Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sesame Street: Ready, Set, Grover! with Elmo: The Videogame | WII | | Original | | RVL-SESE-USA-B0 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Let's Make a Word! | PC | | | | 7418 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam HD | XBOX360 | | Promo | | MK-2004 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| The Serious Sam Collection | XBOX360 | | Original | | MK-2010 | |
| Sequence Palladium Premium Digital Novel | PC | | PC Game Bundle | | KGD-06021 | |
| Sequence Palladium Mania Kit: Desktop Accessory シークエンス・パラディウム マニアキット デスクトップアクセサリ | PC | | Original | | WIC-6346 | |
| Sento Monogatari: Sono I 「占都物語」 そのI | PC | | Original | | | |
| Sentient | PC | | Original | | | |
| Senkaku Mondai o Yatchimasu 2 尖閣問題を殺っちます2 | PC | | Original | | | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc 戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senha N. 1 | PC | | | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Taikenban Special Disc | | SLPM 80271 | |
| SegaSaturn: Movie Tools: Cinepak for Sega Saturn | SS | | Hybrid Version | | L17-1000 | |
| SegaSaturn: Graphic & Sound Tools for Macintosh | SS | | Original | | N16-1000 | |
| Sega Soccer Slam | XBOX | | Original | | SE-020 | |
| Sega Soccer Slam セガ サッカースラム | GC | | Original | | DL-DOL-GSSJ-JPN | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Saturn Development Tool Kit | PC | | Original | | 610-5750 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Mihon-hin | | 670-10314 | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Racing Classic | SRE | | RingWide | | DVR-0009A | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | PC Game Bundle | | 670-11970 | |
| Sega PC Collection Vol. 1 | PC | | PC Game Bundle | | 673-04569 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083 | |
| Sega Network Taisen Mahjong MJ5 R Evolution セガネットワーク対戦麻雀MJ5 R EVOLUTION | SRE | | Original | | DVR-0083D | |
| Sega Network Taisen Mahjong MJ5 Evolution セガネットワーク対戦麻雀MJ5 EVOLUTION | SRE | | Original | | DVR-0071 | |
| Sega Network Taisen Mahjong MJ5 セガネットワーク対戦麻雀MJ5 | SRE | | Original | | DVR-0027 | |
| Sega Net Mahjong MJ Arcade セガNET麻雀MJ Arcade | SRE | | Original | | DVR-5055D | |
| Sega GT Online | XBOX | | Beta | | | |
| Sega GT 2002 + JSRF: Jet Set Radio Future 세가 GT 2002 + 젯 셋 라디오 퓨처 · 噴射小子 未來版 | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT 2002 | XBOX | | Demo | | SE-003 | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega Game Honpo: Puyo Puyo セガゲーム本舗 ぷよぷよ | PC | | Original | | | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega CD Demo | MCD | | Prototype | | | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Service CD 91 | PC | | | | | |
| Secret Service CD 90 | PC | | | | | |
| Secret Service CD 89 | PC | | | | | |
| Secret Service CD 88 | PC | | | | | |
| Secret Service CD 87 | PC | | | | | |
| Secret Service CD 64 | PC | | | | | |
| Secret Service CD 61 | PC | | | | | |
| Secret Service CD 60 | PC | | | | | |
| Secret Service CD 53 (Strona B) | PC | | | | | |
| Secret Service CD 53 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona B) | PC | | | | | |
| Secret Service CD 52 (Strona A) | PC | | | | | |
| Secret Service CD 51 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona A) | PC | | | | | |
| Secret Service CD 49 (Strona B) | PC | | | | | |
| Secret Service CD 49 (Strona A) | PC | | | | | |
| Secret Service CD 48 (Strona B) | PC | | | | | |
| Secret Service CD 47 (Strona B) | PC | | | | | |
| Secret Service CD 47 (Strona A) | PC | | | | | |
| Secret Service CD 45 | PC | | | | | |
| Secret Service CD 44 (Strona B) | PC | | | | | |
| Secret Service CD 44 (Strona A) | PC | | | | | |
| Secret Service CD 43 | PC | | | | | |
| Secret Service CD 40 | PC | | | | | |
| Secret Service CD 39 | PC | | | | | |
| Secret Service CD 38 | PC | | | | | |
| Secret Service CD 37 | PC | | | | | |
| Secret Service CD 36 | PC | | | | | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| Secret of Video Architecture X68000画面表示仕様の秘密 | X68K | | Original | | | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Files 2: Puritas Cordis | WII | | | | RVL-RZFP-EUR | |
| Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
| Secre Volume 5: Tina Gushiken SECRE VOLUME ⑤ 「具志堅 ティナ」 | FMT | | Sample | | HME-204 | |
| Secre Demo Disk | FMT | | Hibaihin | | HME-921 | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Second Sight | PC | | Bundle Version ASUS OEM | | V468 | |
| The Second AMUC CD | ACD | | | | CDRM1251610 | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| Seasons Greetings from Philips Media | CDI | | Original | | | |
| Search for the Sea | VIS | | Original | | 25-6143 | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| SeaBlade | XBOX | | Original | | VU-023 | |
| Sea Rescue | PC | | Nestlé Corn Flakes | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7P-EUR | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84007 | |
| SD Gundam: GGeneration-F (Disc 3) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84006 | |
| SD Gundam: GGeneration-F (Disc 2) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84005 | |
| SD Gundam: GGeneration-F (Disc 1) SDガンダム ジージェネレーション・エフ | PSX | | Koudansha 8-shi Rengou Kikaku Tokubetsu-ban | | SLPM 84004 | |
| SD Gundam: Gashapon Wars SDガンダム ガシャポンウォーズ | GC | | Taikenban | | DL-DOL-PGPJ-JPN | |
| The Scroll Daughter of Serpents | PC | | Original | | | |
| The Scroll | PC | | | | | |
| Scribblenauts Unlimited (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Screendisc Interactive Preview Systems: The Preview System | CDI | | Original | | | |
| Screen Fighter Screen Saver スクリーンファイター スクリーンセーバー | PC | | Original | | SRC-00001 | |
| Screaming Skies | PC | | Tewi | | Bestell-Nr. 27669 | |
| Screamer Rally | PC | | Covermount | | G02 | |
| Screamer 4x4 | PC | | Covermount | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer | PC | | Sold Out Extreme | | | |
| Scramble Cobra: Premium Version スクランブル・コブラ プレミアム・バージョン | 3DO | | Not for Sale | | FZ-JJ9PSC-5H | |
| Scramble Cobra | 3DO | | Beta (CD-R) | | | |
| Scramble Cobra スクランブル・コブラ | 3DO | | Demonstration-ban | | FZ-JJ9DSP-5G | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| Scrabble CD-ROM | PC | | Original | | 23713-0726 Rev a | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| Score International Baja 1000: The Official Game | WII | | Original | | RVL-RJCE-USA | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooby-Doo! Unmasked | GC | | Original | | DL-DOL-G5DE-USA | |
| Scooby-Doo! Pierwsze Strachy | PC | | Demo | | | |
| Scooby-Doo! Night of 100 Frights | PSX | | Prototype | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Les Civilisations Perdues | VFLASH | | Original | | 093085(FR) | |
| Scooby-Doo! Fluch der Folianten | GC | | Original | | DL-DOL-GC3D-NOE | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093083(UK) | |
| Scooby Doo: Strachy na Lachy | PC | | | | | |
| Science Is Elementary 3 | PSX | | Original | | LSP-990163 … | |
| Science Is Elementary 2 | PSX | | Original | | LSP-990162 … | |
| Science Is Elementary 1 | PSX | | Original | | LSP-990161 … | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| SCI Media Kit: Version: 2 | PC | | Press Kit | | | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | MAC | | Original | | 9227 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| Die Schönsten Hotels der Welt | PHOTO-CD | | Original | | 813 0060 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus Explores the Ocean | MAC | | Original | | 0496 Part No. 64964 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Schleichfahrt | PC | | Original | | | |
| Schleichfahrt | PC | | | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schiff-Simulator 2008 Ship Simulator 2008 | PC | | Original | | | |
| Scene Xplorer '97 Scene Explorer: From the Beginning into the Future | ACD | | Original | | | |
| Scene Storm | ACD | | | | | |
| Scene It? Luces, Cámara, ¡Acción! Scene It? Bright Lights! Big Screen! | XBOX360 | | Bundled with 4 Controllers | | MS-2098 | |
| A Scene It? Lights, Cameraction! A Scene It? Luci, Camerazione! Il gioco a quiz sul cinema | XBOX360 | | Original | | MS-2098 | |
| A Scene It? Lights, Cameraction | XBOX360 | | Original | | MS-2098 | |
| Scene It? Grandes Éxitos de Taquilla | XBOX360 | | Original | | MS-2144 | |
| Scene It? Ganz großes Kino! | WII | | Original | | RVL-SSCD-NOE-B0 | |
| Scene It? Ganz großes Kino! | XBOX360 | | Original | | WR-2040 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2037 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCE-USA-B0 | |
| Scene It? Box Office Smash! Scene It? Campione d'Incassi: Nuovissimi filmati e quiz sul cinema | XBOX360 | | Original | | MS-2144 | |
| The Scene Archive: 1988-1998 | ACD | | Original | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 2) | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 1) | PC | | Press Kit | | | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| Scavenger 4 スカベンジャー4 | FMT | | Demo-ban | | HME-918 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 300202 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCE-USA | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Scan & Teach: Thema 7-12: Klasse 3 | CDI | | Original | | | |
| Scan & Teach: Thema 1-6: Klasse 3 | CDI | | Original | | | |
| Scaler | GC | | Original | | DL-DOL-GKUE-USA | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 2) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 1) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| SBK: Superbike World Championship | XBOX360 | | Original | | CN-2005 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK Generations | XBOX360 | | Original | | LS-2033 | |
| SBK 09: Superbike World Championship | XBOX360 | | Original | | LS-2004 | |
| SBK 08: Superbike World Championship | XBOX360 | | Original | | LS-2001 | |
| SBFR the Best 4: PKMN First History | PC | | Original | | SSEB-0055 | |
| SBFR the Best 3: Kirby First History | PC | | Original | | SSEB-0054 | |
| SBFR the Best 2: White | PC | | Original | | SSEB-0041 | |
| SBFR the Best 2: Black | PC | | Original | | SSEB-0042 | |
| Sayonara さよなら 体験版 | PC | | Taikenban | | | |
| Say What You Want | CDI | | Original | | | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Satsui no Shoumei: In the 1st Degree: Making CD-ROM 殺意の証明 イン ザ ファースト ディグリー メイキングCD-ROM | PC | | Hibaihin | | IP-081M | |
| Satsui no Shoumei: In the 1st Degree (Disc 2) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078B | |
| Satsui no Shoumei: In the 1st Degree (Disc 1) 殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078A | |
| SAT.1 Swing | PC | | Original | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | Original | | | |
| SAS: Secure Tomorrow | PC | | Covermount | | | |
| Saru! Get You! サルゲッチュ | PSX | | Tentou-you Taikenban | | PCPX 96166 | |
| Sargon V: World Class Chess サルゴンⅤ | FMT | | Original | | HMD-191 | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| Santa Claus Is Comin' to Town! | WII | | Original | | RVL-SX5E-USA-B0 | |
| Sansuu Senshi Blaster: Anzan Power de Spot-kun o Sukue! 算数戦士ブラスター 暗算パワーでスポット君を救え! | PC | | Original | | | |
| Sanrio Tiny Park Vol. 2 サンリオ タイニー・パーク Vol.2 | PC | | | | RS-9 | |
| Sanrio Puroland Carnival サンリオピューロランド カーニバル | PC | | | | RS-13 | |
| Sanrio Character Encyclopedia サンリオキャラクター大百科 | PC | | | | R-10 | |
| Sanitarium | PC | | Demo | | | |
| Sanguozhi V 三國志Ⅴ | PSX | | Zhongwenban | | SCPS 45128 | |
| Sanguozhi IV 三國志Ⅳ | PC | | Original | | | |
| Sanguozhi IV 三國志Ⅳ | PSX | | Original | | SCPS 45003 | |
| Sanguo Zhi Xinghai Fengyun (Disc 2) 三國之星海風雲 | PC | | Original | | | |
| Sanguo Zhi Xinghai Fengyun (Disc 1) 三國之星海風雲 | PC | | Original | | | |
| Sanguo Yinghao 三國英豪 | PC | | Original | | | |
| Sanguo Qunyingzhuan IV Ziliao Sheding 三国群英传Ⅳ 资料设定 | PC | | Bundled with Book | | | |
| Sangokushi Koumeiden 三國志孔明傳 | PC | | Original | | | |
| Sangokushi Battlefield 三國志 Battlefield | PC | | βversion | | β-17292 | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sanae-chan wa Torawarete Shimatta! (Disc 1) さなえチャンは囚われてしまった! | PC | | Original | | | |
| San Francisco Rush The Rock: Alcatraz Edition | PC | | Bundle Version Quantum3D OEM | | 740-0033-01 #QM049 | |
| Samurai Warriors: Katana | WII | | Beta | | | |
| Samurai Warriors: Katana | WII | | Original | | RVL-RS5P-EUR | |
| Samurai Warriors 2: Empires | XBOX360 | | Original | | KO-2006 | |
| Samurai Warriors | XBOX | | Original | | KO-006 | |
| Samurai Warriors | XBOX | | Original | | KO-006 | |
| Samurai Shodown Sen | XBOX360 | | Original | | SN-2005 | |
| Samurai Shodown III | PSX | | Original | | SCES-00563 | |
| Samurai Shodown | MCD | | Bundled with Magazine (Demo) | | | |
| Samurai Jack: The Shadow of Aku | GC | | Original | | DL-DOL-GJCE-USA | |
| Samgukji II 2000 Plus 三國志Ⅱ 2000 PLUS | PC | | Original | | | |
| Samba World Cup | ACD | | Original | | | |
| Sam & Max: This Time It's Virtual! | PC | | Limited Run Games | | | |
| Sam & Max: Season One | WII | | Beta | | | |
| Sam & Max: Season One | PC | | Covermount | | | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YE-USA-B0 | |
| Sam & Max: Beyond Time and Space | WII | | Original | | RVL-R3YP-EUR-B0 | |
| Sam & Max Hit the Road | MAC | | Original | | 8022133 | |
| Salvat Enciclopedia Interactiva | CDI | | Original | | B-44677-96 | |
| Salaryman Champ: Tatakau Salaryman サラリーマンチャンプ たたかうサラリーマン | KS573 | | Original | | A18 JA A02 | |
| Sakura Wars: So Long, My Love | WII | | Original | | RVL-SAKP-UKV-E0 | |
| Sakura Taisen Monogatari: Mysterious Paris: Special Disc サクラ大戦物語 ~ミステリアス巴里~ Special Disc | PC | | Promo | | | |
| Saints Row: The Third: The Full Package (Disc 1) (DLC Installer) | XBOX360 | | Original | | TQ-2213 | |
| Saints Row 2 | PC | | Covermount | | | |
| Saints Row (Assets Disk) | PC | | Press Kit | | | |
| Saints Row | XBOX360 | | Classics | | TQ-2001 | |
| Saints Row | XBOX360 | | Demo | | IM-2024 | |
| Saint Hermit Studios E3 2001 Press Kit | PC | | Press Kit | | | |
| Saint Eyes セイントアイズ | PC | | TGL-2000 Series | | | |
| Saint Eyes セイントアイズ | PC | | Shokai Genteiban | | | |
| Sail with Columbus | VIS | | Original | | 25-6181 | |
| Saga: Rage of the Vikings | PC | | Covermount | | | |
| SaGa Frontier 2 | PSX | | Original | | SLES-02118 | |
| Safecracker | WII | | Original | | RVL-RQFE-USA | |
| Safar'Wii | WII | | Original | | RVL-RD6P-EUR-B0 | |
| Saddle Up with Pippa Funnell: Equestrian Champion | PC | | Original | | 782650-CF | |
| Sacrifice (Scapex Tutorial Video) | PC | | Preproduction | | | |
| Sacrifice | PC | | Bundle Version Hewlett Packard OEM | | CD-C951041-PC2E | |
| Sacrifice (Editors Press Kit) | PC | | Press Kit | | | |
| Sacrifice (Disc 3) (Poradnik do Edytora Scapex) | PC | | Original | | | |
| Sacred Plus (Disc 1) | PC | | Big Bytes | | | |
| The Sacred Mirror of Kofūn (Disc 3) | PC | | | | CKOF1096-3A | |
| The Sacred Mirror of Kofūn (Disc 2) | PC | | | | CKOF1096-2A | |
| The Sacred Mirror of Kofūn (Disc 1) (Installation) | PC | | | | CKOF1096-1A | |
| Sacred 2: Złota Edycja (Dysk 1) | PC | | Premium Games | | | |
| Sacred 2: Złota Edycja (Dysk 2) | PC | | Premium Games | | | |
| Sacred 2: Złota Edycja (Bonus Disc) | PC | | Premium Games | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Digital Press-Kit: Games Convention 2008) | PC | | Press Kit | | | |
| Sacred (Disc 2) | PC | | | | | |
| Sacred (Disc 1) | PC | | | | | |
| Sacra Terra: Angelic Night | PC | | Original | | | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Sable Maze: Sullivan River / Norwich Caves | PC | | | | 33471010US | |
| Sable Maze: Forbidden Garden & Twelve Fears | PC | | Original | | 33528010US | |
| Saban's Power Rangers: Time Force | PC | | Original | | | |
| Saban's Power Rangers Zeo Versus the Machine Empire | PC | | Original | | | |
| SAAR + AMOK PD CD-ROM Überarbeitete Version 12/93 | ACD | | Original | | | |
| S3d Game Pak | PC | | Bundle Version S3 OEM | | | |
| S²: Silent Storm (Disc 1) | PC | | Gold Edition | | ROSILENTST0007lab1 | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| S.T.A.L.K.E.R.: Clear Sky (Assets) | PC | | Press Kit | | | |
| Ryuutouden 龍闘伝 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 42 | | HME-213 | |
| Ryuuko no Ken 龍虎の拳 | PCE | | Sample | | | |
| Ryoujoku Costume Play 凌辱コスチュームプレイ | PC | | Taikenban | | | |
| Rymden | PC | | Original | | | |
| Rygar: The Battle of Argus | WII | | Beta | | | |
| Rygar: The Battle of Argus | WII | | Original | | RVL-RYGP-EUR | |
| Running Wild | PSX | | Preview | | SLUS 94272 | |
| Runes of Magic: Sonsuz Macera | PC | | Covermount | | | |
| Runes of Magic: Chapter IV: Lands of Despair | PC | | Covermount | | | |
| Runes of Magic | PC | | Original | | | |
| Rune II: Koruten no Kagi no Himitsu ルーンⅡ コルテンの鍵の秘密 | GC | | Taikenban | | DL-DOL-DR2J-DIS | |
| Rune Factory: Frontier | WII | | Original | | RVL-RUFP-EUR-B0 | |
| Rune Lost Kingdoms | GC | | Beta | | | |
| Rune ルーン | GC | | Original | | DL-DOL-GRNJ-JPN | |
| Runaway: A Twist of Fate | PC | | Original | | | |
| Runaway: A Twist of Fate | PC | | Covermount | | G2DVD0115 | |
| Runaway: A Road Adventure | PC | | FX Interactive Rerelease | | | |
| Runaway Αποδραση | PC | | Original | | | |
| Runabout 2 ランナバウト2 | PSX | | Taikenban | | SLPM 80510 | |
| Runabout ランナバウト | PSX | | Demo | | SLPM 80104 | |
| Rumble in the Void | PC | | Promo | | | |
| Rules of the Game | PC | | Original | | 04-22266CD | |
| Rugby League Live 2: World Cup Edition | XBOX360 | | | | HE-2009 | |
| Rugby 2005 | XBOX | | Original | | EA-097 | |
| Rugby 2005 (Disc 2) EA Sports Rugby 2005 | PC | | Serie Maxima II | | EAE08004553D2 | |
| Rugby 2005 (Disc 1) EA Sports Rugby 2005 | PC | | Serie Maxima II | | EAE08004553D | |
| Ruesselsheim | PC | | SierraOriginals | | | |
| Rudolph the Red-Nosed Reindeer | WII | | Original | | RVL-SRUE-USA-B0 | |
| Rudingard no Hikari ルディンガルドの光 | PC | | Original | | FLAME-001 | |
| Rubik's World | WII | | Beta | | | |
| Rubik's Puzzle World | WII | | Original | | RVL-RRZP-EUR | |
| RTL Biathlon 2009 | WII | | Original | | RVL-RVXP-EUR | |
| Les Royaumes D'Amalur: Reckoning | XBOX360 | | Original | | EA-2366 | |
| Royal Edoma Engine 王立エドマエンジン | PC | | Original | | MSCD-0020 | |
| Rowan's Battle of Britain | PC | | | | | |
| La Roue du Temps (Disc 2) | PC | | Original | | | |
| I Roteò e la Magia dello Specchio | PC | | Kinder e Ferrero | | | |
| Rosco McQueen | PSX | | Preview | | SCES-00257 | |
| Roots: Blood Knight Sion | PC | | Original | | | |
| Rooms: The Main Building | WII | | Demo | | RVL-DRME-USA-B0 | |
| Rondo Leaflet: Trial Edition 『ロンド・リーフレット』特典付体験版 | PC | | Taikenban | | | |
| Rond de Wereld met Jommeke: Jommeke in India | PC | | Original | | | |
| Rond de Wereld met Jommeke: Jommeke in Amazonië | PC | | Original | | | |
| Rome: Total War (Press Kit) | PC | | Press Kit | | | |
| Romdia Vol. 32: Koro Koro Tony ロムディアVOL.32 ころころトニー | PC | | Original | | FS-00040 | |
| Romdia Vol. 27: Return of Egypt ロムディアVOL.27 リターンオブエジプト | PC | | Original | | FS-00035 | |
| Romdia Vol. 26: Racing Dynamics Plus ロムディアVOL.26 レーシングダイナミクスプラス | PC | | Original | | FS-00034 | |
| ROM-NESQUE 2 ロムネスク2 | PC | | Original | | | |
| Rom Factory: Mega Play No. 8: Strategic-Games | PC | | | | | |
| Rom Factory: Mega Play No. 5: Arcade Classics | PC | | | | | |
| Rom Factory: Mega Play No. 3 | PC | | | | | |
| Rom Factory: Kid Fun No. 7 | PC | | | | | |
| Rom Factory: Kid Fun No. 6 | PC | | | | | |
| Rom Factory: Kid Fun No. 5 | PC | | | | | |
| Rom Factory: Kid Fun No. 3 | PC | | | | | |
| Rom Factory: Kid Fun No. 2 | PC | | | | | |
| Rom Factory: Action No. 8 | PC | | | | | |
| Rom Factory: Action No. 7 | PC | | | | | |
| Rom Factory: Action No. 6 | PC | | | | | |
| Rom Factory: Action No. 5 | PC | | | | | |
| Rom Factory: Action No. 4 | PC | | | | | |
| Rom Factory: Action No. 3 | PC | | | | | |
| Rom Factory: Action No. 2 | PC | | | | | |
| Rom Factory: Action No. 1 | PC | | | | | |
| Rolling | XBOX | | Original | | SC-007 | |
| RollerCoaster Tycoon 3: Soaked! | PC | | Original | | | |
| RollerCoaster Tycoon 3 | PC | | Rerelease | | Part # 25655CDA | |
| RollerCoaster Tycoon 3 | PC | | ABN AMRO | | 1013537 | |
| Rollerbot: Time Journey | PC | | Original | | | |
| Rollerbollen | CDI | | | | D/1999/7277/1 | |
| Roller Coaster World Deluxe | PC | | Original | | | |
| Roller Coaster World X3D Roller Coaster World | PC | | X3D | | | |
| Rollcage Stage II + Colony Wars: Red Sun (Press Disc 3) | PC | | Press Kit | | | |
| Rollcage Stage II | PSX | | Review | | | |
| Rollcage | PC | | Bundle Version ASUS OEM | | V096 | |
| Rollcage | PC | | Bundle Version Creative Labs OEM | | 17133290747 | |
| Rollcage Rollcage Competition Demo | PSX | | Demo | | SLED-01896 | |
| Roland Garros French Open Tennis 1997 | PC | | Original | | | |
| Roland Garros 2000 | PC | | Covermount | | | |
| Roland Garros 1998 | PC | | 4 Giochi Microids | | | |
| Roland Garros 1997 | PC | | Medium | | | |
| Roland Garros 1997 Tennis Roland Garros | PC | | Covermount | | SIAE 9825PA | |
| Roketz | PC | | Green Pepper | | | |
| Rogue Trooper: Quartz Zone Massacre | WII | | Original | | RVL-RRYP-EUR | |
| Rogue Ops | XBOX | | Beta | | | |
| Rogue Ops | GC | | Original | | DL-DOL-GP9E-USA | |
| Rodney's Funscreen | VIS | | Original | | 25-6152 | |
| Rocky Mountain Trophy Hunter: Alaskan Expedition | PC | | Original | | P/N 04-17440CDSL | |
| Rocky | GC | | Original | | DL-DOL-GRKE-USA | |
| Rocky | XBOX | | Demo | | US-020 | |
| Rockstar EPK: Electronic Press Kit: E3 Assets CD | PC | | Press Kit | | | |
| Rockstar + Take-Two Interactive | PC | | Press Kit | | | |
| Rockman X8 (Disc 2) | PC | | Original | | | |
| Rockman X8 (Disc 1) | PC | | Original | | | |
| Rockman X8 록맨X8 | PC | | X7+8 | | | |
| Rockman X7 록맨X7 | PC | | X7+8 | | | |
| Rockman X6 洛克人X6 | PC | | Bundle Version MSI OEM | | G71-0400029 | |
| Rockman X5 洛克人X5 | PC | | Original | | | |
| Rockman X3 ロックマンX3 | PC | | Original | | CAP.X3-01 | |
| Rockett's Secret Invitation | PC | | Original | | 107-10-2000 | |
| Rockett's New School | PC | | Original | | 100-10-2000 | |
| Rockett's New School | PC | | Software USA | | | |
| Rockett's First Dance Rockett's First Dance: Episode 4 | PC | | | | | |
| Rockett's Camp Adventures | PC | | Original | | 25614-0919 | |
| Rocket Science Game Sampler | PC | | | | | |
| Rock'N'Roll Adventures | WII | | Original | | RVL-RRAX-NOE | |
| Rock Revolution | XBOX360 | | Original | | KN-2016 | |
| Rock Revolution | WII | | Original | | RVL-RVLP-EUR | |
| Rock Band: Track Pack Volume 1 | WII | | Original | | RVL-RREE-USA | |
| Rock Band: Song Pack 2 | XBOX360 | | Original | | EA-2177 | |
| Rock Band: Metal Track Pack | XBOX360 | | Original | | EA-2253 | |
| Rock Band: Country Track Pack | XBOX360 | | Original | | EA-2250 | |
| Rock Band Track Pack: Classic Rock | WII | | Original | | RVL-R3ZE-USA | |
| Rock Band Track Pack: Classic Rock | XBOX360 | | Original | | EA-2224 | |
| Rock 'N' Roll | PC | | Miço'dan Süper Bilgisayar Oyunları | | | |
| Rock 'N Roll Your Own: A Music-Making CD-ROM Experience | PC | | Original | | CDRM1291270 | |
| Roboty: Interaktywny CD-ROM Edukacyjny | PC | | Covermount | | | |
| Robots | PC | | Demo | | MOS034 | |
| Robots | GC | | Original | | DL-DOL-GZQE-USA | |
| Robots | GC | | Original | | DL-DOL-GZQP-EUR | |
| Robots | PC | | Press Kit | | | |
| Robotron X | PSX | | Demo | | SLED-00515 | |
| Robotech: Battlecry | GC | | Original | | DL-DOL-GRBP-EUR | |
| Robotech: Battlecry | XBOX | | Original | | TM-002 | |
| The Robot Club | PC | | Original | | | |
| RoboRumble | PC | | Original | | | |
| Robo·Pit 2 ロボ・ピット2 | PSX | | Preview Taikenban | | SLPM 80135 | |
| Robo Warrior Games | PC | | | | | |
| Robinson's Requiem | AJCD | | Unlicensed | | CF3007 | |
| Robinson Crusoe | PC | | | | | |
| Robin Hood: La Leggenda di Sherwood | PC | | Covermount | | | |
| Robin Hood: La Leggenda di Sherwood | PC | | Covermount | | | |
| Robin Hood: Defender of the Crown | XBOX | | Original | | CC-012 | |
| Robert E. Lee: Civil War General | PC | | Original | | | |
| Robbit mon Dieu ロビット・モン・ジャ | PSX | | Taikenban | | PAPX 90098 | |
| RoadWorthy RoadWorthy: Advanced Driver Training | CDI | | Original | | HAS9303A | |
| RoadKill | GC | | Original | | DL-DOL-GOCE-USA | |
| Road Warrior | PC | | Original | | | |
| Road Trip: The Arcade Edition | GC | | Original | | DL-DOL-GROE-USA | |
| Road to India: Between Hell and Nirvana (Disc 2) | PC | | Original | | 67202302 | |
| Road to India: Between Hell and Nirvana (Disc 1) | PC | | Original | | 67202202 | |
| Road Rash | PC | | Demo | | | |
| Road Rash ロード・ラッシュ | 3DO | | Demonstration-ban | | FZ-SD1654 | |
| Road Adventures USA (Disc 3) | PC | | Scholastic | | TRA744AE-CD3 SP3 | |
| Road Adventures USA (Disc 2) | PC | | Scholastic | | TRA744AE-CD2 SP3 | |
| Road Adventures USA (Disc 1) | PC | | Scholastic | | TRA744AE-CD1 SP3 | |
| Road & Track Presents: The Need for Speed | PC | | Original | | M-28227-95 | |
| Road & Track Presents: The Need for Speed 니드 포 스피드 | 3DO | | Original | | GDT-GA251 | |
| Road & Track Presents: OverDrivin' オーバードライビン | 3DO | | Sampler CD | | IMP-SS0102 | |
| RLH: Run Like Hell | XBOX | | Original | | IP-006 | |
| Riviera: Yakusoku no Chi: Prelude Disc Riviera ~約束の地リヴィエラ~ prelude disc | PC | | Original | | | |
| La Riviera Vaudoise | CDI | | Original | | | |
| Riverworld Philip José Farmer's Riverworld | PC | | | | RIV-CD | |
| Riverdeep Bonus Pack Resource Disc | PC | | | | RRD-CD | |
| Riverboat Casino | PC | | Original | | | |
| The Riven: The Sequel to Myst + Journeyman Project 3: Legacy of Time | PC | | | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | | Rerelease | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | | | | | |
| Riven: The Sequel to Myst (Disc 2) | PSX | | Original | | SLES-11100 | |
| Rival Schools + Resident Evil 2 + Bloody Roar + Street Fighter EX Plus Alpha + Mr Domino + Victory Boxing 2 | PSX | | | | SLED-01756 | |
| Il Ritorno del Pirata Barbanera Le nuovissime avventure del nostro simpatico amico | PC | | Microforum | | | |
| Risk: The Game of Global Domination | PC | | Original | | 99003 | |