Star Trek: Secret of Vulcan Fury (Non-Interactive Preview) | PC | | | | CD-C95-647-N1 | |
| Star Trek: Secret of Vulcan Fury (Non-Interactive Trailer) | PC | | | | CD-C95-647-N2 | |
| Star Trek: Shattered Universe | XBOX | | Original | | TM-016 | |
| Star Trek: Starfleet Academy: Chekov's Lost Missions | PC | | Original | | | |
| Star Trek: Starfleet Command (Bonus CD) | PC | | Original | | CD-C95-637-1 | |
| Star Trek: Starship Creator Deluxe | PC | | Original | | 0-671-31776-8 | |
| Star Trek: The Next Generation: Birth of the Federation | PC | | Original | | | |
| Star Trek: The Next Generation: Klingon Honor Guard (Game Disk) | MAC | | Original | | P/N 04-17512CD1 | |
| Star Trek: The Next Generation: Klingon Honor Guard (Install Disk) | MAC | | Original | | P/N 04-17512CD2 | |
| Star Trek: Voyager: Elite Force | MAC | | Original | | | |
| Star Warped | PC | | Original | | PAL-CD-10050A | |
| Star Wars Galaxies: 10-Day Trial | PC | | Original | | 8330530 | |
| Star Wars Galaxies: The Complete Online Adventures (Disc 1) | PC | | Original | | 8131830 | |
| Star Wars Trilogy CD-ROM: Limited Edition Entertainment Utility | PC | | Original | | | |
| Star Wars: Anakin's Speedway | PC | | Original | | #3518030 | |
| Star Wars: Attacktix: Battle Figure Game | PC | | Starter Set CD-ROM Series 2 | | | |
| Star Wars: Attacktix: Battle Figure Game | PC | | Starter Set CD-ROM | | | |
| Star Wars: Empire at War (Bonus Disc) | PC | | Original, Collector's Edition | | 8541832 | |
| Star Wars: Episode I: Cover Disk 4 | PC | | Press Kit | | | |
| Star Wars: Episode I: Disc #3: Covers | PC | | Press Kit | | | |
| Star Wars: Episode I: The Gungan Frontier | PC | | Demo | | #3519030 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 1) | PC | | Original | | 8531030 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 2) | PC | | Original | | 8531031 | |
| Star Wars: Jedi Knight Gold Pack | MAC | | Original | | 12280-1DDA | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Original | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Rerelease | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Rerelease | | 9521831 | |
| Star Wars: Jedi Starfighter | XBOX | | Original | | LA-005 | |
| Star Wars: Mac Pack | MAC | | Original | | 12300-1DDA | |
| Star Wars: Millennium Falcon CD-ROM Playset | PC | | Original | | | |
| Star Wars: Pit Droids | PC | | Scholastic | | P/N 9401321C | |
| Star Wars: Rebel Assault | MAC | | Demo | | CDRM1209730 | |
| Star Wars: Rebel Assault | MAC | | Original | | 634630, CDRM1208410 | |
| Star Wars: Rebel Assault | MCD | | Limited Run Games | | T-60075 | |
| Star Wars: Shadows of the Empire: Battle of Hoth | PC | | Bundle Version Diamond OEM | | 75000204-100 | |
| Star Wars: The Clone Wars | XBOX | | Original | | LA-004 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | MAC | | Original | | 12240-1DDA | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | MAC | | Original | | 12240-1DDA2 | |
| Star Wars: Yoda's Challenge | PC | | Original | | 3520030 | |
| Star Wars: Yoda's Challenge Activity Center | PC | | Demo | | #3529030 | |
| Starblade | MCD | | Original | | T-14025 | |
| Starbright Asthma CD-ROM Game: Quest for the Code | PC | | | | | |
| StarCraft II: Heart of the Swarm | PC | | Original | | | |
| Starfighter Assets CD | PC | | Press Kit | | | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67021 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67023 | |
| Starshine Legacy: Episode 2: Secret of Pine Hill Mansion | PC | | Original | | SLE2, US-61-0603 05 | |
| Starshine Legacy: Episode 4: The Riddle of the Dark Core | PC | | Original | | US: 61-0612 04 | |
| Starsky & Hutch | GC | | Original | | DL-DOL-GT5E-USA | |
| State of Emergency | XBOX | | Original | | TT-006 | |
| Steel Panthers III: Campaign Disk | PC | | Original | | 2220210-590001 | |
| Steel Panthers: Campaign Disk | PC | | Original | | 2209310-590001 | |
| Steel Soldiers | PC | | Original | | | |
| Stella Gets a New Brain! | PC | | Original | | AR-4601 | |
| Stellaluna | MAC | | Original | | 2069-1-01 | |
| Stellar 7 | PC | | Original | | | |
| Stellar 7 | PC | | | | | |
| Stellar 7 | PC | | 5 Ft 10 Pak In A Box Volume One | | | |
| A Steven Spielberg Film: Minority Report: Bonus CD-ROM! | PC | | Original | | | |
| Steven Spielberg's Director's Chair (Disc 1) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD100CD | |
| Steven Spielberg's Director's Chair (Disc 2) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD200CD | |
| Steven Spielberg's Director's Chair (Disc 3) Steven Spielberg's Director's Chair: Big Bucks. Big Stars. Big Problems. | PC | | | | ZZSDC10CD300CD | |
| Stickybear Family Fun | CDI | | Original | | 310690258-2 | |
| Stickybear Preschool | CDI | | Pre-Release Demonstration Disc | | 310-690-257-2 | |
| Still Life | XBOX | | Original | | MI-011 | |
| Stoked | XBOX360 | | Original | | DE-2003 | |
| Stoked: Big Air Edition | XBOX360 | | Original | | DE-2005 | |
| Stolen (Disc 1) (Game Disc) Stolen: Infiltrate · Steal · Vanish | PC | | Original | | | |
| Stolen (Disc 2) Stolen: Infiltrate · Steal · Vanish | PC | | Original | | | |
| Story Hour: Adventures | WII | | Original | | RVL-R3AE-USA | |
| Story Hour: Fairy Tales | WII | | Original | | RVL-R4FE-USA | |
| Story Lane Theater 1 | PSX | | Original | | LSP-990141 … | |
| Story Lane Theater 2 | PSX | | Original | | LSP-990142 … | |
| Story Lane Theater 3 | PSX | | Original | | LSP-990143 … | |
| Story Lane Theater 4 | PSX | | Original | | LSP-990144 … | |
| Story Lane Theater 5 | PSX | | Original | | LSP-990145 … | |
| Storybook Workshop | WII | | Original | | RVL-R4VE-USA-B0 | |
| Stowaway DK Multimedia: Stephen Biesty's Incredible Cross-Section: Stowaway | PC | | | | | |
| Strange Adventures in Infinite Space | PC | | Cheapass Games | | | |
| Stratosphere: Conquest of the Skies | PC | | Demo | | | |
| Strawberry Shortcake: Amazing Cookie Party | PC | | Scholastic | | P/N CDR9663741 | |
| Stray Souls: Dollhouse Story | PC | | Original | | | |
| Streak Hoverboard Racing | PSX | | Review | | SLUS-00629 | |
| Streak Hoverboard Racing | PSX | | Beta | | | |
| Street Fighter Alpha 2 | PC | | Original | | | |
| Street Fighter Alpha: Warriors' Dreams | PC | | Original | | | |
| Street Fighter Anniversary Collection | XBOX | | Original | | CC-015 | |
| Street Fighter II | PC | | Original | | 9108 | |
| Street Fighter IV: The Ties That Bind (Bonus Disc) | XBOX360 | | Xbox 360 Game Bundle | | CC-2033 | |
| Street Fighter Series | PC | | Original | | | |
| Street Fighter Series | PC | | Original | | | |
| Street Hoops | XBOX | | Original | | AV-003 | |
| Street Hoops | GC | | Original | | DL-DOL-GHPE-USA | |
| Street Legal | PC | | Original | | 30975.101.US | |
| Street Maps & Vacation Planner | PALM | | Cosmi | | PDA051501, PDA631D1 | |
| Street Sports: Jammit | PC | | Super 16 CD Pak Volume 2 | | MQ 13-004-166 | |
| Streets of SimCity | PC | | Ultimate Sim Series | | 10402 | |
| Strike Commander | PC | | CD-ROM Classics | | | |
| Strike Commander | PC | | EA Gold CD-ROM Classics | | | |
| Strike Force Bowling | XBOX | | Original | | CV-008 | |
| Strike Force Bowling | GC | | Original | | DL-DOL-G5BE-USA | |
| Stronghold (Bonus Castle: The Tower of London) | PC | | Pre-Order Bonus | | | |
| Stronghold 3 | PC | | Original | | 50070-LBL | |
| Stronghold 3 Gold Stronghold 3: Gold | PC | | Original | | 50080-LBL | |
| The Stronghold Collection | PC | | Original | | 31684-1 | |
| Stronghold Crusader | PC | | Interactive Demo | | | |
| Stuart Little 2 | PSX | | Beta | | SCUS-94669 | |
| Stuart Little 2 | PC | | Rerelease | | Part # 23532CD | |
| Su-27 Flanker Mission Disk | PC | | Original | | 2212510-590001 | |
| Sub Command (Disc 1) Sub Command: Akula Seawolf 688(I) | PC | | Naval Combat Pack | | 903366CD3 | |
| Sub Command (Disc 2) Sub Command: Akula Seawolf 688(I) | PC | | Naval Combat Pack | | 903366CD4 | |
| Sub Culture | PC | | Original | | | |
| Sudoku | GAMEWAVE | | Original | | G230 | |
| The Sudoku Challenge! Collection | PC | | Original | | | |
| Sudoku Crunch for Kids! | PC | | Original | | P/N 61081-CD | |
| Sudoku Master | PC | | Rerelease | | 03659 | |
| Sudoku Master | PALM | | Original | | 3340R-2006-03-CDA-US | |
| The Suffering | XBOX | | Original | | MW-021 | |
| The Suffering: Ties That Bind (Disc 1) | PC | | Original | | | |
| The Suffering: Ties That Bind (Disc 2) | PC | | Original | | | |
| The Suffering: Ties That Bind (Disc 3) | PC | | Original | | | |
| The Sum of All Fears | GC | | Original | | DL-DOL-G3ME-USA | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Summer Athletics: The Ultimate Challenge | XBOX360 | | Original | | CV-2004 | |
| Summer Refresh 2011: 3.65 IDU FW Update | PS3 | | Kiosk Demo | | | |
| Summer Sports 2: Island Sports Party | WII | | Original | | RVL-RI6E-USA-B0 | |
| Summer Sports: Paradise Island | WII | | Original | | RVL-RSUE-USA | |
| Summer Stars 2012 | WII | | Original | | RVL-SSJE-USA-B0 | |
| Suncom Technologies Presents: 10 Hit Games by Apogee | PC | | Original | | 63-0647 | |
| Sundance Channel: Sept. 2000 | PHOTO-CD | | | | | |
| Super 3D Noah's Ark | PC | | Original | | | |
| Super Air Zonk: Rockabilly-Paradise | PCE | | Original | | TGXCD1042 | |
| Super Bean | PC | | SelectSoft (CD-R) | | MPSI 44459 | |
| Super Breakout | PC | | Pocketware | | P/N: LTATPSUBRP | |
| Super Bubble Pop | XBOX | | Original | | JA-004 | |
| Super Bubble Pop | GC | | Original | | DL-DOL-GBYE-USA | |
| Super Collapse! 3 | PC | | Original | | | |
| Super Fruit Fall | WII | | Original | | RVL-RF4E-USA | |
| Super Game Pak | PALM | | Ultimate Game Collection, Cosmi | | PDA102501, PDA634D1 | |
| Super GameHouse Solitaire Collection | PC | | Original | | | |
| Super Huey III | PC | | Cosmi | | CDR 707 D1, SJ 111000 | |
| Super Huey III: Combat & Rescue / Spy Hunter/Sub Attack | PC | | Original | | CDRS409CD1 | |
| Super Meat Boy (Installation Disc) | PC | | IndieBox | | | |
| Super Meat Boy: Ultra Edition | PC | | Original | | | |
| Super Monkey Ball Deluxe | XBOX | | Original | | SE-056 | |
| Super Munchers | PC | | SoftKey | | PSM944BE-CD | |
| Super PickUps | WII | | Original | | RVL-RQUE-USA-B0 | |
| Super Puzzle Fighter II Turbo | PC | | Original | | | |
| Super Scattergories | PC | | Scholastic | | | |
| Super Shot Soccer | PSX | | Original | | SLUS-01464 | |
| Super Solvers Reading Ages 9-12 | PC | | Original | | SMR744AE-CD | |
| Super Stories: Mom is Going to Stop It | CDI | | | | | |
| Super Stories: My Favorite Things | CDI | | | | | |
| Super Street Fighter II Turbo HD Remix (Asset Disc) | PC | | Super Turbo Hyper Champion Special Edition Pack | | | |
| Super Strike Trilogy | MCD | | Unlicensed | | | |
| Super Swing Golf | WII | | Original | | RVL-RPYE-USA | |
| Super Swing Golf Season 2 | WII | | Original | | RVL-R2PE-USA | |
| Super Why! The Power to Read | PC | | Original | | 23899-00 | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | CD-ROM Classics | | 1215007 | |
| Superbike 2001 | PC | | Original | | 1421707 | |
| SuperCharged Xpansion Pack SuperCharged Xpansion Pack for Doom, Doom II & Hexen | PC | | Rerelease | | | |
| Supercow | PC | | Original | | P/N 61261-CD | |
| Superdead | PC | | Original | | | |
| Superman | PSX | | Prototype | | | |
| Superman Returns | XBOX | | Original | | EA-160 | |
| Superman Returns | XBOX360 | | Original | | EA-2029 | |
| Superman: The Man of Steel | XBOX | | Original | | IG-022 | |
| Supreme Commander | XBOX360 | | Original | | AY-2001 | |
| Supreme Commander | PC | | Original | | P/N: 120904-B | |
| Supreme Commander (Bonus Disc) | PC | | Original | | | |
| Supreme Warrior (Disc 1) (Fire & Earth) | MCD | | Original | | T162045 | |
| Supreme Warrior (Disc 1) (Fire & Earth) | MCD | | Original | | T162045 | |
| Surf's Up | XBOX360 | | Original | | US-2041 | |
| Surf's Up | WII | | Original | | RVL-RXUE-USA | |
| Surf's Up | GC | | Original | | DL-DOL-GXUE-USA | |
| Surface: Mystery of Another World | PC | | Collector's Edition | | 33418010US | |
| Surgical Strike | MCD | | Original | | 4435 | |
| A Survey of Western Art: The Electronic Library of Art | VIS | | Original | | 25-6153 | |
| Survivor | WII | | Original | | RVL-RLNE-USA-B0 | |
| SWAT 4 | PC | | Demo | | | |
| SWAT: Career Pack (Disc 4) (Police Quest: SWAT) | PC | | Original | | | |
| SWAT: Global Strike Team | XBOX | | Original | | VV-037 | |
| Swift Classics Card Games for Windows | PC | | Cosmi | | CDR 720 OD1, SJ 041001 G | |
| SwiftWare | PALM | | Cosmi | | PDA060501, PDAMC1 | |
| Swingerz Golf | GC | | Original | | DL-DOL-GWGE-USA | |
| Switchball | PC | | Original | | S7275110 | |
| Swords | WII | | Original | | RVL-SSZE-USA-B0 | |
| SX Superstar | GC | | Original | | DL-DOL-GS3E-USA | |
| SX Superstar | XBOX | | Original | | AC-016 | |
| SydMead's TerraForming | PCE | | Original | | TGXCD1040 | |
| Symbiocom | PC | | Original | | | |
| Symbol Set 1: Fantasy Overland | PC | | Original | | | |
| Symbol Set 2: Fantasy Floorplans | PC | | Original | | | |
| Syndicate | MAC | | Original | | 7558 | |
| Syndicate Plus | PC | | CD-ROM Classics: Gold Edition | | 5737 | |
| Syndicate Plus | PC | | Bundle Version OEM | | | |
| Syndicate Wars | PC | | | | EA 768207 | |
| Syphon Filter 2 (Disc 2) | PSX | | Preview Version | | PSRM-01710 … | |
| System Shock | MAC | | Original | | EA 568407 | |
| Systemax Ultimate Software Collection (Disc 01) (Daria's Inferno / Who Wants to Beat Up a Millionaire) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 02) (I See Sue... the T. Rex / Amazons & Aliens / Cheerios: Playtime) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 03) (How Many Bugs in a Box? / More Bugs in Boxes / Jim Henson's Muppet Babies: Toyland Train / Miss Spider's Tea Party) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 04) (Forbes: Corporate Warrior / Starwebs: Web Shop / Writing Tutor / Complete Idiots Guide: Marketing Materials Maker) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 05) (S&S Encyclopedia / Typing Tutor 12) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 06) (Women's Fitness / Christina Aguilera: Follow Your Dreams) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 08) (Garfield: Mad About Cats / Money Town) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 09) (Darkened Skye: Disc 1 / Zoboomafoo with the Kratt Brothers Animal Kids) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 10) (Deer Avenger / Ski-Doo X-Team Racing) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 11) (Pearl Harbor: Zero Hour / Real War) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 12) (S&S Encyclopedia of Science / Curious George: Reads, Writes and Spells) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 13) (Multimedia Billiards / Astrology Starscopes / Music Match Juke Box Deluxe 6.1 / Extreme Chess / Typing Tutor Jr. / Bumper Wars) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 14) (Darkened Skye: Disc 2) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 18) (M&M's: The Lost Formulas) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 21) (Mob Rule) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 26) (Sabrina, the Teenage Witch: Brat Attack) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 27) (Star Trek: Deep Space Nine - The Fallen) | PC | | Original | | | |
| Secret Agent Clank | PSP | .01 | Beta | | UCUS-98697 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| Slingo Quest | PC | 0.0.0.104 | Original | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Sunny Garcia Surfing | PS2 | 0.01 | Original | | SLUS-20208 | |
| Superbike World Championship | PC | 0.1.0.24 | Ultimate Motorcycle Series | | 799607 | |
| Syphon Filter: Logan's Shadow | PSP | 0.10 | Test Sample | | UCUS-98606 | |
| Super Mario's Wacky Worlds | CDI | 0.11 | Prototype | | | |
| Star Trek: Voyager: Elite Force | PC | 0.28 | Bundle Version Linksys OEM | | 1000912.101.US | |
| Starship Troopers | PC | 0.3.2.69 | Original | | P/N 21121-5 | |
| Sonic Mega Collection Plus | PS2 | 0.80 | Beta | | | |
| Schizm: Mysterious Journey | PC | 0.99 | Playable Demo | | | |
| Sleeping Dogs | PS3 | 00.00 | Preview | | | |
| Self Selling Disc | CDI | 01 | Original | | | |
| Saints Row: The Third: The Full Package | PS3 | 01.00 | Original | | BLUS-31062 | |
| The Sims 3: Pets | PS3 | 01.00 | Original | | BLUS-30803 | |
| Skylanders: Imaginators | PS3 | 01.00 | Portal Owners Pack | | BLUS-31600 | |
| Skylanders: SuperChargers | PS3 | 01.00 | Starter Pack | | BLUS-31545 | |
| Sniper Elite III: Ultimate Edition | PS3 | 01.00 | Original | | BLUS-31532 | |
| Sniper Elite V2: Silver Star Edition | PS3 | 01.00 | Original | | BLUS-41022 | |
| Spider-Man 3 | PS3 | 01.00 | Original | | BLUS-30031 | |
| Spider-Man 3 | PS3 | 01.00 | Collector's Edition | | BLUS-30030 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition | PS3 | 01.00 | Original | | BLUS-30445 | |
| Surf's Up | PS3 | 01.00 | Original | | BLUS 30046 | |
| Shaun White Snowboarding | PS3 | 01.01 | Target Limited Edition | | BLUS-30233 | |
| Silent Hill: Downpour | PS3 | 01.01 | Review | | | |
| Skylanders: Trap Team | PS3 | 01.01 | Starter Pack | | BLUS-31442 | |
| Steins;Gate | PS3 | 01.01 | Original | | BLUS-31538 | |
| Strike Fighters: Project 1 | PC | 01.16.03 | Rerelease | | 10318 | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD950001D | |
| Sabre Ace: Conflict over Korea | PC | 1.0 | Original | | D83115 | |
| Sacred Gold (Disc 2) | PC | 1.0 | Original | | 10130-CD2 | |
| Sacred Gold (Disc 3) | PC | 1.0 | Original | | 10130-CD3 | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.0 | Original | | PCO519CD | |
| Sammy's Science House | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| SAS: Secure Tomorrow | PC | 1.0 | Original | | | |
| Savage Warriors | PC | 1.0 | Original | | 2205110-S90001/1055SA | |
| Savage Warriors | PC | 1.0 | Original | | | |
| Savage: The Battle for Newerth | PC | 1.0 | Original | | | |
| Savage: The Ultimate Quest for Survival | PC | 1.0 | | | | |
| Save Planet Polluto | PC | 1.0 | Original | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Schoolhouse Rock! Grammar Rock | PC | 1.0 | Scholastic | | P/N CDR9835984 | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sesame Street: My Baby & Me (Disc 1) (Baby & Me) | PC | 1.0 | Original | | SSY744AE-CD1 | |
| Sesame Street: My Baby & Me (Disc 2) (Sesame Street Greatest Hits Sampler) | PC | 1.0 | Original | | SSY744AE-CD2 | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shannara | PC | 1.0 | Rerelease | | 7-81055-33802-6 | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| ShellShock 2: Blood Trails | PC | 1.0 | Original | | 5000026211 | |
| Shivers Two: Harvest of Souls | PC | 1.0 | Demo | | | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| ShowMaster | CDI | 1.0 | Demo | | | |
| Shrek 2: Team Action | PC | 1.0 | Original | | 32789.101.US | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sierra Pro Pilot (Disc 1) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot (Disc 2) | PC | 1.0 | Original | | | |
| Silent Hunter | PC | 1.0 | Rerelease | | WWD144AE-CD | |
| Silkolene Honda Motocross GP | PC | 1.0 | Original | | 13030 | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity 4 (Disc 1) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 (Disc 2) | MAC | 1.0 | Original | | 10350-1CDA | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4: Rush Hour | PC | 1.0 | Original | | 1472207 | |
| SimCity Enhanced CD-ROM | PC | 1.0 | Rerelease | | CD-ICD-508-0 | |
| SimGolf | PC | 1.0 | Original | | 0093-000-0601-A | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| The Sims 2 (Disc 4) | PC | 1.0 | Original | | 1472637 | |
| The Sims Castaway Stories | PC | 1.0 | Original | | 1575007 | |
| The Sims Online (Disc 1) | PC | 1.0 | Charter Edition | | 1461517 | |
| The Sims Online (Disc 2) | PC | 1.0 | Charter Edition | | 1461527 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | 1457637 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Scholastic | | 1459517 | |