| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Sonic the Hedgehog CD
ソニック・ザ・ヘッジホッグＣＤ | PC | 1.001 | Ultra 2000/Ultra Series |   | MKW-160 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Sonic R | SS | 1.000 | Original, Not for Resale | | 81800, 191306 | |
 | Sonic R | PC | | Expert Software | | 682501.101.US, 682501.101.US 01 | |
| Sonic R
ソニックＲ | SS | 1.002 | Original | | GS-9170 | |
 | Sonic R | PC | | Original | | MK 85076-50 | |
| Sonic Jam | SS | 1.004 | Original | | 81079 | |
| Sonic CD | PC | 1.1 | Expert Software | | 6805 02 | |
| Sonic CD | PC | | Expert Software | | 6805 02 | |
| Sonic CD | PC | | Original, Family Pack | | 500-0014-50, MK 85015-50, MK 85086-50 | |
| Sonic 3D: Flickies' Island | PC | | Original | | MK 85064-50 | |
| Sonic 3D Blast | PC | 1.00 | Original | | 85064 | |
| Solo Crisis
ソロ・クライシス | SS | 1.001 | Taiken Sample-ban | | 610-6802 | |
| Solo Crisis
ソロ・クライシス | SS | 1.000 | Original | | T-23501G | |
| Soldier of Fortune | PC | 1.06 | Gold Edition |  | 30173.101.US | |
| Soldier of Fortune | PC | 1.03 | Special Tactical Edition | | 1001348.101.US | |
| Soldier of Fortune | PC | 1.03 | Original | | 1000910.101.US | |
| Sol Divide
ソル・ディバイド | SS | 1.000 | Original | | T-14423G | |
| The Software Toolworks' Star Wars Chess | MCD | | Original | | T-87035 | |
| Snatcher
スナッチャー | SS | 1.000 | Original | | T-9508G | |
| Slayers Royal 2
スレイヤーズろいやる２ | SS | 1.005 | Original | | T-27907G | |
| Slam Tilt | PC | | Original | | | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | MCD | | Original | | 063636, T162035 | |
| Slam City with Scottie Pippen (Disc 2) (Juice) | MCD | | Original | | 063636, T162035 | |
| Slam City with Scottie Pippen (Disc 1) (Fingers) | MCD | | Original | | 063636, T162035 | |
| Skeleton Krew | CD32 | | Original | | | |
| Silverload | PC | | | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.01 | Rerelease | | | |
| Silent Thunder: A-10 Tank Killer II | PC | | Rerelease | | S691140 | |
 | Die Siedler: Platin Edition I · II · III · IV (Disc 3) | PC | | Platin Edition |  | | |
| Die Siedler: Platin Edition I · II · III · IV (Disc 1) | PC | | Platin Edition | | | |
| Die Siedler III (Disc 2) | PC | | Purple Hills | | | |
| Die Siedler III (Disc 1) | PC | | Purple Hills | | | |
| Die Siedler II: Gold Edition | PC | 1.51 | Original | | | |
| Sid Meier's Civilization II
シヴィライゼーションⅡ | PC | 2.11J | Original, Value Pack | | | |
| Sid Meier's Civilization II | PC | | Original | | MP391260DO1R | |
| Sid Meier's Civilization II | PC | 1.02 | Original, Collector's Edition | | MPX91260DO1R | |
| Shutsudou! Miniskirt Police
出動！ミニスカ・ポリス | SS | 1.001 | Original, Shokai Gentei Double Tokuten | | T-30810G, T-30812G | |
| Shrak
Shrak for Quake | PC | 1.0 | Original | | | |
 | Shouhuzhe Zhi Jian (Disc 2)
守护者之剑 | PC | | Original |  | | |
| Shouhuzhe Zhi Jian (Disc 1)
守护者之剑 | PC | | Original | | | |
| Shiroki Majo: Mou Hitotsu no Eiyuu Densetsu (Disc 2)
白き魔女 ～もうひとつの英雄伝説～ | SS | 1.001 | Original | | T-14322G | |
| Shiroki Majo: Mou Hitotsu no Eiyuu Densetsu (Disc 1)
白き魔女 ～もうひとつの英雄伝説～ | SS | 1.001 | Original | | T-14322G | |
| Shinrei Jusatsushi Taroumaru
心霊呪殺師 太郎丸 | SS | 1.004 | Original | | T-4804G | |
| Shinpi no Sekai El-Hazard: El-Hazard: The Magnificent World for Sega Saturn
神秘の世界エルハザード ＦＯＲ ＳＥＧＡ ＳＡＴＵＲＮ | SS | 1.002 | Shokai Tokuten | | T-22202G | |
| Shining the Holy Ark | SS | 1.003 | Original | | 81306 | |
| Shining the Holy Ark
シャイニング・ザ・ホーリィアーク | SS | 1.005 | Original | | T-33101G | |
| Shining the Holy Ark
シャイニング・ザ・ホーリィアーク | SS | 1.005 | Original | | T-33101G | |
| Shin Nihon Pro Wrestling: '94 Battlefield in Tokyo Dome
新日本プロレスリング ’９４バトルフィールド ｉｎ 闘強導夢 | PCE | | Original | | FCCD4001 | |
| Shienryuu
紫炎龍 | SS | 1.000 | Original | | T-29102G | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective | MCD | | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | T-4501 | |
| Shattered Steel | PC | 1.08 | | | CD-ICD-201-M9 | |
| Shanghai: Banri no Choujou: The Great Wall
上海 ～万里の長城～ | SS | 1.005 | Satakore | | T-1527G | |
| Shamrock Spring '97
Shamrock Spring '97 Demo Disk | PC | | | | | |
| Shadows of the Tusk
シャドウズ・オブ・ザ・タスク | SS | 1.001 | Original | | T-14319G | |
 | ShadowCaster | PC | | Original | | | |
| Shadow Warrior
Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow Fighter | CD32 | | Original | | | |
| Sexy Parodius
セクシー・パロディウス | SS | 1.040 | Original | | T-9514G | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Settlers II, The: Veni, Vidi, Vici | PC | 1.02 | Original | | | |
| Sentimental Graffiti: First Window
センチメンタル・グラフティ ～ファースト・ウィンドウ～ | SS | 1.002 | Original | | T-20111G | |
| Sentimental Graffiti (Disc 2) (Second Window)
センチメンタル・グラフティ | SS | 1.000 | Original | | T-20106G | |
| Sentimental Graffiti (Disc 2) (Second Window)
センチメンタル・グラフティ | SS | 1.000 | Original | | T-20106G | |
| Sentimental Graffiti (Disc 1) (Game Disc)
センチメンタル・グラフティ | SS | 1.003 | Original | | T-20106G | |
| Sentimental Graffiti (Disc 1) (Game Disc)
センチメンタル・グラフティ | SS | 1.003 | Original | | T-20106G | |
| Sentimental Graffiti (Disc 1) (Game Disc)
センチメンタル・グラフティ | SS | 1.003 | Original | | T-20106G | |
| Sensible World of Soccer '96/'97 | PC | 2.0 | Original |  | | |
| Sensible Soccer: European Champions | CD32 | | Original | | SSI 1 | |
| Sensible Soccer | MCD | | Bundled with Magazine (Playable Demo - Mega Power Disc 5, Demo) | | | |
| Senkutsu Katsuryu Taisen: Chaos Seed (Disc 2) (Omake Disc)
仙窟活龍大戦 カオス・シード | SS | 1.003 | Original | | T-30902G | |
| Senkutsu Katsuryu Taisen: Chaos Seed (Disc 1) (Game Disc)
仙窟活龍大戦 カオス・シード | SS | 2.000 | Satakore | | T-30904G | |
| Senkutsu Katsuryu Taisen: Chaos Seed (Disc 1) (Game Disc)
仙窟活龍大戦 カオス・シード | SS | 1.005 | Original | | T-30902G | |
| Sengoku Blade: Sengoku Ace Episode II (Disc 2) (Sengoku Kawaraban: Digital Edition)
戦国ブレード | SS | 1.002 | Original | | T-14410G | |
| Sengoku Blade: Sengoku Ace Episode II (Disc 1)
戦国ブレード | SS | 1.002 | Original | | T-14410G | |
| Segakore Sega Bible Mogitate SegaSaturn Soukangou
セガコレセガバイブルモギタテセガサターン。 創刊号 １９９７．１１ | SS | 1.000 | Hibaihin | | 610-6805-01 | |
| Sega Worldwide Soccer PC
セガワールドワイドサッカーＰＣ | PC | 1.09J | PCHome | | 506-9781 | |
| Sega Worldwide Soccer PC | PC | | Original | | MK 85056-50 | |
| Sega Worldwide Soccer '98
セガ・ワールドワイド・サッカー’９８ | SS | 1.002 | Original | | GS-9187 | |
| Sega Touring Car Championship | SS | 1.001 | Original, Sample | | 81216 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | MK 85067-50 | |
| Sega Rally Championship PC | PC | 2.11 | Fair Game, Grabit | | FG-1282, GDL016 | |
| Sega Rally Championship PC | PC | 1.0 | Original | | MK 85048-50 | |
| Sega Puzzle Pack | PC | | Original | | 673-01815 | |
| Sega International Victory Goal
セガ インターナショナル ビクトリー・ゴール | SS | 1.000 | Original | | GS-9044 | |
| Sega Ages: Space Harrier
セガエイジス スペース・ハリアー | SS | 1.002 | Original, Gentei Special Set | | GS-9108, GS-9111 | |
| Sega Ages: Phantasy Star Collection
セガ・エイジス ファンタシー・スター・コレクション | SS | 1.003 | Original | | GS-9186 | |
| Sega Ages: I Love Mickey Mouse: Fushigi no Oshiro Daibouken & I Love Donald Duck: Georgia Ou no Hihou
セガエイジス アイ・ラブ・ミッキー・マウス ～ふしぎのお城 大冒険～ ／ アイ・ラブ・ドナルド・ダック ～グルジア王の秘宝～ | SS | 1.000 | Original | | GS-9179 | |
| Secrets of Tatjana | CDI | | Original, Demonstration Disc | | 810 0046 | |
 | Secret Service CD 56 (Strona A) | PC | | | | | |
| Secret Service CD 55 (Strona B) | PC | | | | | |
| Secret Service CD 55 (Strona A) | PC | | | | | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| Search & Rescue 2 | PC | | Original |  | | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer | PC | | Screamer Injection | | | |
| Scorcher | PC | | Original | | 04-11264CD | |
