| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Serious Sam: Złota Edycja (Disc 1) | PC | | Kolekcja Klasyki |  | CENEGA 395a/PCCD-ROM/2006 |  |
| Serious Sam: Złota Edycja (Disc 2) | PC | | Kolekcja Klasyki | | CENEGA 395b/PCCD-ROM/2006 | |
 | Serp i Molot (Disc 1)
Серп и Молот | PC | | 1C: Igroteka |  | | |
| Serp i Molot (Disc 2)
Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 3)
Серп и Молот | PC | | 1C: Igroteka | | | |
 | The Serpent of Isis: The First 2 Chapters
The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
 | Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
 | Serve & Volley | PC | | Telstar Fun & Games |  | TFGD 2178/4 | |
 | Sesame Street Kazu Asobi: A Visit to Sesame Street: Numbers
セサミストリート かずあそび | CDI | | Original | | PCIM-00013 | |
| Sesame Street Moji Asobi: A Visit to Sesame Street: Letters
セサミストリート もじあそび | CDI | | Original | | PCIM-00012 | |
| Sesame Street Search & Learn Adventures | PC | | software for the fun of it! | | | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the Fun of It! | | EOA844AE-CD, KES005 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Sesame Street Sports | PSX | | Original | | SLUS-01180 | |
| Sesame Street Toddler | PC | | Adventure Workshop Tots | | 32180-CD1 v1.0 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's Art Workshop | PC | | Software for the Fun of It! | | KES186 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original | | SLES-02510 | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original, Twin Pack | | SLUS-00621 … | |
| Sesame Street: Elmo's Number Journey | PSX | | Original | | SLES-02511 | |
| Sesame Street: Elmo's Number Journey | PSX | | Original, Twin Pack | | SLUS-00622 … | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
 | Sesame Street: Elmo's World | PC | | Original | | 2231A | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Let's Make a Word! | PC | | Original | | 7418 | |
| Sesame Street: Let's Make a Word! | PC | | Software for the Fun of It! | | HT99200 | |
| Sesame Street: Let's Make a Word! | PC | | Software for the Fun of It! | | KES006 | |
| Sesame Street: Let's Make a Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Let's Make a Word! | PC | | Original | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Music Maker | PC | | Original | | | |
| Sesame Street: Numbers
セサミ・ストリート ～ナンバーズ～ | 3DO | | Original |  | FZ-SJ1664 | |
| Sesame Street: Numbers
Улица Сезам: Учись считать | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | 3DO | | Original | | | |
| Sesame Street: Preschool
Улица Сезам: Элмо готовит в школу | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: The Adventures of Elmo in Grouchland | PC | | Original | | 24138-0919 | |
| Sesamstrasse: Auf die Krümel, fertig, los! | PC | | Rerelease |  | GSL854AG-CD | |
 | Session Power Up Kit for DrumMania 2nd Mix / PercussionFreaks 2nd Mix | KS573 | | Original | | 912 *Z A01 | |
| Sethi und das Geheimnis der Neandertaler | PC | | Rerelease | | | |
| Sethi: Abenteuer im Mittelalter
National Geographic: Sethi: Abenteuer im Mittelalter | PC | | Original | | | |
| The Settlers II | PC | | Demo | | | |
| The Settlers II: 10-lecie
The Settlers II: 10th Anniversary | PC | | Original | | | |
| The Settlers II: 10-lecie
The Settlers II: 10th Anniversary | PC | | eXtra Klasyka Next, Złota Edycja (eXtra Klasyka XK Hit) | | | |
| The Settlers II: 10-lecie: Wikingowie
The Settlers II: 10th Anniversary: The Vikings | PC | | eXtra Klasyka XK Dodatek | | | |
| The Settlers II: 10-lecie: Wikingowie
The Settlers II: 10th Anniversary: The Vikings | PC | | Złota Edycja (eXtra Klasyka XK Hit) | | | |
| The Settlers II: 10th Anniversary | PC | | Original |    | 5004880 | |
| The Settlers II: 10th Anniversary
Die Siedler II: Die nächste Generation | PC | | Gold Edition (Software Pyramide) | | 300025385 | |
| The Settlers II: 10th Anniversary: Vikings
Die Siedler II: Die nächste Generation: Wikinger | PC | | Gold Edition (Software Pyramide) | | 300025389 | |
 | Settlers II, The: Veni, Vidi, Vici | PC | | Budget | | MMICDR 5803 | |
 | The Settlers III (Disc 1) | PC | | Big Bytes | | RED0807/1 | |
| The Settlers III (Disc 2) | PC | | Big Bytes | | RED08070/2 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers III: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
 | The Settlers IV | PC | | Original | | SORO 459 992.02.0 | |
 | The Settlers IV | PC | | Original | | | |
| The Settlers IV
The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Original | | | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Gold Edition | | | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Złota Edycja | PC | | Nowa eXtra Klasyka | | | |
| The Settlers | PC | | Rerelease | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | eXtra Klasyka | | | |
 | The Settlers | PC | | PC Best Buy Pocket | | 900813 | |
| The Settlers: Heritage of Kings: Gold Edition (Legends Expansion Disc) | PC | | That's Hot! | | 5004531 | |
| Setup Utility for DTL-H1500 (Version 1.1) | PSX | | Original | | | |
| Seven Games of the Soul (Disc 1)
Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2)
Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3)
Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 4)
Faust | PC | | Original | | | |
| The Seven Gates of Jambala | CD32 | | Original | | | |
| Seven Kingdoms | PC | | Play the Games Vol. 1 | | | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Original | | | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Cool Games | | | |
| Seven Kingdoms: Ancient Adversaries | PC | | | | | |
| Seven Kingdoms: Artwork | MAC | | Art Assets | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
 | Seven Years War 2 + Joseonui Bangyeok
임진록 ２ ＋ 조선의 반격 | PC | | Hapbon |  | | |
 | The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 1)
第七封印：魔神甦醒 | PC | | Original |  | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 2)
第七封印：魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 3)
第七封印：魔神甦醒 | PC | | Original | | | |
| Sewer Shark | MCD | | Original | | T-93015-50 | |
