Region | Title | System | Version | Edition | Languages | Serial | Status |
| I Have No Mouth, and I Must Scream | PC | | Original | | | |
| Ian Livingstone's Deathtrap Dungeon | PC | 1.0 | Original | | | |
| In Cold Blood (Disc 1) | PC | 1.0 | Original | | | |
| In Cold Blood (Disc 2) | PC | 1.0 | Original | | | |
| In Cold Blood (Disc 3) | PC | 1.0 | Original | | | |
| The Island of Dr. Brain | PC | 1.0 | SierraOriginals | | | |
| Indiana Jones and the Infernal Machine (Disc 1) | PC | 1.0 | Original | | 3000020.101.UK, 6511830 | |
| Indiana Jones and the Infernal Machine (Disc 2) | PC | 1.0 | Original | | 3000020.102.UK, 6511831 | |
| Intellivision Greatest Hits: 20th Anniversary Edition | PC | 1.0 | Original | | 382040-CD | |
| Indiana Jones and the Fate of Atlantis | PC | | Original | | 632331, CDRM1111250, CDRS1111250 | |
| Indiana Jones and the Emperor's Tomb (Disc 1) | PC | 1.00 | Original | | 6601830 | |
| Indiana Jones and the Emperor's Tomb (Disc 2) | PC | 1.00 | Original | | 6601831 | |
| Icewind Dale (Disc 1) | PC | 1.00 | Original | | CD-C95-1156-0 | |
| Icewind Dale (Disc 2) | PC | 1.00 | Original | | CD-C95-1156-1 | |
| Icewind Dale: Heart of Winter | PC | 1.40 | Original | | CD-C95-1253-0 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 1) Cyberia / SimCity Enhanced CD-ROM / Bonus Sampler | PC | | Original | | CD-ICD-355-1 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 2) Frankenstein: Through the Eyes of the Monster / Blackthorne / Bonus Sampler | PC | | Original | | CD-ICD-355-2 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 3) Castles II: Siege & Conquest | PC | | Original | | CD-ICD-355-3 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 4) Battle Chess Collection | PC | | Original | | CD-ICD-355-4 | |
| Iron Helix | PC | 1.25E | Original | | HLXCD140 1-126-40-101 | |
| Inca | PC | 1.001 | Original, SoftKey | | INA344AE-CD | |
| Inca II: Wiracocha | PC | 1.07 | Original | | S536430 | |
| Icewind Dale II (Disc 1) | PC | 2.00 (072215) | Original, Icewind Dale: The Ultimate Collection | | S7162710 | |
| Icewind Dale II (Disc 2) | PC | 2.00 (072215) | Original, Icewind Dale: The Ultimate Collection | | S7162720 | |
| Icewind Dale II: Adventure Pack (Bonus Disc) | PC | | Pre-Order, Icewind Dale: Complete Collection, Icewind Dale: The Ultimate Collection | | W8523810 | |