Region | Title | System | Version | Edition | Languages | Serial | Status |
| Schleichfahrt | PC | | Hemming | | | |
| Schleichfahrt | PC | | Original | | | |
| Schleichfahrt | PC | | | | | |
| Schmidt Interaktivspaß: Brettspiele | PC | | Original | | S0022616 | |
| Schmidt Interaktivspass: Kartenspiele | PC | 1.0.0.0 | Original | | S0022612 | |
| Schmidt Interaktivspaß: Mahjong | PC | | Original | | S0023095 | |
| Schmidt Interaktivspaß: Skat | PC | | Original | | S0022595 | |
| Schmidt Interaktivspaß: Spiele für Kids | PC | | Original | | S0022620 | |
| Scholastic's The Magic School Bus Discovers Flight: Activity Center | PC | 1.0.0.2 | Original | | 0201 Part No. X06-16068 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus: Jungle no Fushigi マジック スクール バス ジャングルのふしぎ | PC | | Original | | PRIR-01005 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Die Schöne und das Tier | CDI | | Original | | 813 0040 | |
| Die Schönsten Hotels der Welt | PHOTO-CD | | Original | | 813 0060 | |
| School Love! Koi to Kibou no Metronome すくぅ~る・らぶっ! ~恋と希望のメトロノーム~ | PS2 | 1.01 | Original | | SLPM 66641 | |
| School Rumble Nigakki: Kyoufu no Natsu Gasshuku! Youkan ni Yuurei Arawaru!? Otakara o Megutte Makkou Shoubu!!! no Maki スクールランブル二学期 恐怖の(?)夏合宿! 洋館に幽霊現る!? お宝を巡って真っ向勝負!!!の巻 | PS2 | 1.00 | Best Collection | | SLPS 25795 | |
| School Rumble: Neru Musume wa Sodatsu. スクール・ランブル ~ねる娘は育つ。~ | PS2 | 1.01 | DX Pack | | SLPS 25539 | |
| School Rumble: Neru Musume wa Sodatsu.: DTA Daisuki Tenma Accessory スクールランブル ねる娘は育つ。 DTA<大好き 天満アクセサリー> | PC | | DX Pack | | MII-012 | |
| School Tycoon | PC | | Scholastic | | P/N: CDR 21661-1R | |
| School Tycoon | PC | | Original | | | |
| School Wars: Sotsugyou Sensen スクール・ウォーズ~卒業戦線~ | PSP | 1.02 | Goukaban | | ROSE 00027 … | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Math Rock | PC | | Smart Saver | | SHR744AE-CD | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolmates: The Mystery of the Magical Bracelet | PC | | Original | | | |
| Schrei-Ten SCHREI・TEN シュライテン | PC | | Shokai Genteiban | | PISCKISS-01 | |
| Schrödinger no Neko: Die Katze von Schrödinger シュレディンガーの猫 | PSX | | Original | | SLPS 00780 | |
| Les Schtroumpfs: Le Téléportaschtroumpf | CDI | | Original | | SCHTRFR4011 | |
| Les Schtroumpfs: Le Téléportaschtroumpf | PC | | Original | | SCHTRFR5011 | |
| Der Schuh des Manitu Der Schuh des Manitu: Das Computerspiel zum Film | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Platinum Edition | PC | | Original | | | |
| Das Schwarze Auge: Satinavs Ketten | PC | | Limitierte Erstauflage | | ECD008798M ECD008799M ECD008907K ECD900830D 23032012-00 | |
| Das Schwarze Auge: Schatten über Riva | PC | | Gold Games 2 (CD 4) | | SPI 046 | |
| Das Schwarze Auge: Schatten über Riva | PC | | All You Can Play: Adventure & Fantasy | | | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | TopWare | | SPI 031 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | TopWare | | SPI 031 | |
| Schwarzschild EX: Tessa no Seigun シュヴァルツシルトEX ~鉄鎖の星群~ | PC-98 | | MS-DOS-ban | | 9214-55HM10 | |
| Schwarzschild GX: Sabita Sousei シュヴァルツシルトGX ~錆びた蒼星~ | PC-98 | | Original | | 9531-77-01 | |
| Schwarzschild GXR: Toki no Tsukaibito シュヴァルツシルトGXR 時現の遣人 | PC | | Original | | ID NO.9674-68-01 | |
| Schwarzschild IV: The Cradle End シュヴァルツシルトⅣ -THE CRADLE END- | FMT | | Original | | HME-223 | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| The Sci-Fi Collection | PC | | Original | | | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| Science & Nature: Elements Science 1: Elements | ARCH | 1.00 | Original | | | |
| Science & Nature: Materials Science Series II: Materials | ARCH | 1.00 | Original | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Science Is Elementary 1 | PSX | | Original | | LSP-990161 … | |
| Science Is Elementary 2 | PSX | | Original | | LSP-990162 … | |
| Science Is Elementary 3 | PSX | | Original | | LSP-990163 … | |
| Science: Electricity and Magnetism: Secondary Edition Science 3: Electricity and Magnetism | ARCH | 1.0 | Original | | | |
| Scissors 'n' Stones | PC | | Original | | | |
| Scooby Doo: Strachy na Lachy | PC | | | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | PC Fun Club | | PFC028/D | |
| Scooby-Doo et la Cybertraque | PSX | | Original | | SLES-03733 | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093083(UK) | |
| Scooby-Doo! and the Spooky Swamp | PS2 | 1.01 | Original | | SLES-55609 | |
| Scooby-Doo! and the Spooky Swamp | WII | | Original | | RVL-SJ2E-USA-B0 | |
| Scooby-Doo! and the Spooky Swamp | PS2 | 1.01 | Original | | SLUS 21928 | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | | GSP | | 1063A | |
| Scooby-Doo! First Frights | PS2 | 1.00 | Original | | SLUS-21900 | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Fluch der Folianten | GC | | Original | | DL-DOL-GC3D-NOE | |
| Scooby-Doo! Jinx at the Sphinx | PC | | GSP | | 1065A | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.0 | | | SCA844AB | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Scooby-Doo! La Nuit des 100 Frissons | GC | | Original | | DL-DOL-GIHF-FRA | |
| Scooby-Doo! La Nuit des 100 Frissons | PS2 | 1.00 | Original | | SLES-51018 | |
| Scooby-Doo! Le Livre des Ténèbres | GC | | Original | | DL-DOL-GC3F-FRA | |
| Scooby-Doo! Le Mystere du Parc Fantome | PC | | Original | | | |
| Scooby-Doo! Les Civilisations Perdues | VFLASH | | Original | | 093085(FR) | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3P-UKV | |
| Scooby-Doo! Mystery Mayhem | PS2 | 1.00 | Original | | SLUS-20701 | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Nacht der 100 Schrecken | GC | | Original | | DL-DOL-GIHD-NOE | |
| Scooby-Doo! Nacht der 100 Schrecken | PS2 | 1.00 | Original | | SLES-51019 | |
| Scooby-Doo! Night of 100 Frights | XBOX | | Original | | TQ-031 | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 0.00 | Beta | | | |
| Scooby-Doo! Night of 100 Frights | GC | Rev 1 | Original | | DL-DOL-GIHE-USA | |
| Scooby-Doo! Phantom of the Knight | PC | | SoftKey | | SPK854BB-CD | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooby-Doo! Phantom of the Knight | PC | | GSP | | 1064A | |
| Scooby-Doo! Pierwsze Strachy | PC | | Demo | | | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0 | Original | | SGW844AB-CD | |
| Scooby-Doo! Showdown in Ghost Town | PC | | GSP | | 1066A | |
| Scooby-Doo! Who's Watching Who? Scooby-Doo! Chi sta guardando chi? / Scooby-Doo! ¿Quién está mirando a quién? | PSP | 1.00 | Original | | ULES-00573 | |
| Scooby-Doo! Who's Watching Who? | PSP | 1.01 | Original | | ULUS-10168 | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Score International Baja 1000: The Official Game | PC | | Original | | 35619./101.US | |
| Score International Baja 1000: The Official Game | WII | | Original | | RVL-RJCE-USA | |
| Score International Baja 1000: The Official Game | PS2 | 1.00 | Original | | SLUS 21850 | |
| Score International Baja 1000: World Championship Off Road Racing | WII | | Original | | RVL-RJCP-EUR-B0 | |
| Score International Baja 1000: World Championship Off Road Racing | PS3 | 01.00 | Original | | BLES-00421 | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.00 | Demo | | SLUS 29036 | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.03 | Original | | SLUS-20424 | |
| Scotland Yard | PC | | Original | | | |
| Scotland Yard | PC | | Original | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| The Scottish Open: Virtual Golf | PC | | Euro Power Pack | | | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Interactive | WII | | Original | | RVL-RVHP-EUR-B0 | |
| Scrabble Interactive: 2003 Edition | PC | | Original | | | |
| Scrabble Interactive: 2003 Edition | PC | | Focus Essential | | ESS493 | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scratches | PC | | Original | | | |
| Scratches: Dans l'Antre de la Peur | PC | 0.92 Build 109 | Original | | 7816 | |
| Scratches: Director's Cut (Disc 1) | PC | | Original | | | |
| Scratches: Director's Cut (Disc 2) | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Scratches: Graffi Mortali | PC | | Original | | | |
| Screamball: The Ultimate Pinball Experience | PC | | Original | | | |
| Screaming Skies | PC | | Tewi | | Bestell-Nr. 27669 | |
| Screen Fighter Screen Saver スクリーンファイター スクリーンセーバー | PC | | Original | | SRC-00001 | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| The Scroll | PC | | | | | |
| The Scroll Daughter of Serpents | PC | | Original | | | |
| Scubeginners: I Misteri di Dive Island | PC | 1.1 | Original | | | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| Scudetto 2 | PC | 1.48 | CD-ROM Classic Collection 3 | | | |
| Scudetto 2006: Championship Manager | PSP | 1.00 | Original | | ULES-00332 | |
| Scudetto 4: Championship Manager: Stagione 2002-2003 | PC | 4.0.4 | Original | | MCHM4PIT81 | |
| Scudetto 5 Scudetto Championship Manager 5 | XBOX | | Original | | ES-026 | |
| Scudetto 5 Scudetto Championship Manager 5 | PS2 | 1.02 | Original | | SLES-53222 | |
| SD Gundam GGeneration Overworld SDガンダム ジージェネレーション オーバーワールド | PSP | 1.01 | Original | | ULJS 00536 | |
| SD Gundam: GCentury S SDガンダム・ジー・センチュリーS | SS | 1.001 | Original | | T-13324G | |
| SD Gundam: GGeneration SD 건담: G-제네레이션 | PC | 1.0.0.1 | Original | | | |
| SD Gundam: GGeneration DA SDガンダム GジェネレーションDA | PC | 1.00 | DigiCube PC Series | | DWRMS-00158 | |
| SD Gundam: GGeneration DA SDガンダム GジェネレーションDA | PC | 1.1.0.29 | Original | | BSE-2002 | |
| SD Gundam: GGeneration Neo SD 건담 지 제네레이션 네오 | PS2 | 1.01 | Original | | SLKA 25081 | |
| SD Gundam: GGeneration Seed SD 건담 지제네레이션 시드 | PS2 | 1.01 | Original | | SLKA 25170 | |
| SD Gundam: GGeneration Wars SDガンダム ジージェネレーション ウォーズ | WII | | Original | | RVL-R77J-JPN | |
| SD Gundam: GGeneration Wars SDガンダム ジージェネレーション ウォーズ | PS2 | 1.03 | Original | | SLPS 25941 | |
| SD Gundam: GGeneration Wars SD 건담 G제너레이션 워즈 | PS2 | 2.00 | Original | | SCKA 20139 | |
| SD Gundam: GGeneration World SDガンダム ジージェネレーション ワールド | WII | | Original | | RVL-SDJJ-JPN-B0 | |
| SD Gundam: GGeneration-0 (Disc 1) SDガンダム ジージェネレーション・ゼロ | PSX | Rev 1 | Bandai the Best | | SLPS 03206 | |
| SD Gundam: GGeneration-0 (Disc 2) SDガンダム ジージェネレーション・ゼロ | PSX | Rev 1 | Bandai the Best | | SLPS 03207 | |
| SD Gundam: GGeneration-F (Disc 1) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84004 | |
| SD Gundam: GGeneration-F (Disc 2) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84005 | |
| SD Gundam: GGeneration-F (Disc 3) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84006 | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Limited Edition | | SLPS 02903 | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84007 | |
| SD Gundam: GGeneration-F.I.F SDガンダム ジージェネレーション・エフイフ | PSX | | Original | | SLPS 03195 | |
| SDevTC: Version 2 | PC | 2 | Original | | | |
| SDevTC: Version 2.4 | PC | 2.4 | Original | | DTL-S2200 | |
| SDS Star Divers スターダイバーズ | PC | | Original | | CS001 | |
| Sea Adventures | PC | | Microforum | | | |
| Sea Battle | PC | | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Sold Out Software | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7P-EUR | |
| Sea Monsters: A Prehistoric Adventure National Geographic: Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLES-55046 | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLUS-21741 | |
| Sea War Sea War: Entscheidungsschlacht im Pazifik | PC | | Original | | SPI 023 | |
| SeaBass Fishing シーバス・フィッシング | SS | 1.001 | Original | | T-6005G | |
| SeaBlade | XBOX | | Original | | TM-009 | |
| Seafight II | PC | | Original | | | |
| Seal: Travelers of Destiny SEAL~運命の旅人~ | PC | | Original | | MKD-1390 | |
| Seaman Esa Disc: Kimos Shu no Youchuu Hojuu Kit シーマン えさ ディスク <キモス種の幼虫補充キット> | DC | 1.001 | Bundled with Seaman Ikusei Shien Kit | | 610-7804 | |
| Seaman: Kindan no Pet: Kanzenban シーマン ~禁断のペット~ 〈完全版〉 | PS2 | 1.04 | Sea-Mic Controller Doukonban | | SLPM 65217 | |
| Search & Destroy | PS2 | 1.01 | Original | | SLES-54033 | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| Seasons Greetings from Philips Media | CDI | | Original | | | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLES-53804 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLUS 21289 | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| The Second Guest | PC | | Original | | | |
| Second Sight | PC | | Bundle Version ASUS OEM | | V468 | |
| Second Sight | PC | | Original | | | |
| Second Sight | PC | | 1C: Kollekciya igrushek | | | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Secre Volume 4: Hitomi Fujisaki SECRE VOLUME ④ 「藤崎 仁美」 | FMT | | Original | | HME-196 | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Volume 6: Reiko Kato SECRE VOLUME ⑥ 「かとう れいこ」 | FMT | | Original | | HME-205 | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Agent Clank | PSP | 1.01 | Original | | UCAS-40218 | |
| Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
| Secret Agent Clank Clank: Agente-Secreto | PSP | 0.01 | Review | | UCET-01101 | |
| Secret Agent Clank 시크릿 에이전트 클랭크 | PSP | 1.00 | Original | | UCKS 45096 | |
| Secret Agent Clank | PSP | .01 | Beta | | UCUS-98697 | |
| Le Secret du Templier | MAC | 1.0 | Covermount | | | |
| Secret Files 2: Puritas Cordis | WII | | | | RVL-RZFP-EUR | |
| Secret Files 2: Puritas Cordis | PC | | Original | | ECD900341D | |
| Secret Files: Il Mistero di Tunguska | PC | 1.00 | Covermount | | | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUP-EUR | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| Secret Game: Killer Queen シークレットゲーム -KILLER QUEEN- | PS2 | 1.02 | Original | | SLPM 55028 | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| Secret Mission | CDI | | Original | | 810 0272 | |
| Secret Mission | CDI | 1.01 | Beta | | 810 0272 | |
| Secret Mission | CDI | 1.07 | Original | | 812 0053 | |
| Secret Mission | CDI | 1.06 | Original | | 813 0160 | |
| Secret Mission | CDI | | Original | | 814 0133 | |
| The Secret of Googol 2: Reshaping Googol: Castle / Ocean | PC | 2.0 | Original | | | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PC | 2.0 | Original | | | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island モンキー・アイランド | FMT | | Original | | HMD-155 | |
| The Secret of Monkey Island モンキー・アイランド ~ユーレイ海賊大騒動!~ | MCD | | Original | | T-60044 | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| The Secret of the Nautilus | PC | | Original | | JVEENCD1 | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| Secret of Video Architecture X68000画面表示仕様の秘密 | X68K | | Original | | | |
| Secret Safari シークレットサファリ | PC | | Original | | VIRL-8 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85P-EUR-B0 | |
| The Secret Saturdays: Beasts of the 5th Sun | PSP | 1.01 | Original | | ULES-01363 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| The Secret Saturdays: Beasts of the 5th Sun | PSP | 1.00 | Original | | ULUS-10443 | |
| The Secret Saturdays: Beasts of the 5th Sun | PS2 | 1.01 | Original | | SLUS-21896 | |
| Secret Service | PS2 | 1.00 | Original | | SLES-55330 | |
| Secret Service | XBOX360 | | Original | | AV-2084 | |
| Secret Service | PS2 | 1.01 | Original | | SLUS 21836 | |
| Secret Service CD 36 | PC | | | | | |
| Secret Service CD 37 | PC | | | | | |
| Secret Service CD 38 | PC | | | | | |
| Secret Service CD 39 | PC | | | | | |
| Secret Service CD 40 | PC | | | | | |
| Secret Service CD 43 | PC | | | | | |
| Secret Service CD 44 (Strona A) | PC | | | | | |
| Secret Service CD 44 (Strona B) | PC | | | | | |
| Secret Service CD 45 | PC | | | | | |
| Secret Service CD 47 (Strona A) | PC | | | | | |
| Secret Service CD 47 (Strona B) | PC | | | | | |
| Secret Service CD 48 (Strona B) | PC | | | | | |
| Secret Service CD 49 (Strona A) | PC | | | | | |
| Secret Service CD 49 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona A) | PC | | | | | |
| Secret Service CD 50 (Strona B) | PC | | | | | |
| Secret Service CD 51 (Strona B) | PC | | | | | |
| Secret Service CD 52 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona B) | PC | | | | | |
| Secret Service CD 53 (Strona A) | PC | | | | | |
| Secret Service CD 53 (Strona B) | PC | | | | | |
| Secret Service CD 60 | PC | | | | | |
| Secret Service CD 61 | PC | | | | | |
| Secret Service CD 64 | PC | | | | | |
| Secret Service CD 87 | PC | | | | | |
| Secret Service CD 88 | PC | | | | | |
| Secret Service CD 89 | PC | | | | | |
| Secret Service CD 90 | PC | | | | | |
| Secret Service CD 91 | PC | | | | | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Weapons of the Luftwaffe | PC | | Collezione CD-Rom by C.T.O. | | | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 32609.101.UK | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 32609.102.UK | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 32609.103.UK | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 32609.104.UK | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51708 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51709 | |
| Secret Weapons over Normandy (Disc 1) | PC | | Original | | 32609.101.GM | |
| Secret Weapons over Normandy (Disc 2) | PC | | Original | | 32609.102.GM | |
| Secret Weapons over Normandy (Disc 3) | PC | | Original | | 32609.103.GM | |
| Secret Weapons over Normandy (Disc 4) (Spiel-CD) | PC | | Original | | 32609.104.GM | |
| Secret Weapons over Normandy (Disco 1) | PC | 1.0 | Original | | 32609.101.IT | |
| Secret Weapons over Normandy (Disco 2) | PC | 1.0 | Original | | 32609.102.IT | |
| Secret Weapons over Normandy (Disco 3) | PC | 1.0 | Original | | 32609.103.IT | |
| Secret Weapons over Normandy (Disco 4) (Disco di Gioco) | PC | 1.0 | Original | | 32609.104.IT | |
| Secret Weapons over Normandy シークレット・ウェポン・オーバー・ノルマンディ | PS2 | 1.01 | Original | | SLPM 65483 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51711 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.00 | Review Build | | SLUS-20762 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLUS 20762 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secret World (Disc 1) | PC | | Original | | EAX07709446D | |
| The Secret World (Disc 2) | PC | | Original | | EAX07709446D2 | |
| Les Secrets d'Alamut (Disc 1) | PC | | Original | | ALAFR1P | |
| Les Secrets d'Alamut (Disc 2) | PC | | Original | | ALAFR2P | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 2) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Dark: Der finstere Berg | PC | | Original | | | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Section 8: Prejudice | PS3 | 01.00 | Beta | | | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| The Seed シード | PS2 | 1.03 | Original | | SLPS 20144 | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy | PC | | Original | | CDR3015 | |
| Seek and Destroy Seek & Destroy | CD32 | | Original | | | |
| Sega Ages 2500 Series Vol. 16: Virtua Fighter 2 SEGA AGES 2500シリーズ Vol.16 バーチャファイター2 | PS2 | 1.00 | Original | | SLPM 62547 | |
| Sega Ages 2500 Series Vol. 19: Fighting Vipers SEGA AGES 2500シリーズ Vol.19 ファイティングバイパーズ | PS2 | 1.01 | Original | | SLPM 62606 | |
| Sega Ages 2500 Series Vol. 20: Space Harrier II: Space Harrier Complete Collection SEGA AGES 2500シリーズ Vol.20 スペースハリアーII ~スペースハリアーコンプリートコレクション~ | PS2 | 1.00 | Original | | SLPM 62691 | |
| Sega Ages 2500 Series Vol. 21: SDI & Quartet: Sega System 16 Collection セガエイジス2500シリーズ Vol.21 SDI & カルテット -SEGA SYSTEM 16 COLLECTION- | PS2 | 1.00 | Original | | SLPM 62692 | |
| Sega Ages 2500 Series Vol. 22: Advanced Daisenryaku: Deutsch Dengeki Sakusen セガ・エイジス2500シリーズVol.22 アドバンスド大戦略 ~ドイツ電撃作戦~ | PS2 | 2.00 | Original | | SLPM 62708 | |
| Sega Ages 2500 Series Vol. 22: Advanced Daisenryaku: Deutsch Dengeki Sakusen セガエイジス2500シリーズ Vol.22 アドバンスド大戦略 ~ドイツ電撃作戦~ | PS2 | 3.00 | Shuusei-ban | | SLPM 62708 | |
| Sega Ages 2500 Series Vol. 23: Sega Memorial Selection セガエイジス2500シリーズ Vol.23 セガメモリアルセレクション | PS2 | 1.01 | Original | | SLPM 62709 | |
| Sega Ages 2500 Series Vol. 24: Last Bronx: Tokyo Bangaichi セガエイジス2500シリーズ Vol.24 ラストブロンクス 東京番外地 | PS2 | 1.01 | Original | | SLPM 62687 | |
| Sega Ages 2500 Series Vol. 25: Gunstar Heroes: Treasure Box セガエイジス2500シリーズ Vol.25 ガンスターヒーローズ ~トレジャーボックス~ | PS2 | 1.01 | Original | | SLPM 62712 | |
| Sega Ages 2500 Series Vol. 26: Dynamite Deka セガ・エイジス2500シリーズ Vol.26 ダイナマイト刑事 | PS2 | 1.01 | Original | | SLPM 62717 | |
| Sega Ages 2500 Series Vol. 30: Galaxy Force II: Special Extended Edition セガエイジス2500シリーズ Vol.30 ギャラクシーフォースⅡ ~スペシャルエクステンデッドエディション~ | PS2 | 1.00 | Original | | SLPM 62766 | |
| Sega Ages 2500 Series Vol. 31: Dennou Senki: Virtual On SEGA AGES 2500 シリーズ Vol.31 電脳戦機バーチャロン | PS2 | 1.01 | Original | | SLPM 62767 | |
| Sega Ages 2500 Series Vol. 33: Fantasy Zone Complete Collection セガ・エイジス2500シリーズVol.33 ~ファンタジー・ゾーン・ コンプリート・コレクション~ | PS2 | 1.00 | Original | | SLPM 62780 | |
| Sega Ages 2500 Series Vol. 6: Ichini no Tant-R to Bonanza Bros. セガエイジス2500シリーズ Vol.6 イチニのタントアールとボナンザブラザーズ | PS2 | 1.03 | Renkaban | | SLPM 62671 | |
| Sega Ages 2500 Series Vol. 8: Virtua Racing: FlatOut セガ・エイジス2500シリーズVol.8 ~V.R. バーチャレーシング フラットアウト~ | PS2 | 1.03 | Original | | SLPM 62443 | |
| Sega Ages 2500 Taikenban SEGA AGES 2500 体験版 | PS2 | 1.01 | Taikenban | | SLPM 61077 | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Ages: Memorial Selection Vol. 1 セガエイジス メモリアル・セレクションVOL.1 | SS | 1.002 | Original | | GS-9135 | |
| Sega Ages: Rouka ni Ichidanto R セガエイジス 廊下にイチダントアール | SS | 1.002 | Original | | GS-9043 | |
| Sega Ages: Shukudai ga Tanto R セガエイジス 宿題がタントアール | SS | 1.06 | Original | | GS-9042 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Extreme Sports セガ エクストリーム スポーツ | DC | 1.003 | Original | | HDR-0146 | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original | | EI-1266-1 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original | | EI-1266-1 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega GT 2002 | XBOX | | Original | | IG-044 | |
| Sega GT 2002 | XBOX | | Demo | | SE-003 | |
| Sega GT 2002 sega GT 2002 | XBOX | | Original | | SE-003 | |
| Sega GT 2002 | XBOX | | Original | | SE-003 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future 세가 GT 2002 + 젯 셋 라디오 퓨처 · 噴射小子 未來版 | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT Online | XBOX | | Beta | | | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega GT Online sega GT Online | XBOX | | Original | | SE-033 | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega GT: Homologation Special セガGT ホモロゲーションスペシャル | DC | 0.800 | Taikenban | | 610-7727 | |
| Sega Hard Historia セガハードヒストリーア | PC | | Book Bundle | | | |
| Sega Mega Drive Classic Collection Volume 3 | PC | | Original | | SEGA-PC120 | |
| Sega Mega Drive Classic Collection: Złota Edycja | PC | 1.0.019 | Platynowa Kolekcja | | P_37010_04A_PL | |
| Sega Memorial Selection: Dear 80's Videogame Best 3 | PC | | Ultra 2000/Ultra Series | | MKW-183 | |
| Sega Net Mahjong MJ Arcade セガNET麻雀MJ Arcade | SRE | | Original | | DVR-5055D | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 4.000 | Original | | GDX-0006C | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 5.000 | Original | | GDX-0006D | |
| Sega Network Taisen Mahjong MJ3 セガ・ネットワーク対戦麻雀MJ3 | CHIHIRO | 5.000 | Original | | GDX-0017D | |
| Sega Network Taisen Mahjong MJ3 Evolution セガ・ネットワーク対戦麻雀MJ3 EVOLUTION | CHIHIRO | 2.000 | Original | | GDX-0021A | |
| Sega Network Taisen Mahjong MJ3 Evolution-you Firmware Koushin Program セガ・ネットワーク対戦麻雀MJ3 EVOLUTION用ファームウェア更新プログラム | CHIHIRO | 1.000 | Original | | GDX-0023 | |
| Sega Network Taisen Mahjong MJ4 セガネットワーク対戦麻雀MJ4 | LINDBERGH | 8.003 | Original | | DVP-0049G | |
| Sega Network Taisen Mahjong MJ4 Evolution セガネットワーク対戦麻雀MJ4 Evolution | LINDBERGH | | Original | | DVP-0081 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083D | |
| Sega PC Collection Vol. 2 | PC | | PC Game Bundle | | 673-04572 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Rally Championship Plus Netlink Edition | SS | 1.001 | Net Link Game Pack | | 81215, 81608 | |
| Sega Saturn Development Tool Kit | PC | | Original | | 610-5750 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Sports Tennis | PS2 | 1.01 | Original | | SLUS 20480 | |
| Sega Superstars Exclusive Sonic Sega Superstars Demo | PS2 | 1.01 | Demo | | SLED-52875 | |
| Sega Superstars EyeToy Sega Superstars | PS2 | 1.00 | Original | | SLES-52885 | |
| Sega Superstars セガ スーパースターズ | PS2 | 1.01 | EyeToy Camera Doukonban | | SLPM 62554 | |
| Sega Superstars セガ スーパースターズ | PS2 | 1.01 | Original | | SLPM 62559 | |
| Sega Superstars | PS2 | 1.00 | Original | | SLUS 20999 | |
| Sega Superstars Tennis | PS3 | 01.01 | Original | | BLES-00232 | |
| Sega Tetris セガテトリス | DC | 2.000 | Original | | HDR-0073 | |
| Sega Touring Car Championship 世嘉巡回车大赛 | PC | | Original | | | |
| Sega Touring Car Championship | PC | | Fair Game: Quality Value | | FG-1306 EUROPEAN | |
| Sega Touring Car Championship | PC | 1.0 | Expert Software | | 681301.201.UK 01 | |
| Sega Touring Car Championship | PC | 1.0 | Xplosiv | | EI-1306 | |
| Sega Touring Car Championship セガ・ツーリングカーチャンピオンシップ | SS | 1.002 | Taikenban (Bundled with Sega Touring Car Championship OST) | | 610-6747 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.003 | Original | | MK81123-50 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.004 | Original | | MK81123-50 | |
| Sega Worldwide Soccer 2000: Euro Edition SWWS 2000: Euro Edition | DC | 1.030 | Original | | MK-51083-50 | |
| SegaColle Sega Bible Mogitate SegaSaturn Soukan-gou セガコレセガバイブルモギタテセガサターン。 創刊号 1997.11 | SS | 1.000 | Hibaihin | | 610-6805-01 | |
| SegaKara for Dreamcast セガカラ for ドリームキャスト | DC | 1.002 | Bundled with Dreamcast Karaoke | | 610-7762 | |
| SegaSaturn Electronic Book Operator セガサターン 電子ブック・オペレーター | SS | 1.00C | Original | | HSS-0120 | |
| SegaSaturn FDD Operator セガサターン FDDオペレーター | SS | 1.003 | Bundled with SegaSaturn FDD | | HSS-0128 | |
| SegaSaturn Internet 2 SEGASATURN インターネット 2 | SS | 1.030 | Bundled with SegaSaturn Modem | | T-31302G | |
| SegaSaturn Internet Vol. 1 SEGASATURN インターネット Vol.1 | SS | 1.000 | Bundled with SegaSaturn Modem | | T-31301G | |
| SegaSaturn Photo CD Operator セガサターン フォトCDオペレーター | SS | 1.007 | Original | | HSS-0121 | |
| SegaSaturn: Graphic & Sound Tools for Macintosh | SS | | Original | | N16-1000 | |
| SegaSaturn: Movie Tools: Cinepak for Sega Saturn | SS | | Hybrid Version | | L17-1000 | |
| SegaSaturn: SGL Tool Kit: Sega 3D Game Library | SS | 1.000 | Original | | L15-1000 | |
| Sei Shirasagi Jogakuen Vol. 2: Tsukahara Shiho-hen 聖シラサギ女学園 Vol.2 塚原 シホ編 | PC | | Original | | SCR-1997-02 | |
| Seifuku Densetsu: Pretty Fighter X 制服伝説 プリティ・ファイターX | SS | 1.002 | Original | | T-15001G | |
| Seigi no Mikata 正義の味方 | PS2 | 1.02 | Original | | SCPS 11016 | |
| Le Seigneur des Anneaux: Le Retour du Roi | XBOX | | Original | | EA-062 | |
| Le Seigneur des Anneaux: Le Retour du Roi | PS2 | 1.00 | Original | | SLES-52019 | |
| Le Seigneur des Anneaux: Le Tiers Age | XBOX | | Original | | EA-095 | |
| Le Seigneur des Anneaux: Le Tiers Age | PS2 | 1.00 | Original | | SLES-52802 | |
| Le Seigneur des Anneaux: Les Deux Tours | PS2 | 1.00 | Original | | SLES-51253 | |
| Le Seigneur des Anneaux: Tactics | PSP | 1.00 | Original | | ULES-00199 | |
| Seikai Risshiden: Yoi Kuni, Yoi Seiji 政界立志伝 ~よい国・よい政治~ | SS | 1.003 | Original | | T-18005G | |
| Seikimatsu Taimaden Tsumugi-chan SOS 世紀末退魔伝つむぎちゃんSOS | PC | | Original | | EXC-0011 | |
| Seiryuu Densetsu: Monbit 聖竜伝説モンビット | PCE | Rev 4 | Original | | HCD1018 | |
| Seisenshi Denshou: Jantaku no Kishi 聖戦士伝承 ~雀卓の騎士~ | PCE | | Original | | NBCD4005 | |
| Seishoujo Kantai Virgin Fleet 聖少女艦隊・バージン・フリート | PSX | | Original | | SLPM 86191 | |
| Seitai Heiki Expendable 生体兵器 エクスペンダブル | DC | 1.001 | Original | | T-15003M | |
| Seiya Monogatari: Anearth Fantasy Stories 聖夜物語 | PCE | Rev 2 | Original | | HCD5071 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 1) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 2) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Sekai Fushigi Hakken! Troia 世界ふしぎ発見! トロイア | DC | 1.002 | Original | | T-39701M | |
| Sekai no Subete: Two of Us 世界ノ全テ -two of us- | PS2 | 1.02 | Original | | SLPM 66544 | |
| Sekai Saikyou Ginsei Igo: Hybrid Monte Carlo 世界最強銀星囲碁 ハイブリッドモンテカルロ | PS3 | 01.00 | Original | | BLJS 10096 | |
| Selection 2000 Dai-10-Dan: Osaka Ennichi セレクション2000 第10弾 大阪縁日 | PC | OE1-2V1.00 | Selection 2000 | | SSA0010 | |
| Selector Demo 01 | PS2 | 1.10 | | | SCED-50811 | |
| Selector Demo 03 PlayStation 2 Official Demo Disc Retail Edition 3 | PS2 | 1.00 | | | SCED-51146 | |
| Selector Demo 04 PlayStation 2 Official Demo Disc Retail Edition 4 | PS2 | 1.00 | | | SCED-51269 | |
| Selector Demo 05 Selector Demo 05 April 2003: June 2003 | PS2 | 1.00 | | | SCED-51683 | |
| Selector Demo 06 PlayStation 2 Official Demo Disc Retail Edition 6 | PS2 | 1.00 | | | SCED-51596 | |
| Selector Demo 08 PlayStation 2 Official Demo Disc Retail Edition 8 | PS2 | 1.01 | | | SCED-51598 | |
| Selector Demo 7 PlayStation 2 Official Demo Disc Retail Edition 7 | PS2 | 1.00 | | | SCED-51597 | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Sengoku Anthology | PS2 | 1.02 | Original | | SLES-55512 | |
| Sengoku Basara 3: Utage 戦国BASARA3 宴 | WII | | Original | | RVL-S3HJ-JPN-B0 | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! 戦国美少女絵巻 空を斬る!! | PC | | Original | | TGL-98 0220 | |
| Sengoku Blade: Sengoku Ace Episode II 戦国ブレード | SS | 1.002 | Mihonhin | | ST-14410G | |
| Sengoku Efuda Yuugi: Hototogisu Ran 戦国絵札遊戯 不如帰 乱 | PSP | 1.02 | Original | | ULJS 00159 | |
| Sengoku Efuda Yuugi: Hototogisu Tairan 戦国絵札遊戯 不如帰 大乱 | PSP | 1.02 | Original | | ULJS 00326 | |
| Sengoku Musou 2 with Moushouden 戦国無双2 with 猛将伝 | XBOX360 | | Original | | KO-2005 | |
| Sengoku Musou 2 with Moushouden & Empires HD Version 戦国無双2 with 猛将伝 & Empires HD Version | PS3 | 01.01 | Original | | BLJM 61092 | |