Region | Title | System | Version | Edition | Languages | Serial | Status |
| Spud! (Disc 2) | PC | | Original | | | |
| Spud! (Disc 1) | PC | | Original | | | |
| Springy | PC | | Original | | | |
| Sprill: Wodne Przygody | PC | | | | | |
| Spriggan: Lunar Verse スプリガン ~ルナ・ヴァース~ | PSX | | The Preview Movie | | SLPM 80447 | |
| Spriggan: Lunar Verse スプリガン ~ルナ・ヴァース~ | PSX | | Original | | SLPS 02117 | |
| SPQR: The Empire's Darkest Hour | PC | | Original | | | |
| SPQR: The Empire's Darkest Hour | PC | | Hemming All Stars | | | |
| SPQR: The Emperor's Darkest Hour | PC | | Original | | MMICDR 5188 | |
| Spot Goes to Hollywood スポット・ゴーズ・トゥー・ハリウッド | PSX | | Original | | SLPS 00394 | |
| Spot Goes to Hollywood | SS | 1.400 | Original | | T-7001H-50 | |
| Spot Goes to Hollywood | PSX | | Original | | SLES-00330 | |
| SportzFreakz | PC | 1.0 | Original | | | |
| Sportweek Player Manager 2001 | PSX | | Original | | SLES-03569 | |
| Sportweek Player Manager 2000 | PSX | | Original | | SLES-02616 | |
| Sportsman's Paradise II | PC | 1.0 | Original | | P/N 4-19599CDSL | |
| Sports: Football | CD32 | | | | | |
| Sports Wurx 1 | PC | | Original | | CDO226 | |
| Sports Jam | DC | 1.001 | Original | | T-44304N | |
| Sports Jam スポーツ・ジャム | DC | 1.005 | Original | | HDR-0153 | |
| Sports Jam スポーツ・ジャム | NAOMI | 1.005 | Original | | GDS-0003 | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Challenge Pack 2 | PC | | Encyclopedia Games 2009-10 Deluxe Edition | | | |
| Sports Car GT | PC | 1.52US | CD-ROM Classics | | 1187207 | |
| Sports Car GT | PC | 1.52m | Bundle Version OEM | | | |
| Sports Car GT (Manuale Elettronico) | PC | | Original | | ECA430 DK2 | |
| Sports Car GT | PSX | EDC | EA Classics | | SLES-01916 | |
| Sports Car GT | PC | 1.52m | Play the Games Vol. 3 | | | |
| Sports Car GT | PC | 1.52m | EA Classics | | WWG08801952D | |
| Sports Car GT | PSX | | Original | | SLES-01915 | |
| Sportowe Zmagania bez Wysiłku i Biegania | PC | | | | | |
| Sport Image: World Cup 1994 | PC | 2.0 | SoftKey | | WCF344AE-CD | |
| Sport Image: World Cup 1994 1994 International Soccer | PC | 2.0 | Soccer Superstars | | | |
| Spooky Castle | PC | 1.0 | Original | | 11-2057-10 SPC | |
| Spokojnye igry: krug, shashki, shaxmaty, ugolki i... Спокойные игры: круг, шашки, шахматы, уголки и... | PC | | Original | | | |
| Split Screen Soccer Managers | PC | | Soccer Superstars | | | |
| Splatterhouse スプラッターハウス | FMT | | Ving Vol. 13 | | HMD-146 | |
| Splatter Master | PS2 | 1.01 | Original | | SLES-53368 | |
| Splatt! | PC | | Original | | | |
| Splashdown: Rides Gone Wild | PS2 | 1.00 | Demo | | SLUS 29054 | |
| Spirou | PC | | Promo | | SPIROM65511 | |
| Spirits of Mystery: Amber Maiden | PC | | BlackLime Games | | BLG022/D | |
| Spirit of Speed 1937 | DC | 1.001 | Original | | T-8118N | |
| Spirit of Speed 1937 スピリット オブ スピード 1937 | DC | 1.000 | Original | | T-8102M | |
| Spirit of Speed 1937 | PC | 1.0.13 | Game-Hits 1 | | | |
| Spirit of Speed 1937 | DC | 1.002 | Original | | T-8117D-50 | |
| Spirit of Excalibur | PC | | Original | | CDAC 013900 | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi: Roy Ver. Spinnaker Typing Collection 鋼の錬金術師 ロイver. | PC | | Original | | | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi Spinnaker タイピングコレクション 鋼の錬金術師 | PC | 1.01 | Original | | | |
| Spinnaker Desktop Collection: Hagane no Renkinjutsushi: Honoo SPINNAKER DESKTOP COLLECTION 鋼の錬金術師 焔 | PC | | Original | | | |
| Spinnaker Desktop Collection: Hagane no Renkinjutsushi SPINNAKER DESKTOP COLLECTION 鋼の錬金術師 | PC | | Original | | | |
| Spinnaker Chara Colle: Hagane no Renkinjutsushi Vol. 5: Calendar Spinnaker キャラコレ 鋼の錬金術師 Vol.5 カレンダー | PC | | Original | | | |
| Spinnaker Chara Colle: Hagane no Renkinjutsushi Vol. 4: Nengajou Spinnaker キャラコレ 鋼の錬金術師 Vol.4 年賀状 | PC | | Original | | | |
| Spinnaker Chara Colle: Hagane no Renkinjutsushi Vol. 3: Letter Set Spinnaker キャラコレ 鋼の錬金術師 Vol.3 レターセット | PC | | Original | | | |
| Spinnaker Chara Colle: Hagane no Renkinjutsushi Vol. 2: CD/DVD Label Spinnaker キャラコレ 鋼の錬金術師 Vol.2 CD/DVD ラベル | PC | | Original | | | |
| Spinnaker Chara Colle Series: Hagane no Renkinjutsushi Vol. 1: Name Seal Spinnaker キャラコレシリーズ 鋼の錬金術師 Vol.1 ネームシール | PC | | Original | | | |
| Spinnaker Chara Colle Calendar: Hagane no Renkinjutsushi Spinnaker キャラコレカレンダー 鋼の錬金術師 | PC | | Original | | | |
| Spine Sense: The Interactive Back Protection Program | CDI | | Original | | | |
| Spin Busta | PC | 1.0 | Original | | GS0003 | |
| Spike: The Hedgehog | PC | | Covermount | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Original | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Dice | | DCG 012965 | |
| Spike: The Hedgehog | PC | 1.0.0.1 | | | APWCDR1033 | |
| Spielen mit Freundin | PC | | Original | | | |
| Spielekiste 2 | ACD | | Original | | | |
| Spiele für Windows 7, XP & Vista | PC | | Software Pyramide | | | |
| Spielbare Cheats Volume 27 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 26 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 25 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 24 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 23 | PS2 | 1.10 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 22 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 21 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 20 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 19 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 18 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 17 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 16 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spiel des Lebens | PC | | Original | | | |
| Spider: The Video Game | PSX | | Original | | SLES-00682 | |
| Spider: The Video Game | PSX | | Original | | SLES-00681 | |
| Spider: The Video Game | PSX | | Original | | SLES-00117 | |
| Spider-Man: The Sinister Six Spider-Man: Die Gnadenlosen Sechs | PC | | Original | | | |
| Spider-Man: Kampen om Evigt Liv | PC | | Book Bundle | | CDJ 8002 | |
| Spider-Man: Angriff der Super-Schurken | VFLASH | | Original | | 093064(GER) | |
| Spider-Man Databank | PC | | Original | | | |
| Spider-Man 2: The Game | PC | | Covermount | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.GM | |
| Spider-Man 2: La Revanche d'Electro | PSX | | Platinum | | SLES-03624 … | |
| Spider-Man 2: Enter: Electro スパイダーマン2 ~エンター:エレクトロ~ | PSX | | Original | | SLPM 87073 | |
| Spider-Man 2: Enter: Electro | PSX | | Original | | SLES-03623 | |
| Spider-Man 2 | PC | | Demo | | | |
| Spider-Man | MAC | | Original | | | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man | DC | 1.000 | Original | | T-13008N | |
| Spider-Man | PC | | Demo | | | |
| Spider-Man | PSX | | Platinum | | SLES-02890 … | |
| Spider-Man | PSX | | Platinum | | SLES-02889 … | |
| Spider-Man | PSX | | Original | | SLES-02888 … | |
| Spider-Man | PSX | | Platinum | | SLES-02887 … | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.UK | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.UK | |
| Spider-Man | DC | 1.000 | Original | | T-13011D-50 | |
| Spice World | PSX | | Original | | SCES-01234 | |
| Spice World | PSX | | Original | | SCES-01232 | |
| Spice World | PSX | | Original | | SCES-01231 | |
| Spice World | PSX | | Preview Version | | SCES-00883 | |
| Spice World | PSX | | Review | | | |
| Śpiąca Królewna | PC | | Covermount | | SELL 0161 | |
| Sphinix Gold | PC | | Original | | ROK 04 Art.-Nr. 6623 | |
| Sphere Racer | PC | | Original | | | |
| Sphere 360° | PSX | | Bundled with ASCII Sphere 360° Controller | | SLED-01711 | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| Spełnij Marzenia: Gra Piłkarska Pepsi | PC | | | | | |
| Spelvin Goolie Private Eyeball Spelvin Goolie Private Eyeball: The World's Greatest Left-Handed Detective | PC | 1.0 | Original | | ROW-10942 | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Speltajm: Djungelns kojigaste CD-ROM | PC | | Original | | | |
| Spells of Gold | PC | | Original | | CENEGA 163/2003 | |
| Spelling: 'SATS' Key Stage 2 | PC | 1999.12.1.1 | Original | | | |
| Spelling Home Tutor | PC | | | | | |
| SpellForce: Złota Edycja (Disc 4) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 3) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Zakon Switu (Disc 2) | PC | | | | | |
| SpellForce: The Order of Dawn: Songs of Winter SpellForce: The Order of Dawn: Songs of Winter: The Official Soundtrack to Breath of Winter | PC | | Limited Edition | | ROSPELLFOR0012LABST | |
| SpellForce: The Order of Dawn (Disc 2) | PC | | Covermount | | ROSPELLFOR0003LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) | PC | | Covermount | | ROSPELLFOR0003LAB1 | |
| SpellForce: The Order of Dawn (Disc 3) (Install CD3) | PC | | Limited Edition | | ROSPELLFOR0012LAB3 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab2 | |
| SpellForce: The Order of Dawn (Disc 2) (Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | | Limited Edition | | ROSPELLFOR0012LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab1 | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | | Limited Edition | | ROSPELLFOR0012LAB1 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Breath of Winter | PC | 1.30 | Original | | ROSPELLFOR0005LAB | |
| SpellForce: Gold Edition (Disc 3) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 2) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 1) | PC | 1.53.65731 | Original | | | |
| Spellcross: L'Ultima Battaglia | PC | | CD-ROM Classic Collection 7 | | | |
| Spellcasting: Party Pak | PC | 1.0 | Original | | | |
| Het Speelhuis van Muis | PC | | Original | | | |
| Speel Bridge 5 | PC | | Original | | | |
| Speel Bridge 4 | PC | | Original | | | |
| Speedy Zone 2 | PC | | Original | | 100-4045 | |
| Speedy Eggbert II Speedy Eggbert 2 | PC | 1.0 | Original | | | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| Speedy Eggbert | PC | 1.1 | Original | | 02-9703-10 | |
| Speedway 2000 | PC | | Original | | | |
| Speedster | PC | | Dice | | DCG 005813, DMM 005837 | |
| Speedster | PC | | Original, Argentum Collection | | | |
| SpeedRage | PC | 1.10 | 2in1 Pack | | | |
| SpeedRage (Game Disk) | PC | 1.10 | Original | | TFGD2159 | |
| SpeedRage (Slave Disk) | PC | 1.10 | Original | | TFGD2159 | |
| Speedlink Competition Pro USB: Sports Tournament Edition | PC | | Bundle Version Speedlink OEM | | SL-6603-SPORTS-EU | |
| Speedboat GP | PS2 | 1.01 | Original | | SLES-54074 | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | 0.9.9.0 | Covermount | | | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speedboat Attack | PC | 0.9.9.0 | Original | | | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Speed Thief | PC | 1.0 | Original | | | |
| Speed Mania e路狂飆 屏鵝公路篇 體驗版 | PC | | Demo | | | |
| Speed Machines | PSX | | Original | | SLES-03930 | |
| Speed Kings | PS2 | 1.00 | Original | | SLUS 20584 | |
| Speed Haste | PC | | Rerelease | | | |
| Speed Haste | PC | | Pocket Price Games | | | |
| Speed Freaks (Misc Artwork: PC-CD 2nd July '99) | PC | | Press Kit | | | |
| Speed Freak | PC | | Covermount | | | |
| Speed Devils: Online Racing | DC | 1.002 | Original | | T-17718N | |
| Speed Devils: Online Racing | DC | 1.003 | Original | | T-17713D-50 | |
| Speed Devils | DC | 1.004 | Original | | T-17702N | |
| Speed Devils | DC | 1.004 | Original | | T-17702D-50 | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Original | | Ref: 65702162 | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Busters | PC | 1.02 | Demo | | | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Covermount | | | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Ubi Soft Classique | | | |
| Speech Trainer V1.0 L10 スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Spectrobes: Beyond the Portals (Electronic Press Kit) | PC | | Press Kit | | | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Spectre VR CD | MAC | | Original | | | |
| Spectre VR | PC | 1.07wp | Ultimate Game Collection | | | |
| Spectre VR | PC | 1.05 | Original | | | |
| Spectral vs. Generation スペクトラル VS ジェネレーション | PS2 | 1.02 | Original | | SLPM 62727 | |
| Specnaz: proekt Volk (Disc 2) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: proekt Volk (Disc 1) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: Antiterror. Missija na Balkanah (Disc 1) Спецназ: Антитеррор. Миссия на Балканах | PC | | Original | | | |
| Special Secret Data Disc | PC | | PSP Game Bundle | | | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Special Forces | PS2 | 1.00 | Original | | SLES-54591 | |
| Special Forces | PC | 1.00 | Hit Squad: Regenerator | | REGEN020 | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
| Special Disc with SegaSaturn Internet 2 SPECIAL DISC with SEGASATURN インターネット2 | SS | 1.020 | Hibaihin | | T-31303G | |
| Special & Delicious! Original CD-ROM | FMT | | Bundled with Book | | TAIYOU-001 | |
| Speccy Classix '98 Speccy Classix 1998 | PC | | | | | |
| Speccy Classix | PC | | Rerelease | | | |
| Spec Ops: Rangers Lead the Way | PC | 1.0 | Original | | CD-RC008 | |
| Spec Ops: Rangers Lead the Way | PC | | Demo | | CD-RC008 | |
| Spec Ops: Ranger Team Bravo | PC | | Original | | CD-RC010 | |
| Spec Ops: Ranger Assault | PC | | Covermount | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | 2.5 | Red Fly | | | |
| Spec Ops: Ranger Assault | PC | | Original | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Extreme | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops II: Operation Bravo | PC | | Lock 'N' Load | | | |
| Spec Ops II: Omega Squad | DC | 1.008 | Original | | T-41704N | |
| Spec Ops II: Omega Squad | DC | 1.002 | Original | | T-45004D-50 | |
| Spec Ops II: Green Berets | PC | 1.00.000 | Original | | CD-RG-003 | |
| Spearhead | PC | | Covermount | | | |
| Spearhead סימולטור טנקים | PC | 1.0.0.1 | Original | | | |
| Spearhead | PC | | Original | | | |
| Spearhead | PC | | Pocket Price | | | |
| Spearhead | PC | | Original | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-1216N | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-36816D-50 | |
| Spaß am Turnierreiten Equestriad 2001 | PC | | Original | | | |
| Spartan XX スパルタン イグゼクス | PC | | Original | | | |
| Spartan | PC | | Sold Out Software | | | |
| Sparrow Garden: Namco Mahjong ナムコマージャン スパローガーデン | PSX | | Original | | SLPS 00074 | |
| Sparkling Feather スパークリング・フェザー | PC-FX | | Original | | FXNHE739 | |
| Spacetanks | PC | 1.0 | Pepper Games | | | |
| Spaceship Warlock | PC | 1.1.3 | Original | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| SpaceHaste 2 SpaceHaste | PC | 1.32 | TopWare Just 4Fun | | | |
| SpaceHaste 2 SpaceHaste: The Next Levels | PC | 2.001 | Covermount | | | |
| SpaceHaste 2 | PC | | Original | | | |
| SpaceHaste BGamer 070 (Disc 2) | PC | | Covermount | | | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Space-Dude: Der Retter des Universums | PC | | Original | | | |
| Space War Attack | PS2 | 1.01 | Original | | SLES-53915 | |
| Space Tripper | PC | | Original | | APWCDR1014 | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Space Station Manager Космоград | PC | 1.2.1 Rus | Original | | | |
| Space Sirens | PC | | Original | | SKU: UN017 | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | PC | Rev A | Bundle Version OEM | | RVL 13-004-073 | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Shuttle スペースシャトル | PHOTO-CD | 1.1 | Original | | C02H | |
| Space Safari | CDI | 01.08 | Original | | 811 0035 | |
| Space Rider | PSX | | Original | | SLES-04126 | |
| Space Rangers | PC | 1.7.2 | Cinemaware Marquee | | 02-1506-12 | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Space Raiders 스페이스 레이더스 VER.2 | PS2 | 1.00 | Original | | SLKA 15002 | |
| Space Raiders スペースレイダース | PS2 | 1.01 | Original | | SLPM 62275 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest I: Roger Wilco in the Sarien Encounter | PC | | Kixx XL | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | | | | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | Original | | S4330520Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | MAC | | Original | | S4330250Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | 1.0 | Original | | S4330220Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | SierraOriginals | | S6460220Z12ZZ | |
| Space Ofera Agga Ruter: Kyoufu no Uchuu Majo Space Ofera アッガ・ルター 恐怖の宇宙魔女 | PC | | Original | | | |
| Space Museum スペース・ミュージアム | FMT | | Original | | | |
| Space Marisar スペースマリサー | PC | 1.00 | Original | | | |
| Space Marines: Der Stählerne Kaiser | PC | | All You Can Play: Adventure & Fantasy | | | |
| Space Marines (Disc 2) | PC | | Classic Line | | | |
| Space Marines (Disc 1) | PC | | Classic Line | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam スペース・ジャム | SS | 1.000 | Original | | T-8119G | |
| Space Jam スペースジャム | PSX | | Original | | SLPS 00697 | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Invaders: The Original Game スペースインベーダー | PC | | Original | | | |
| Space Invaders: The Original Game Space Invaders '95 | PC | | Original | | | |
| Space Invaders X | PC | 1.0.0 | Sourcenext Selection | | | |
| Space Invaders X スペース・インベーダーX | PSX | | Original | | SLPM 86419 | |
| Space Invaders Anniversary 스페이스 인베이더 애니버서리 | PS2 | 1.01 | Original | | SLKA 15025 | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 EUROPEAN | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Space Invaders | PSX | | Review | | | |
| Space Invaders | PC | 1.1 | Xplosiv | | XP-1867 EUROPEAN | |
| Space Invaders | PC | | Original | | 1000916.101.UK | |
| Space Invada!! Type Shinai to Tama ga Denai. SPACE INVA打!! / SPACE INVADERS!! タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Space in Motion: Future Trade | PC | 1.01 | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H | |
| Space Hulk: Vengeance of the Blood Angels | PC | | Original | | E348EDED | |
| Space Hulk | PC | | Original | | E2105CCD | |
| Space Hack | PC | 1.02 | Original | | | |
| Space Empires V Космическая Империя V | PC | 1.66 | Original | | | |
| Space Empires V | PC | 1.30 | Covermount | | | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Space Dynagon Kai スペース大納言(改 | PC | | Original | | MSCD-0026 | |
| Space Dudes | PC | | Original | | | |
| Space Dogs: Adventure to the Moon Белка и Стрелка. Лунные приключения | PC | 1.0.0 | Original | | | |
| Space Debris | PSX | | Original | | SCES-02433 | |
| Space Debris | PSX | | Review | | SCES-02431 | |
| Space Debris | PSX | | Original | | SCES-02431 | |
| Space Debris | PSX | | Original | | SCES-02430 | |
| Space Debris | PSX | | Original | | SCES-02290 | |
| Space Crusade | PC | | | | | |
| Space Colony | PC | | Original | | | |
| Space Colony (Disc 2) (Jugar) | PC | | Original | | | |
| Space Colony (Disc 1) (Instalación) | PC | | Original | | | |
| Space Colony (Install) | PC | | Green Pepper | | | |
| Space Colony (Play) | PC | | Green Pepper | | | |
| Space Colony | PC | | Original | | | |
| Space Clash: The Last Frontier | PC | | Sold Out Software | | | |
| Space Clash | PC | | Original | | M-25324-1999 | |
| Space Clash Space Clash: Das letzte Imperium | PC | | Original | | | |
| Space Channel 5 Theme Music: Mexican Flyer スペース・チャンネル5 | DC | 1.080 | Not for Sale | | | |
| Space Channel 5 Part 2 スペース・チャンネル5 パート2 | DC | 2.000 | Original | | HDR-0190 | |
| Space Channel 5 スペース・チャンネル5 | DC | 0.203 | Taikenban | | 610-7368 | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| Space Bucks: Spedition Galactica | PC | | Game-Pack 3 | | 80222 | |
| Space Bucks | PC | | Original | | | |
| Space Bucks | PC | | Original | | S4710520Z12ZZ | |
| Space Blaster Swarm | PC | | Original | | | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015-50 | |
| Space Adventure Cobra: The Shooting コブラ・ザ・シューティング | PSX | | Original | | SLPS 00312 | |
| Space Ace CD-ROM (PC and Compatibles) Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | 2.0 | | | SANSARL-01 | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | MCD | | Demo | | | |
| Space Ace | PC | 2.1 | All You Can Play: Adventure & Fantasy | | | |
| Space Ace | 3DO | | Bundled with Magazine (Demo) | | | |
| Soviet Strike | PSX | Rev 1 | Greatest Hits | | SLUS-00061 | |
| Soviet Strike ソビエト・ストライク | SS | 1.000 | Original | | T-10621G | |
| Soviet Strike ソビエトストライク | PSX | | Original | | SLPS 00735 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-18 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-50 | |
| Souzou Sozai: Umi Vol. 1 創造素材 海 Vol.1 | PHOTO-CD | | Original | | SEVI-1049 | |
| Souzou Sozai: Europe no Mado Vol. 2 創造素材 ヨーロッパの窓 Vol.2 | PHOTO-CD | | Original | | ERV2 | |
| SouthPeak Interactive E3 2000 Electronic Press Kit | PC | | Press Kit | | | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art": Special CD-ROM サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" SPECIAL CD-ROM | PC | | Original | | ORRS-1 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 3) (Theater) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86410 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 2) (Library) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86409 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 1) (Museum) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86408 | |
| South Park: Chef's Luv Shack | DC | 1.000 | Original | | T-8105D-50 | |
| South Park: Chef's Luv Shack | PSX | | Demo | | SLED-02576 | |
| South Park: Chef's Luv Shack | PC | | Original | | CD194190.00-EUR | |
| South Park Rally | DC | 1.001 | Original | | T-8116N | |
| South Park | PC | | Original | | | |
| Souten no Shiroki Kami no Kura: Great Peak 蒼天の白き神の座 -GREAT PEAK- | PSX | | Original | | SCPS 10058 | |
| Soushun: Tsutaetai Koto 想瞬 ーつたえたいことー | PC | | Original | | | |
| Sousei Seiki Devadasy: Repeator Amara 創世聖紀デヴァダシー REPEATOR AMARA | PC | | PC Game Best Series | | | |
| sourirE | PC | 1.00 | Original | | | |
| Soundtrap | CDI | 1.06 | Original | | 811 0032 | |
| Soundtrack1: The Definitive Xbox Compilation (Disc 2) | PC | | Original | | 314 584 098 2 | |
| Sounds Best on Sound Blaster Every Game Sounds Best on Sound Blaster: 24-bit Advanced HD | PC | | | | | |
| Sound Qube サウンド・キューブ | SS | 1.001 | Original | | T-4318G | |
| Sound Qube サウンド・キューブ | PSX | | Original | | SLPS 01309 | |
| Sound Qube サウンド・キューブ | PSX | | Best of the Best | | SLPS 02716 | |
| Sound Novel Tkool 2 サウンド・ノベル・ツクール2 | SS | 1.003 | Original | | T-2108G | |
| Sound Novel Machi (Disc 2) (10.13-10.15 Incl.) サウンドノベル 街 | SS | 1.001 | Original | | T-34001G | |
| Sound Eye Julian (Disc 4) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 3) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 2) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| Sound Eye Julian (Disc 1) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |
| SoulTrap Qualche gioco vi ha divertito. Pochi vi hanno appassionato. Solamente SoulTrap vi catturerà l'anima. | PC | | Microforum | | | |
| Soultrap | PC | | Original | | | |
| SoulStar | MCD | | Original | | T-115035 | |
| SoulStar | MCD | | Original | | T-115035-50 | |
| Soulcalibur ソウルキャリバー | DC | 0.600 | Book Bundle | | 610-7175 | |
| Soulbringer (Disc 1) | PC | | Original | | CD-C95-1077-0 | |
| Soulbringer (Disc 2) 引魂者 | PC | | Original | | | |
| Soulbringer (Disc 1) 引魂者 | PC | | Original | | | |
| Soulbringer | PC | | uWish Games | | UWB093 | |
| Soulbringer (Disc 2) | PC | 1.0.0.1 | Original | | | |
| Soulbringer (Disc 1) | PC | 1.0.0.1 | Original | | | |
| The Soul 소울 | PC | | Original | | | |
| Soul Slayers (Disc 2) 聖靈騎士 | PC | 1.3 | Original | | | |
| Soul Slayers (Disc 1) 聖靈騎士 | PC | 1.3 | Original | | | |
| Soul Ride | PC | | Linux (LGP) | | | |
| Soul Hunt (Disc 3) | PC | | Original | | | |
| Soul Hunt (Disc 2) | PC | | Original | | | |
| Soul Hunt (Disc 1) | PC | | Original | | | |
| Soul Fighter | DC | 1.000 | Original | | T-41401N | |
| Soul Eater: Battle Resonance: Tamashii Kyoumei Disc ソウルイーター バトルレゾナンス 魂共鳴ディスク | PC | | Yoyaku Tokuten | | | |
| Soukyuu Gurentai: Oubu Shutsugeki 蒼穹紅蓮隊 黄武出撃 | PSX | | Original | | SLPS 01172 | |
| Soukyuu Gurentai 蒼穹紅蓮隊 | SS | 1.003 | Original | | T-10616G | |
| Soukuu no Tsubasa: Gotha World (Disc 2) 蒼空の翼 -GOTHA WORLD- | SS | 1.000 | Original | | T-2205G | |
| Soukuu no Tsubasa: Gotha World (Disc 2) 蒼空の翼 -GOTHA WORLD- | PSX | | Original | | SLPS 01042 | |
| Soukuu no Tsubasa: Gotha World (Disc 1) 蒼空の翼 -GOTHA WORLD- | SS | 1.000 | Original | | T-2205G | |
| Soukuu no Tsubasa: Gotha World (Disc 1) 蒼空の翼 -GOTHA WORLD- | PSX | | Original | | SLPS 01041 | |
| Soukuu no Tsubasa: Gotha World 蒼空の翼 -GO THAWORLD- | SS | 1.000 | Sample CD | | 610-6710 | |
| Soukouhime Baldrfist 装甲姫バルフィス | PC | | Baldr Masterpiece Chronicle | | | |
| Soukou no Kihei: Space Griffon 蒼鋼の騎兵 -SPACE GRIFFON- | DC | 1.001 | Original | | T-39601M | |
| Soukou Kihei Votoms: Woodo Kummen 装甲騎兵ボトムズ ~ウド・クメン編~ | PSX | | Original | | SLPS 01331 | |
| Soukou Kihei Votoms: Woodo Kummen 装甲騎兵ボトムズ ~ウド・クメン編~ | PSX | | Limited Edition | | SLPS 01330 | |
| Soukou Kihei Votoms: Lightning Slash 装甲騎兵ボトムズ ライトニング・スラッシュ | PSX | | Limited Edition | | SLPS 01960 | |
| Soukou Kihei Votoms: Lightning Slash 装甲騎兵ボトムズ ライトニングスラッシュ | PSX | | Taikenban | | SLPM 80360 | |
| Soukou Kihei Votoms: Lightning Slash 装甲騎兵ボトムズ ライトニング・スラッシュ | PSX | | Original | | SLPS 01961 | |
| Soukou Kihei Votoms: Koutetsu no Gunzei 装甲騎兵ボトムズ 鋼鉄の軍勢 | PSX | | Original | | SLPS 02315 | |
| Soukou Kihei Votoms Gaiden: Ao no Kishi Berserga Monogatari 装甲騎兵ボトムズ外伝 ~青の騎士 ベルゼルガ物語~ | PSX | | Limited Edition | | SLPS 00981 | |
| Soukoku no Kusabi: Hiiro no Kakera 3 Portable: Genteiban Tokuten Desktop Accessory-shuu 蒼黒の楔 緋色の欠片3 ポータブル 限定版特典 デスクトップアクセサリー集 | PC | | PSP Game Bundle | | | |
| Soukoban: Nanmon Shinan 倉庫番 難問指南 | PSX | | Original | | SLPS 02010 | |
| Soukoban Special 102 倉庫番スペシャル102 | PC | | Original | | | |
| Soukoban Basic 2 倉庫番ベーシック2 | PSX | | Original | | SLPS 01519 | |
| Soukoban Basic 倉庫番ベーシック | PC | | Original | | SKB-007-1 | |
| Soukoban Basic 倉庫番ベーシック | PSX | | Original | | SLPS 00924 | |
| Soukoban 倉庫番 | PC | | Original | | SCB-055-1 | |
| Soukoban 倉庫番 | PC | | Konbini Sen'you | | CSKB-46-1 | |
| Souko Mania 2 倉庫マニア2 | PC | | Original | | MSDJ-02012 | |
| Sougaku Toshi Osaka (Disc 2) (Object) 騒楽都市 OSAKA | PSX | | Original | | SLPS 01723 | |
| Sougaku Toshi Osaka (Disc 1) (Method) 騒楽都市 OSAKA | PSX | | Original | | SLPS 01722 | |
| Sotsugyousei 卒業生 | PC | | Original | | JAW-17 | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Demo-ban | | FZ-JJ9DSS-4K | |
| Sotsugyou: Graduation: Final 卒業 -FINAL- | 3DO | | Original | | FZ-SJ1661 | |
| Sotsugyou: Graduation S 卒業S | SS | 1.001 | Original | | T-20103G | |
| Sotsugyou: Graduation '93 卒業’93 | FMT | | Original | | JH-002 | |
| Sotsugyou: Graduation 卒業 ~グラデュエーション~ | PCE | | Original | | NAPR-1036 | |
| Sotsugyou R: Graduation Real 卒業R -Graduation Real- | PC-FX | | Original | | FXNAV602 | |
| Sotsugyou R: Graduation Real 卒業R Graduation Real | PSX | | Shokaiban | | SLPS 00261 | |
| Sotsugyou M: Seito Kaichou no Karei naru Inbou (Disc 2) 卒業M ~生徒会長の華麗なる陰謀~ | PSX | | Original | | SLPS 01445 | |
| Sotsugyou M: Seito Kaichou no Karei naru Inbou (Disc 1) 卒業M ~生徒会長の華麗なる陰謀~ | PSX | | Original | | SLPS 01444 | |
| Sotsugyou III: Wedding Bell 卒業Ⅲ -Wedding Bell- | SS | 1.003 | Shokai Genteiban | | T-10506G | |
| Sotsugyou II: Neo Generation 卒業II Neo generation | PC | | Original | | | |
| Sotsugyou Genga-shuu 卒業原画集 | PHOTO-CD | | Original | | CRMP-1001 | |
| Sotsugyou Album 卒業アルバム | SS | 1.002 | Original | | T-10504G | |
| Sostojanie Vojny 2 (Disc 2) Состояние Войны 2 | PC | | Original | | | |
| Sostojanie Vojny 2 (Disc 1) (Igrovoj) Состояние Войны 2 | PC | | Original | | | |
| Sorting Adventures: Interactive Activities | PC | | Original | | AAP899, PP463 | |
| Sortilèges: Rage of Mages II Rage of Mages II: Necromancer | PC | | Original | | | |
| Sorry! | PC | | Original | | 99040 | |
| Sorry / Boggle / Yahtzee: Triple Pack of Fun | PC | | Original | | Part # 26023CD | |
| Sorority House: An Interactive Game of Hide and Peek | PC | 1.0 | Original | | | |
| Soreike! Anpanman: Tanoshii Eigo Asobi それいけ! アンパンマン ~たのしいえいごあそび~ | FMT | | Original | | FMB-3010 | |
| Soreike no Kokology: Kokoro ga Oshieru Koi, Kekkon, Jinsei それいけ×ココロジー 心が教える 恋・結婚・人生 | PSX | | Original | | SLPS 00484 | |
| Soreike Flyfishing: Let's Go Flyfishing それ行けフライフィッシング | PSX | | Original | | SLPS 01827 | |
| Sorcerous Stabber Orphen 魔術士オーフェン | PS2 | 1.00 | Taikenban | | SLPM 60113 | |
| Sorcerian Original ソーサリアンオリジナル | PC | 1.00 | Original | | NF03026 | |
| Sorcerian Original ソーサリアンオリジナル | PC | | Demo | | | |
| Sorcerian Forever 魔域傳說 永恆之書 | PC | | Game Box Taiwan Release | | | |
| Sorcerian Forever ソーサリアン・フォーエバー | PC | | Ultra 2000/Ultra Series | | MKW-274 | |
| Sorcerian Forever ソーサリアン・フォーエバー | PC | | Premium-ban | | NF03006 | |
| Sorcerer's Maze | PSX | | Original | | SLES-04086 | |
| Soratobu Akai Wine Taru: A Diary of Little Aviator 空飛ぶ赤いワイン樽 ~A Diary of Little Aviator~ | PC | 1.0 | Original | | ORDD-0007 | |
| Sorades: Die Befreiung | PC | 1.3 | Original | | | |
| Sora no Fudousan 空の浮動産 | PC | | Original | | ANOS-02 | |
| Sora no Fudousan 空の浮動産 | PC | | for X68000 & Windows Doukonban | | ANOS-05 | |
| Sora ソラ | PC | 1.0 | Original | | ORDD-0009 | |
| Sophie's World | PC | UK Version 1.0 | Original | | | |
| Sophie's World ソフィーの世界 | PC | 2.0 | Original | | | |
| Sonya | PC | | Original | | | |
| Sony PlayStation 2: SCEA Santa Monica Studios: 2004 Press Information: Press Print | PC | | Press Kit | | | |
| Sony Music Entertainment: PlayStation Title Digest Sony Music Entertainment: PlayStation Tittle Digest | PSX | | Hibaihin | | SLPM 80148 | |
| Sony Image Converter 2: Ver.2.1 | PC | 2.1.00.14241 | Original | | MSSW-IC2 | |
| Sony E3 2004: Press Information | PC | | Press Kit | | | |
| Sony Double Impact Games | PSX | | | | SCED-02204 | |
| Sony Computer Entertainment Inc. Monthly Software Information: 6-gatsu Hatsubai Yotei Title Sony Computer Entertainment Inc. Monthly Software Information 6月発売予定タイトル | PSX | | Taikenban | | PCPX 96154 | |
| Sony Computer Entertainment Hyper Fan Book ソニーコンピューターエンターテイメント ハイパーファンブック | PSX | | Bundled with Book | | SLPM 80355 | |
| Sony Computer Entertainment Europe: ECTS 2000 Information Card | PC | | Original | | | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| SonicFury: Software and Documentation | PC | 2 | | | 8/00 11K39 | |
| Sonic Wings Special ソニック・ウィングス・スペシャル | PSX | | Original | | SLPS 00307 | |
| Sonic the Hedgehog CD | MCD | 1.05 | Beta | | | |
| Sonic the Hedgehog CD | MCD | 0.70 | Beta | | | |
| Sonic the Hedgehog CD ソニック・ザ・ヘッジホッグ CD | PC | | Rerelease | | HCJ-0104 | |
| Sonic the Hedgehog CD ソニック・ザ・ヘッジホッグCD | MCD | | Sample | | SG-6021 | |
| Sonic Shuffle | DC | 1.000 | Original | | 51060 | |
| Sonic Shuffle ソニックシャッフル | DC | 1.001 | Original | | HDR-0125 | |
| Sonic Shuffle | DC | 1.000 | Original | | MK-51060-50 | |
| Sonic Riders (Disc 1) | PC | 1.0 | Scholastic | | P/N CDR5047633 | |
| Sonic Riders (Disc 1) | PC | 1.0 | Original | | | |
| Sonic Riders (Assets) | PC | | Press Kit | | | |
| Sonic R | PC | | Original | | 85076 | |
| Sonic R | PC | | Sonic R & Sonic 3D (PC Best Buy) | | 177501A | |
| Sonic R ソニックR | SS | 1.002 | Original | | GS-9170 | |
| Sonic R ソニックR | PC | | Ultra 2000/Ultra Series | | MKW-111 | |