Region | Title | System | Version | Edition | Languages | Serial | Status |
| Syndicate Plus | PC | | CD-ROM Classics | | E2825CCD | |
| Supercars International | PC | | Hit Squad | | HITSQDUK 026 | |
| Superbike 2001 | PC | | Original, EA Classics | | EAX08903308D, EAX08903632D1 | |
| Supaplex | PC | | Action Replay | | | |
| Stunt Driver | PC | 1.1 | Action Sixteen | | | |
| Stonekeep | PC | 1.2 | Original | | CD-ICD-045-0 | |
| Star Trek: Judgment Rites | PC | | White Label, White Label: Doubles | | | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | White Label, White Label: Doubles, Star Trek: Federation Compilation | | CD-ICD-301-0 | |
| Star Legions Trevor Sorensen's Star Legions | PC | 1.0 | Action Replay | | | |
| Star Control Collection | PC | | Original, Rerelease | | 7094 | |
| Stack Up | PC | | Original | | | |
| Sonic Riders | PC | 1.0 | Sonic PC Collection | | SEGA-PC051, SEGA-PC051-EU | |
| Sonic Mega Collection Plus | PC | 1.00.0000 | Sonic PC Collection | | SEGA-PC033, SEGA-PC033-EU | |
| Sonic Heroes (Disc 2) | PC | | Sonic PC Collection | | SEGA-PC008/2, SEGA-PC008/2-EU | |
| Sonic Heroes (Disc 1) | PC | | Sonic PC Collection | | SEGA-PC008/1, SEGA-PC008/1-EU | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.009 | Sonic PC Collection | | SEGA-PC002-EU, SEGA-PC002/2-EU | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.009 | Sonic PC Collection | | SEGA-PC002-EU, SEGA-PC002/1-EU | |
| Smok Wawelski | PC | | Covermount | | SELL 0132 | |
| Slam Tilt | PC | | Original | | | |
| Skoki Narciarskie 2005 | PC | | Covermount | | | |
| Skoki Narciarskie 2004 | PC | | Covermount | | | |
| Skoki Narciarskie 2003: Polski Orzeł: Złota Edycja | PC | 2.1.G | Covermount | | | |
| Skoki Narciarskie 2003: Polski Orzeł | PC | 0.1 | Covermount | | | |
| Skoki Narciarskie 2001: Polski Zwycięzca | PC | 1.03e | Covermount | | | |
| Shadoworlds | PC | | Buzz | | | |
| Shadowlands | PC | | Original, 10 Pack CD-ROM Series, Action CD-ROM 5 Pak | | | |
| Sensible World of Soccer '96/'97 | PC | 2.0 | Original | | | |
| Sensible Soccer: European Club Edition | PC | | Original | | | |
| Sega Rally Championship PC | PC | 2.11 | Fair Game, Grabit | | FG-1282, GDL016 | |
| Sega Rally 2 (Disc 2) (Play Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-2 | |
| Sega Rally 2 (Disc 1) (Install Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-1 | |
| Sega Rally | PC | 3.2.0.3 | Original, TopSeller | | | |
| Sega Rally (Uaktualnienie Wersji Polskiej) | PC | | Original, TopSeller | | | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge The Monkey Island Bounty Pack: The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | 1.0 | LucasArts Classics: The Monkey Island Bounty Pack | | 3000012.101.UK | |
| Sam & Max Hit the Road | PC | 2.0 | LucasArts Classic | | 41117.101.UK | |
| Syberia: Złota Edycja | PC | 1.0 | Kolekcja Klasyki | | CENEGA 396/PCDVD-ROM/2006 | |
| Sword of the Samurai | PC | 445.01 | Hit Squad: Regenerator | | REGEN019 | |
| Świat Kangurka Kao | PC | | Original | | 503/DVD/2006 | |
| Supreme Snowboarding | PC | 1.033 | Original | | SUPSNOPCFGDEINSF | |
| Supreme Snowboarding | PC | 1.033 | Sold Out Software | | | |
| SuperKarts | PC | 1.01 | White Lines: Don't Do It - 3 Game Driving Pack | | | |
| Superbike 2001 (Documents) | PC | | EA Classics | | EAX08903632D2 | |
| Super Yatzy / Dizzy Dice Double Fun Pack Vol. 3 | PC | | Original | | | |
| Super Street Fighter II Turbo | PC | 1.0 | Rerelease | | | |
| Super Stardust 96 | PC | | CD-ROM 5 Mark-Reihe | | Art.-Nr. 2857 | |
| Super Space Invaders / Football Manager 2 & 3 | PC | | CD-ROM 5 Mark-Reihe | | | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Stormovik: SU-25 Soviet Attack Fighter Stormovik | PC | | Hit Squad / Euro Power Pack | | HITDANCD001 | |
| Steel Thunder: American Battle Tank Simulation Steel Thunder | PC | | Telstar Fun & Games | | TFGD 2177/2 | |
| Stack Up / Arcade Fruit Machine Double Fun Pack: Volume 1 | PC | | Original | | | |
| Sport Image: World Cup 1994 1994 International Soccer | PC | 2.0 | Soccer Superstars | | | |
| Split Screen Soccer Managers | PC | | Soccer Superstars | | | |
| Spirit of Excalibur | PC | | Original | | CDAC 013900 | |
| Śpiąca Królewna | PC | | Covermount | | SELL 0161 | |
| Speedy Eggbert II Speedy Eggbert 2 | PC | 1.0 | Original | | | |
| Speedy Eggbert | PC | 1.1 | Original | | 02-9703-10 | |
| Special Forces | PC | 1.00 | Hit Squad: Regenerator | | REGEN020 | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
| SpaceHaste 2 SpaceHaste | PC | 1.32 | TopWare Just 4Fun | | | |
| Soccer Team Manager | PC | | Soccer Superstars | | | |
| Soccer Kid Soccer Kid: Feets of Fury!! | PC | | Original | | D134 | |
| Snakebyte Special Spiele | PC | | Original | | Kat.-Nr. 6007 | |
| Słownik Obrazkowy Języka Niemieckiego | PC | | Covermount | | SELL 0149 | |
| Słownik Obrazkowy Języka Angielskiego | PC | | Covermount | | SELL 0145 | |
| SleepWalker | PC | | TopWare Just 4Fun | | | |
| SleepWalker | PC | | Grabit | | GDL061 | |
| Slam 'n Jam '96 featuring Magic & Kareem | PC | | Original | | 76896427322 | |
| Skrzaty: Leśne Przygody | PC | 1.20 | Original | | | |
| Skoki Narciarskie 2006: Edycja Olimpijska | PC | | Covermount | | | |
| Skoki Narciarskie 2004: Wersja 2.0 | PC | 2.0 | Covermount | | | |
| Skoki Narciarskie 2002: Polskie Złoto | PC | 1.44 | Covermount | | | |
| Skaut Kwatermaster CD | PC | | Covermount | | SELL 0249 | |
| Simon the Sorcerer Double Pack | PC | | Original | | | |
| Silmarils Collection | PC | 1.6 | Just for Games: Just for Gamers | | JFG10-SICO-OBL | |
| Silent Service II | PC | 457.01 | Action Sixteen | | | |
| Sid Meier's Railroad Tycoon Deluxe | PC | 2.0 | Sold Out Software | | | |
| Sid Meier's Pirates! | PC | 1.0.2.0 (30927) | Kolekcja Klasyki | | CENEGA 564/PCDVD-ROM/2007 | |
| Sid Meier's Covert Action | PC | 447.01 | Hit Squad: Regenerator | | REGEN014 | |
| Shuttle: The Space Flight Simulator Shuttle | PC | 1.01 | Hit Squad / Euro Power Pack | | HITDANCD015 | |
| Sheep | PC | 1.0.0.1 | Grabit | | GDL090 | |
| Shanghai: Second Dynasty | PC | 1.0 | Original | | 1000930.101.UK | |
| Shanghai: Dynasty | PC | 1.0 | Original | | 1000053.101.UK | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Sensible World of Soccer: European Championship Edition | PC | 1.2 | White Label | | | |
| Sega Mega Drive Classic Collection: Złota Edycja | PC | 1.0.019 | Platynowa Kolekcja | | P_37010_04A_PL | |
| Search and Rescue Air Rescue | PC | | Grabit | | GDL024 | |
| Sea War Sea War: Entscheidungsschlacht im Pazifik | PC | | Original | | SPI 023 | |
| Sea Dogs: Piraci | PC | 1.06 | Original | | | |
| The Scottish Open: Virtual Golf | PC | | Euro Power Pack | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | eXtra Klasyka XK HIT | | | |
| Safecracker | PC | | Original | | | |