Region | Title | System | Version | Edition | Languages | Serial | Status |
| Spy Fox in "Cheese Chase" | PC | | Original | | | |
| Spy Fiction 스파이 픽션 | PS2 | 1.00 | Original | | SLKA 25007 | |
| Spud! (Disc 2) | PC | | Original | | | |
| Spud! (Disc 1) | PC | | Original | | | |
| Sprint Cars | WII | | Original | | RVL-SN8P-EUR-B0 | |
| Springy | PC | | Original | | | |
| Springdale Springdale Riding Adventures | PS2 | 1.01 | Original | | SLES-55610 | |
| Sprill: Wodne Przygody | PC | | | | | |
| Spriggan: Lunar Verse スプリガン ~ルナ・ヴァース~ | PSX | | Original | | SLPS 02117 | |
| SPRay | WII | | Original | | RVL-RYIE-USA | |
| SPRay | WII | | Original | | RVL-RYIP-EUR-B0 | |
| SPQR: The Empire's Darkest Hour | PC | | Original | | | |
| SPQR: The Empire's Darkest Hour | PC | | Hemming All Stars | | | |
| SPQR: The Emperor's Darkest Hour | PC | | Original | | MMICDR 5188 | |
| Spot Goes to Hollywood スポット・ゴーズ・トゥー・ハリウッド | PSX | | Original | | SLPS 00394 | |
| Spot Goes to Hollywood | SS | 1.400 | Original | | T-7001H-50 | |
| Spot Goes to Hollywood | PSX | | Original | | SLES-00330 | |
| SportzFreakz | PC | 1.0 | Original | | | |
| Sportweek Player Manager 2001 | PSX | | Original | | SLES-03569 | |
| Sportweek Player Manager 2000 | PSX | | Original | | SLES-02616 | |
| Sportsman's Paradise II | PC | 1.0 | Original | | P/N 4-19599CDSL | |
| Sports: Football | CD32 | | | | | |
| Sports Wurx 1 | PC | | Original | | CDO226 | |
| Sports Jam | DC | 1.001 | Original | | T-44304N | |
| Sports Jam スポーツ・ジャム | DC | 1.005 | Original | | HDR-0153 | |
| Sports Jam スポーツ・ジャム | NAOMI | 1.005 | Original | | GDS-0003 | |
| Sports Island Freedom | XBOX360 | | Original | | HU-2015 | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Champions 2 | PS3 | 01.00 | Original | | BCES-01599 | |
| Sports Champions 2 | PS3 | 01.00 | Original | | BCKS 10231 | |
| Sports Champions 2 スポーツチャンピオン2 | PS3 | 01.00 | Original | | BCJS 30086 | |
| Sports Challenge Pack 2 | PC | | Encyclopedia Games 2009-10 Deluxe Edition | | | |
| Sports Car GT | PC | 1.52US | CD-ROM Classics | | 1187207 | |
| Sports Car GT | PC | 1.52m | Bundle Version OEM | | | |
| Sports Car GT | PSX | EDC | EA Classics | | SLES-01916 | |
| Sports Car GT | PC | 1.52m | Play the Games Vol. 3 | | | |
| Sports Car GT | PC | 1.52m | EA Classics | | WWG08801952D | |
| Sports Car GT | PSX | | Original | | SLES-01915 | |
| Sportowe Zmagania bez Wysiłku i Biegania | PC | | | | | |
| Spore: Kimi ga Tsukuru Hero スポア キミがつくるヒーロー | WII | | Original | | RVL-RQOJ-JPN-B0 | |
| Spore: Creature Creator Лаборатория существ Spore | PC | 1.0 | Original | | MXX09205856D | |
| Spore スポア | PC | 1.0 | Original | | 15352EPWNJP | |
| Spore | PC | 1.1.0.338 | Original | | 1535207 | |
| Spore | PC | 1.1.0.338 | Galactic Edition | | MXEX9206217D | |
| Spore | PC | | EA Classics | | | |
| Spore | PC | | Original | | MXX09205658D/ANZ | |
| Spooky Castle | PC | 1.0 | Original | | 11-2057-10 SPC | |
| Spokojnye igry: krug, shashki, shaxmaty, ugolki i... Спокойные игры: круг, шашки, шахматы, уголки и... | PC | | Original | | | |
| Split/Second: Velocity | PS3 | 01.01 | Original | | BLES-00781 | |
| Split/Second: Velocity | XBOX360 | | Original | | BV-2023 | |
| Split/Second: Velocity | PC | | Original | | P_32701_03A_PL | |
| Split/Second Split/Second: Velocity | XBOX360 | | Original | | BV-2023 | |
| Split/Second | PSP | 1.00 | Original | | ULUS-10513 | |
| Split/Second スプリットセカンド | PSP | 1.04 | Original | | ULJM 05812 | |
| Split/Second スプリットセカンド | PS3 | 01.00 | Original | | BLJM 60251 | |
| Split/Second | PS3 | 01.01 | Sample | | BCAS 20192 | |
| Split Screen Soccer Managers | PC | | Soccer Superstars | | | |
| Splatterhouse スプラッターハウス | FMT | | Ving Vol. 13 | | HMD-146 | |
| Splatter Master | PS2 | 1.01 | Original | | SLES-53368 | |
| Splatt! | PC | | Original | | | |
| Splashdown 2: Rides Gone Wild | PS2 | 1.02 | Original | | SLES-51681 … | |
| Splashdown 2: Rides Gone Wild | PS2 | 1.02 | Original | | SLES-51925 … | |
| Splashdown | PS2 | 2.01 | Original | | SLUS-20223 | |
| Splashdown | XBOX | | Original | | IG-027 | |
| Splashdown スプラッシュダウン | PS2 | 1.01 | Original | | SLPM 65113 | |
| Splashdown | XBOX | | Original | | IG-027 | |
| Spirou | PC | | Promo | | SPIROM65511 | |
| Spirits of Mystery: Amber Maiden | PC | | BlackLime Games | | BLG022/D | |
| Spirits & Spells | GC | | Original | | DL-DOL-G2PE-USA | |
| The Spirit of the Wolf | WII | | Original | | RVL-SLPP-EUR-B0 | |
| Spirit of Speed 1937 | DC | 1.001 | Original | | T-8118N | |
| Spirit of Speed 1937 スピリット オブ スピード 1937 | DC | 1.000 | Original | | T-8102M | |
| Spirit of Speed 1937 | PC | 1.0.13 | Game-Hits 1 | | | |
| Spirit of Speed 1937 | DC | 1.002 | Original | | T-8117D-50 | |
| Spirit of Excalibur | PC | | Original | | CDAC 013900 | |
| Spinout | PSP | 1.02 | PSP Essentials | | ULES-00693 … | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi: Roy Ver. Spinnaker Typing Collection 鋼の錬金術師 ロイver. | PC | | Original | | | |
| Spinnaker Typing Collection: Hagane no Renkinjutsushi Spinnaker タイピングコレクション 鋼の錬金術師 | PC | 1.01 | Original | | | |
| Spin Busta | PC | 1.0 | Original | | GS0003 | |
| Spikeout: Battle Street | XBOX | | Original | | SE-041 | |
| Spikeout: Battle Street スパイクアウト バトルストリート | XBOX | | Original | | SE-041 | |
| Spikeout: Battle Street | XBOX | | Original | | SE-041 | |
| Spike: The Hedgehog | PC | | Covermount | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Original | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Dice | | DCG 012965 | |
| Spike: The Hedgehog | PC | 1.0.0.1 | | | APWCDR1033 | |
| Spielen mit Freundin | PC | | Original | | | |
| Spielekiste 2 | ACD | | Original | | | |
| Spiele für Windows 7, XP & Vista | PC | | Software Pyramide | | | |
| Spiel des Lebens | PC | | Original | | | |
| The Spiderwick Chronicles | PS2 | 1.00 | Original | | SLUS-21716 | |
| The Spiderwick Chronicles | PC | 1.0 | Original | | S7270810 | |
| The Spiderwick Chronicles | WII | | Original | | RVL-R48E-USA | |
| The Spiderwick Chronicles | XBOX360 | | Bundled with Audiobook | | VU-2022 | |
| The Spiderwick Chronicles | WII | | Original | | RVL-R48P-EUR | |
| Spider: The Video Game | PSX | | Original | | SLES-00682 | |
| Spider: The Video Game | PSX | | Original | | SLES-00681 | |
| Spider: The Video Game | PSX | | Original | | SLES-00117 | |
| Spider-Man: Web of Shadows: Amazing Allies Edition | PS2 | 1.01 | Original | | SLUS-21822 | |
| Spider-Man: Web of Shadows | XBOX360 | | Original | | AV-2069 | |
| Spider-Man: Web of Shadows | PC | 1.0 | Original | | 33211.101.EU | |
| Spider-Man: Web of Shadows | PS3 | 01.00 | Original | | BLES-00392 | |
| Spider-Man: Web of Shadows | XBOX360 | | Original | | AV-2069 | |
| Spider-Man: The Sinister Six Spider-Man: Die Gnadenlosen Sechs | PC | | Original | | | |
| Spider-Man: Shattered Dimensions | PC | | Original | | 33355101US | |
| Spider-Man: Shattered Dimensions Spider-Man: Dimensions | PC | | Original | | 33355101EU | |
| Spider-Man: Friend or Foe | PSP | 1.00 | Original | | ULUS-10318 | |
| Spider-Man: Friend or Foe | WII | | Original | | RVL-RFOE-USA | |
| Spider-Man: Friend or Foe | PC | | Original | | 33167.101.US | |
| Spider-Man: Friend or Foe | XBOX360 | | Original | | AV-2042 | |
| Spider-Man: Friend or Foe Spider-Man: Allié Ou Ennemi / Spider-Man: Amigo o Enemigo | PSP | 1.01 | Original | | ULES-00900 | |
| Spider-Man: Friend or Foe | WII | | Original | | RVL-RFOX-EUR | |
| Spider-Man: Friend or Foe | WII | | Original | | RVL-RFOP-UKV | |
| Spider-Man: Friend or Foe | XBOX360 | | Original | | AV-2042 | |
| Spider-Man: Freund oder Feind | PSP | 1.01 | Original | | ULES-00901 | |
| Spider-Man: Edge of Time | PS3 | 01.00 | Original | | BLES-01291 | |
| Spider-Man: Angriff der Super-Schurken | VFLASH | | Original | | 093064(GER) | |
| Spider-Man 3 | PS2 | 2.00 | Greatest Hits | | SLUS-21552 | |
| Spider-Man 3 | PS3 | 01.00 | Original | | BLUS-30031 | |
| Spider-Man 3 | PS3 | 01.00 | Collector's Edition | | BLUS-30030 | |
| Spider-Man 3 | PC | | Original | | 33121.101.US | |
| Spider-Man 3 Человек-паук 3 | PC | | Original | | | |
| Spider-Man 3 스파이더-맨 3 | PS2 | 1.00 | Original | | SLKA 25385 | |
| Spider-Man 3 스파이더-맨 3 | PS3 | 01.00 | Original | | BLKS 20020 | |
| Spider-Man 3 スパイダーマン3 | PS2 | 1.02 | Original | | SLPS 25823 | |
| Spider-Man 3 スパイダーマン3 | WII | | Original | | RVL-RS3J-JPN | |
| Spider-Man 3 | WII | Rev 1 | Original | | RVL-RS3P-UKV | |
| Spider-Man 3 | PS3 | 01.02 | Collector's Edition | | BLES-00062 | |
| Spider-Man 3 | PS3 | 01.02 | Original | | BLES-00056 | |
| Spider-Man 3 | PS3 | 01.02 | Collector's Edition | | BLES-00061 | |
| Spider-Man 3 | XBOX360 | | Original | | AV-2018 | |
| Spider-Man 3 | WII | | Original | | RVL-RS3X-EUR | |
| Spider-Man 3 | PC | | Original | | 33121.101.EU | |
| Spider-Man 2: The Game | PC | | Covermount | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.GM | |
| Spider-Man 2: La Revanche d'Electro | PSX | | Platinum | | SLES-03624 … | |
| Spider-Man 2: Enter: Electro スパイダーマン2 ~エンター:エレクトロ~ | PSX | | Original | | SLPM 87073 | |
| Spider-Man 2: Enter: Electro | PSX | | Original | | SLES-03623 | |
| Spider-Man 2 スパイダーマン2 | PS2 | 1.02 | Taito Best | | SLPM 66121 | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2I-ITA | |
| Spider-Man 2 | XBOX | | Classics | | AV-043 | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2D-NOE | |
| Spider-Man 2 | GC | | Original | | DL-DOL-GK2F-FRA | |
| Spider-Man | MAC | | Original | | | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man | GC | Rev 1 | Player's Choice | | DL-DOL-GSME-USA | |
| Spider-Man | XBOX | Rev 1 | Platinum Hits | | AV-006 | |
| Spider-Man | DC | 1.000 | Original | | T-13008N | |
| Spider-Man | PS2 | 2.01 | Platinum | | SLES-50965 … | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50965 | |
| Spider-Man | PSX | | Platinum | | SLES-02890 … | |
| Spider-Man 스파이더맨 | XBOX | | Original | | AV-006 | |
| Spider-Man スパイダーマン | PS2 | 1.01 | Original | | SLPM 65205 | |
| Spider-Man スパイダーマン | GC | | Original | | DL-DOL-GSMJ-JPN | |
| Spider-Man スパイダーマン | XBOX | | Original | | CC-010 | |
| Spider-Man | PSX | | Platinum | | SLES-02889 … | |
| Spider-Man | XBOX | Rev 1 | Classics | | AV-006 | |
| Spider-Man | PS2 | 1.00 | Platinum | | SLES-50814 … | |
| Spider-Man | GC | | Original | | DL-DOL-GSMD-NOE | |
| Spider-Man | PSX | | Original | | SLES-02888 … | |
| Spider-Man | PS2 | 1.00 | Original | | SLES-50813 | |
| Spider-Man | PS2 | 1.00 | Platinum | | SLES-50813 … | |
| Spider-Man | PSX | | Platinum | | SLES-02887 … | |
| Spider-Man | GC | | Original | | DL-DOL-GSMF-FRA | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.UK | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.UK | |
| Spider-Man | GC | Rev 1 | Player's Choice | | DL-DOL-GSMP-UKV | |
| Spider-Man | XBOX | Rev 1 | Classics | | AV-006 | |
| Spider-Man | DC | 1.000 | Original | | T-13011D-50 | |
| Spider-Man | XBOX | | Original | | AV-006 | |
| Spice World | PSX | | Original | | SCES-01234 | |
| Spice World | PSX | | Original | | SCES-01232 | |
| Spice World | PSX | | Original | | SCES-01231 | |
| Spice and Wolf VR 狼と香辛料VR | PC | | Kickstarter (Deluxe Edition) | | | |
| Sphinx and the Cursed Mummy | PS2 | 1.00 | Original | | SLUS-20482 | |
| Sphinx and the Cursed Mummy | XBOX | | Original | | TQ-035 | |
| Sphinx and the Cursed Mummy 스핑크스와 저주받은 미이라 | PS2 | 1.00 | Original | | SLKA 25018 | |
| Sphinx and the Cursed Mummy 스핑크스와 저주받은 미이라 | XBOX | | Original | | TQ-035 | |
| Sphinix Gold | PC | | Original | | ROK 04 Art.-Nr. 6623 | |
| Sphere Racer | PC | | Original | | | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| Spełnij Marzenia: Gra Piłkarska Pepsi | PC | | | | | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Speltajm: Djungelns kojigaste CD-ROM | PC | | Original | | | |
| Spells of Gold | PC | | Original | | CENEGA 163/2003 | |
| Spelling: 'SATS' Key Stage 2 | PC | 1999.12.1.1 | Original | | | |
| Spelling Challenges and More! | PSP | 1.00 | Original | | ULUS 10255 | |
| SpellForce: Złota Edycja (Disc 4) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 3) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Zakon Świtu: Złota Edycja | PC | 1.53.65731 | eXtra Klasyka neXt | | | |
| SpellForce: Universe (Disc 2) | PC | 2.00 | Original | | DVD563CD | |
| SpellForce: Universe (Disc 1) | PC | 1.52 | Original | | DVD564CD | |
| SpellForce: The Order of Dawn (Disc 2) | PC | | Covermount | | ROSPELLFOR0003LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) | PC | | Covermount | | ROSPELLFOR0003LAB1 | |
| SpellForce: The Order of Dawn (Disc 3) (Install CD3) | PC | | Limited Edition | | ROSPELLFOR0012LAB3 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab2 | |
| SpellForce: The Order of Dawn (Disc 2) (Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | | Limited Edition | | ROSPELLFOR0012LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab1 | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | | Limited Edition | | ROSPELLFOR0012LAB1 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: Platinum Edition | PC | 1.5 | SpellForce Universe | | JOW 009PC LAB1 | |
| SpellForce: Gold Edition (Disc 3) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 2) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 1) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition | PC | 1.53.65731 | Original | | | |
| SpellForce 2: Shadow Wars | PC | 1.02 Build #111632 | Original | | | |
| SpellForce 2: Shadow Wars | PC | 1.0 | Bundle Version OEM | | G-SF02 | |
| SpellForce 2: Shadow Wars | PC | 1.02 Build #111632 | Bundle Version Leadtek OEM | | Y03G0009 | |
| SpellForce 2: Gold Edition | PC | 2.00 | SpellForce Universe | | JOW 009PC LAB2 | |
| SpellForce 2: Gold Edition | PC | 2.01 | Original | | | |
| SpellForce | PC | 1.52.64763 | Platinum Edition | | 11121-1DDA | |
| SpellForce 魔幻世紀 | PC | 1.54.71521 | Original, 3 in 1 Nüshen Zuanshi Heji | | | |
| Spellcross: L'Ultima Battaglia | PC | | CD-ROM Classic Collection 7 | | | |
| Spellcasting: Party Pak | PC | 1.0 | Original | | | |
| Spellbound Party | WII | | Original | | RVL-SPBP-EUR-B0 | |
| Het Speelhuis van Muis | PC | | Original | | | |
| Speel Bridge 5 | PC | | Original | | | |
| Speel Bridge 4 | PC | | Original | | | |
| Speedy Zone 2 | PC | | Original | | 100-4045 | |
| Speedy Eggbert II Speedy Eggbert 2 | PC | 1.0 | Original | | | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| Speedy Eggbert | PC | 1.1 | Original | | 02-9703-10 | |
| Speedway 2000 | PC | | Original | | | |
| Speedster | PC | | Dice | | DCG 005813, DMM 005837 | |
| Speedster | PC | | Original, Argentum Collection | | | |
| SpeedRage | PC | 1.10 | 2in1 Pack | | | |
| SpeedRage (Game Disk) | PC | 1.10 | Original | | TFGD2159 | |
| SpeedRage (Slave Disk) | PC | 1.10 | Original | | TFGD2159 | |
| Speedlink Competition Pro USB: Sports Tournament Edition | PC | | Bundle Version Speedlink OEM | | SL-6603-SPORTS-EU | |
| Speedboat GP | PS2 | 1.01 | Original | | SLES-54074 | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | 0.9.9.0 | Covermount | | | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speedboat Attack | PC | 0.9.9.0 | Original | | | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speedball 2: Tournament | PC | | Original | | | |
| Speed Zone | WII | | Original | | RVL-RZSE-USA-B0 | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Speed Thief | PC | 1.0 | Original | | | |
| Speed Racer スピード・レーサー | WII | | Original | | RVL-R3PJ-JPN | |
| Speed Racer Speed Racer: The Videogame | PS2 | 1.01 | Original | | SLES-55075 | |
| Speed Pack Streets of Moscow | Classic Car Racing | PC | | Original | | | |
| Speed Machines | PSX | | Original | | SLES-03930 | |
| Speed Kings | PS2 | 1.00 | Original | | SLUS 20584 | |
| Speed Kings | GC | | Original | | DL-DOL-GDCE-USA | |
| Speed Kings | XBOX | | Original | | AC-011 | |
| Speed Haste | PC | | Rerelease | | | |
| Speed Haste | PC | | Pocket Price Games | | | |
| Speed Freak | PC | | Covermount | | | |
| Speed Devils: Online Racing | DC | 1.002 | Original | | T-17718N | |
| Speed Devils: Online Racing | DC | 1.003 | Original | | T-17713D-50 | |
| Speed Devils | DC | 1.004 | Original | | T-17702N | |
| Speed Devils | DC | 1.004 | Original | | T-17702D-50 | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Original | | Ref: 65702162 | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Covermount | | | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Ubi Soft Classique | | | |
| Speed 2 | WII | | Bundled with Wii Wheel | | RVL-SQPP-EUR-B0 | |
| Speed | WII | | Original | | RVL-SPEE-USA-B0 | |
| Speed | WII | | Original | | RVL-SPEP-EUR-B0 | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Spectre VR CD | MAC | | Original | | | |
| Spectre VR | PC | 1.07wp | Ultimate Game Collection | | | |
| Spectre VR | PC | 1.05 | Original | | | |
| Spectral vs. Generation スペクトラル VS ジェネレーション | PS2 | 1.02 | Original | | SLPM 62727 | |
| Spectral vs. Generation | PSP | 1.02 | Original | | ULES-00757 | |
| Spectral Souls: Resurrection of the Ethereal Empires | PSP | 1.00 | Original | | ULUS-10076 | |
| Spectral Force: Radical Elements スペクトラルフォース ラジカルエレメンツ | PS2 | 1.06 | Original | | SLPM 65669 | |
| Spectral Force 3: Innocent Rage | XBOX360 | | Original | | IF-2001 | |
| Spectral Force 3: Innocent Rage スペクトラルフォース3 ~イノセント レイジ~ | XBOX360 | | Original | | IF-2001 | |
| Spectral Force 3 | XBOX360 | | Original | | AT-2003 | |
| Specnaz: proekt Volk (Disc 2) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: proekt Volk (Disc 1) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: Antiterror. Missija na Balkanah (Disc 1) Спецназ: Антитеррор. Миссия на Балканах | PC | | Original | | | |
| Special Jinsei Game Special 人生ゲーム | GC | | Original | | DL-DOL-GLIJ-JPN | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Special Forces | PS2 | 1.00 | Original | | SLES-54591 | |
| Special Forces | PC | 1.00 | Hit Squad: Regenerator | | REGEN020 | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
| Speccy Classix '98 Speccy Classix 1998 | PC | | | | | |
| Spec Ops: The Line | PC | | Premium Edition | | 41152-1 | |
| Spec Ops: The Line スペックオプス ザ・ライン | PS3 | 01.01 | Original | | BLJS 10171 | |
| Spec Ops: The Line | PC | | Original | | 5055550/DVD | |
| Spec Ops: Rangers Lead the Way | PC | 1.0 | Original | | CD-RC008 | |
| Spec Ops: Ranger Assault | PC | | Covermount | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | 2.5 | Red Fly | | | |
| Spec Ops: Ranger Assault | PC | | Original | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Extreme | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops II: Omega Squad | DC | 1.008 | Original | | T-41704N | |
| Spec Ops II: Omega Squad | DC | 1.002 | Original | | T-45004D-50 | |
| Spec Ops II: Green Berets | PC | 1.00.000 | Original | | CD-RG-003 | |
| Spearhead | PC | | Covermount | | | |
| Spearhead סימולטור טנקים | PC | 1.0.0.1 | Original | | | |
| Spearhead | PC | | Original | | | |
| Spearhead | PC | | Pocket Price | | | |
| Spearhead | PC | | Original | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Spawn: Unmei no Kusari SPAWN ~運命の鎖~ | PS2 | 1.01 | Original | | SLPS 25370 | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-1216N | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-36816D-50 | |
| Spawn: Armageddon | PS2 | 1.00 | Original | | SLUS-20707 | |
| Spawn: Armageddon | GC | | Original | | DL-DOL-GPWE-USA | |
| Spawn: Armageddon | XBOX | | Original | | NM-012 | |
| Spawn: Armageddon | PS2 | 1.00 | Original | | SLES-52326 … | |
| Spawn: Armageddon | XBOX | | Original | | NM-012 | |
| Spawn: Armageddon | GC | | Original | | DL-DOL-GPWP-EUR | |
| Spaß am Turnierreiten Equestriad 2001 | PC | | Original | | | |
| Spartan: Total Warrior | PS2 | 1.02 | Original | | SLUS-21212 | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAE-USA | |
| Spartan: Total Warrior | XBOX | | Original | | SE-139 | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAD-NOE | |
| Spartan: Total Warrior | GC | | Original | | DL-DOL-GWAF-FRA | |
| Spartan: Total Warrior | XBOX | | Original | | SE-132 | |
| Spartan: Kodai Greece Eiyuuden スパルタン 古代ギリシャ英雄伝 | PS2 | 1.02 | Original | | SLPM 66444 | |
| Spartan XX スパルタン イグゼクス | PC | | Original | | | |
| Spartan | PC | 1.013 | Covermount | | | |
| Spartan | PC | | Sold Out Software | | | |
| Sparrow Garden: Namco Mahjong ナムコマージャン スパローガーデン | PSX | | Original | | SLPS 00074 | |
| Sparkling Feather スパークリング・フェザー | PC-FX | | Original | | FXNHE739 | |
| Spacetanks | PC | 1.0 | Pepper Games | | | |
| Spaceship Warlock | PC | 1.1.3 | Original | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| SpaceHaste 2 SpaceHaste | PC | 1.32 | TopWare Just 4Fun | | | |
| SpaceHaste 2 SpaceHaste: The Next Levels | PC | 2.001 | Covermount | | | |
| SpaceHaste 2 | PC | | Original | | | |
| SpaceHaste BGamer 070 (Disc 2) | PC | | Covermount | | | |
| Spaceforce: Rogue Universe | PC | 1.0.0.0 | Original | | ROSPACEFOR0002LAB | |
| Spaceforce: Rogue Universe | PC | 1.0.0.0 | Original | | ROSPACEF0R0000LAB | |
| Spaceforce: Captains | PC | 1.0.0.0 | Original | | ROSPACEFOR0005LAB | |
| Spaceforce: Captains | PC | 1.0.0.0 | Original | | JOW 003PC | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Space-Dude: Der Retter des Universums | PC | | Original | | | |
| Space War Attack | PS2 | 1.01 | Original | | SLES-53915 | |
| Space Tripper | PC | | Original | | APWCDR1014 | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Space Station Manager Космоград | PC | 1.2.1 Rus | Original | | | |
| Space Sirens | PC | | Original | | SKU: UN017 | |
| Space Siege | PC | | Original | | SEGA-PC076 | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Rider | PSX | | Original | | SLES-04126 | |
| Space Rangers 2: Reboot | PC | | Power Games | | | |
| Space Rangers / Space Rangers 2: Dominators | PC | | | | | |
| Space Rangers | PC | 1.7.2 | Cinemaware Marquee | | 02-1506-12 | |
| Space Raiders 스페이스 레이더스 VER.2 | PS2 | 1.00 | Original | | SLKA 15002 | |
| Space Raiders 스페이스 레이더스 | GC | | Original | | DL-DOL-GIJK-KOR | |
| Space Raiders スペースレイダース | PS2 | 1.01 | Original | | SLPM 62275 | |
| Space Raiders スペース レイダース | GC | | Original | | DL-DOL-GIJJ-JPN | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest I: Roger Wilco in the Sarien Encounter | PC | | Kixx XL | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | | | | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | Original | | S4330520Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | MAC | | Original | | S4330250Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | 1.0 | Original | | S4330220Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | SierraOriginals | | S6460220Z12ZZ | |
| Space Overlords | PC | | Original | | CD-EXC-OVERLORD | |
| Space Ofera Agga Ruter: Kyoufu no Uchuu Majo Space Ofera アッガ・ルター 恐怖の宇宙魔女 | PC | | Original | | | |
| Space Marisar スペースマリサー | PC | 1.00 | Original | | | |
| Space Marines: Der Stählerne Kaiser | PC | | All You Can Play: Adventure & Fantasy | | | |
| Space Marines (Disc 2) | PC | | Classic Line | | | |
| Space Marines (Disc 1) | PC | | Classic Line | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam スペース・ジャム | SS | 1.000 | Original | | T-8119G | |
| Space Jam スペースジャム | PSX | | Original | | SLPS 00697 | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Invaders: The Original Game スペースインベーダー | PC | | Original | | | |
| Space Invaders: The Original Game Space Invaders '95 | PC | | Original | | | |
| Space Invaders: Galaxy Beat スペースインベーダー ギャラクシービート | PSP | 1.02 | Original | | ULJM 05045 | |
| Space Invaders X | PC | 1.0.0 | Sourcenext Selection | | | |
| Space Invaders X スペース・インベーダーX | PSX | | Original | | SLPM 86419 | |
| Space Invaders Pocket スペースインベーダー ポケット | PSP | 1.04 | Original | | ULJM 05015 | |
| Space Invaders Extreme | PSP | 1.00 | Original | | ULUS-10346 | |
| Space Invaders Extreme | PSP | 1.00 | Original | | ULES-01078 | |
| Space Invaders Evolution | PSP | 1.02 | Original | | ULES-00348 | |
| Space Invaders Anniversary 스페이스 인베이더 애니버서리 | PS2 | 1.01 | Original | | SLKA 15025 | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 EUROPEAN | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Space Invaders | PC | 1.1 | Xplosiv | | XP-1867 EUROPEAN | |
| Space Invaders | PC | | Original | | 1000916.101.UK | |
| Space Invada!! Type Shinai to Tama ga Denai. SPACE INVA打!! / SPACE INVADERS!! タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Space in Motion: Future Trade | PC | 1.01 | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H | |
| Space Hulk: Vengeance of the Blood Angels | PC | | Original | | E348EDED | |
| Space Hulk | PS3 | 01.02 | Original | | BLKS 20514 | |
| Space Hulk | PS3 | 01.02 | Original | | BLES-02154 | |
| Space Hulk | PC | | Original | | E2105CCD | |
| Space Hack | PC | 1.02 | Original | | | |
| Space Engineers | PC | | Limited Edition | | | |
| Space Empires V Космическая Империя V | PC | 1.66 | Original | | | |
| Space Empires V | PC | 1.30 | Covermount | | | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Space Dynagon Kai スペース大納言(改 | PC | | Original | | MSCD-0026 | |
| Space Dudes | PC | | Original | | | |
| Space Dogs: Adventure to the Moon Белка и Стрелка. Лунные приключения | PC | 1.0.0 | Original | | | |
| Space Debris | PSX | | Original | | SCES-02433 | |
| Space Debris | PSX | | Original | | SCES-02431 | |
| Space Debris | PSX | | Original | | SCES-02430 | |
| Space Debris | PSX | | Original | | SCES-02290 | |
| Space Crusade | PC | | | | | |
| Space Colony | PC | | Original | | | |
| Space Colony (Disc 2) (Jugar) | PC | | Original | | | |
| Space Colony (Disc 1) (Instalación) | PC | | Original | | | |
| Space Colony (Install) | PC | | Green Pepper | | | |
| Space Colony (Play) | PC | | Green Pepper | | | |
| Space Colony | PC | | Original | | | |
| Space Clash: The Last Frontier | PC | | Sold Out Software | | | |
| Space Clash | PC | | Original | | M-25324-1999 | |
| Space Clash Space Clash: Das letzte Imperium | PC | | Original | | | |
| Space Chimps | PS2 | 1.03 | Original | | SLUS 21783 | |
| Space Chimps | WII | | Original | | RVL-RP9E-USA | |
| Space Chimps | XBOX360 | | Original | | BT-2004 Version: 1. | |
| Space Chimps | PS2 | 1.02 | Original | | SLES-55340 | |
| Space Chimps | XBOX360 | | Original | | BT-2004 | |
| Space Chimps | PS2 | 1.00 | Original | | SLES-55348 … | |
| Space Channel 5 Part 2 スペース・チャンネル5 パート2 | DC | 2.000 | Original | | HDR-0190 | |
| Space Channel 5 スペースチャンネル5 | PS2 | 1.00 | Original | | SLPM 65095 | |
| Space Camp | WII | | Original | | RVL-RIYE-USA | |
| Space Camp | WII | | Original | | RVL-RIYP-EUR | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Bucks: Spedition Galactica | PC | | Game-Pack 3 | | 80222 | |
| Space Bucks | PC | | Original | | | |
| Space Bucks | PC | | Original | | S4710520Z12ZZ | |
| Space Blaster Swarm | PC | | Original | | | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015-50 | |
| Space Adventure Cobra: The Shooting コブラ・ザ・シューティング | PSX | | Original | | SLPS 00312 | |
| Space Ace CD-ROM (PC and Compatibles) Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | 2.0 | | | SANSARL-01 | |
| Space Ace | PC | | Original | | | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | PC | 2.1 | All You Can Play: Adventure & Fantasy | | | |
| Soviet Strike | PSX | Rev 1 | Greatest Hits | | SLUS-00061 | |
| Soviet Strike ソビエト・ストライク | SS | 1.000 | Original | | T-10621G | |
| Soviet Strike ソビエトストライク | PSX | | Original | | SLPS 00735 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-18 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-50 | |
| South Park: The Stick of Truth | PC | | Original | | 689058-DVD | |
| South Park: The Stick of Truth South Park: Палка Истины | XBOX360 | | Classics | | US-2245 | |
| South Park: The Stick of Truth | PS3 | 01.00 | Original | | BLES-02002 … | |
| South Park: The Stick of Truth | XBOX360 | | Original | | US-2245 | |
| South Park: The Fractured But Whole (Disc 3) | PC | | Gold Edition | | UBP60802045-DISC3 | |
| South Park: The Fractured But Whole (Disc 2) | PC | | Gold Edition | | UBP60802045-DISC2 | |
| South Park: The Fractured But Whole (Disc 1) | PC | | Gold Edition | | UBP60802045-DISC1 | |
| South Park: Der Stab der Wahrheit | PS3 | 01.00 | Original | | BLES-02003 | |
| South Park: Der Stab der Wahrheit | XBOX360 | | Original | | US-2245 | |
| South Park: Chef's Luv Shack | DC | 1.000 | Original | | T-8105D-50 | |
| South Park: Chef's Luv Shack | PC | | Original | | CD194190.00-EUR | |
| South Park Rally | DC | 1.001 | Original | | T-8116N | |
| South Park | PC | | Original | | | |
| Souten no Shiroki Kami no Kura: Great Peak 蒼天の白き神の座 -GREAT PEAK- | PSX | | Original | | SCPS 10058 | |
| Soushun: Tsutaetai Koto 想瞬 ーつたえたいことー | PC | | Original | | | |
| Sousei Seiki Devadasy: Repeator Amara 創世聖紀デヴァダシー REPEATOR AMARA | PC | | PC Game Best Series | | | |
| Sousei no Aquarion 創聖のアクエリオン | PS2 | 1.01 | Original | | SLPS 25519 | |
| sourirE | PC | 1.00 | Original | | | |
| Sound Qube サウンド・キューブ | SS | 1.001 | Original | | T-4318G | |
| Sound Qube サウンド・キューブ | PSX | | Original | | SLPS 01309 | |
| Sound Qube サウンド・キューブ | PSX | | Best of the Best | | SLPS 02716 | |
| Sound Novel Tkool 2 サウンド・ノベル・ツクール2 | SS | 1.003 | Original | | T-2108G | |
| Sound Novel Machi (Disc 2) (10.13-10.15 Incl.) サウンドノベル 街 | SS | 1.001 | Original | | T-34001G | |
| Sound Eye Julian (Disc 4) サウンドアイ ジュリアン | PC | | Original | | FCG-015 | |