| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Search for the Sea | VIS | | Original |  | 25-6143 |  |
 | SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| Secret Weapons over Normandy | PS2 | 1.00 | Review Build | | SLUS-20762 | |
| The Secrets of Alamût (Disc 1)
The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2)
The Secrets of Alamût: The Legend 2 | PC | | | | | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
 | Section 8: Prejudice | PS3 | 01.00 | Beta | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Sega CD Demo | MCD | | Prototype | | | |
| Sega Classics Arcade Collection | MCD | 1.00 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega E3 Press Kit 2005
2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Flash Vol. 1 | SS | 1.001 | Bundled with Sega Saturn | | MK610-6288A | |
 | Sega Flash Vol. 2 | SS | 1.000 | Bundled with Magazine, Bundled with Audio CD | | 610-6288B | |
| Sega Flash Vol. 3 | SS | 1.001 | Bundled with Magazine | | 610-6288C | |
| Sega Flash Vol. 3 | SS | 1.004 | Bundled with Magazine | | 610-6288C | |
| Sega Flash Vol. 4 | SS | 1.003 | Bundled with Magazine | | 610-6288D | |
| Sega Flash Vol. 5 | SS | 1.002 | Bundled with Magazine, Bundled with Sega Saturn | | 610-6288E | |
| Sega Flash Vol. 6 | SS | 1.000 | Bundled with Magazine | | 610-6288F | |
| Sega Flash Vol. 7 | SS | 1.000 | Bundled with Magazine | | MK610-6288G | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
 | Sega Rally 2 (Install Disc)
Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Play Disc)
Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
 | Sega Rally Championship
세가 랠리 | SS | 1.000 | Original | | GS-9506J, MK-81207-08 | |
| Sega Rally Championship
Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
 | Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship PC
セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC
セガラリー・チャンピオンシップ | PC | | Mihon-hin | | 670-10314 | |
| Sega Rally Revo | PSP | 1.00 | Original | | ULUS-10311 | |
| Sega Saturn Bootleg II: On the Road
Sega Screams Volume 1 | SS | 1.002 | Not for Resale | | 81068, 81075 | |
| Sega Saturn Choice Cuts | SS | 1.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Saturn Choice Cuts | SS | 2.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Screams Volume 2 | SS | 2.000 | Not for Resale | | 81077 | |
| Sega Screenshots 2000
Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Selector Demo 04
PlayStation 2 Official Demo Disc Retail Edition 4 | PS2 | 1.00 | | | SCED-51269 | |
 | Senha N. 1 | PC | | | | | |
| Sentient | PC | | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00I | Original | | | |
 | Septerra Core: Legacy of the Creator | PC | 1.00I | Covermount | | | |
 | Septerra Core: Legacy of the Creator | PC | 1.00I | Covermount | | | |
| Serious Sam: Next Encounter | GC | Rev 1 | Original | | DL-DOL-G3BE-USA | |
| Serious Sam: The First Encounter | PC | | | | | |
 | Serious Sam: The First Encounter
英雄萨姆 | PC | 1.00 | Original, Zhima Kai Men | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the Fun of It! | | EOA844AE-CD, KES005 | |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Sesame Street Toddler | PC | | Adventure Workshop Tots | | 32180-CD1 v1.0 | |
| Sesame Street Toddler (Disc 2) (Elmo's Art Workshop) | PC | 3.0 | Rerelease | | STL744AE-CD2 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Computer Phone | PC | 1.00 | Bundled with Toy Phone | | | |
| Sesame Street: Elmo's Deep Sea Adventure | PC | 1.0 | Sesame Street: Amazing Adventures Deluxe Collection | | 19800-CD1 v1.0 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Preschool (Disc 1) (Elmo's Preschool) | PC | 3.1 | Original | | P/N 379663-CD1 | |
| Sesame Street: Elmo's Preschool (Disc 2) (Search & Learn Adventures) | PC | 3.1 | Original | | P/N 379663-CD2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: Ernie's Adventures in Space | PC | 1.0 | Sesame Street: Amazing Adventures Deluxe Collection | | 19800-CD2 v1.0 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: Let's Make a Word! | PC | | Software for the Fun of It! | | KES006 | |
| Sesame Street: Let's Make a Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Let's Make a Word! | PC | | Original | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Music Maker | PC | | Original | | | |
| Sesame Street: My Baby & Me (Disc 1) (Baby & Me) | PC | 1.0 | Original | | SSY744AE-CD1 | |
| Sesame Street: My Baby & Me (Disc 2) (Sesame Street Greatest Hits Sampler) | PC | 1.0 | Original | | SSY744AE-CD2 | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Sesame Street: The Adventures of Elmo in Grouchland | PC | | Original | | 24138-0919 | |
| Sesame Street: The Adventures of Elmo in Grouchland | PC | 1.0 | Sesame Street: Amazing Adventures Deluxe Collection | | 19800-CD3 v1.0 | |
