Region | Title | System | Version | Edition | Languages | Serial | Status |
| S.C.A.R.S. | PC | 1.0 | | | | |
| S.S.D.S.: Setsuna no Akogare S.S.D.S. ー刹那の英雄- | PC | | Original | | | |
| S.T.A.L.K.E.R.: Call of Pripyat (Soundtrack CD) | PC | | Special Edition | | | |
| S.T.A.L.K.E.R.: Chistoe Nebo S.T.A.L.K.E.R.: Чистое Небо | PC | 1.5.00 | Original | | | |
| S.T.A.L.K.E.R.: Chistoe Nebo S.T.A.L.K.E.R.: Чистое Небо | PC | 1.5.00 | Original | | | |
| S.T.A.L.K.E.R.: Clear Sky (Assets) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Clear Sky BGamer 168 | PC | 1.5.10 | Covermount | | | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.5.04 | Legjobb Választás | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | | Original, Radiation Edition | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0000 | Original | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0001 | Original | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0006 | Original | | | |
| S.T.A.L.K.E.R.: Zov Pripyati S.T.A.L.K.E.R.: Зов Припяти | PC | | Original | | | |
| S.T.A.L.K.E.R.: Zov Pripyati S.T.A.L.K.E.R.: Зов Припяти | PC | 1.6.00 | Original | | | |
| S.T.A.L.K.E.R.: Zov Pripyati S.T.A.L.K.E.R.: Зов Припяти | PC | 1.6.00 | Original | | | |
| S.T.A.L.K.E.R.: Zov Pripyati S.T.A.L.K.E.R.: Зов Припяти | PC | 1.6.00 | Original | | | |
| S.W.I.N.E. (PlayDisk) 猪兔大战 | PC | 1.2 | Original | | | |
| S.W.I.N.E. (Disc 1) 猪兔大战 | PC | 1.2 | Original | | | |
| S³: Silent Storm: Sentinels | PC | 1.1 | Gold Edition | | | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| Sabotage: Break the Rules (Disc 1) Саботаж: Кулак Империи | PC | 1.0 | Original | | | |
| Sabotage: Break the Rules (Disc 2) Саботаж: Кулак Империи | PC | 1.0 | Original | | | |
| The Saboteur | PC | 1.0 | Original | | | |
| Sabre Ace | PC | 1.0 | Covermount | | | |
| Sacred (Disc 1) | PC | | | | | |
| Sacred (Disc 2) | PC | | | | | |
| Sacred | PC | 1.8.28 | Software Pyramide | | | |
| Sacred 2: Fallen Angel (Digital Press-Kit: Games Convention 2008) | PC | | Press Kit | | | |
| Sacred 2: Fallen Angel (Disc 1) Sacred 2: Падший ангел | PC | 2.0.2 build 1371 | Original | | | |
| Sacred 2: Fallen Angel (Disc 1) Sacred 2: Падший ангел | PC | 2.0.2 build 1371 | Original | | | |
| Sacred 2: Fallen Angel (Disc 2) Sacred 2: Падший ангел | PC | | Original | | | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| The Sacred Amulet | PC | | Original | | | |
| Sacred Gold | PC | | Linux (LGP) | | | |
| Sacrifice (Disc 1) | PC | 0521.12.14 | Original | | | |
| Sacrifice (Disc 2) | PC | 0521.12.14 | Original | | | |
| Sacrifice (Disc 3) (Poradnik do Edytora Scapex) | PC | | Original | | | |
| Sacrifice (Editors Press Kit) | PC | | Press Kit | | | |
| Sacrifice (Scapex Tutorial Video) | PC | | Preproduction | | | |
| Sacrifice: Kamigami no Houkou サクリファイス ~神々の咆哮~ | PC | 0533.01.12 | Original | | | |
| Safari Kongo | PC | 1.2 | Original | | | |
| Safecracker | MAC | | Original | | | |
| Safecracker | PC | | Rerelease | | | |
| Safecracker | PC | | Original, Gamez Classic / PC Zone Benelux Klassieker | | | |
| Saga Baldur's Gate | PC | | eXtra Klasyka GOLD | | | |
| Saga Fallout | PC | | eXtra Klasyka neXt | | | |
| Saga Heroes of Might and Magic I-III (Heroes of Might and Magic) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Heroes of Might and Magic II) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Disc 1) (Heroes of Might and Magic III) | PC | | eXtra Klasyka Next | | | |
| Saga Heroes of Might and Magic I-III (Disc 2) (Heroes of Might and Magic III) | PC | | eXtra Klasyka Next | | | |
| Saga The Settlers I-IV (The Settlers I + II) | PC | | eXtra Klasyka XK Gold | | | |
| Saga The Settlers I-IV (The Settlers III: Złota Edycja - Disc 1) | PC | 1.60 | eXtra Klasyka XK Gold | | | |
| Saga The Settlers I-IV (The Settlers III: Złota Edycja - Disc 2) | PC | 1.60 | eXtra Klasyka XK Gold | | | |
| Saga The Settlers I-IV (The Settlers IV: Złota Edycja) | PC | 2.50.1516 | eXtra Klasyka XK Gold | | | |
| Sage: Rage of Kings | PC | | Covermount | | | |
| Saikyou Kareshi: Dynamic Darling 最強彼氏 | MAC | | Original | | | |
| Sailing: Baltic Sea Под Парусом: Балтика и Северное море | PC | | Original | | | |
| Saint Eyes セイントアイズ | PC | | Shokai Genteiban | | | |
| Saint Seiya: Sanctuary Battle | PS3 | 01.00 | Beta | | | |
| Saint Seiya: Typing Ryuuseiken 聖闘士星矢 タイピング流星拳 | PC | | Original | | | |
| Saints Row (Assets Disk) | PC | | Press Kit | | | |
| Saints Row 2 | PC | | Covermount | | | |
| Saints Row 2 | PC | | Original | | | |
| Saints Row 2 黑街聖徒2 | PC | | Original | | | |
| Sakura no Mori 櫻の杜 | FMT | | PC-9821 Release | | | |
| Sakura Taisen Monogatari: Mysterious Paris: Special Disc サクラ大戦物語 ~ミステリアス巴里~ Special Disc | PC | | Promo | | | |
| Sakura Wars Войны Сакуры | PC | | Original | | | |
| Sakura Wars (Disc 1) (Igrovoj) Войны Сакуры | PC | | Original | | | |
| Sakura Wars (Disc 2) Войны Сакуры | PC | | Original | | | |
| Sakura Wars 2 Войны Сакуры 2 | PC | | Original | | | |
| Salad Days: Shin Seitouha Ren'ai Typing サラダデイズ 新・正統派恋愛タイピング | PC | | Original | | | |
| Salammbo (Disc 1) Саламмбо | PC | | 1C: Kollekciya igrushek | | | |
| Salammbo (Disc 2) Саламмбо | PC | | 1C: Kollekciya igrushek | | | |
| Salaryman Kintarou: Dai-3-kan Touhoku Dotou-hen サラリーマン金太郎:第3巻東北怒涛篇 | PC | | Original | | | |
| Salzburg no Majo ザルツブルグの魔女 | PC | | Original | | | |
| Sam & Max Hit the Road | PC | | Softgold, Rerelease | | | |
| Sam & Max Hit the Road | PC | | Collezione CD-Rom by C.T.O. | | | |
| Sam & Max: Beyond Time and Space | PC | | Original | | | |
| Sam & Max: Season 1 Сэм и Макс: Первый Сезон | PC | 1.0 | Original | | | |
| Sam & Max: Season One Sam & Max: Első Évad | PC | 1.0.0.1 | Original | | | |
| Sam & Max: Season One | PC | | Covermount | | | |
| Sam & Max: Season One | WII | | Beta | | | |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: Sezon 1 | PC | 1.0 | Original | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| Samanta Svift. Tajna Atlantidy' Саманта Свифт. Тайна Атлантиды | PC | 1.3 | Original | | | |
| Samanta Svift. Tajna Zolotogo Prikosnoveniya Саманта Свифт. Тайна Золотого Прикосновения | PC | 1.2 | Original | | | |
| Samantha Swift and the Roses of Athena | PC | | Play + Smile | | | |
| Samba World Cup | ACD | | Original | | | |
| Same Game FX | PC-FX | | Bundled with PC-FXGA | | | |
| Sammy's Science House 泡泡蟲的實驗室 | PC | 1.0.0.0 | Original | | | |
| Sammy's Science House | PC | 1.0 | Original | | | |
| Sammy's Science House | PC | 1.1 | Original | | | |
| Samorost 2 | PC | | Machinarium + Samorost 2 | | | |
| Samorost 2: Zvezdanutoe priklyuchenie (Igrovoj disk) Саморост 2. Звезданутое приключение | PC | | Podarochnoe izdanie | | | |
| Samurai Shodown | MCD | | Bundled with Magazine (Demo) | | | |
| Samurai Shodown | 3DO | | Original | | | |
| Samurai Shodown II Samurai Spirits | PC | | All You Can Play: 10 Action-Games | | | |
| Samurai Warriors 2 | PC | | Original | | | |
| Samurai Warriors: Katana | WII | | Beta | | | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | | |
| The San Diego Zoo Presents... The Animals! | 3DO | | Original | | | |
| Sanae-chan wa Torawarete Shimatta! (Disc 1) さなえチャンは囚われてしまった! | PC | | Original | | | |
| Sanarara サナララ | PC | | Original | | | |
| Sanctum 2 サンクタム2 | PC | | Original | | | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sango 2 制霸三國貳 | PC | 1.0 | Original | | | |
| Sangokushi Gekiten 三國志撃天 | PC | | Original | | | |
| Sangokushi Koumeiden 三國志孔明傳 | PC | | Original | | | |
| Sangokushi Tai Sen: Dairyuusei 三国志戴閃-大流星- | PC | 1.01 | Original | | | |
| Sangokushi X Power-Up Kit 三國志Ⅹ パワーアップキット | PC | 1.2.0.1 | Sourcenext Selection | | | |
| Sangokushi: Returns 三國志 リターンズ | PC | 1.0 | Kikan Gentei Hatsubai | | | |
| Sanguo Mahjong Fengyun 三國麻將風雲 | PC | | Original | | | |
| Sanguo Qunyingzhuan 三國群英傳 | PC | 1.00 | Original | | | |
| Sanguo Qunyingzhuan II (Disc 1) 三國群英傳Ⅱ | PC | 1.0 | Rerelease | | | |
| Sanguo Qunyingzhuan III (Disc 1) (Anzhuangpan) 三国群英传Ⅲ | PC | 1.06C | Original | | | |
| Sanguo Qunyingzhuan III (Disc 2) (Youxipan) 三国群英传Ⅲ | PC | 1.06C | Original | | | |
| Sanguo Qunyingzhuan IV (Disc 1) (Anzhuangpan) 三国群英传Ⅳ | PC | 1.00 | Original, Luanshi-Yingxiongbao | | | |
| Sanguo Qunyingzhuan IV (Disc 2) (Youxipan) 三国群英传Ⅳ | PC | 1.00 | Original, Luanshi-Yingxiongbao | | | |
| Sanguo Qunyingzhuan IV (Disc 3) (Yinyuepan) 三国群英传Ⅳ | PC | | Luanshi-Yingxiongbao | | | |
| Sanguo Qunyingzhuan IV Ziliao Sheding 三国群英传Ⅳ 资料设定 | PC | | Bundled with Book | | | |
| Sanguo Yingxiongzhuan 三国英雄传 | PC | | Shiji Zhencangban | | | |
| Sanguo Zhi Xinghai Fengyun (Disc 1) 三國之星海風雲 | PC | | Original | | | |
| Sanguo Zhi Xinghai Fengyun (Disc 2) 三國之星海風雲 | PC | | Original | | | |
| Sanguozhi Fengyun Zaiqi 三國志·風雲再起 | PC | 1.2 | Original | | | |
| Sanguozhi Internet Wangjiwangluban 三國志 Internet 網際網路版 | PC | 1.01 | Original | | | |
| Sanguozhi IV 三國志Ⅳ | PC | | Original | | | |
| Sanguozhi IX (Anzhuangpan) 三国志Ⅸ | PC | 1.0 | Original | | | |
| Sanguozhi IX (Youxipan) 三国志Ⅸ | PC | 1.0 | Original | | | |
| Sanguozhi V 三国志Ⅴ | PC | 1.0 | Baibian Zhenbaoxiang 2 | | | |
| Sanguozhi VII 三國志Ⅶ | PC | 1.0 | Original | | | |
| Sanguozhi VIII 三国志Ⅷ | PC | 1.0 | Original | | | |
| Sanguozhi X (Anzhuangpan) 三国志Ⅹ | PC | 1.0 | Original | | | |
| Sanguozhi X (Youxipan) 三国志Ⅹ | PC | 1.0 | Original | | | |
| Sanitarium (Disc 1) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 1) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) Шизариум | PC | 1.01 | Rerelease | | | |
| Sanitarium (Disc 2) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium (Disc 3) Шизариум | PC | 1.01 | Original | | | |
| Sanitarium | PC | | Demo | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitary Podzemelij Санитары Подземелий | PC | | Original, 1C: Kollekciya igrushek | | | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Sanjieyu II: Zhenai Bu si (Disc 1) 三界諭II真愛不死 | PC | 2.0 | Original | | | |
| Sanjieyu II: Zhenai Bu si (Disc 2) 三界諭II真愛不死 | PC | 2.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 1) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: Sacred Ground (Disc 2) | PC | 1.0 | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Saru Suberi サルすべり | PC | | Original | | | |
| SAS: Secure Tomorrow SAS: A Biztonságos Holnapért | PC | 1.0 | Original | | | |
| SAS: Secure Tomorrow | PC | | Covermount | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | eXtra Klasyka XK HIT | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | Original | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | eXtra Klasyka Next | | | |
| SAT.1 Swing | PC | | Original | | | |
| Satazius Next サタゼウスネクスト | DC | 1.000 | Unlicensed | | | |
| Satomi: Yami no Kyouzou SATOMI 闇の鏡像 | PC | | Original | | | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Savage Arena | PC | | Dixons | | | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
| Savage: The Battle for Newerth | PC | 1.0 | Original | | | |
| Savage: The Ultimate Quest for Survival | PC | 1.0 | | | | |
| Save Planet Polluto | PC | 1.0 | Original | | | |
| Saw Пила | PC | | Original | | | |
| Say What You Want | CDI | | Original | | | |
| Sayma | PC | | Original | | | |
| Sayonara さよなら 体験版 | PC | | Taikenban | | | |
| SBK 08: Superbike World Championship | PC | | Covermount | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 1) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 2) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Scacchi 3D | PC | | Microforum | | | |
| Scania Truck Driving Simulator: The Game | PC | 1.0.0 | Green Pepper | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 1) | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 2) | PC | | Press Kit | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| Scenariomania Scenariomania Vol. 1 | PC | | Original | | | |
| The Scene Archive: 1988-1998 | ACD | | Original | | | |
| Scene Storm | ACD | | | | | |
| Schach & Matt | PC | | Original | | | |
| Schach & Matt 2 | PC | | Original | | | |
| Der Schatz von El Dorado | PC | | Original | | | |
| Schiene & Strasse: Der 3D-Transport-Manager: 1820-2020 | PC | | Original | | | |
| Schizm II: Kameleon (Disc 2) | PC | | Original | | | |
| Schizm II: Kameleon (Disc 3) | PC | | Original | | | |
| Schizm: Mysterious Journey (Seite A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Seite B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | | Original | | | |
| Schizm: Mysterious Journey (Side A) | PC | Build 744 | Original | | | |
| Schizm: Mysterious Journey (Side B) | PC | Build 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey | PC | 0.99 | Playable Demo | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Die Schlaue Bande: 5. Klasse Lernsystem | PC | | Original | | | |
| Die Schlaue Bande: 6. Klasse Lernsystem | PC | | Original | | | |
| Schleichfahrt | PC | | Original, Classics | | | |
| Schleichfahrt | PC | | Original | | | |
| Die Schlümpfe: Farben und Formen | PC | | Original | | | |
| Schoenbrunn | PHOTO-CD | | Original | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| School Days スクールデイズ | PC | 1.1.1.0 | Renewal Package | | | |
| Schrottplatz-Simulator 2011 | PC | | Original | | | |
| Das Schwarze Auge: Drakensang | PC | | Original, Limited Collector's Edition | | | |
| Das Schwarze Auge: Drakensang | PC | 1.11 | Software Pyramide | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Phileassons Geheimnis | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Platinum Edition | PC | | Original | | | |
| Das Schwarze Auge: Schatten über Riva | PC | | All You Can Play: Adventure & Fantasy | | | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Original | | | |
| SCI Media Kit: Version: 2 | PC | | Press Kit | | | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| The Sci-Fi Collection | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Science & Nature: Elements Science 1: Elements | ARCH | 1.00 | Original | | | |
| Science & Nature: Materials Science Series II: Materials | ARCH | 1.00 | Original | | | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Blaster Jr. | PC | | Original | | | |
| Science: Electricity and Magnetism: Secondary Edition Science 3: Electricity and Magnetism | ARCH | 1.0 | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | Original | | | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Priklyucheniya v gorode prizrakov Скуби-Ду! Приключения в городе призраков | PC | | 1C: Igroteka | | | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| Scorcher | PC | | Original | | | |
| Score 4 | PC | | Original | | | |
| Scotland Yard | PC | | Original | | | |
| Scrabble Interactive: 2003 Edition | PC | | Original | | | |
| Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | Screamer Injection | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer 2 | PC | | eXtra Klasyka | | | |
| Screamer 4x4 | PC | | Covermount | | | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
| Screen Club: Pocket Monsters スクリーンクラブ ポケットモンスター | PC | | Original | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited (Asset Disc) | PC | | Press Kit | | | |
| The Scroll | PC | | | | | |
| Scudetto 2 | PC | 1.48 | CD-ROM Classic Collection 3 | | | |
| SD Gundam: GGeneration SD 건담: G-제네레이션 | PC | 1.0.0.1 | Original | | | |
| SD Media Launcher for GameCube / Wii SDメディアランチャー Wii用/GC用 | GC | | Unlicensed | | | |
| Sea Dogs | PC | 1.06 | Green Pepper | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
| Sea Dogs: Piraci | PC | 1.06 | Original | | | |
| Sea Plane Adventures Sea Plane Adventures for FS2002/2004 | PC | | Original | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Seashore Life | ARCH | 1.0 | Original | | | |
| Second Sight | PC | | 1C: Kollekciya igrushek | | | |
| Le Secret du Templier | MAC | 1.0 | Covermount | | | |
| Secret Files: Il Mistero di Tunguska | PC | 1.00 | Covermount | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| Secret of Video Architecture X68000画面表示仕様の秘密 | X68K | | Original | | | |
| Secret Service: Wydanie Specjalne Alone in the Dark | PC | | | | | |
| Secret Weapons of the Luftwaffe | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| The Secrets of Da Vinci: Il Manoscritto Proibito (Disc 1) | PC | 1.02 | Original | | | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 2) | PC | 1.02 | Original | | | |
| Secrets of the Dark: Der finstere Berg | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section 8: Prejudice | PS3 | 01.00 | Beta | | | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Sega Bass Fishing 钓鱼高手 | PC | 1.0 | Original | | | |
| Sega CD Demo | MCD | | Prototype | | | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega GT Online | XBOX | | Beta | | | |
| Sega Hard Historia セガハードヒストリーア | PC | | Book Bundle | | | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Rally (Uaktualnienie Wersji Polskiej) | PC | | Original, TopSeller | | | |
| Sega Rally | PC | 3.2.0.3 | Original, TopSeller | | | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | | |
| Sega Touring Car Championship 世嘉巡回车大赛 | PC | | Original | | | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| SegaKara for PC セガカラ for PC | PC | 4.0.100 | Original | | | |
| Seikai no Senki 星界の戦旗 | PC | | Original | | | |
| Seinarukana: The Spirit of Eternity Sword 2 聖なるかな ーThe Spirit of Eternity Sword 2ー | PC | | Special Package | | | |
| Sekai no Subete: Remind of You 世界ノ全テ -remind of you- | PC | 1.0.0.0 | Renewal Package Ban | | | |
| Sekai Saikyou Ginsei Igo 2 世界最強銀星囲碁2 | PC | 3.0 | Yuuyuu 1,980-yen | | | |
| Self Selling Disc | CDI | 01 | Original | | | |
| Self Selling Disc | CDI | 3.1 | | | | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Sem' Samuraev (Disc 1) Семь Самураев | PC | | Original | | | |
| Sem' Samuraev (Disc 2) Семь Самураев | PC | | Original | | | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! Harukaze no Shou 戦国美少女絵巻 空を斬る!! ~春風の章~ | PC | | Original | | | |
| Senha N. 1 | PC | | | | | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc 戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senkaku Mondai o Yatchimasu 2 尖閣問題を殺っちます2 | PC | | Original | | | |
| Sensei 2 Запретное влечение | PC | | Original | | | |
| Sensible Soccer | MCD | | Bundled with Magazine (Playable Demo - Mega Power Disc 5, Demo) | | | |
| Sensible Soccer 2006 | PC | 0.0.0.1 | Original | | | |
| Sensible World of Soccer | PC | 1.0 | Original | | | |
| Sentient | PC | 1.4.0.124 | Original | | | |
| Sentient | PC | | Original | | | |
| Sentimental Graffiti 2 (Disc 1) 青澀寶貝2:青澀之戀 | PC | 1.00 | Original | | | |
| Sentimental Graffiti 2 (Disc 2) 青澀寶貝2:青澀之戀 | PC | 1.00 | Original | | | |
| Sentinel: Strazh vremeni (Disc 1) Sentinel: Страж времени | PC | 1.0 | Original | | | |
| Sentinel: Strazh vremeni (Disc 2) Sentinel: Страж времени | PC | 1.0 | Original | | | |
| Sento Monogatari: Sono I 「占都物語」 そのI | PC | | Original | | | |
| Septerra Core: Legacy of the Creator 赛普特拉战记 | PC | 1.02 | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00I | Covermount | | | |
| Serdce Vechnosti Сердце Вечности | PC | 1.0 | Original | | | |
| Serious Sam 3: BFE | PC | 1.0 | Original | | | |
| Serious Sam HD: The Second Encounter Serious Sam HD: Второе Пришествие | PC | | Original | | | |
| Serious Sam II | PC | | Original | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | Green Pepper | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | Covermount | | | |
| Serious Sam II Крутой Сэм II | PC | 2.066.00 : 59775 | 1C: Kollekciya igrushek | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam: Drugie Starcie Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
| Serious Sam: Pierwsze Starcie Serious Sam: The First Encounter | PC | 1.00b | Original | | | |
| Serious Sam: The First Encounter 英雄萨姆 | PC | 1.00 | Original, Zhima Kai Men | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Serious Sam: The First Encounter | PC | 1.05 | Gold Edition | | | |
| Serious Sam: The First Encounter | PC | 1.00a | Covermount | | | |
| Serious Sam: The First Encounter Крутой Сэм: Первая Кровь | PC | 1.00b | 1C: Kollekciya igrushek | | | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| Serious Sam: The First Encounter | PC | 1.02 | Bundle Version Gainward OEM | | | |
| Serious Sam: The Second Encounter 英雄萨姆2 | PC | 1.05 | Original | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original, TakeAdvantage | | | |
| Serious Sam: The Second Encounter | PC | 1.07 | Gold Edition, Covermount | | | |
| Serious Sam: The Second Encounter | PC | | Rerelease | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Software Pyramide | | | |
| Serious Sam: The Second Encounter Крутой Сэм: Второе пришествие | PC | 1.05 | 1C: Kollekciya igrushek | | | |
| Serp i Molot Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 1) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 2) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 3) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | 3DO | | Original | | | |
| Sethi und das Geheimnis der Neandertaler | PC | | Rerelease | | | |
| Sethi: Abenteuer im Mittelalter National Geographic: Sethi: Abenteuer im Mittelalter | PC | | Original | | | |
| The Settlers II | PC | | Demo | | | |
| The Settlers II | PC | 1.51 | Strefa Niskich Cen | | | |
| The Settlers II: 10-lecie The Settlers II: 10th Anniversary | PC | | eXtra Klasyka Next | | | |
| The Settlers II: Nowe Misje | PC | 1.51 | Strefa Niskich Cen | | | |
| Settlers II, The: Veni, Vidi, Vici | PC | 1.51 | Rerelease | | | |
| Settlers II, The: Veni, Vidi, Vici | PC | 1.51 | PC Best Buy | | | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| The Settlers III (Disc 1) 工人物語III | PC | 1.23 | Original | | | |
| The Settlers III (Disc 1) | PC | 0.0.0.91 | Original | | | |
| The Settlers III (Disc 1) | PC | 0.0.0.123 | | | | |
| The Settlers III (Disc 2) | PC | 0.0.0.91 | Original | | | |
| The Settlers III: Gold Edition (Disc 1) | PC | 1.25.0.125 | Original | | | |
| The Settlers III: Gold Edition (Disc 2) | PC | 1.25.0.125 | Original | | | |
| The Settlers III: Nowe Misje (Disc 1) | PC | 1.25.0.125 | | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | 1.25.0.125 | | | | |
| The Settlers III: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers IV 工人物语IV | PC | 1.09.876 | Original | | | |
| The Settlers IV | PC | 1.06.815 | Original | | | |
| The Settlers IV ザ・セトラーズ4 | PC | 2.04.1090 | | | | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Original | | | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Gold Edition | | | |
| The Settlers IV: Złota Edycja | PC | | Nowa eXtra Klasyka | | | |
| The Settlers IV: Złota Edycja | PC | 2.50.1516.0 | eXtra Klasyka Next | | | |
| The Settlers IV: The Trojans and the Elixir of Power The Settlers IV: A Trójaiak és a Hatalom Elixírje | PC | 2.50.1508 | Original | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers: Dziedzictwo Królów The Settlers: Heritage of Kings | PC | | eXtra Klasyka Next | | | |
| The Settlers: Heritage of Kings (Disc 1) The Settlers: Dědictví Králů | PC | 1.03.0190 | Original | | | |
| The Settlers: Heritage of Kings (Disc 2) The Settlers: Dědictví Králů | PC | 1.03.0190 | Original | | | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Covermount | | | |
| The Settlers: Nasledie Korolej The Settlers: Наследие Королей | PC | 1.03.0190 | Original | | | |
| The Settlers: Nasledie korolej (Disc 1) The Settlers: Наследие королей | PC | 1.03.0190 | Original | | | |
| The Settlers: Nasledie korolej (Disc 2) The Settlers: Наследие королей | PC | 1.03.0190 | Original | | | |
| The Settlers: Rascvet Imperii The Settlers: Расцвет империи | PC | | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original | | | |
| Setup Utility for DTL-H1500 (Version 1.1) | PSX | | Original | | | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Seven Kingdoms | PC | | Play the Games Vol. 1 | | | |
| Seven Kingdoms II: The Fryhtan Wars 七国演义II:群魔乱舞 | PC | 1.0 | Rerelease | | | |
| Seven Kingdoms: Ancient Adversaries | PC | 2.00 | Original, 2in1 Pack | | | |
| Seven Kingdoms: Artwork | MAC | | Art Assets | | | |
| Seven Years War 2 決戰王朝 | PC | 1.090ER | Original | | | |
| Seven Years War 2 + Joseonui Bangyeok 임진록 2 + 조선의 반격 | PC | | Hapbon | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Disc 2) 第七封印 魔神苏醒第七封印:魔神甦醒 | PC | 2.0.0.0 | Original, Limited Edition | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 1) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 2) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 3) 第七封印:魔神甦醒 | PC | | Original | | | |
| Sewer Shark | 3DO | | Original | | | |
| Sex | 3DO | | Original | | | |
| Sex Sensou: Aiaru H wa Kinshi desu! H-na Hiyakeato Patch SEX戦争~愛あるHは禁止ですっ!~Hな日焼け跡パッチ | PC | | Original | | | |
| Sexy Bytes: Housewives 2 | PHOTO-CD | | Original | | | |
| Sexy Bytes: Lacquer & Leather | PHOTO-CD | | Original | | | |
| Sexy Bytes: Office Sex | PHOTO-CD | | Original | | | |
| Sexy Bytes: Outside Dreams | PHOTO-CD | | Original | | | |
| Sexy Bytes: Rolling Mountains | PHOTO-CD | | Original | | | |
| Sexy Bytes: Studio Girls 1 | PHOTO-CD | | Original | | | |
| Sexy in the Hawaii: Nice Gal Hawaii-hen Sexy in The Hawaii ~ナイス・ギャル ハワイ編~ | FMT | | Original | | | |
| Sezon oxoty Сезон охоты | PC | | Original | | | |
| Sfera II: Arena Сфера II: Арена | PC | | Original | | | |
| Sfera: Materik Vlasti Сфера: Материк Власти | PC | | 1C: Kollekciya igrushek | | | |
| Sfera: Prokljatie Giperiona Сфера: Проклятие Гипериона | PC | | 1C: Kollekciya igrushek | | | |
| Sfida nella Piramide! | PC | | Evviva! Software | | | |
| Shade: L'Ira degli Angeli | PC | 1.2 | EXA Games Premium, Covermount | | | |
| Shade: Wrath of Angels Shade: Hněv Andělů | PC | 1.01 | Original | | | |
| Shade: Wrath of Angels (Press Disc) | PC | | Press Kit | | | |
| Shadoan | PC | | Interactive Preview | | | |
| Shadow Company: Left for Dead | PC | | Original | | | |
| Shadow Fight (Disc 1) Бой с тенью | PC | | Original | | | |
| Shadow Fight (Disc 2) Бой с тенью | PC | | Original | | | |
| Shadow Fighter | CD32 | | Original | | | |
| Shadow Hearts: Special Disc SHADOW HEARTS スペシャルディスク | PC | | Hibaihin | | | |
| Shadow Man | PC | | Covermount | | | |
| Shadow Man | PC | | Demo | | | |
| Shadow of Memories | PC | | Original | | | |
| The Shadow of the Third Moon | ACD | 1.1 | Original | | | |
| Shadow Vault: Demos and Materials | PC | | Original | | | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original | | | |
| Shadow Watch | PC | | Original | | | |
| Shadow Watch | PC | 1.0 | Original | | | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| Shadowbane | PC | | Taikenban | | | |
| ShadowCaster | PC | | Original | | | |
| Shadowgrounds | PC | | Linux (LGP) | | | |
| Shadowgrounds Survivor | PC | finland 1.00 | Special Edition | | | |
| Shadowgrounds Survivor | PC | | Linux (LGP) | | | |
| Shadowgrounds: Survivor | PC | 1.00 | Gry dla Ciebie | | | |
| Shadowlands | PC | | Original, 10 Pack CD-ROM Series, Action CD-ROM 5 Pak | | | |
| Shadowrun Returns | PC | 1.2.0 | Original | | | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shaftdiver | PC | 0.1 | Taikenban | | | |
| Shakii il Lupo Shakii the Wolf | PC | | Microforum | | | |
| Shakii the Wolf | PC | | Original | | | |
| Shamrock Spring '97 Shamrock Spring '97 Demo Disk | PC | | | | | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shan Yu E 善與惡 | PC | 1.0.0.1 | Original, Quanzhongwen Wanzhengban | | | |
| Shan Yu E: Shenshoudao 善與惡:神獸島 | PC | 1.23 | Quanzhongwen Wanzhengban | | | |
| Shangdi 上帝 | PC | 1.00 | Game Box Rerelease | | | |
| Shangdi Ye Fengkuang 上帝也疯狂 | PC | 1.01 | Original | | | |