Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sea Adventures | PC | | Microforum | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7P-EUR | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| Sea Plane Adventures Sea Plane Adventures for FS2002/2004 | PC | | Original | | | |
| Sea Rescue | PC | | Nestlé Corn Flakes | | | |
| Sea War Sea War: Entscheidungsschlacht im Pazifik | PC | | Original | | SPI 023 | |
| Sea-Doo Hydro Cross | PSX | | Original | | SLUS-01149 | |
| Seal: Travelers of Destiny SEAL~運命の旅人~ | PC | | Original | | MKD-1390 | |
| Search & Rescue 3 | PC | | Original | | ASS256A181-0001-0001-02 | |
| Search and Rescue Air Rescue | PC | | Grabit | | GDL024 | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Seasons Greetings from Philips Media | CDI | | Original | | | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| Secre Demo Disk | FMT | | Hibaihin | | HME-921 | |
| Secre Fuumin no Omochabako セクレ・フーミンのおもちゃ箱 | 3DO | | Original | | FZ-SJ2651 | |
| Secre Volume 3: Fumie Hosokawa SECRE VOLUME ③ 「細川 ふみえ」 | FMT | | Original | | HME-191 | |
| Secre Volume 4: Hitomi Fujisaki SECRE VOLUME ④ 「藤崎 仁美」 | FMT | | Original | | HME-196 | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Volume 6: Reiko Kato SECRE VOLUME ⑥ 「かとう れいこ」 | FMT | | Original | | HME-205 | |
| Secre Volume 7: Reiko Chiba SECRE VOLUME ⑦ 「千葉 麗子」 | FMT | | Original | | HME-209 | |
| Secre Volume I: Naoko Iijima SECRE VOLUME ① 「飯島 直子」 | FMT | | Original | | HME-168 | |
| Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
| Secret Files 2: Puritas Cordis | WII | | | | RVL-RZFP-EUR | |
| Secret Files 2: Puritas Cordis | PC | | Original | | ECD900341D | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUP-EUR | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| Secret Mission | CDI | | Original | | 810 0272 | |
| Secret Mission | CDI | | Original | | 814 0133 | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island モンキー・アイランド | FMT | | Original | | HMD-155 | |
| The Secret of Monkey Island モンキー・アイランド ~ユーレイ海賊大騒動!~ | MCD | | Original | | T-60044 | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| The Secret of the Nautilus | PC | | Original | | JVEENCD1 | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| Secret of Video Architecture X68000画面表示仕様の秘密 | X68K | | Original | | | |
| Secret Safari シークレットサファリ | PC | | Original | | VIRL-8 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85P-EUR-B0 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| Secret Service CD 36 | PC | | | | | |
| Secret Service CD 37 | PC | | | | | |
| Secret Service CD 38 | PC | | | | | |
| Secret Service CD 39 | PC | | | | | |
| Secret Service CD 40 | PC | | | | | |
| Secret Service CD 43 | PC | | | | | |
| Secret Service CD 44 (Strona A) | PC | | | | | |
| Secret Service CD 44 (Strona B) | PC | | | | | |
| Secret Service CD 45 | PC | | | | | |
| Secret Service CD 47 (Strona A) | PC | | | | | |
| Secret Service CD 47 (Strona B) | PC | | | | | |
| Secret Service CD 48 (Strona B) | PC | | | | | |
| Secret Service CD 49 (Strona A) | PC | | | | | |
| Secret Service CD 49 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona A) | PC | | | | | |
| Secret Service CD 50 (Strona B) | PC | | | | | |
| Secret Service CD 51 (Strona B) | PC | | | | | |
| Secret Service CD 52 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona B) | PC | | | | | |
| Secret Service CD 53 (Strona A) | PC | | | | | |
| Secret Service CD 53 (Strona B) | PC | | | | | |
| Secret Service CD 60 | PC | | | | | |
| Secret Service CD 61 | PC | | | | | |
| Secret Service CD 64 | PC | | | | | |
| Secret Service CD 87 | PC | | | | | |
| Secret Service CD 88 | PC | | | | | |
| Secret Service CD 89 | PC | | | | | |
| Secret Service CD 90 | PC | | | | | |
| Secret Service CD 91 | PC | | | | | |
| Secret Weapons of the Luftwaffe | PC | | Collezione CD-Rom by C.T.O. | | | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy (Disc 1) | PC | | Original | | 32609.101.GM | |
| Secret Weapons over Normandy (Disc 2) | PC | | Original | | 32609.102.GM | |
| Secret Weapons over Normandy (Disc 3) | PC | | Original | | 32609.103.GM | |
| Secret Weapons over Normandy (Disc 4) (Spiel-CD) | PC | | Original | | 32609.104.GM | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| The Secret World (Disc 1) | PC | | Original | | EAX07709446D | |
| The Secret World (Disc 2) | PC | | Original | | EAX07709446D2 | |
| Les Secrets d'Alamut (Disc 1) | PC | | Original | | ALAFR1P | |
| Les Secrets d'Alamut (Disc 2) | PC | | Original | | ALAFR2P | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Dark: Der finstere Berg | PC | | Original | | | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy | PC | | Original | | CDR3015 | |
| Seek and Destroy Seek & Destroy | CD32 | | Original | | | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future 세가 GT 2002 + 젯 셋 라디오 퓨처 · 噴射小子 未來版 | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega Hard Historia セガハードヒストリーア | PC | | Book Bundle | | | |
| Sega Marine Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1606 | |
| Sega Mega Drive Classic Collection Volume 3 | PC | | Original | | SEGA-PC120 | |
| Sega Memorial Selection: Dear 80's Videogame Best 3 | PC | | Ultra 2000/Ultra Series | | MKW-183 | |
| Sega Net Mahjong MJ Arcade セガNET麻雀MJ Arcade | SRE | | Original | | DVR-5055D | |
| Sega Network Taisen Mahjong MJ5 セガネットワーク対戦麻雀MJ5 | SRE | | Original | | DVR-0027 | |
| Sega Network Taisen Mahjong MJ5 Evolution セガネットワーク対戦麻雀MJ5 EVOLUTION | SRE | | Original | | DVR-0071 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083D | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | PC Game Bundle | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Racing Classic | SRE | | RingWide | | DVR-0009A | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally 2: Sega Rally Championship (Install Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally 2: Sega Rally Championship (Play Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Original | | 670-9827 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Mihon-hin | | 670-10314 | |
| Sega Rally Revo セガラリー レヴォ | XBOX360 | | Original | | SE-2022 | |
| Sega Saturn Development Tool Kit | PC | | Original | | 610-5750 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Soccer Slam | XBOX | | Original | | IG-041 | |
| Sega Soccer Slam セガ サッカースラム | GC | | Original | | DL-DOL-GSSJ-JPN | |
| Sega Soccer Slam | XBOX | | Original | | SE-020 | |
| Sega Touring Car Championship 世嘉巡回车大赛 | PC | | Original | | | |
| Sega Touring Car Championship | PC | | Fair Game: Quality Value | | FG-1306 EUROPEAN | |
| Sega Worldwide Soccer PC | PC | | 3D Power Pack | | 500-0009-50 | |
| Sega Worldwide Soccer PC | PC | | Fair Game | | FG-1281 | |
| SegaSaturn: Graphic & Sound Tools for Macintosh | SS | | Original | | N16-1000 | |
| SegaSaturn: Movie Tools: Cinepak for Sega Saturn | SS | | Hybrid Version | | L17-1000 | |
| Sei Shirasagi Jogakuen Vol. 2: Tsukahara Shiho-hen 聖シラサギ女学園 Vol.2 塚原 シホ編 | PC | | Original | | SCR-1997-02 | |
| Sei Shirasagi Jogakuen Vol. 3: Sunada Misaki-hen 聖シラサギ女学園 Vol.3 砂田 ミサキ編 | PC | | Original | | SCR-1997-03 | |
| Le Seigneur des Anneaux: Le Retour du Roi | XBOX | | Original | | EA-062 | |
| Le Seigneur des Anneaux: Le Tiers Age | XBOX | | Original | | EA-095 | |
| Seijo Vampire 聖女ヴァンパイア | PC | | Original | | MMM-7881 | |
| Seikai Risshiden: Kimi wa Nihon no Leader ni Nareru ka! 政界立志伝~君は日本のリーダーになれるか!~ | PC | | | | MSDJ-99094 | |
| Seinarukana: The Spirit of Eternity Sword 2 聖なるかな ーThe Spirit of Eternity Sword 2ー | PC | | Special Package | | | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Original | | SLPS 01271 | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Taikenban Special Disc | | SLPM 80271 | |
| Seireiki Rayblade 聖霊機ライブレード | PSX | | Original | | SLPS 02652 | |
| Seishoujo Kantai Virgin Fleet 聖少女艦隊・バージン・フリート | PSX | | Original | | SLPM 86191 | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Sem' Samuraev (Disc 1) Семь Самураев | PC | | Original | | | |
| Sem' Samuraev (Disc 2) Семь Самураев | PC | | Original | | | |
| Sengoku Basara 2: Heroes: Double Pack (Sengoku Basara 2) 戦国BASARA2 | WII | | Original | | RVL-RBSJ-1-JPN | |
| Sengoku Basara 2: Heroes: Double Pack (Sengoku Basara 2: Heroes) 戦国BASARA2 英雄外伝 | WII | | Original | | RVL-RBSJ-0-JPN | |
| Sengoku Basara 3 戦国BASARA3 | WII | | Original | | RVL-SB3J-JPN-B0 | |
| Sengoku Basara 3: Utage 戦国BASARA3 宴 | WII | | Original | | RVL-S3HJ-JPN-B0 | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! 戦国美少女絵巻 空を斬る!! | PC | | Original | | TGL-98 0220 | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! Harukaze no Shou 戦国美少女絵巻 空を斬る!! ~春風の章~ | PC | | Original | | | |
| Sengoku Musou 3: Moushouden 戦国無双3 猛将伝 | WII | | Original | | RVL-S5QJ-JPN-E0 | |
| Sengoku Musou: Katana 戦国無双 KATANA | WII | | Original | | RVL-RS5J-JPN | |
| Sengoku-hime 2: Senran no Yo, Gunyuu Arashi no Gotoku 戦極姫2 ~戦乱の世、群雄嵐の如く~ | XBOX360 | | Original | | SY-2002 | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc 戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senkai Taisen: TV Animation Senkaiden Houshin Engi yori 仙界大戦 ~TVアニメーション仙界伝封神演義より~ | PSX | | Original | | SLPS 02736 | |
| Senkai Tsuuroku Seishi: TV Animation Senkaiden Houshin Engi yori 仙界通録正史 ~TVアニメーション仙界伝封神演義より~ | PSX | | Original | | SLPS 03176 | |
| Senkou no Ronde Duo 旋光の輪舞DUO | XBOX360 | | Limited Edition | | GR-2041 | |
| El Señor de los Anillos: El Retorno del Rey | XBOX | | Original | | EA-062 | |
| El Señor de los Anillos: La Tercera Edad | XBOX | | Original | | EA-095 | |
| Senran 戦乱 | PSX | | Original | | SLPS 00427 | |
| Senryaku Shidan: Tora! Tora! Tora! Rikusen-hen 戦略師団 トラ!トラ!トラ!陸戦編 | PSX | | PSone Books | | SLPS 91422 | |
| Senryaku Shougi 戦略将棋 | PSX | | Original | | SLPS 00142 | |
| Sensible Soccer | MCD | | Original | | T-93185-50 | |
| Sensible Soccer 2006 | XBOX | | Original | | CM-091 | |
| Sensible World of Soccer '96/'97 (Upgrade PC CD-ROM Disc) | PC | | Original | | | |
| Sentimental Graffiti センチメンタルグラフティ | PSX | | Original | | SLPS 03184 | |
| Sentimental Graffiti (Disc 1) センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01A | |
| Sentimental Graffiti (Disc 2) センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01B | |
| Sentimental Graffiti: Yakusoku センチメンタルグラフティ~約束~ | PSX | | Original | | SLPS 03183 | |
| Sentimental Journey センチメンタル・ジャーニー | PSX | | Original | | SLPS 01473 | |
| Sentinel Returns | PC | | Original | | | |
| Sento Monogatari: Sono I 占都物語 そのI | PSX | | Original | | SLPS 00124 | |
| Sento Monogatari: Sono I 「占都物語」 そのI | PC | | Original | | | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora 戦闘妖精雪風 ~妖精の舞う空~ | XBOX | | Original | | AQ-003 | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 1) (Installation CD-ROM) 戦闘妖精雪風~妖精の舞う空~ | PC | | Original | | SYYi-V1.00 | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 2) (Game CD-ROM) 戦闘妖精雪風~妖精の舞う空~ | PC | | Original | | SYYg-V1.00 | |
| Septentrion: Out of the Blue セプテントリオン ~Out of the Blue~ | PSX | | Original | | SLPS 01940 | |
| Septentrion: Out of the Blue セプテントリオン ~Out of the Blue~ | PSX | | Major Wave | | SLPM 86612 | |
| Septerra Core: Legacy of the Creator | PC | | Covermount | | ADB 0103 | |
| Sequence Palladium Mania Kit: Desktop Accessory シークエンス・パラディウム マニアキット デスクトップアクセサリ | PC | | Original | | WIC-6346 | |
| Sequence Palladium Premium Digital Novel | PC | | PC Game Bundle | | KGD-06021 | |
| Seraphim: Saigo no Tenshi セラフィム 最後の天使 | PC | | Original | | SCR-003 | |
| Serious Sam | XBOX | | Original | | TT-004 | |
| Serious Sam | XBOX | | Original | | TT-004 | |
| Serious Sam 3: BFE | PC | | Original | | MTC000692-D | |
| The Serious Sam Collection | XBOX360 | | Original | | MK-2010 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| Serious Sam HD | XBOX360 | | Promo | | MK-2004 | |
| Serious Sam HD: The First Encounter | PC | | Original | | | |
| Serious Sam HD: The Second Encounter Serious Sam HD: Второе Пришествие | PC | | Original | | | |
| Serious Sam II | PC | | Sold Out Software | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam: Next Encounter | GC | | Original | | DL-DOL-G3BP-EUR | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | | Rerelease | | | |
| Serp i Molot Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 1) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 2) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 3) Серп и Молот | PC | | 1C: Igroteka | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Sesame Street Kazu Asobi: A Visit to Sesame Street: Numbers セサミストリート かずあそび | CDI | | Original | | PCIM-00013 | |
| Sesame Street Moji Asobi: A Visit to Sesame Street: Letters セサミストリート もじあそび | CDI | | Original | | PCIM-00012 | |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Original | | RVL-SS4U-AUS-B0 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Original | | RVL-SS3U-AUS-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original | | SLES-02510 | |
| Sesame Street: Elmo's Musical Monsterpiece: The Videogame | WII | | Original | | RVL-SSSE-USA-B0 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: Let's Make a Word! | PC | | | | 7418 | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Numbers セサミ・ストリート ~ナンバーズ~ | 3DO | | Original | | FZ-SJ1664 | |
| Sesame Street: Numbers Улица Сезам: Учись считать | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Preschool Улица Сезам: Элмо готовит в школу | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Sesame Street: Ready, Set, Grover! with Elmo: The Videogame | WII | | Original | | RVL-SESE-USA-B0 | |
| Sesamstrasse: Auf die Krümel, fertig, los! | PC | | Rerelease | | GSL854AG-CD | |
| Session Power Up Kit for DrumMania 2nd Mix / PercussionFreaks 2nd Mix | KS573 | | Original | | 912 *Z A01 | |
| Sethi und das Geheimnis der Neandertaler | PC | | Rerelease | | | |
| Sethi: Abenteuer im Mittelalter National Geographic: Sethi: Abenteuer im Mittelalter | PC | | Original | | | |
| The Settlers II | PC | | Demo | | | |
| The Settlers II: 10-lecie The Settlers II: 10th Anniversary | PC | | eXtra Klasyka Next | | | |
| The Settlers II: 10th Anniversary Die Siedler II: Die nächste Generation | PC | | Gold Edition (Software Pyramide) | | 300025385 | |
| The Settlers II: 10th Anniversary: Vikings Die Siedler II: Die nächste Generation: Wikinger | PC | | Gold Edition (Software Pyramide) | | 300025389 | |
| Settlers II, The: Veni, Vidi, Vici | PC | | Budget | | MMICDR 5803 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers III: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers IV | PC | | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Original | | | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Gold Edition | | | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Złota Edycja | PC | | Nowa eXtra Klasyka | | | |
| The Settlers | PC | | Rerelease | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | PC Best Buy Pocket | | 900813 | |
| The Settlers: Dziedzictwo Królów The Settlers: Heritage of Kings | PC | | eXtra Klasyka Next | | | |
| The Settlers: Heritage of Kings: Gold Edition (Legends Expansion Disc) | PC | | That's Hot! | | 5004531 | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Original | | 5004220 | |
| The Settlers: Heritage of Kings: Gold Edition | PC | | Covermount | | | |
| The Settlers: Rascvet Imperii The Settlers: Расцвет империи | PC | | Original | | | |
| The Settlers: Rise of an Empire | PC | | Software Pyramide | | 300030091 | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Original | | | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Cool Games | | | |
| Seven Kingdoms: Ancient Adversaries | PC | | | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
| Seven Years War 2 + Joseonui Bangyeok 임진록 2 + 조선의 반격 | PC | | Hapbon | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 1) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 2) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 3) 第七封印:魔神甦醒 | PC | | Original | | | |
| Sewer Shark | MCD | | Original | | T-93015-50 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Original | | T-6201 | |
| Sex Sensou: Aiaru H wa Kinshi desu! H-na Hiyakeato Patch SEX戦争~愛あるHは禁止ですっ!~Hな日焼け跡パッチ | PC | | Original | | | |
| Sexy Bytes: Lacquer & Leather | PHOTO-CD | | Original | | | |
| Sexy Bytes: Outside Dreams | PHOTO-CD | | Original | | | |
| Sexy Bytes: Rolling Mountains | PHOTO-CD | | Original | | | |
| Sexy Bytes: Studio Girls 1 | PHOTO-CD | | Original | | | |
| Sexy PK: World Cup-ban セクシー・ピーケー ワールドカップ版 | MAC | | Original | | MMC-4065 | |
| Sfera Сфера | PC | | | | | |
| Sfera II: Arena Сфера II: Арена | PC | | Original | | | |
| Sfera: Materik Vlasti Сфера: Материк Власти | PC | | 1C: Kollekciya igrushek | | | |
| Sfera: Prokljatie Giperiona Сфера: Проклятие Гипериона | PC | | 1C: Kollekciya igrushek | | | |
| Sfida nella Piramide! | PC | | Evviva! Software | | | |
| Shade: Wrath of Angels (Press Disc) | PC | | Press Kit | | | |
| Les Shadoks: Le Jeu: La Promenade | PC | | Original | | PCMCSHAD97FCD1 | |
| Shadow Company: Left for Dead | PC | | Back to Games | | | |
| Shadow Company: Left for Dead (Digital Press Kit) | PC | | Press Kit | | 5051895 | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Shadow Force: Razor Unit | PC | | Special Forces Pack | | SFRU-0414 | |
| Shadow Hearts: Special Disc SHADOW HEARTS スペシャルディスク | PC | | Hibaihin | | | |
| Shadow Man | PC | | Wanted Games | | CD194141.00-EUR | |
| Shadow Man: Rette deine Seele | PC | | Original | | CD194141.03-GER | |
| Shadow Master | PC | | Dice | | DCG 005141, DMM 005424 | |
| Shadow of Memories | XBOX | | Original | | KN-014 | |
| Shadow Ops: Red Mercury | PC | | Original | | 1015571 | |
| Shadow Ops: Red Mercury | XBOX | | Original | | IG-065 | |
| Shadow Ops: Red Mercury | PC | | Original | | 1019185 | |
| Shadow Ops: Red Mercury | XBOX | | Demo | | IG-037 | |
| Shadow Ops: Red Mercury | XBOX | | Original | | IG-037 | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadow Vault Bonus CD Extra 1/2008 | PC | | | | | |
| Shadow Vault: Demos and Materials | PC | | Original | | | |
| Shadow Warrior | PC | | Original | | MTC000875-D | |
| Shadow Warrior: Digital Press Kit | PC | | Press Kit | | | |
| Shadow Wolf Mysteries: Curse of the Full Moon / Bane of the Family | PC | | | | 33425010US | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| Shadowgrounds (Disc 1) (Installation) | PC | | Original | | Art.-Nr. 9702270 | |
| Shadowgrounds (Disc 2) (Spiel) | PC | | Original | | Art.-Nr. 9702270 | |
| Shadowgrounds | PC | | Linux (LGP) | | | |
| Shadowgrounds Survivor | PC | | Linux (LGP) | | | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shakedown: Hawaii | WII | | Original | | RVL-SEVP-EUR-B0 | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shane Warne Cricket | PSX | | Original | | SLES-01576 | |
| Shanghai 上海 | WII | | Original | | RVL-RS8J-JPN | |
| Shanghai Dragon | PC | | Covermount | | | |
| Shanghai: Banri no Choujou 上海 万里の長城 | PSX | | Mouse Set Tsuki Gentei Box | | SCPS 10005 | |
| Shanghai: Banri no Choujou 上海 ~万里の長城~ | PC-FX | | Original | | FXNHE507 | |
| Shanghai: Banri no Choujou: The Great Wall 上海 ~万里の長城~ | 3DO | | Original | | FZ-SJ1660 | |
| Shanghai: Great Moments 上海 グレートモーメンツ | PSX | | Original | | SLPS 00266 | |
| Shanghai: True Valor | PSX | | Original | | SLES-01618 | |
| Shangrlia 2 シャングリラ2 | FMT | | Original | | HME-220 | |
| Shaolin Shiba Tongren 少林十八銅人 | PC | | Original | | | |
| Shape Boxing 2: Wii de Enjoy Diet! シェイプボクシング2 Wiiでエンジョイダイエット! | WII | | Original | | RVL-SHIJ-JPN-B0 | |
| Shape Boxing: Wii de Enjoy Diet! シェイプボクシング Wiiでエンジョイダイエット! | WII | | Original | | RVL-REKJ-JPN-1 | |
| Shape Shifter | PCE | | Original | | TGXCD1021 | |
| Shape Shifter | PC | | Original | | | |
| Shareware CD Compilation n.40: Doom 1800 Niveaux | PC | | | | 1634 | |
| Shareware Games: The Best of 1996: Luglio/Agosto 1996 | PC | | | | | |
| Shareware Gold: PC Software | PC | | Original | | SGCD-01 | |
| Shareware-Hits zum Superpreis: Top 100 Spiele | PC | | Original | | | |
| Shari Lewis Lamb Chop's Play-Along! Action Songs | CDI | | Original | | 310690289-2 | |
| Sharin no Kuni, Himawari no Shoujo 車輪の国、向日葵の少女 | XBOX360 | | Limited Edition | | FV-2017 | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| Sharuui Takoron しゃるうぃ~☆たころん | WII | | Original | | RVL-RTKJ-JPN | |
| Shattered Horizon | PC | | Premium Edition | | | |
| Shattered Steel | PC | | Interactive Preview | | CD-ICD-308-0 | |
| Shattered Union | XBOX | | Original | | TT-131 | |
| Shattered Union | XBOX | | Original | | TT-131 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Skateboarding | WII | | Original | | RVL-SHNE-USA-B0 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Snowboarding | XBOX360 | | Promo | | US-2078 | |
| Shaun White Snowboarding | XBOX360 | | Original | | US-2078 | |
| Shaun White Snowboarding | XBOX360 | | Target Limited Edition | | US-2078 | |
| Shaun White Snowboarding: Road Trip | WII | | Beta | | | |
| Shaun White Snowboarding: World Stage | WII | | Original | | RVL-R6NE-USA-B0 | |
| Shaun White Snowboarding: World Stage | WII | | Original | | RVL-R6NP-UKV-B0 | |
| Shawn Johnson Gymnastics | WII | | Original | | RVL-SJVE-USA-B0 | |
| Sheep | PC | | Megapak 10 | | EI-1420 GERMAN | |
| Sheep, Dog 'n' Wolf: Interactive Demo | PSX | | Demo | | SLED-03631 | |
| ShellShock 2: Blood Trails | PC | | Original | | MSH02VMB01 | |
| Shelly Club: De Grote Dierenparade | PC | | Original | | | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Original | | MTC000653-D | |
| Sherlock Holmes contro Jack lo Squartatore | PC | | Covermount | | | |
| Sherlock Holmes e il Re dei Ladri | PC | | FX Interactive (Rerelease) | | IT v.1.0 P - DVD | |
| Sherlock Holmes Trilogy | PC | | Original | | | |
| Sherlock Holmes Versus Jack the Ripper | XBOX360 | | Original | | FE-2003 | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | XBOX360 | | Original | | JW-2003 | |
| Sherlock Holmes: Consulting Detective | MCD | | Original | | 4650 | |
| Sherlock Holmes: Consulting Detective: Vol. I | VIS | | Original | | 25-6183 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Rerelease | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 2) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II | VIS | | Original | | 25-6184 | |
| Sherlock Holmes: Consulting Detective: Vol. II | PCE | | Original | | TGXCD1039 | |
| Sherlock Holmes: Crimes & Punishments | XBOX360 | | Original | | FE-2015 | |
| Sherlock Holmes: Das Geheimnis des persischen Teppichs | PC | | Original | | Artikel Nummer 31173 | |
| Sherlock Holmes: Das Geheimnis des silbernen Ohrrings | PC | | Special Edition | | | |
| Sherlock Holmes: The Awakened | PC | | Original | | | |
| Sherlock Holmes: The Case of the Silver Earring (Disc 1) | PC | | Reload / White Label | | 1480A1 | |
| Sherlock Holmes: The Case of the Silver Earring (Disc 2) | PC | | Reload / White Label | | 1480A2 | |
| Sherlok Xolms protiv Arsena Lyupena Шерлок Холмс против Арсена Люпена | PC | | Original | | | |
| Sherlok Xolms: Luchshie dela Шерлок Холмс: Лучшие дела | PC | | Original | | | |
| Sherlok Xolms: Pyat' egipetskix statue'tok Шерлок Холмс: Пять египетских статуэток | PC | | 1C: Igroteka | | | |
| Sherlok Xolms: Vozvrashhenie Moriarti Шерлок Холмс: Возвращение Мориарти | PC | | Original | | | |
| Sherman M4 | PC | | Action Sixteen | | | |
| Shiawase Usagi II: Toraware Usagi Sailor Z しあわせうさぎⅡ とらわれうさぎセーラーZ | PCE | | Unlicensed | | | |
| Shiawase Usagi: Nureta Bishoujo: Hajimete Nanoni... しあわせうさぎ ~濡れた美少女‐初めてなのに…~ | PCE | | Unlicensed | | | |
| Shichida-shiki Unou de Asobenture Vol. 1: Kotoba ABC: 0-2-sai Muke 七田式 右脳でアソベンチャー① 【ことばABC 0歳~2歳向け】 | PSX | | Original | | SLPM 86527 | |
| Shichida-shiki Unou de Asobenture Vol. 2: Katachi 123: 0-2-sai Muke 七田式 右脳でアソベンチャー② 【かたち123 0歳~2歳向け】 | PSX | | Original | | SLPM 86528 | |
| Shichida-shiki Unou de Asobenture Vol. 3: Kotoba ABC: 2-4sai Muke 七田式 右脳で遊勉チャー③ 【ことばABC 2歳~4歳向け】 | PSX | | Original | | SLPM 86529 | |
| Shichida-shiki Unou de Asobenture Vol. 4: Katachi 123: 2-4-sai Muke 七田式 右脳でアソベンチャー④ 【かたち123 2歳~4歳向け】 | PSX | | Original | | SLPM 86530 | |
| Shichida-shiki Unou de Asobenture Vol. 5: Kotoba ABC: 4-6-sai Muke 七田式 右脳でアソベンチャー⑤ 【ことばABC 4歳~6歳向け】 | PSX | | Original | | SLPM 86531 | |
| Shichida-shiki Unou de Asobenture Vol. 6: Katachi 123: 4-6-sai Muke 七田式 右脳でアソベンチャー⑥ 【かたち123 4歳~6歳向け】 | PSX | | Original | | SLPM 86532 | |
| Shichisei Toushin Guyferd: Crown Kaimetsu Sakusen 七星闘神ガイファード ~クラウン壊滅作戦~ | PSX | | Original | | SLPS 01619 | |
| Shichuu Suimei Pitagraph 四柱推命 ~PITAGRAPH~ | PSX | | Original | | SLPS 00082 | |
| Shiei No Sona-nyl Refrain: What a Beautiful Memories 紫影のソナーニル Refrain -What a beautiful memories- | XBOX360 | | Original | | T4-2001 | |
| Shijou Saikyou no Video Bible: The Greatest Video Bible in the World 史上最強のビデオバイブル | FMT | | Original | | HMA-251 | |
| Shikakui Atama o Maruku Suru. Wii シカクいアタマをマルくする。 Wii | WII | | Original | | RVL-R4MJ-JPN | |
| Shiken ni Deru!? Haruno-chan 試験に出る!?はるのちゃん | PC | | Original | | MAY-20112 | |
| Shiki o Irodoru: Nihon no Shouka: Aki 四季を彩る 日本の唱歌 秋 | FMT | | Original | | HMC-103 | |
| Shiki o Irodoru: Nihon no Shouka: Fuyu 四季を彩る 日本の唱歌 冬 | FMT | | Original | | HMC-104 | |
| Shiki o Irodoru: Nihon no Shouka: Haru 四季を彩る 日本の唱歌 春 | FMT | | Original | | HMC-101 | |
| Shiki o Irodoru: Nihon no Shouka: Natsu 四季を彩る 日本の唱歌 夏 | FMT | | Original | | HMC-102 | |
| Shiki Oriori no Bass Tsuri 四季おりおりのバス釣り | PSX | | Original | | SLPS 02810 | |
| Shikigami no Shiro Evolution (Tokuten Data CD-ROM: Complete) 式神の城 EVOLUTION | PC | | Kurenai | | Q68-00001 KI001E01 | |
| Shikigami no Shiro EX 式神の城EX | PC | | Original | | MQD-3790 | |
| Shikigami no Shiro II 式神の城Ⅱ | XBOX | | Original | | KI-002 | |
| Shikigami no Shiro III 式神の城Ⅲ | XBOX360 | | Original | | AW-2002 | |
| Shikigami no Shiro III 式神の城Ⅲ | WII | | Original | | RVL-RS4J-JPN | |
| Shikigami No Shiro: Game Illustrations Art Book | PC | | Bundled with Book | | | |
| Shimada Youko: Quatre 島田陽・子カトル | PHOTO-CD | | Original | | FZ-JJ1YP0501 | |
| Shimano Extreme Fishing | WII | | Original | | RVL-R39P-EUR-B0 | |
| Shimano Xtreme Fishing | WII | | Original | | RVL-R39E-USA-B0 | |
| Shin Chan: Las Nuevas Aventuras para Wii! | WII | | Original | | RVL-RC4S-ESP | |
| Shin Chuuka Taisen: Michael to Meimei no Bouken 新・中華大仙 ~マイケルとメイメイの冒険~ | WII | | Original | | RVL-RTDJ-JPN | |
| Shin Jidaigeki Action: Rasetsu no Ken 新時代劇アクション ~羅刹の剣~ | PSX | | Original | | SLPM 86177 | |
| Shin Masou Kishin: Panzer Warfare 真・魔装機神 -PANZER WARFARE- | PSX | | Original | | SLPS 02319 | |
| Shin Master of Monsters Final 真・マスターオブモンスターズ Final | PC | | SystemSoft Selection 2000 | | SSA0028 | |
| A Shin Megami Tensei: Devil Children: Kuro no Shoka no Sho 真・女神転生デビルチルドレン 黒の書・赤の書 | PSX | | Original | | SLPM 87040 | |
| Shin Onryou Senki 真怨霊戦記 | PCE | | Original | | FCCD5003 | |
| Shin Onryou Senki (Disc 1) 真怨霊戦記 | PC | | Original | | | |
| Shin Onryou Senki (Disc 2) 真怨霊戦記 | PC | | Original | | | |
| Shin Samurai Spirits: Haoumaru Jigokuhen 真サムライ・スピリッツ ~覇王丸地獄変~ | PC | | Ultra 2000/Ultra Series | | MKW-266 | |
| Shin Sangoku Musou 4: Empires 真・三國無雙4 Empires | XBOX360 | | Original | | KO-2003 | |
| Shin Sangoku Musou 5: Empires 真・三國無雙5 Empires | XBOX360 | | Original | | KO-2023 | |
| Shin Sangoku Musou 5: Empires 真・三國無双5 Empires | XBOX360 | | Original | | KO-2023 | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc A) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc B) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc C) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc D) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend Tokubetsu-hen 新世紀エヴァンゲリオン 鋼鉄のガールフレンド 特別編 | PC | | Original | | | |
| Shin Senki Van-Gale: The War of Neo-Century 新戦記ヴァンゲイル | PSX | | Original | | SLPS 00873 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWB-7007 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | Original | | EMW-4034 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWD-711 | |
| Shine Memories シャインメモリーズ | PC | | Original | | | |
| Shingata Kururin Pa! 新型くるりんPA! | PSX | | Original | | SLPS 00414 | |
| Shining Force CD | MCD | | Original | | 4656-50 | |
| Shining Hearts: Kaizoku Hihou Fan Disk シャイニング・ハーツ 海賊秘法ファンディスク | PC | | Pre-Order Bonus | | | |
| Shining Soul II + Shining Force Assets Shining Soul 2 + Shining Force Assets | PC | | Press Kit | | | |
| Shinjuwan Kougeki Taiheiyou Sensen 3: For Combat Flight Simulator 真珠湾攻撃 太平洋戦線3 For Combat Flight Simulator | PC | | Original | | | |
| Shinma Kourin 神魔降臨 | PC | | Original | | ICCD-005 | |
| Shinobi no Roku 忍ノ六 | PSX | | Original | | SLPS 02877 | |
| Shinpi no Sekai: El Hazard 神秘の世界 エルハザード | PHOTO-CD | | Original | | PIRW-1010 | |
| The Shinri Game 10 ザ・心理ゲーム10 | PSX | | Original | | SLPS 03174 | |
| The Shinri Game 5 ザ・心理ゲーム5 | PSX | | Original | | SLPS 02518 | |
| The Shinri Game 6 ザ・心理ゲーム6 | PSX | | Original | | SLPS 02668 | |
| The Shinri Game 9 ザ・心理ゲーム9 | PSX | | Original | | SLPS 03109 | |
| The Shinri Game ザ・心理ゲーム | PSX | | Original, Renkaban | | SLPS 00169 … | |
| Shinseiki Kouboushi: Dead Force 新世紀興亡史 デッド・フォース | FMT | | Original | | | |
| Shinsetsu Shiawase Usagi 2: Kairaku e no Invitation 真説しあわせうさぎ2 ~快楽へのインビテーション~ | PCE | | Unlicensed | | | |
| Shinsetsu Shiawase Usagi f: Yuujou yorimo Aiyoku 真説しあわせうさぎf ~友情より愛欲~ | PCE | | Unlicensed | | | |
| Shinsou Kaiten!! Wan Wan Umi Monogatari: Sanyo Pachinko Paradise DX 新装開店!! わんわん海物語 ~三洋パチンコパラダイス DX~ | PSX | | Original | | SLPS 03312 | |
| Ship Simulator 2008: The Official Add-On: New Horizons | PC | | Original | | | |
| Shiren the Wanderer | WII | | Beta | | | |
| Shiren the Wanderer | WII | | Original | | RVL-RFSE-USA-B0 | |
| Shirotsumesouwa: Episode of the Clovers (Disc 1) 白詰草話 -Episode of the Clovers- | PC | | Shokai Genteiban | | | |
| Shirotsumesouwa: Episode of the Clovers (Disc 2) 白詰草話 -Episode of the Clovers- | PC | | Shokai Genteiban | | | |
| Shirotsumesouwa: Episode of the Clovers: Extra Compact Disc 『白詰草話 -Episode of the Clovers-』エクストラCD | PC | | Original | | | |
| Shisenfuu Gekikara Mahjong 四川風激辛麻雀 | PSX | | Original | | SLPS 01648 | |
| Shitai o Arau 肢体を洗う | PC | | Demo | | SLKC027 | |
| Shitsuren しつれん | PC | | Original | | | |
| Shiver Bundle | PC | | Software Pyramide | | | |
| Shivers | PC | | Original | | | |
| Shivers | PC | | SierraOriginals | | S6480120Z12ZZ | |
| Shivers | PC | | Original | | S4430210Z12ZZ | |
| Shivers | PC | | Demo | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |