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![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]")
| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|---|---|---|---|---|---|---|
 | Sydney 2000 | DC | 1.000 | Original |  | T-36808N |  |
| Surf Rocket Racers | DC | 1.000 | Original | | T-40216N | |
 | The Suffering | PS2 | 1.02 | Original |   | SLES-51693 | |
| Stunt GP | PS2 | 1.00 | Original |     | SLES-50064 | |
| Street Fighter III: 3rd Strike | DC | 1.001 | Original | | T-1213N | |
| Street Fighter Alpha 3 | DC | 1.001 | Original | | T-1203N | |
| Steel Harbinger | PSX | Original | | SLES-00373 | | |
| StarLancer | DC | 1.002 | Original | | T-40209N | |
| Speed Devils | DC | 1.004 | Original | | T-17702N | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-1216N | |
| Sol-Feace | MCD | Bundled with Mega-CD (Sol-Feace / Cobra Command Bundle) | 4130 | | ||
| Sky Sports Football Quiz | PSX | Original | | SLES-03776 | | |
| Skies of Arcadia (Disc 2) | DC | 1.002 | Original | | 51052 | |
| Skies of Arcadia (Disc 1) | DC | 1.002 | Original | | 51052 | |
 | SingStar '80s | PS2 | 2.00 | Original | | SCES-53609 … | |
| Silent Scope | DC | 1.000 | Original | | T-9507N | |
 | Shougi Matsuri 将棋まつり | SS | 1.002 | Original |  | T-16502G | |
 | Shoot 'Em Up Vol. 1 | PC | 1.1 | Original | | AP-003 | |
| Shadow Man | DC | 1.010 | Original | | T-8106N | |
| The Settlers | PC | PC Best Buy Pocket | 900813 | | ||
 | The Settlers III (Disc 2) | PC | Revival | REV036 | | ||
| The Settlers III (Disc 1) | PC | Revival | REV036 | | ||
| Sento Monogatari Sono I 「占都物語」そのⅠ | SS | 1.000 | Original | | T-6801G | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| The Secret of Monkey Island | MCD | Original | | T-60035 | | |
| Samurai Shodown Anthology | PS2 | 1.01 | Original | | SLES-55292 | |