| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Zipi y Zape: La casa del terror | PC | | Original |  | |  |
| Zipi y Zape: La vuelta al mundo | PC | 1.0 | Original | | | |
 | Zeneca Pharmaceuticals Group: Experts in Anti-Infectives: Pathogen Pursuit: An Interactive Medical Program | CDI | | Original |  | | |
| Zero Critical | PC | | Original | | | |
 | Zavoevanie Ameriki
Завоевание Америки | PC | | Original | | RUSSOBIT-M 2003/327 | |
| Zeppelin!
Zeppelin: Giants of the Sky | PC | | Original | | 042840101 | |
 | Zoom: Paparazzi in Action | PC | | Original | | 3760137141898 | |
 | Zeus: Pan Olimpu: Złota Edycja | PC | 2.0 | eXtra Klasyka Next |  | S1003877 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Zoo Tycoon | PC | 10.10.00.0009 | Zoo Tycoon: Complete Collection | | 0603 Part No. X09-79593, 0803 Part No. X10-10290 | |
| Zork Nemesis: The Forbidden Lands (Disc 3) | PC | 1.0 | Original, Zork Legacy Collection | | 1000028-103-US, 1000168.103.US, CDD-3112-103-U3 | |
| Zodiac Ultimate Game Pack | PC | | Original | | | |
| Zoombinis: Mountain Rescue | PC | | Adventure Workshop: 4th-6th Grade | | 382199-CD1 | |
 | Zombie Revenge
ゾンビ リベンジ | DC | 1.006 | Original |  | HDR-0026 | |
 | ZooG Genius: Language Arts, History & Geography | PC | | Original | | G2240 | |
| Zoku Gekka Bijin: Ouka no Koro
続月花美人 ～桜花の頃～ | PC | | Original | | JSP-008 | |
| Zhadnost: The People's Party | 3DO | 6/11/95 | Beta (CD-R) | | | |
| Zero4 Champ DooZy-J Type-R
ゼロヨンチャンプ ドゥーヅィージェイ タイプ−アール | SS | 1.003 | Original | | T-21401G | |
 | Zuma Deluxe | PC | | Original | | SKU-E105894 | |
| Zoboomafoo: Animal Kids | PC | 1.0 | Original | | 14000-CD1 | |
| Zoboomafoo: Animal Alphabet | PC | | Cosmi | | CDRZ965D1, SJ100505 | |
| Zoboomafoo: Animal Alphabet | PC | 1.1 | | | 381344A-CD | |
| Zuma Deluxe | PC | 1.0 | PopCap's Greatest Hits, PopCap 5 Star Favorites | | | |
| Zettai Zetsumei Toshi 2: Itetsuita Kioku-tachi
絶体絶命都市２ ー凍てついた記憶たちー | PS2 | 1.02 | Taikenban Type-A | | SLPM 60254 | |
| Zettai Zetsumei Toshi 2: Itetsuita Kioku-tachi
絶体絶命都市２ ー凍てついた記憶たちー | PS2 | 1.01 | Taikenban Type-B | | SLPM 60273 | |
 | Zoologic
Beestenboel Zoölogic | PC | 1.0 | PC CD-ROM Top |  | MMICDR 5001 | |
 | Zhuangjia Jingying: Tanke Jujishou (Ziliaopan)
装甲精英：坦克狙击手 | PC | | Original |   | | |
| Zhuangjia Jingying: Tanke Jujishou
装甲精英：坦克狙击手 | PC | 1.1 SE | Original, Rerelease | | | |
| Zhanzheng Qishilu
战争启示录 | PC | 1.0 | Original, Youxi Zhizhu (Zeng: Zhanzheng Qishilu) | | | |
 | Zaphie 2
제피 2 | PC | | Original |  | | |
| Zoo Tycoon 2 | PC | 20.11.00.0007 | Rerelease | | 0804 Part No. X10-74059 | |
| Zeddas: Servant of Sheol | PC | | Original | | | |
| Zoo Tycoon 2: Extinct Animals | PC | 32.10.0.9 | Original, Zookeeper Collection | | 0707 Part No. X13-85741-01, X13-85741-01 | |
| Zoo Tycoon 2: Marine Mania | PC | | Original, Zookeeper Collection | | 0706 Part No. X12-79927-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 1) | PC | 30.08.00.0009 | Original | | 0806 Part No. X12-80044-01 | |
| Zoo Tycoon 2: Zookeeper Collection (Disc 2) | PC | 30.08.00.0009 | Original | | 0806 Part No. X12-80045-01 | |
