Region | Title | System | Version | Edition | Languages | Serial | Status |
| Los Sims: Superstar (Disc 1) | PC | 1.80 | EA Classics | | MXS08004759D1 | |
| Los Sims: Superstar (Disc 2) | PC | 1.80 | EA Classics | | MXS08004759D2 | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Sid Meier's SimGolf | PC | 1.01 | EA Classics | | CD 796 | |
| Super City Create City | PC | 1.0 | Original, Covermount | | | |
| Super League Pro Rugby Super League Rugby | PC | | Serie Plus | | | |
| Super Trailer City Trailer Park Tycoon | PC | 1.0.0.1 | Covermount | | | |
| Superbike Challenge | PC | | Covermount | | | |
| SuperBikes Racing SuperMoto Racing | PC | | Original, Covermount | | | |
| Street Fighter IV | PC | 1.0.0.1 | Original | | SYX26084GM | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Split/Second Split/Second: Velocity | PC | | Original | | 8004905, SYX26187GM | |
| Shogun: Total War: Gold Edition | PC | 1.00 | Total War: Eras | | SYX26218GM1 | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| Sub Culture | PC | | Covermount | | 981009 | |
| Sabre Ace | PC | 1.0 | Covermount | | | |
| Sacred: La Leyenda del Arma Sagrada | PC | 1.8.80 | DVD-ROM | | ES v.1.8 DVD | |
| Sócrates en la Casa del Terror Sócrates en la Casa Embrujada | PC | | Covermount | | | |
| Soulbringer (Disc 1) | PC | 1.0.0.1 | Original | | | |
| Soulbringer (Disc 2) | PC | 1.0.0.1 | Original | | | |
| Space Invaders | PC | | Covermount | | | |
| Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |