Region | Title | System | Version | Edition | Languages | Serial | Status |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers II | PC | | Demo | | | |
| Session Power Up Kit for DrumMania 2nd Mix / PercussionFreaks 2nd Mix | KS573 | | Original | | 912 *Z A01 | |
| Sesame Street: Ready, Set, Grover! with Elmo: The Videogame | WII | | Original | | RVL-SESE-USA-B0 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Let's Make a Word! | PC | | Original, Software for the fun of it | | KES006 | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Let's Make a Word! | PC | | | | 7418 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the fun of it | | EOA844AE-CD, KES005 | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam HD | XBOX360 | | Promo | | MK-2004 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| The Serious Sam Collection | XBOX360 | | Original | | MK-2010 | |
| Sequence Palladium Premium Digital Novel | PC | | PC Game Bundle | | KGD-06021 | |
| Sequence Palladium Mania Kit: Desktop Accessory シークエンス・パラディウム マニアキット デスクトップアクセサリ | PC | | Original | | WIC-6346 | |
| Sento Monogatari: Sono I 「占都物語」 そのI | PC | | Original | | | |
| Sentient | PC | | Original | | | |
| Senkaku Mondai o Yatchimasu 2 尖閣問題を殺っちます2 | PC | | Original | | | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc 戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senha N. 1 | PC | | | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Seiya Monogatari: Anearth Fantasy Stories 聖夜物語 | PCE | | Bundled with Book (Dengeki PC Engine Special Edition - Taikenban) | | HMD-0004 | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Taikenban Special Disc | | SLPM 80271 | |
| Le Seigneur des Anneaux: Le Retour du Roi | GC | | Original | | DL-DOL-GKLF-FRA | |
| SegaSaturn: Movie Tools: Cinepak for Sega Saturn | SS | | Hybrid Version | | L17-1000 | |
| SegaSaturn: Graphic & Sound Tools for Macintosh | SS | | Original | | N16-1000 | |
| Segare Ijiri せがれいじり | PSX | | Otameshi Disc | | SLPM 80426 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Sega Soccer Slam | XBOX | | Original | | SE-020 | |
| Sega Soccer Slam セガ サッカースラム | GC | | Original | | DL-DOL-GSSJ-JPN | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Saturn Development Tool Kit | PC | | Original | | 610-5750 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Mihon-hin | | 670-10314 | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Racing Classic | SRE | | RingWide | | DVR-0009A | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega PC Special Trydisc Vol. 1 Sega PC すべしゃる トライディスク Vol.1 | PC | | PC Game Bundle | | 670-9986 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | PC Game Bundle | | 670-11970 | |
| Sega PC Collection Vol. 1 | PC | | PC Game Bundle | | 673-04569 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083D | |
| Sega Network Taisen Mahjong MJ5 Evolution セガネットワーク対戦麻雀MJ5 EVOLUTION | SRE | | Original | | DVR-0071 | |
| Sega Network Taisen Mahjong MJ5 セガネットワーク対戦麻雀MJ5 | SRE | | Original | | DVR-0027 | |
| Sega Net Mahjong MJ Arcade セガNET麻雀MJ Arcade | SRE | | Original | | DVR-5055D | |
| Sega GT Online | XBOX | | Beta | | | |
| Sega GT 2002 + JSRF: Jet Set Radio Future 세가 GT 2002 + 젯 셋 라디오 퓨처 · 噴射小子 未來版 | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT 2002 | XBOX | | Demo | | SE-003 | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega Game Honpo: Puyo Puyo セガゲーム本舗 ぷよぷよ | PC | | Original | | | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega E3 2002 Art Disc | PC | | Press Kit | | | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega CD Demo | MCD | | Prototype | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Service: Wydanie Specjalne Alone in the Dark | PC | | | | | |
| Secret Service CD 91 | PC | | | | | |
| Secret Service CD 90 | PC | | | | | |
| Secret Service CD 89 | PC | | | | | |
| Secret Service CD 88 | PC | | | | | |
| Secret Service CD 87 | PC | | | | | |
| Secret Service CD 64 | PC | | | | | |
| Secret Service CD 61 | PC | | | | | |
| Secret Service CD 60 | PC | | | | | |
| Secret Service CD 59 (Strona B) | PC | | | | | |
| Secret Service CD 59 (Strona A) | PC | | | | | |
| Secret Service CD 58 (Strona B) | PC | | | | | |
| Secret Service CD 58 (Strona A) | PC | | | | | |
| Secret Service CD 57 (Strona B) | PC | | | | | |
| Secret Service CD 57 (Strona A) | PC | | | | | |
| Secret Service CD 56 (Strona B) | PC | | | | | |
| Secret Service CD 56 (Strona A) | PC | | | | | |
| Secret Service CD 55 (Strona B) | PC | | | | | |
| Secret Service CD 55 (Strona A) | PC | | | | | |
| Secret Service CD 54 (Strona B) | PC | | | | | |
| Secret Service CD 54 (Strona A) | PC | | | | | |
| Secret Service CD 53 (Strona B) | PC | | | | | |
| Secret Service CD 53 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona B) | PC | | | | | |
| Secret Service CD 52 (Strona A) | PC | | | | | |
| Secret Service CD 51 (Strona A) | PC | | | | | |
| Secret Service CD 51 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona A) | PC | | | | | |
| Secret Service CD 49 (Strona B) | PC | | | | | |
| Secret Service CD 49 (Strona A) | PC | | | | | |
| Secret Service CD 48 (Strona B) | PC | | | | | |
| Secret Service CD 48 (Strona A) | PC | | | | | |
| Secret Service CD 47 (Strona B) | PC | | | | | |
| Secret Service CD 47 (Strona A) | PC | | | | | |
| Secret Service CD 46 | PC | | | | | |
| Secret Service CD 45 | PC | | | | | |
| Secret Service CD 44 (Strona B) | PC | | | | | |
| Secret Service CD 44 (Strona A) | PC | | | | | |
| Secret Service CD 43 | PC | | | | | |
| Secret Service CD 41 | PC | | | | | |
| Secret Service CD 40 | PC | | | | | |
| Secret Service CD 39 | PC | | | | | |
| Secret Service CD 38 | PC | | | | | |
| Secret Service CD 37 | PC | | | | | |
| Secret Service CD 36 | PC | | | | | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| Secret of Video Architecture X68000画面表示仕様の秘密 | X68K | | Original | | | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Files 2: Puritas Cordis | WII | | | | RVL-RZFP-EUR | |
| Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Demo Disk | FMT | | Hibaihin | | HME-921 | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Second Sight | PC | | Bundle Version ASUS OEM | | V468 | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| Seasons Greetings from Philips Media | CDI | | Original | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| SeaBlade | XBOX | | Original | | VU-023 | |
| Sea Rescue | PC | | Nestlé Corn Flakes | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7P-EUR | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84007 | |
| SD Gundam: GGeneration-F (Disc 3) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84006 | |
| SD Gundam: GGeneration-F (Disc 2) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84005 | |
| SD Gundam: GGeneration-F (Disc 1) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84004 | |
| SD Gundam: Gashapon Wars SDガンダム ガシャポンウォーズ | GC | | Taikenban | | DL-DOL-PGPJ-JPN | |
| The Scroll Daughter of Serpents | PC | | Original | | | |
| The Scroll | PC | | | | | |
| Scribblenauts Unlimited (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Screen Fighter Screen Saver スクリーンファイター スクリーンセーバー | PC | | Original | | SRC-00001 | |
| ScreamRide | XBOX360 | | Original | | MS-2726 | |
| Screaming Skies | PC | | Tewi | | Bestell-Nr. 27669 | |
| Screamer Rally | PC | | Covermount | | G02 | |
| Screamer 4x4 | PC | | Covermount | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer | PC | | White Label | | | |
| Screamer | PC | | Sold Out Extreme | | | |
| Scramble Cobra: Premium Version スクランブル・コブラ プレミアム・バージョン | 3DO | | Not for Sale | | FZ-JJ9PSC-5H | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Demonstration-ban | | FZ-JJ9DSP-5G | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| Scrabble CD-ROM | PC | | Original | | 23713-0726 Rev a | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scrabble | PC | | General Mills | | | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| Score International Baja 1000: World Championship Off Road Racing Score International Baja 1000: The Official Game | XBOX360 | | Original | | AV-2083 | |
| Score International Baja 1000: The Official Game | WII | | Original | | RVL-RJCE-USA | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooby-Doo! Unmasked | GC | | Original | | DL-DOL-G5DE-USA | |
| Scooby-Doo! Pierwsze Strachy | PC | | Demo | | | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Les Civilisations Perdues | VFLASH | | Original | | 093085(FR) | |
| Scooby-Doo! Fluch der Folianten | GC | | Original | | DL-DOL-GC3D-NOE | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093083(UK) | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo and the Cyber Chase | PSX | | Demo | | SLUS-90098 | |
| Scooby Doo: Strachy na Lachy | PC | | | | | |
| Science Is Elementary 3 | PSX | | Original | | LSP-990163 … | |
| Science Is Elementary 2 | PSX | | Original | | LSP-990162 … | |
| Science Is Elementary 1 | PSX | | Original | | LSP-990161 … | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| SCI Media Kit: Version: 2 | PC | | Press Kit | | | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | MAC | | Original | | 9227 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| Die Schönsten Hotels der Welt | PHOTO-CD | | Original | | 813 0060 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Schleichfahrt | PC | | Original | | | |
| Schleichfahrt | PC | | | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schiff-Simulator 2008 Ship Simulator 2008 | PC | | Original | | | |
| Scene Xplorer '97 Scene Explorer: From the Beginning into the Future | ACD | | Original | | | |
| Scene Storm | ACD | | | | | |
| Scene It? Luces, Cámara, ¡Acción! Scene It? Bright Lights! Big Screen! | XBOX360 | | Bundled with 4 Controllers | | MS-2098 | |
| A Scene It? Lights, Cameraction! A Scene It? Luci, Camerazione! Il gioco a quiz sul cinema | XBOX360 | | Original | | MS-2098 | |
| A Scene It? Lights, Cameraction | XBOX360 | | Original | | MS-2098 | |
| Scene It? Grandes Éxitos de Taquilla | XBOX360 | | Original | | MS-2144 | |
| Scene It? Ganz großes Kino! | WII | | Original | | RVL-SSCD-NOE-B0 | |
| Scene It? Ganz großes Kino! | XBOX360 | | Original | | WR-2040 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2037 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCE-USA-B0 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| Scene It? Box Office Smash! Scene It? Campione d'Incassi: Nuovissimi filmati e quiz sul cinema | XBOX360 | | Original | | MS-2144 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| The Scene Archive: 1988-1998 | ACD | | Original | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 2) | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 1) | PC | | Press Kit | | | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| Scavenger 4 スカベンジャー4 | FMT | | Demo-ban | | HME-918 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 300202 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCE-USA | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Scan & Teach: Thema 7-12: Klasse 3 | CDI | | Original | | | |
| Scan & Teach: Thema 1-6: Klasse 3 | CDI | | Original | | | |
| Scaler | GC | | Original | | DL-DOL-GKUE-USA | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 2) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 1) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| SBK: Superbike World Championship | XBOX360 | | Original | | CN-2005 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK Generations | XBOX360 | | Original | | LS-2033 | |
| SBK 09: Superbike World Championship | XBOX360 | | Original | | LS-2004 | |
| SBK 08: Superbike World Championship | PC | | Covermount | | | |
| SBK 08: Superbike World Championship | XBOX360 | | Original | | LS-2001 | |
| SBFR the Best 4: PKMN First History | PC | | Original | | SSEB-0055 | |
| SBFR the Best 3: Kirby First History | PC | | Original | | SSEB-0054 | |
| SBFR the Best 2: White | PC | | Original | | SSEB-0041 | |
| SBFR the Best 2: Black | PC | | Original | | SSEB-0042 | |
| Sayonara さよなら 体験版 | PC | | Taikenban | | | |
| Say What You Want | CDI | | Original | | | |
| Savage: The Battle for Newerth | PC | | Bundle Version ASUS OEM | | V471 | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Satsui no Shoumei: In the 1st Degree: Making CD-ROM 殺意の証明 イン ザ ファースト ディグリー メイキングCD-ROM | PC | | Hibaihin | | IP-081M | |
| Satsui no Shoumei: In the 1st Degree (Disc 2) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078B | |
| Satsui no Shoumei: In the 1st Degree (Disc 1) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078A | |
| SAT.1 Swing | PC | | Original | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | Original | | | |
| SAS: Secure Tomorrow | PC | | Covermount | | | |
| SAS: Anti-Terror Force | PC | | | | | |
| Sargon V: World Class Chess サルゴンⅤ | FMT | | Original | | HMD-191 | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| Santa Claus Saves the Earth | PSX | | Original | | SLES-04023 | |
| Santa Claus Is Comin' to Town! | WII | | Original | | RVL-SX5E-USA-B0 | |
| Sansuu Senshi Blaster: Anzan Power de Spot-kun o Sukue! 算数戦士ブラスター 暗算パワーでスポット君を救え! | PC | | Original | | | |
| Sanrio Tiny Park Vol. 2 サンリオ タイニー・パーク Vol.2 | PC | | | | RS-9 | |
| Sanrio Puroland Carnival サンリオピューロランド カーニバル | PC | | | | RS-13 | |
| Sanrio Character Encyclopedia サンリオキャラクター大百科 | PC | | | | R-10 | |
| Sanmi Ittai 三位一体 | PSX | | Taikenban | | SLPM 80065 | |
| Sanitarium | PC | | Demo | | | |
| Sanguozhi V 三國志Ⅴ | PSX | | Zhongwenban | | SCPS 45128 | |
| Sanguozhi IV 三國志Ⅳ | PC | | Original | | | |
| Sanguozhi IV 三國志Ⅳ | PSX | | Original | | SCPS 45003 | |
| Sanguo Zhi Xinghai Fengyun (Disc 2) 三國之星海風雲 | PC | | Original | | | |
| Sanguo Zhi Xinghai Fengyun (Disc 1) 三國之星海風雲 | PC | | Original | | | |
| Sanguo Yinghao 三國英豪 | PC | | Original | | | |
| Sanguo Qunyingzhuan IV Ziliao Sheding 三国群英传Ⅳ 资料设定 | PC | | Bundled with Book | | | |
| Sangokushi Koumeiden 三國志孔明傳 | PC | | Original | | | |
| Sangokushi III 三國志Ⅲ | PCE | | Original | | KOCD3003 | |
| Sangokushi Battlefield 三國志 Battlefield | PC | | βversion | | β-17292 | |
| Sangoku Musou 三國無双 | PSX | | Tentou Taikenban CD-ROM | | SLPM 80085 | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sanae-chan wa Torawarete Shimatta! (Disc 1) さなえチャンは囚われてしまった! | PC | | Original | | | |
| San Francisco Rush The Rock: Alcatraz Edition | PC | | Bundle Version Quantum3D OEM | | 740-0033-01 #QM049 | |
| Samuraj Po-Xi Super Zabawa | PC | | | | | |
| Samurai Warriors: Katana | WII | | Original | | RVL-RS5E-USA | |
| Samurai Warriors: Katana | WII | | Beta | | | |
| Samurai Warriors: Katana | WII | | Original | | RVL-RS5P-EUR | |
| Samurai Warriors 2: Empires | XBOX360 | | Original | | KO-2006 | |
| Samurai Warriors | XBOX | | Original | | KO-006 | |
| Samurai Warriors | XBOX | | Original | | KO-006 | |
| Samurai Shodown Sen | XBOX360 | | Original | | SN-2005 | |
| Samurai Shodown III | PSX | | Original | | SCES-00563 | |
| Samurai Shodown | MCD | | Bundled with Magazine (Demo) | | | |
| Samurai Jack: The Shadow of Aku | GC | | Original | | DL-DOL-GJCE-USA | |
| Samgukji II 2000 Plus 三國志Ⅱ 2000 PLUS | PC | | Original | | | |
| Samba World Cup | ACD | | Original | | | |
| Samantha Swift and the Golden Touch Samantha Swift Bundle | PC | | Original | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| Sam & Max: Season One | WII | | Beta | | | |
| Sam & Max: Season One | PC | | Covermount | | | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YE-USA-B0 | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YP-EUR-B0 | |
| Sam & Max Hit the Road | MAC | | Original | | 8022133 | |
| Salvat Enciclopedia Interactiva | CDI | | Original | | B-44677-96 | |
| Salaryman Champ: Tatakau Salaryman サラリーマンチャンプ たたかうサラリーマン | KS573 | | Original | | A18 JA A02 | |
| Sakura Wars: So Long, My Love | WII | | Original | | RVL-SAKP-UKV-E0 | |
| Sakura Taisen Monogatari: Mysterious Paris: Special Disc サクラ大戦物語 ~ミステリアス巴里~ Special Disc | PC | | Promo | | | |
| Saishuu Densha 最終電車 | PSX | | Taikenban | | SLPM 80215 | |
| Saints Row: The Third: The Full Package (Disc 1) (DLC Installer) | XBOX360 | | Original | | TQ-2213 | |
| Saints Row: The Third | XBOX360 | | Original, The Full Package (Disc 2) | | TQ-2213 | |
| Saints Row: Gat out of Hell | XBOX360 | | Original | | KM-2048 | |
| Saints Row 2 | PC | | Covermount | | | |
| Saints Row (Assets Disk) | PC | | Press Kit | | | |
| Saints Row | XBOX360 | | Classics | | TQ-2001 | |
| Saints Row | XBOX360 | | Demo | | IM-2024 | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Saint Eyes セイントアイズ | PC | | TGL-2000 Series | | | |
| Saint Eyes セイントアイズ | PC | | Shokai Genteiban | | | |
| Sail with Columbus | VIS | | Original | | 25-6181 | |
| Saga: Rage of the Vikings | PC | | Covermount | | | |
| SaGa Frontier 2 | PSX | | Original | | SLES-02118 | |
| Safecracker | WII | | Original | | RVL-RQFE-USA | |
| Safecracker | PC | | Action-Games | | 80271 | |
| Safar'Wii | WII | | Original | | RVL-RD6P-EUR-B0 | |
| Saddle Up with Pippa Funnell: Equestrian Champion | PC | | Original | | 782650-CF | |
| Sacrifice | PC | | Bundle Version MSI OEM | | CD-C951041-MSY4E | |
| Sacrifice (Scapex Tutorial Video) | PC | | Preproduction | | | |
| Sacrifice | PC | | Bundle Version Hewlett Packard OEM | | CD-C951041-PC2E | |
| Sacrifice (Editors Press Kit) | PC | | Press Kit | | | |
| Sacrifice (Disc 3) (Poradnik do Edytora Scapex) | PC | | Original | | | |
| Sacrifice | PC | | Bundle Version ASUS OEM | | CD-C951041-AS2E | |
| Sacred Plus (Disc 1) | PC | | Big Bytes | | | |
| The Sacred Mirror of Kofūn (Disc 3) | PC | | | | CKOF1096-3A | |
| The Sacred Mirror of Kofūn (Disc 2) | PC | | | | CKOF1096-2A | |
| The Sacred Mirror of Kofūn (Disc 1) (Installation) | PC | | | | CKOF1096-1A | |
| Sacred 2: Złota Edycja (Dysk 1) | PC | | Premium Games | | | |
| Sacred 2: Złota Edycja (Dysk 2) | PC | | Premium Games | | | |
| Sacred 2: Złota Edycja (Bonus Disc) | PC | | Premium Games | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Digital Press-Kit: Games Convention 2008) | PC | | Press Kit | | | |
| Sacred (Disc 2) | PC | | | | | |
| Sacred (Disc 1) | PC | | | | | |
| Sacra Terra: Angelic Night | PC | | Original | | | |
| Sabre Team | CD32 | | Original | | | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Sable Maze: Sullivan River / Norwich Caves | PC | | | | 33471010US | |
| Sable Maze: Forbidden Garden & Twelve Fears | PC | | Original | | 33528010US | |
| Saban's Power Rangers: Time Force | PC | | Original | | | |
| Saban's Power Rangers Zeo Versus the Machine Empire | PC | | Original | | | |
| SAAR + AMOK PD CD-ROM Überarbeitete Version 12/93 | ACD | | Original | | | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| S²: Silent Storm (Disc 1) | PC | | Gold Edition | | ROSILENTST0007lab1 | |
| S.T.O.R.M. (Disc 1) | PC | | Original | | A541W3GD[1] | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Clear Sky (Assets) | PC | | Press Kit | | | |
| S.C.A.R.S. | PSX | | Demo | | SLED-01415 | |