| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | ESPN Golf: Lower Your Score with Tom Kite: Shot Making (Disc 4) | 3DO | 1.0 | Not for Sale |  | SGK-01-3DO | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| A ESPN Let's Go Skiing with Picabo Street. J. Kitt & Holly Flanders | 3DO | 1.0 | Original | | SSK-01-3DO | |
| ESPN Let's Play Beach Volleyball with Karch Kiraly and Karolyn Kirby | 3DO | 1.0 | Original | | SBV-01-3DO | |
| ESPN Let's Play Soccer with John Harkes and Mia Hamm | 3DO | 1.0 | Original | | SSO-01-3DO | |
| ESPN Let's Play Tennis with Tracy Austin | 3DO | 1.0 | Original | | STE-01-3DO |  |
 | The Eye of Typhoon
極超豪拳 극초호권 | 3DO | | Limited Edition | | VIC-PS0001K | |
| The Eye of Typhoon
極超豪拳 극초호권 | 3DO | | Original | | GDT-GA391 | |
 | Ed Bogas' Music Machine
エド・ボーガス ミュージック・マシン | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 30 | | HME-144 | |
| Ed Bogas' Music Machine
エド・ボーガス ミュージック・マシン | FMT | Rev A | FM Towns Soft Collection Kaigai-hen Vol. 30 | | HME-144A | |
| Emit Vol. 1: Toki no Maigo
エミット Ｖｏｌ．１ 「時の迷子」 | FMT | | Original |  | HMF-115 | |
| Emit Vol. 2: Inochigake no Tabi
エミット Ｖｏｌ．２ 「命がけの旅」 | FMT | | Original | | HMF-157 | |
| Emit Vol. 3: Watashi ni Sayonara o
エミット Ｖｏｌ．３ 「私にさよならを」 | FMT | | Original | | HMF-178 | |
| Evolution | FMT | | Original | | DPS-70 | |
| Excellent 10
エクセレント１０ | FMT | | Original | | HMB-201 | |
| Eagle Eye Mysteries in London | MAC | | Original | | 7562 | |
| Eastern Mind: The Lost Souls of Tong Nou | MAC | | Original | | | |
| The Educorp CD Sampler | MAC | | Original | | | |
| The Educorp CD Sampler | MAC | | Original | | | |
| Emit Vol. 1: Toki no Maigo
エミット Ｖｏｌ．１ 「時の迷子」 | MAC | | Original | | KN10-60102 | |
| Enigmo | MAC | | Original | | | |
 | Enemy Engaged: RAH-66 Comanche Versus KA-52 Hokum | MAC | 1.0 | Original |    | | |
| Enemy Territory: Quake Wars | MAC | 1.4 | Original | | 11650-1DDA | |
| Earth Command | CDI | 1.01 | Beta (Testing - Phase 1) | | 810 0072 | |
| Earth Command | CDI | 1.14 | Original | | 810 0072 | |
| Earth Rhythms: Daichi no Hibiki
アース・リズム ～大地の響き～ | CDI | | Sample | | PCIM-00036 | |
| Ecosystems: Nature in Balance
AIMS: Ecosystems: Nature in Balance | CDI | | Original | | 085599 | |
| Elsevier's Interactive Anatomy: Volume 1-I (Paranasal Sinuses & Anterior Skull Base) | CDI | | Original | | | |
| Elsevier's Interactive Anatomy: Volume 2-I (Shoulder Joint & Axilla) | CDI | | Original | | | |
| Elsevier's Interactive Anatomy: Volume 2-II (Hand & Wrist) | CDI | | Original | | | |
| Engineering 5.0 | CDI | | Demo | | | |
| Engineering 6.0 | CDI | | Demo | | | |
 | Ennio Morricone: Vidi Aquam id est Benacum | CDI | | | | VDNA 01 | |
| eScape | CDI | | Original, Head Crash: Limited Edition Triple Pack | | 810 0117 | |
 | Escape from CyberCity | CDI | | Original, Demonstration Disc, Nur für Demonstrationszwecke | | 310-690-071-2, 310690071-2, 690 071-2, 690 0712, 810 0005, 812 0043, 813 0041, 815 0029 | |
 | Everything You Always Wanted to Ask John Hawkins | CDI | | Prototype | | | |
| Everything You Always Wanted to Ask John Hawkins | CDI | | Prototype | | | |
| Everything You Ever Wanted to Know About CD-i | CDI | | For Demonstration Only | | | |
| Evolution (Change through Natural Selection) | CDI | | Original | | 085582 | |
| Exit 7: The Harley-Davidson Experience on CD-i | CDI | | | | | |
| Empire of the Undead | PPC | 1.00 | Original | | | |
| EverQuest for the Pocket PC | PPC | | Original | | 8145EQPPCCD1 | |
 | EasiWriter Pro | ARCH | 8.64 | Original | | | |
| EFF1 Professional Typography 1997 | ARCH | | Original | | | |
