Region | Title | System | Version | Edition | Languages | Serial | Status |
| Earth: A Multimedia Guide to Changing Environment | CDI | | Original | | 779461000224 | |
| EA Sports Active 2: Personal Trainer | XBOX360 | | Bundled with Heart Rate Monitor | | EA-2321 | |
| The Emperor's New Clothes | CDI | | Original | | 310690042-2, 699 042-2 | |
| eScape | CDI | | Original, Head Crash: Limited Edition Triple Pack | | 810 0117 | |
| EyePet & Friends | PS3 | 01.00 | Original, Promo (PlayStation Move Press Kit) | | BCES-00865 … | |
| EyeToy Play: Astro Zoo | PS2 | 1.00 | Promo, Bundled with EyeToy | | SCES-54538 … | |
| Earth Command | CDI | 1.07 | Original | | 812 0072 | |
| The Elder Scrolls IV: Oblivion: Edition Jeu de L'Année (Disc 1) | XBOX360 | | Original | | BS-2001 | |
| The Elder Scrolls IV: Oblivion: Edition Jeu de L'Année (Disc 2) | XBOX360 | | Original | | BS-2001 | |
| Etoiles et Galaxies: Astronomie Flammarion | CDI | 2.01 | Original | | 812 0091 | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 1994 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 1996 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 1997 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 1998 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 1999 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 2000 | CDI | | Original | | | |
| Enciclopedia Elettronica Multimediale Grolier: Edizione 2001 | CDI | | Original | | | |
| Enkhuizer Almanak 1997 | CDI | | Original | | 90 5094 001 | |
| Europa Universalis II | PC | | Original | | | |
| Evil Islands: Curse of the Lost Soul BGamer 055 (Disc 1) | PC | 1.05 | Covermount | | | |
| Extreme Assault BGamer 060 (Disc 1) | PC | | Covermount | | | |
| Extreme Sports Pepsi Max Extreme Sports | PC | | Covermount | | MFCD02601 | |
| Engineering 5.0 | CDI | | Demo | | | |
| The Elder Scrolls IV: Oblivion: Game of the Year Edition (Disc 2) | XBOX360 | | Original, The Elder Scrolls IV: Shivering Isles | | BS-2001 | |
| Escape from CyberCity | CDI | | Original, Demonstration Disc, Nur für Demonstrationszwecke | | 310-690-071-2, 310690071-2, 690 071-2, 690 0712, 810 0005, 812 0043, 813 0041, 815 0029 | |
| Escape from Monkey Island (Disc 1) | MAC | | OEM Bundle | | 1101830 / CD-MCR1997-HSE1 | |
| Escape from Monkey Island (Disc 2) | MAC | | OEM Bundle | | 1101831 / CD-MCR1997-HSE2 | |
| The Evil Within | XBOX360 | | Original | | BS-2036 | |