| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Sesame Street: Elmo's Number Journey | PSX | | Original, Twin Pack |  | SLUS-00622 … | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Setup Utility for DTL-H1500 (Version 1.1) | PSX | | Original |  | | |
| Sewer Shark | MCD | Rev 1 | Original | | T-6201 | |
| Shadow Madness | PSX | | Demo | | SLUS-90031 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SLUS-00468 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SLUS-00718 | |
| Shadow Man | PSX | | Original | | SLUS-00895 | |
| Shadow Master | PSX | | Original | | SLUS-00545 | |
| Shadow of Rome | PS2 | 1.00 | Demo | | SLUS 29139 | |
| Shadow of the Colossus | PS2 | 1.00 | Demo | | SCUS 97505 | |
| Shadow the Hedgehog | PS2 | 1.02 | Original, Greatest Hits |     | SLUS 21261 … | |
| Shadow Tower | PSX | | Original | | SLUS-00863 | |
| Shanghai: Triple-Threat | 3DO | | 3DO Action Pak | | | |
| Shanghai: True Valor | PSX | | Original | | SLUS-00795 | |
| SharkPort: Code and Save Transfer Kit | PC | 1.04 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PC | 1.10 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.2 | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 2.21 | Unlicensed | | | |
| Sheep | PSX | | Original | | SLUS-01298 | |
| Shelley Duvall's It's a Bird's Life | 3DO | | Original | | | |
| Shellshock | PSX | | Original | | SLUS-00031 | |
| Sherlock Holmes: Consulting Detective | MCD | | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | T-4501 | |
| Shin Megami Tensei: Persona 3 | PS2 | 1.00 | Trade Demo | | SLUS-28067 | |
| Shin Megami Tensei: Persona 4 | PS2 | 1.00 | Trade Demo | | SLUS-28069 | |
 | Shin Samurai Spirits: Haoumaru Jigokuhen ~ Samurai Shodown II
真サムライ・スピリッツ ～覇王丸地獄変～ | NGCD | | Original | | NGCD-063, NGCD-063E | |
| Shin Sangoku Musou
真・三國無双 | PS2 | 1.20 | Original, PlayStation 2 the Best, Koei 2002 Spring Pack, Koei Teiban Series | | SLPM 62005 … | |
| Shin Sangoku Musou 2
真・三國無双２ | PS2 | 1.30 | Original, Koei 2002 Spring Pack, Koei Teiban Series, Mega Hits! | | SLPM 65053 … | |
| Shin Sangoku Musou 2: Moushouden
真・三國無双２ 猛将伝 | PS2 | 1.05 | Original, Koei Teiban Series | | SLPM 65170 … | |
 | Shin Sangoku Musou 3
真・三國無双３ | PS2 | 1.03 | Original, PlayStation 2 the Best, Shin Sangoku Musou 3 Treasure Box, Shin Sangoku Musou 3 Super Premium Box, Koei Teiban Series | | SLAJ 25011 … | |
| Shin Sangoku Musou 3: Moushouden
真・三國無双３ 猛将伝 | PS2 | 1.01 | Original, PlayStation 2 the Best, Shin Sangoku Musou 3: Empires & Moushouden Premium Box, Shin Sangoku Musou 3 Super Premium Box, Koei Mega Pack, Koei Teiban Series | | SLAJ 25023 … | |
| Shin Sedai Robot Senki: Brave Saga
新世代ロボット戦記 ＢＲＡＶＥ ＳＡＧＡ | PSX | | Brave Charge Box | | SLPS 01755 | |
| Shin Seiki Evangelion
新世紀エヴァンゲリオン | SS | 1.005 | Original, Shin Package | | GS-9051, GS-9141 | |
| Shipwreckers! | PSX | | Original | | SLUS-00558 | |
| Shipwreckers! | PSX | | Demo | | SLUS-90013 | |
| Shock Wave
ショックウェーブ | PSX | | Original | | SLPS 00419 | |
| Shock Wave | 3DO | RE1 | Original, Demo Disc (3DO Demo Disc Program) | | 7222 | |
| Shock Wave | 3DO | RE2 | Original, Not for Resale | | | |
 | Shock Wave: Operation JumpGate | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Shockwave Assault (Disc 1) (Shockwave: Invasion Earth) | PSX | | Original | | SLUS-00028 | |
| Shockwave Assault (Disc 2) (Shockwave: Operation Jumpgate) | PSX | | Original | | SLUS-00137 | |
| Shrek Treasure Hunt | PSX | | Original | | SLUS-01463 | |
| Sid Meier's Civilization IV: Beyond the Sword (Disc 1) | PC | 3.0.3.1 (77541) | Rerelease | | 31173-1.1 | |
| Sid Meier's Civilization IV: Beyond the Sword (Disc 2) | PC | 3.0.3.1 (77541) | Rerelease | | 31173-1.2 | |
| Sidewinder 2: Let's Dance in the Sky
サイドワインダー２ | PSX | | Original, PlayStation the Best | | SLPS 00954 … | |
| Silent Bomber | PSX | | Original | | SLUS-00902 | |
 | Silent Hill | PSX | | Demo | | SLED-02186 | |
 | Silent Hill | PSX | | Demo | | SLED-01735 | |
| Silent Hill
サイレントヒル | PSX | | Trial Version | | SLPM 80363 | |
| Silent Hill | PSX | | Original, Greatest Hits | | SLUS-00707 … | |
| Silent Hill | PSX | | Trade Demo | | SLUS-80707 | |
| Silent Hill | PSX | | Demo | | SLUS-90050 | |
| Silhouette Mirage | PSX | | Original | | SLUS-00728 … | |
| Silverload | PSX | | Original | | SLUS-00050 | |
| SimCity 2000 | PSX | | Original, Greatest Hits | | SLUS-00113 … | |
| Simple 1500 Jitsuyou Series Vol. 02: Katei no Fuusui
ＳＩＭＰＬＥ１５００実用シリーズ Ｖｏｌ．０２ 家庭の風水 | PSX | | Original | | SLPS 02843 | |
| Simple 2000 Series Vol. 18: The Party Sugoroku
ＳＩＭＰＬＥ２０００シリーズ Ｖｏｌ．１８ ＴＨＥ パーティーすごろく | PS2 | 1.02 | Original | | SLPM 62272 | |
| Simple 2000 Series Vol. 39: The Boku no Machi-zukuri: Matching Maker++
ＳＩＭＰＬＥ２０００シリーズ Ｖｏｌ．３９ ＴＨＥ ぼくの街づくり ～街ｉｎｇメーカー＋ ＋ ～ | PS2 | 1.01 | Original | | SLPM 62398 | |
| The Simpsons Wrestling | PSX | | Original | | SLUS-01227 | |
| The Sims 2 | PS2 | 1.00 | Original, Greatest Hits | | SLUS 21265 … | |
| The Sims 2 | PS2 | 1.00 | Demo | | SLUS 29173 | |
 | The Sims 2: Castaway | PS2 | 1.00 | Original | | SLUS 21664 | |
| The Sims | PC | | Bundle Version Gateway OEM | | 1500827 | |
| SimTheme Park
Sim Theme Park | PSX | | Original | | SLUS-01069 | |
| SingStar '90s | PS2 | 1.00 | Original | | SCUS 97626 | |
| Siren | PS2 | 1.00 | Demo | | SCUS 97398 | |
| Skeleton Warriors | PSX | | Original | | SLUS-00209 | |
| Skullmonkeys | PSX | | Original, Promo | | SLES-01090 | |
| Skullmonkeys | PSX | | Original | | SLUS-00601 | |
| Skydiving Extreme | PSX | | Original | | SLUS-01392 | |
| SkyGunner | PS2 | 1.00 | Demo | | SLUS 29020 | |
| Slam 'n Jam '95 | 3DO | | Original | | 60140-C | |
| Slam 'n Jam '95 | 3DO | | Original | | | |
| Slam 'n Jam '96 featuring Magic & Kareem | PSX | | Original | | SLUS-00022 | |
| Slamscape | PSX | | Original | | SLUS-00080 | |
| Sled Storm | PSX | | Original, Greatest Hits, Collectors' Edition | | SLUS-00955 … | |
| Sled Storm & Medal of Honor Demo CD | PSX | | | | SLUS-90072 | |
| Slim Jim | PSX | | | | SCUS-94472 | |
| Slomanny'j mech Chast' 2: Dy'myashheesya zerkalo (Disc 3)
Сломанный меч Часть 2: Дымящееся зеркало | PC | | Original |  | | |
| Slomanny'j mech Chast' 2: Dy'myashheesya zerkalo (Disc 4)
Сломанный меч Часть 2: Дымящееся зеркало | PC | | Original | | | |
| Slots | PSX | | Original | | SLUS-01555 | |
| Slotter Mania 7: Gekiatsu! Siosai-musume Seizoroi DX + Apache A
スロッターマニア７ 激熱！シオサイ姫勢揃いＤＸ＋アパッチＡ | PSX | | Original | | SLPS 03511 | |
| Slotter Mania 9: Gokunetsu 30 Phi! Haibi & Splash Seven
スロッターマニア９ 極熱３０φ！ハイビ＆スプラッシュセブン | PSX | | Original | | SLPS 03533 | |
| Sly 2: Band of Thieves | PS2 | 1.00 | Demo | | SCUS 97457 | |
| Sly 3: Honor Among Thieves | PS2 | 1.00 | Demo | | SCUS 97527 | |
| Sly Cooper and the Thievius Raccoonus | PS2 | 1.00 | Demo | | SCUS 97210 | |
| Small Soldiers | PSX | | Original | | SLUS-00781 | |
| Smurf Racer! | PSX | | Original | | SLUS-01359 | |
| The Smurfs | PSX | | Original | | SLUS-01008 | |
| SnoCross Championship Racing
Sno-Cross Championship Racing | PSX | | Original | | SLUS-01093 | |
| Snowboarding | PSX | | Original | | SLUS-01287 | |
| Soccer Kantoku Saihai Simulation: Formation Final
サッカー監督采配シミュレーション ＦＯＲＭＡＴＩＯＮ ＦＩＮＡＬ | PS2 | 1.02 | Original | | SLPM 65372 | |
| Soccer Life! We are Challengers to Europe
サッカー選手育成シミュレーション サッカーライフ！ Ｗｅ ａｒｅ ｃｈａｌｌｅｎｇｅｒｓ ｔｏ ＥＵＲＯＰＥ | PS2 | 1.02 | Original | | SLPS 20350 | |
| SOCOM 3: U.S. Navy SEALs | PS2 | 1.00 | Beta | | SCUS 97489 | |
| SOCOM 3: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97475 | |
| SOCOM: U.S. Navy SEALs | PS2 | 1.00 | Demo | | SCUS 97205 | |
| SOCOM: U.S. Navy SEALs: Combined Assault | PS2 | 1.00 | Original, Greatest Hits | | SCUS 97545 | |
| SOCOM: U.S. Navy SEALs: Combined Assault | PS2 | 1.00 | Demo | | SCUS 97560 | |
| Sol Divide | PSX | | Original | | SLUS-01519 | |
