| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Second Sight | PC | | 1C: Kollekciya igrushek |  | |  |
 | Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
 | Secret Files 2: Puritas Cordis | PC | | Original |  | ECD900341D | |
 | Secret Files: Il Mistero di Tunguska | PC | 1.00 | Covermount |  | | |
| Secret Files: Tunguska | PC | 1.03 | Original, Xplosiv |  | ECD008099M 00060722-01, ECD900019D 00060810-01, XP-2221 3026412 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Secret Files: Tunguska | PC | | Original | | ECD900019D 00060907-02 | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit |   | | |
 | The Secret of the Silver Earring
Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
 | Secret Service | PC | 1.0 | Original | | 35635.101.UK, 35635.101.US | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
 | Sega Hard Historia
セガハードヒストリーア | PC | | Book Bundle |  | | |
| Sega PC Collection Vol. 1 | PC | | PC Game Bundle | | 673-04569 | |
| Sega PC Collection Vol. 2 | PC | | PC Game Bundle | | 673-04572 | |
 | Sega Rally | PC | 1.0 | Original | | SEGA-PC056 | |
 | Sega Rally | PC | | eXtra Klasyka XK Hit | | | |
| Sega Rally | PC | 3.2.0.3 | Original, TopSeller |  | | |
| Seikai no Senki
星界の戦旗 | PC | | Original | | | |
| Seikishi Melty Lovers
聖騎士Ｍｅｌｔｙ☆Ｌｏｖｅｒｓ | PC | 1.00 | Original | | AKT-0010 | |
| Seinarukana: The Spirit of Eternity Sword 2
聖なるかな ーＴｈｅ Ｓｐｉｒｉｔ ｏｆ Ｅｔｅｒｎｉｔｙ Ｓｗｏｒｄ ２ー | PC | | Special Package | | | |
| Sekai no Subete: Remind of You
世界ノ全テ －ｒｅｍｉｎｄ ｏｆ ｙｏｕ－ | PC | 1.0.0.0 | Renewal Package Ban | | | |
| Sengoku Hime: Hana: Shinroku Tenka wo Kirisaku Hikari to Kage
戦極姫・華 ~真録・天下を切り裂く光と影~ | PC | | Original | | | |
| Sengoku Hime: Senran no Yo ni Homura Tatsu: Shinsouban
戦極姫 ~戦乱の世に焔立つ~【新装版】 | PC | | Unicorn-a Selection 6 | | | |
| Sengoku Musou 2
戦国無双2 | PC | 1.0 | Original | | KOEI-30130 | |
 | Sengoku Musou 2
戰國無雙２ | PC | 1.0 | Original |  | 08.06.11131 | |
| Sengoku Rance
戦国ランス | PC | 1.00 | Original | | ALS-0061 | |
| Sengoku Rance
戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Senjin Otome: Makina ni Yadorishi Kokoro ga Negau wa...
戦刃乙女 －マキナに宿りし心が願うは…－ | PC | 1.00 | Original | | DEBO-13003 | |
| Separate Hearts
散碎的原色 | PC | | Original | | CV022 | |
| Sequence Palladium 2: Yami no Shousei
シークエンス・パラディウム２ ～闇の笑声～ | PC | | Rerelease | | KGD-04080 | |
| Sequence Palladium Aizouban
シークエンス パラディウム 愛蔵版 | PC | | Original | | KGDP075 | |
| Serdce Vechnosti
Сердце Вечности | PC | 1.0 | Original | | | |
| Serious Sam 3: BFE | PC | | Original | | MTC000692-D | |
| Serious Sam 3: BFE | PC | 1.0 | Original |  | | |
| Serious Sam HD: The First Encounter | PC | | Original | | | |
| Serious Sam HD: The First Encounter
Крутой Сэм HD: Первая кровь | PC | | Original | | | |
| Serious Sam HD: The Second Encounter
Serious Sam HD: Второе Пришествие | PC | | Original | | | |
| Serious Sam II | PC | | Sold Out Software | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | | | Y03G0017 | |
| Serious Sam II | PC | | Original | | | |
 | Serious Sam II | PC | 2.068.00 : 62787 | Green Pepper | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | Covermount | | | |
| Serious Sam II
シリアス サム II | PC | 1.00 | Original | | | |
| Serious Sam II
Крутой Сэм II | PC | 2.066.00 : 59775 | 1C: Kollekciya igrushek | | | |
| Serp i Molot
Серп и Молот | PC | | 1C: Igroteka | | | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| The Settlers: Dziedzictwo Królów
The Settlers: Heritage of Kings | PC | | eXtra Klasyka Next | | | |
| The Settlers: Dziedzictwo Królów: Złota Edycja
The Settlers: Heritage of Kings: Gold Edition | PC | | eXtra Klasyka XK Gold | | | |
| The Settlers: Heritage of Kings | PC | 1.03.0190 | Ubisoft eXclusive / Focus Essential, The Settlers: Heritage of Kings / CSI: Crime Scene Investigation / Rayman 3: Hoodlum Havoc |  | 5003950, ESS626 | |
| The Settlers: Heritage of Kings | PC | 1.01.0163 | Original | | 682011-DVD | |
 | The Settlers: Heritage of Kings: Gold Edition | PC | 1.05.0216 | That's Hot! | | 300006753 | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Original | | 5004220 | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Covermount | | | |
| The Settlers: Narodziny Imperium / Wschodnie Królestwa
The Settlers: Rise of an Empire / The Eastern Realm | PC | | Ubisoft Exclusive | | 300029089 | |
| The Settlers: Narodziny Kultur
The Settlers: Rise of Cultures | PC | 1.0 | Original | | 300026608 | |
| The Settlers: Nasledie Korolej
The Settlers: Наследие Королей | PC | 1.03.0190 | Original | | | |
| The Settlers: Rascvet Imperii
The Settlers: Расцвет империи | PC | | Original | | | |
 | The Settlers: Rise of an Empire
工人物语：帝国崛起 | PC | | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.6.4287 | Covermount, Rerelease | | 300007676 | |
| The Settlers: Rise of an Empire | PC | 1.6.4287 | Ubisoft eXclusive / Focus Essential | | ESS806 | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original, Bundle Version LG OEM | | 300007676, 300007742 | |
| The Settlers: Rise of an Empire | PC | | Software Pyramide | | 300030091 | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.0.4140.0 | Scholastic | | P/N DVD5107350 | |
| The Settlers: Rise of an Empire: Gold Edition
The Settlers: Bâtisseurs d'Empire: Gold Edition | PC | 1.6.4287 | | | 684596-DVD | |
| The Settlers: Rise of an Empire: The Eastern Realm | PC | 1.4.4273 | Original | | 300011555, 300011767 | |
| Seven Kingdoms Conquest | PC | 1.04 | TopSeller | | | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Sezon oxoty
Сезон охоты | PC | | Original | | | |
| Shadow Ops: Red Mercury | PC | | Original | | 1015571 | |
| Shadow Ops: Red Mercury | PC | | Rerelease | | 1019185 | |
| Shadow Wolf Mysteries: Curse of the Full Moon / Bane of the Family | PC | | | | 33425010US | |
| Shadowgrounds | PC | 1.02 | Original | | UGL0001 | |
| Shadowgrounds | PC | | Linux (LGP) | | | |
| Shadowgrounds Survivor | PC | 1.07 | Original |    | WEN1016 | |
 | Shadowgrounds Survivor | PC | finland 1.00 | Special Edition |  | | |
| Shadowgrounds Survivor | PC | 1.06 | Original | | | |
| Shadowgrounds Survivor | PC | 1.07 | Original | | | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| Shadowgrounds Survivor | PC | | Linux (LGP) | | | |
| Shadowgrounds: Survivor | PC | 1.00 | Gry dla Ciebie | | | |
| Shadowrun | PC | 1.0 | Original | | 0307 Part No. X13-37202-01 | |
| Shadowrun | PC | 1.00.0000 | Original | | 0407 Parte n. X13-57732-01 IT | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Shadowrun Chronicles: Boston Lockdown | PC | 12.0.10093 | Cosmi | | DVDC6251 | |
| Shadowrun Returns | PC | 1.2.0 | Original | | | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shan Yu E 2
善與惡2 | PC | 1.0.0.0 | Original | | 1490307 | |
| Shattered Horizon | PC | | Premium Edition | | | |
| Shattered Horizon | PC | | Premium Edition | | | |
| Shattered Suns | PC | 1.0 | Original | | Part # CCS00003-1 | |
| Shattered Union | PC | 1.00x | Sold Out Software | | S0C001010 sov. 3.5 | |
| Shattered Union | PC | 1.00x | Software Pyramide | | | |
